Search Results - "GULCHER, J. R"

Identification of a novel neuregulin 1 at-risk haplotype in Han schizophrenia Chinese patients, but no association with the Icelandic Scottish risk haplotype by LI, T, STEFANSSON, H, INGASON, A, GULCHER, J. R, STEFANSSON, K, COLLIER, D. A, GUDFINNSSON, E, CAI, G, LIU, X, MURRAY, R. M, STEINTHORSDOTTIR, V, JANUEL, D, GUDNADOTTIR, V. G, PETURSSON, H

“…To determine if neuregulin 1 (NRG1) is associated with schizophrenia in Asian populations, we investigated a Han Chinese population using both a family trio…”
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CDKN2A mutations and melanoma risk in the Icelandic population by Goldstein, A M, Stacey, S N, Olafsson, J H, Jonsson, G F, Helgason, A, Sulem, P, Sigurgeirsson, B, Benediktsdottir, K R, Thorisdottir, K, Ragnarsson, R, Kjartansson, J, Kostic, J, Masson, G, Kristjansson, K, Gulcher, J R, Kong, A, Thorsteinsdottir, U, Rafnar, T, Tucker, M A, Stefansson, K

“…Germline CDKN2A mutations have been observed in 20-40% of high risk, melanoma prone families; however, little is known about their prevalence in population…”
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Polymorphisms in hypocretin/orexin pathway genes and narcolepsy by OLAFSDOTTIR, B. R, RYE, D. B, SCAMMELL, T. E, MATHESON, J. K, STEFANSSON, K, GULCHER, J. R

“…The neuroexcitatory peptide hypocretin and its receptors are central to the pathophysiology of both human and animal models of the disease. In this study of…”
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A Genome-Wide Scan Reveals a Maternal Susceptibility Locus for Pre-Eclampsia on Chromosome 2p13 by Arngrímsson, Reynir, Siguróaróóttir, Sigrún, Frigge, Michael L., Bjarnaóóttir, Ragnheióur I., Jónsson, Thorlákur, Stefánsson, Hreinn, Baldursdóttir, Ásdís, Einarsdóttir, Anna S., Palsson, Birgir, Snorradôttir, Steinunn, Lachmeijer, A. M. A., Nicolae, Dan, Kong, Augustine, Bragason, Birkir Thor, Gulcher, Jeffrey R., Geirsson, Reynir Tómas, Stefánsson, Kári

“…Pre-eclampsia is a common and serious disease and a major cause of maternal and infant mortality. Antenatal care systems world-wide screen for signs of the…”
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Protection of privacy by third-party encryption in genetic research in Iceland by Gulcher, J R, Kristjánsson, K, Gudbjartsson, H, Stefánsson, K

“…As the new human genetics continues its dramatic expansion into many laboratories and medical institutions, the concern for the protection of the personal…”
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An Alternatively Spliced Region of the Human Hexabrachion Contains a Repeat of Potential N-glycosylation Sites by Gulcher, Jeffrey R., Nies, Donald E., Marton, Linda S., Stefansson, Kari

“…We have cloned and sequenced two cDNA molecules that code for parts of two forms of human hexabrachion. The smaller clone has a sequence that corresponds to…”
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The Mutation Rate in the Human mtDNA Control Region by Sigurðardóttir, Sigrún, Helgason, Agnar, Gulcher, Jeffrey R., Stefansson, Kári, Donnelly, Peter

“…The mutation rate of the mitochondrial control region has been widely used to calibrate human population history. However, estimates of the mutation rate in…”
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mtDNA and the Origin of the Icelanders: Deciphering Signals of Recent Population History by Helgason, Agnar, Sigurðardóttir, Sigrún, Gulcher, Jeffrey R., Ward, Ryk, Stefánsson, Kári

“…Previous attempts to investigate the origin of the Icelanders have provided estimates of ancestry ranging from a 98% British Isles contribution to an 86%…”
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Estimating Scandinavian and Gaelic Ancestry in the Male Settlers of Iceland by Helgason, Agnar, Sigurðardóttir, Sigrún, Nicholson, Jayne, Sykes, Bryan, Hill, Emmeline W., Bradley, Daniel G., Bosnes, Vidar, Gulcher, Jeffery R., Ward, Ryk, Stefánsson, Kári

