Search Results - "GUINDO, Merepen A"
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A comprehensive analysis of drug resistance molecular markers and Plasmodium falciparum genetic diversity in two malaria endemic sites in Mali
Published in Malaria journal (12-11-2019)“…Drug resistance is one of the greatest challenges of malaria control programme in Mali. Recent advances in next-generation sequencing (NGS) technologies…”
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Ultra-sensitive RDT performance and antigen dynamics in a high-transmission Plasmodium falciparum setting in Mali
Published in Malaria journal (03-09-2020)“…The recent expansion of tools designed to accurately quantify malaria parasite-produced antigens has enabled us to evaluate the performance of rapid diagnostic…”
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Seroprevalence of SARS‐CoV‐2 Antibodies and Associated Factors in Bamako, Mali: A Population‐Based Cross‐Sectional Study in September 2022
Published in Influenza and other respiratory viruses (01-07-2024)“…ABSTRACT Background The sero‐epidemiological characteristics of SARS‐CoV‐2 infections in Mali are not yet well understood. This study assessed SARS‐CoV‐2…”
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Seroreactivity of the Severe Acute Respiratory Syndrome Coronavirus 2 Recombinant S Protein, Receptor-Binding Domain, and Its Receptor-Binding Motif in COVID-19 Patients and Their Cross-Reactivity With Pre-COVID-19 Samples From Malaria-Endemic Areas
Published in Frontiers in immunology (27-04-2022)“…Despite the global interest and the unprecedented number of scientific studies triggered by the COVID-19 pandemic, few data are available from developing and…”
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A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali
Published in Vaccine (18-05-2009)“…Abstract A double blind, randomized, controlled Phase 2 clinical trial was conducted to assess the safety, immunogenicity, and biologic impact of the vaccine…”
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Ex-vivo Sensitivity of Plasmodium falciparum to Common Anti-malarial Drugs: The Case of Kéniéroba, a Malaria Endemic Village in Mali
Published in Drugs in R&D (01-09-2020)“…Background In 2006, the National Malaria Control Program in Mali recommended artemisinin-based combination therapy as the first-line treatment for…”
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A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel® + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults
Published in Vaccine (09-12-2009)“…Abstract A double blind, randomized and controlled Phase 1 clinical trial was conducted to assess the safety and immunogenicity in malaria-exposed adults of…”
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Safety and efficacy of a three-dose regimen of Plasmodium falciparum sporozoite vaccine in adults during an intense malaria transmission season in Mali: a randomised, controlled phase 1 trial
Published in The Lancet infectious diseases (01-03-2022)“…WHO recently approved a partially effective vaccine that reduces clinical malaria in children, but increased vaccine activity is required to pursue malaria…”
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Malaria transmission-blocking vaccines Pfs230D1-EPA and Pfs25-EPA in Alhydrogel in healthy Malian adults; a phase 1, randomised, controlled trial
Published in The Lancet infectious diseases (01-11-2023)“…Malaria transmission-blocking vaccines target mosquito-stage parasites and will support elimination programmes. Gamete vaccine Pfs230D1-EPA/Alhydrogel induced…”
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Safety and immunogenicity of Pfs25H-EPA/Alhydrogel, a transmission-blocking vaccine against Plasmodium falciparum: a randomised, double-blind, comparator-controlled, dose-escalation study in healthy Malian adults
Published in The Lancet infectious diseases (01-09-2018)“…Pfs25H-EPA is a protein-protein conjugate transmission-blocking vaccine against Plasmodium falciparum that is safe and induces functional antibodies in…”
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Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine
Published in Malaria journal (19-01-2011)“…A Phase 1-2b study of the blood stage malaria vaccine AMA1-C1/Alhydrogel was conducted in 336 children in Donéguébougou and Bancoumana, Mali. In the Phase 2…”
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Normal Clinical Laboratory Ranges by Age and Sex, and Impact on Study Screening Outcomes in Rural Mali
Published in The American journal of tropical medicine and hygiene (01-05-2024)“…The interpretation of a laboratory test result requires an appropriate reference range established in healthy subjects, and normal ranges may vary by factors…”
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Promoting Good Clinical Laboratory Practices and Laboratory Accreditation to Support Clinical Trials in Sub-Saharan Africa
Published in The American journal of tropical medicine and hygiene (01-04-2012)“…Laboratory capacity in the developing world frequently lacks quality management systems (QMS) such as good clinical laboratory practices, proper safety…”
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Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial
Published in The Lancet infectious diseases (01-05-2017)“…Summary Background Plasmodium falciparum sporozite (PfSPZ) Vaccine is a metabolically active, non-replicating, whole malaria sporozoite vaccine that has been…”
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Safety and immunogenicity of Pfs25H-EPA/Alhydrogel®, a transmission blocking vaccine against Plasmodium falciparum: a randomized, double-blind, comparator-controlled, dose-escalation study in healthy malaria exposed Malian adults
Published in The Lancet infectious diseases (27-07-2018)Get full text
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A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel®+CPG 7909 vaccine forPlasmodium falciparummalaria in semi-immune Malian adults
Published in Vaccine (09-12-2009)“…A double blind, randomized and controlled Phase 1 clinical trial was conducted to assess the safety and immunogenicity in malaria-exposed adults of…”
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