Search Results - "GUIQING CAI"

Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes by Daskalakis, Nikolaos P., Cohen, Hagit, Cai, Guiqing, Buxbaum, Joseph D., Yehuda, Rachel

“…Significance Because posttraumatic stress disorder (PTSD) occurs in a subset of trauma-exposed persons, expression profiling in the context of an animal model…”
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Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks by Yehuda, Rachel, Cai, Guiqing, Golier, Julia A, Sarapas, Casey, Galea, Sandro, Ising, Marcus, Rein, Theo, Schmeidler, James, Müller-Myhsok, Bertram, Holsboer, Florian, Buxbaum, Joseph D

“…Background Although genetic risk factors for posttraumatic stress disorder (PTSD) in similarly traumatized cohorts can be confounded with risk for type of…”
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Personalized medicine of non-gene-specific chemotherapies for non-small cell lung cancer by Jiang, Wenxiao, Cai, Guiqing, Hu, Peter, Wang, Yue

“…Non-small cell lung cancer is recognized as the deadliest cancer across the globe. In some areas, it is more common in women than even breast and cervical…”
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Personalized medicine in non-small cell lung cancer: a review from a pharmacogenomics perspective by Jiang, Wenxiao, Cai, Guiqing, Hu, Peter C., Wang, Yue

“…Non-small cell lung cancer is a prevalent and rapidly-expanding challenge to modern medicine. While generalized medicine with traditional chemotherapy yielded…”
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Prospective investigation of autism and genotype-phenotype correlations in 22q13 deletion syndrome and SHANK3 deficiency by Soorya, Latha, Kolevzon, Alexander, Zweifach, Jessica, Lim, Teresa, Dobry, Yuriy, Schwartz, Lily, Frank, Yitzchak, Wang, A Ting, Cai, Guiqing, Parkhomenko, Elena, Halpern, Danielle, Grodberg, David, Angarita, Benjamin, Willner, Judith P, Yang, Amy, Canitano, Roberto, Chaplin, William, Betancur, Catalina, Buxbaum, Joseph D

“…22q13 deletion syndrome, also known as Phelan-McDermid syndrome, is a neurodevelopmental disorder characterized by intellectual disability, hypotonia, delayed…”
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AnnTools: a comprehensive and versatile annotation toolkit for genomic variants by MAKAROV, Vladimir, O'GRADY, Tina, GUIQING CAI, LIHM, Jayon, BUXBAUM, Joseph D, YOON, Seungtai

“…AnnTools is a versatile bioinformatics application designed for comprehensive annotation of a full spectrum of human genome variation: novel and known…”
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Whole-Exome Sequencing Links a Variant in DHDDS to Retinitis Pigmentosa by Züchner, Stephan, Dallman, Julia, Wen, Rong, Beecham, Gary, Naj, Adam, Farooq, Amjad, Kohli, Martin A., Whitehead, Patrice L., Hulme, William, Konidari, Ioanna, Edwards, Yvonne J.K., Cai, Guiqing, Peter, Inga, Seo, David, Buxbaum, Joseph D., Haines, Jonathan L., Blanton, Susan, Young, Juan, Alfonso, Eduardo, Vance, Jeffery M., Lam, Byron L., Peričak-Vance, Margaret A.

“…Increasingly, mutations in genes causing Mendelian disease will be supported by individual and small families only; however, exome sequencing studies have thus…”
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Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly by Buxbaum, Joseph D., Cai, Guiqing, Chaste, Pauline, Nygren, Gudrun, Goldsmith, Juliet, Reichert, Jennifer, Anckarsäter, Henrik, Rastam, Maria, Smith, Christopher J., Silverman, Jeremy M., Hollander, Eric, Leboyer, Marion, Gillberg, Christopher, Verloes, Alain, Betancur, Catalina

“…Mutations in the PTEN gene are associated with a broad spectrum of disorders, including Cowden syndrome (CS), Bannayan–Riley–Ruvalcaba syndrome, Proteus…”
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Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities by Naj, Adam C, Beecham, Gary W, Martin, Eden R, Gallins, Paul J, Powell, Eric H, Konidari, Ioanna, Whitehead, Patrice L, Cai, Guiqing, Haroutunian, Vahram, Scott, William K, Vance, Jeffery M, Slifer, Michael A, Gwirtsman, Harry E, Gilbert, John R, Haines, Jonathan L, Buxbaum, Joseph D, Pericak-Vance, Margaret A

“…Genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) have consistently observed strong evidence of association with polymorphisms in…”
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Characterization of SLITRK1 variation in obsessive-compulsive disorder by Ozomaro, Uzoezi, Cai, Guiqing, Kajiwara, Yuji, Yoon, Seungtai, Makarov, Vladimir, Delorme, Richard, Betancur, Catalina, Ruhrmann, Stephan, Falkai, Peter, Grabe, Hans Jörgen, Maier, Wolfgang, Wagner, Michael, Lennertz, Leonhard, Moessner, Rainald, Murphy, Dennis L, Buxbaum, Joseph D, Züchner, Stephan, Grice, Dorothy E