“…We present findings based on a study of Y-chromosome diallelic and microsatellite variation in 181 Icelanders, 233 Scandinavians, and 283 Gaels from Ireland…”
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Mapping of a familial essential tremor gene, FET1 , to chromosome 3q13 by Gulcher, Jeffrey R, Jónsson, Þorlákur, Kong, Augustine, Kristjánsson, Kristleifur, Frigge, Michael L, Kárason, Ari, Einarsdóttir, Ingibjörg E, Stefánsson, Hreinn, Einarsdóttir, Anna S, Sigurdardðttir, Sigrún, Baldursson, Sigurður, Björnsdóttir, Sóley, Hrafnkelsdóttir, Soffía M, Jakobsson, Finnbogi, Benedickz, John, Stefánsson, Kári

“…Essential tremor (ET), the most common movement disorder in humans, appears to be inherited as an autosomal dominant trait in many families. The familial form…”
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The Icelandic Healthcare Database and Informed Consent by Gulcher, Jeffrey R, Stefánsson, Kári

“…Modern information technology is rapidly changing how new knowledge is discovered in most fields of science, including medicine. This technology offers…”
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Validation of the deCODE Migraine Questionnaire (DMQ3) for use in genetic studies by Kirchmann, M., Seven, E., Björnsson, Á., Björnssdóttir, G., Gulcher, J. R., Stefánsson, K., Olesen, J.

“…We assessed the reliability of the diagnosis of migraine with aura (MA) and migraine without aura (MO) based on the third edition of the deCODE Migraine…”
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Neuregulin 1 in schizophrenia: out of Iceland by Stefánsson, H, Thorgeirsson, T E, Gulcher, J R, Stefánsson, K

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Structure of the Human Hexabrachion (Tenascin) Gene by Gulcher, Jeffrey R., Nies, Donald E., Alexakos, Mark J., Ravikant, Neeju A., Sturgill, Michael E., Marton, Linda S., Stefansson, Kari

“…The structure of the gene encoding human hexabrachion (tenascin) has been determined from overlapping clones isolated from a human genomic bacteriophage…”
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Binding of Hexabrachions to Heparin and DNA by Marton, L S, Gulcher, J R, Stefansson, K

“…Hexabrachions are extracellular proteins expressed in certain tissues and at specific points in development. cDNA sequencing has revealed that they contain a…”
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Expression of the Oligodendrocyte‐Myelin Glycoprotein by Neurons in the Mouse Central Nervous System by Habib, Amyn A., Marton, Linda S., Allwardt, Brenda, Gulcher, Jeffrey R., Mikol, Daniel D., Högnason, Thorbergur, Chattopadhyay, Naibedya, Stefansson, Kári

“…: The oligodendrocyte‐myelin glycoprotein (OMgp) is a 110‐kDa glycosylphosphatidylinositol‐linked protein that was initially identified as a myelin‐specific…”
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Two Large Glycosylated Polypeptides Found in Myelinating Oligodendrocytes but not in Myelin by Gulcher, Jeffrey R., Marton, Linda S., Stefansson, Kari

“…Previous work has shown that high molecular weight polypeptides sharing epitopes with myelin-associated glycoprotein are transiently expressed in developing…”
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Ethics of population genomics research by Gulcher, Jeffrey R, Stefansson, Kari

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The Oligodendrocyte-Myelin Glycoprotein Belongs to a Distinct Family of Proteins and Contains the HNK-1 Carbohydrate by Mikol, Daniel D., Gulcher, Jeffrey R., Stefansson, Kari

“…The complete primary structure of the human oligodendrocyte-myelin glycoprotein (OMgp), a glycophospholipid-linked membrane protein of oligodendrocytes and…”
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The OMgp gene, a second growth suppressor within the NF1 gene by HABIB, A. A, GULCHER, J. R, HÖGNASON, T, ZHENG, L, STEFANSSON, K

“…The Oligodendrocyte-Myelin glycoprotein gene (OMgp) is placed within an intron of the NF1 gene. Neurofibromin, the product of NF1, acts as a RasGAP and…”
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