Search Results - "GUIOCHON, Georges"

Monolithic columns in high-performance liquid chromatography by Guiochon, Georges

“…Monolithic media have been used for various niche applications in gas or liquid chromatography for a long time. Only recently did they acquire a major…”
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Shell particles, trials, tribulations and triumphs by Guiochon, Georges, Gritti, Fabrice

“…The concept of pellicular particles was imagined by Horváth and Lipsky fifty years ago. They were initially intended for the analysis of macromolecules. Later,…”
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The limits of the separation power of unidimensional column liquid chromatography by Guiochon, Georges

“…The practical limit of the separation power of HPLC depends on time, money, and skill. That is it depends on the time available for the analysis, on the…”
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Mass transfer kinetics, band broadening and column efficiency by Gritti, Fabrice, Guiochon, Georges

“…Important progress was recently made in our understanding of the physico-chemical aspects of mass transfer kinetics in chromatographic columns, in methods used…”
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Surface diffusion in reversed-phase liquid chromatography by Miyabe, Kanji, Guiochon, Georges

“…More than 40 years ago, Giddings pointed out in “Dynamics of Chromatography” that surface diffusion should become an important research topic in the kinetics…”
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A protocol for the measurement of all the parameters of the mass transfer kinetics in columns used in liquid chromatography by Gritti, Fabrice, Guiochon, Georges

“…Band broadening in chromatography results from the combination of the dispersive effects that are associated with the different steps involved in the migration…”
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Complete Temperature Profiles in Ultra-High-Pressure Liquid Chromatography Columns by Gritti, Fabrice, Guiochon, Georges

“…The temperature profiles were calculated along and across seven packed columns (lengths 30, 50, 100, and 150 mm, i.d., 1 and 2.1 mm, all packed with Acquity…”
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Influence of Viscous Friction Heating on the Efficiency of Columns Operated under Very High Pressures by Gritti, Fabrice, Martin, Michel, Guiochon, Georges

“…When columns packed with very fine particles are operated at high mobile phase velocities, the friction of the mobile phase percolating through the column bed…”
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Physical properties and structure of fine core-shell particles used as packing materials for chromatography : Relationships between particle characteristics and column performance by Gritti, Fabrice, Leonardis, Irene, Abia, Jude, Guiochon, Georges

“…The recent development of new brands of packing materials made of fine porous-shell particles, e.g., Halo and Kinetex, has brought great improvements in…”
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Implementations of two-dimensional liquid chromatography by Guiochon, Georges, Marchetti, Nicola, Mriziq, Khaled, Shalliker, R.Andrew

“…Today scientists must deal with complex samples that either cannot be adequately separated using one-dimensional chromatography or that require an inordinate…”
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New insights on mass transfer kinetics in chromatography by Gritti, Fabrice, Guiochon, Georges

“…The mass transfer kinetics of thiourea, phenol, ethylbenzene, propylbenzene, butylbenzene, and amylbenzene were studied on a Gemini‐C18 (5 μm, 110 A˚, 375…”
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Importance of sample intraparticle diffusivity in investigations of the mass transfer mechanism in liquid chromatography by Gritti, Fabrice, Guiochon, Georges

“…The effective diffusivity of a nonretained (thiourea) and of a strongly retained (phenol) compounds were measured with the peak parking method in two different…”
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Mass transfer mechanism in hydrophilic interaction chromatography by Gritti, Fabrice, Guiochon, Georges

“…•The mass transfer mechanism in HILIC columns was investigated in depth.•The overall HETP depends weakly on the retention factor of the analyte.•The…”
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Adsorption behaviors of neutral and ionizable compounds on hybrid stationary phases in the absence (BEH-C18) and the presence (CSH-C18) of immobile surface charges by Gritti, Fabrice, Guiochon, Georges

“…► The adsorption behavior of caffeine and nortriptyline was studied on two RPLC/hybrid phases. ► The bands were eluted with a low ionic strength buffer. ► The…”
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Ultra high pressure liquid chromatography Column permeability and changes of the eluent properties by GRITTI, Fabrice, GUIOCHON, Georges

“…The behavior of four similar liquid chromatography columns (2.1mm i.d. x 30, 50, 100, and 150 mm, all packed with fine particles, average d(p) approximately…”
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Exact peak compression factor in linear gradient elution : I. Theory by Gritti, Fabrice, Guiochon, Georges

“…The only existing expression for the peak compression factor in linear gradient elution chromatography assumes that the linear-solvent-strength model (LSSM)…”
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The relative importance of the adsorption and partitioning mechanisms in hydrophilic interaction liquid chromatography by Gritti, Fabrice, Höltzel, Alexandra, Tallarek, Ulrich, Guiochon, Georges

“…•Original model of effective diffusion along packed beds of mesoporous particles.•Model enables differentiation between adsorption and partitioning in…”
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Measurement of the eddy diffusion term in chromatographic columns. I. Application to the first generation of 4.6mm I.D. monolithic columns by Gritti, Fabrice, Guiochon, Georges

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General HETP Equation for the Study of Mass-Transfer Mechanisms in RPLC by Gritti, Fabrice, Guiochon, Georges

“…Classical HETP equations including the Van Deemter and the Knox equations, are semiempirical, approximate equations that provide apparent mass-transfer…”
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Measurement of the eddy dispersion term in chromatographic columns: III. Application to new prototypes of 4.6mm I.D. monolithic columns by Gritti, Fabrice, Guiochon, Georges

“…► We measured mass transfer kinetics in silica monolithic columns of the second generation. ► We used four 4.6mm × 100mm research samples from Merck KGaA. ► We…”
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