“…Obsessive compulsive disorder (OCD) is a syndrome characterized by recurrent and intrusive thoughts and ritualistic behaviors or mental acts that a person…”
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Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks by Sarapas, Casey, Cai, Guiqing, Bierer, Linda M, Golier, Julia A, Galea, Sandro, Ising, Marcus, Rein, Theo, Schmeidler, James, Müller-Myhsok, Bertram, Uhr, Manfred, Holsboer, Florian, Buxbaum, Joseph D, Yehuda, Rachel

“…We have previously reported the differential expression of 17 probe sets in survivors of the 9/11 attacks with current posttraumatic stress disorder (PTSD)…”
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An analysis of candidate autism loci on chromosome 2q24-q33: Evidence for association to the STK39 gene by Ramoz, Nicolas, Cai, Guiqing, Reichert, Jennifer G., Silverman, Jeremy M., Buxbaum, Joseph D.

“…A susceptibility locus for autism was identified to the chromosome 2q24–q33 region in independent cohorts of families, especially in subsets clinically defined…”
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Evidence against a role for rare ADAM10 mutations in sporadic Alzheimer Disease by Cai, Guiqing, Atzmon, Gil, Naj, Adam C, Beecham, Gary W, Barzilai, Nir, Haines, Jonathan L, Sano, Mary, Pericak-Vance, Margaret, Buxbaum, Joseph D

“…Abstract The Alzheimer amyloid protein precursor (APP) is subject to proteolysis by ADAM10 and ADAM17, precluding the formation of Aβ. Recently, coding…”
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Lessons learned from expanded reproductive carrier screening in self‐reported Ashkenazi, Sephardi, and Mizrahi Jewish patients by Akler, Gidon, Birch, Ashley H., Schreiber‐Agus, Nicole, Cai, Xiaoqiang, Cai, Guiqing, Shi, Lisong, Yu, Chunli, Larmore, Anastasia M., Mendiratta‐Vij, Geetu, Elkhoury, Lama, Dillon, Mitchell W., Zhu, Jun, Mclellan, Andrew S., Suer, Funda E., Webb, Bryn D., Schadt, Eric E., Kornreich, Ruth, Edelmann, Lisa

“…Background Next‐generation sequencing (NGS)‐based panels have gained traction as a strategy for reproductive carrier screening. Their value for screening…”
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Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: efficient identification of known microduplications and identification of a novel microduplication in ASMT by Cai, Guiqing, Edelmann, Lisa, Goldsmith, Juliet E, Cohen, Ninette, Nakamine, Alisa, Reichert, Jennifer G, Hoffman, Ellen J, Zurawiecki, Danielle M, Silverman, Jeremy M, Hollander, Eric, Soorya, Latha, Anagnostou, Evdokia, Betancur, Catalina, Buxbaum, Joseph D

“…It has previously been shown that specific microdeletions and microduplications, many of which also associated with cognitive impairment (CI), can present with…”
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Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia by Vares, Maria, Saetre, Peter, Deng, Hong, Cai, Guiqing, Liu, Xiehe, Hansen, Thomas, Rasmussen, Henrik B., Werge, Thomas, Melle, Ingrid, Djurovic, Srdjan, Andreassen, Ole A., Agartz, Ingrid, Hall, Håkan, Terenius, Lars, Jönsson, Erik G.

“…Different lines of evidence indicate that methylenetetrahydrofolate reductase (MTHFR) functional gene polymorphisms, causative in aberrant folate–homocysteine…”
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Family-based association study of TPH1 and TPH2 polymorphisms in autism by Ramoz, Nicolas, Cai, Guiqing, Reichert, Jennifer G., Corwin, Thomas E., Kryzak, Lauren A., Smith, Christopher J., Silverman, Jeremy M., Hollander, Eric, Buxbaum, Joseph D.

“…The TPH1 and TPH2 genes encode the rate‐limiting enzymes that control serotonin biosynthesis, and serotonin is clearly altered in autism. In the current study,…”
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MOLECULAR TESTING FOR BIRT-HOGG-DUBE SYNDROME IN PATIENTS WITH ISOLATED PULMONARY FINDINGS: A COMMERCIAL LABORATORY'S EXPERIENCE by NORDQUIST, ERIN N, CAI, GUIQING, M TULLY, DIANA

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Brain and blood gene expression pathways associated with susceptibility to PTSD by Daskalakis, Nikolaos P., Buxbaum, Joseph, Flory, Janine D., Cai, Guiqing, Shen, Li, Bierer, Linda M., Cohen, Hagit, Yehuda, Rachel

“…Abstract only…”
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Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly by Buxbaum, Joseph D, Cai, Guiqing, Nygren, Gudrun, Chaste, Pauline, Delorme, Richard, Goldsmith, Juliet, Råstam, Maria, Silverman, Jeremy M, Hollander, Eric, Gillberg, Christopher, Leboyer, Marion, Betancur, Catalina

“…Sotos syndrome is an overgrowth syndrome characterized by macrocephaly, advanced bone age, characteristic facial features, and learning disabilities, caused by…”
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