Search Results - "GUINANE, Caitriona M"

Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ by Guinane, Caitriona M., Cotter, Paul D.

“…The human gut microbiota has become the subject of extensive research in recent years and our knowledge of the resident species and their potential functional…”
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Beneficial modulation of the gut microbiota by Walsh, Calum J., Guinane, Caitriona M., O’Toole, Paul W., Cotter, Paul D.

“…The human gut microbiota comprises approximately 100 trillion microbial cells and has a significant effect on many aspects of human physiology including…”
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The impact of the human microbiome in tumorigenesis, cancer progression, and biotherapeutic development by Doocey, Claire M, Finn, Karen, Murphy, Craig, Guinane, Caitriona M

“…Cancer impacts millions of lives globally each year, with approximately 10 million cancer-related deaths recorded worldwide in 2020. Mounting research has…”
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High-Throughput Sequencing Reveals the Incomplete, Short-Term Recovery of Infant Gut Microbiota following Parenteral Antibiotic Treatment with Ampicillin and Gentamicin by FOUHY, Fiona, GUINANE, Caitriona M, COTTER, Paul D, HUSSEY, Seamus, WALL, Rebecca, RYAN, C. Anthony, DEMPSEY, Eugene M, MURPHY, Brendan, ROSS, R. Paul, FITZGERALD, Gerald F, STANTON, Catherine

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Tn6188 - a novel transposon in Listeria monocytogenes responsible for tolerance to benzalkonium chloride by Müller, Anneliese, Rychli, Kathrin, Muhterem-Uyar, Meryem, Zaiser, Andreas, Stessl, Beatrix, Guinane, Caitriona M, Cotter, Paul D, Wagner, Martin, Schmitz-Esser, Stephan

“…Controlling the food-borne pathogen Listeria (L.) monocytogenes is of great importance from a food safety perspective, and thus for human health. The…”
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In silico identification of bacteriocin gene clusters in the gastrointestinal tract, based on the Human Microbiome Project's reference genome database by Walsh, Calum J, Guinane, Caitriona M, Hill, Colin, Ross, R Paul, O'Toole, Paul W, Cotter, Paul D

“…The human gut microbiota comprises approximately 100 trillion microbial cells which significantly impact many aspects of human physiology - including…”
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First evidence of production of the lantibiotic nisin P by Garcia-Gutierrez, Enriqueta, O’Connor, Paula M., Saalbach, Gerhard, Walsh, Calum J., Hegarty, James W., Guinane, Caitriona M., Mayer, Melinda J., Narbad, Arjan, Cotter, Paul D.

“…Nisin P is a natural nisin variant, the genetic determinants for which were previously identified in the genomes of two Streptococcus species, albeit with no…”
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Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus by Lowder, Bethan V, Guinane, Caitriona M, Ben Zakour, Nouri L, Weinert, Lucy A, Conway-Morris, Andrew, Cartwright, Robyn A, Simpson, A. John, Rambaut, Andrew, Nübel, Ulrich, Fitzgerald, J. Ross

“…The impact of globalization on the emergence and spread of pathogens is an important veterinary and public health issue. Staphylococcus aureus is a notorious…”
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Potential Use of Biotherapeutic Bacteria to Target Colorectal Cancer-Associated Taxa by Lawrence, Garreth W, Begley, Máire, Cotter, Paul D, Guinane, Caitriona M

“…The role of the gut microbiome in human health and disease is the focus of much attention. It has been widely agreed upon that our gut bacteria play a role in…”
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Bacteriophages φMR299-2 and φNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells by Alemayehu, Debebe, Casey, Pat G, McAuliffe, Olivia, Guinane, Caitriona M, Martin, James G, Shanahan, Fergus, Coffey, Aidan, Ross, R Paul, Hill, Colin

“…Pseudomonas aeruginosa is a common cause of infection in the lungs of patients with cystic fibrosis (CF). In addition, biofilm formation and antibiotic…”
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Effect of a bacteriocin-producing Streptococcus salivarius on the pathogen Fusobacterium nucleatum in a model of the human distal colon by Lawrence, Garreth W., McCarthy, Niamh, Walsh, Calum J., Kunyoshi, Tais M., Lawton, Elaine M., O'Connor, Paula M., Begley, Máire, Cotter, Paul D., Guinane, Caitriona M.

“…The gut microbiome is a vast reservoir of microbes, some of which produce antimicrobial peptides called bacteriocins that may inhibit specific bacteria…”
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A novel core genome-encoded superantigen contributes to lethality of community-associated MRSA necrotizing pneumonia by Wilson, Gillian J, Seo, Keun Seok, Cartwright, Robyn A, Connelley, Timothy, Chuang-Smith, Olivia N, Merriman, Joseph A, Guinane, Caitriona M, Park, Joo Youn, Bohach, Gregory A, Schlievert, Patrick M, Morrison, W Ivan, Fitzgerald, J Ross

“…Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune modulation and severe systemic illnesses such as Staphylococcus aureus…”
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Bacteriocin production: a relatively unharnessed probiotic trait? by Hegarty, James W, Guinane, Caitriona M, Ross, R Paul, Hill, Colin, Cotter, Paul D

“…Probiotics are "live microorganisms which, when consumed in adequate amounts, confer a health benefit to the host". A number of attributes are highly sought…”
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Adaptation of Staphylococcus aureus to ruminant and equine hosts involves SaPI-carried variants of von Willebrand factor-binding protein by Viana, David, Blanco, José, Tormo-Más, María Ángeles, Selva, Laura, Guinane, Caitriona M, Baselga, Rafael, Corpa, Juan M, Lasa, Íñigo, Novick, Richard P, Fitzgerald, J. Ross, Penadés, José R

“…Staphylococci adapt specifically to various animal hosts by genetically determined mechanisms that are not well understood. One such adaptation involves the…”
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Assessing the Contributions of the LiaS Histidine Kinase to the Innate Resistance of Listeria monocytogenes to Nisin, Cephalosporins, and Disinfectants by COLLINS, Barry, GUINANE, Caitriona M, COTTER, Paul D, HILL, Colin, ROSS, R. Paul

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Microbial composition of human appendices from patients following appendectomy by Guinane, Caitriona M, Tadrous, Amany, Fouhy, Fiona, Ryan, C Anthony, Dempsey, Eugene M, Murphy, Brendan, Andrews, Emmet, Cotter, Paul D, Stanton, Catherine, Ross, R Paul

“…The human appendix has historically been considered a vestige of evolutionary development with an unknown function. While limited data are available on the…”
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Inhibition of Clinical MRSA Isolates by Coagulase Negative Staphylococci of Human Origin by Twomey, Ellen, O'Connor, Paula M, Coffey, Aidan, Kiste, Maija, Guinane, Caitriona M, Hill, Colin, Field, Des, Begley, Máire

“…is frequently highlighted as a priority for novel drug research due to its pathogenicity and ability to develop antibiotic resistance. Coagulase-negative…”
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In Vitro and In Silico Based Approaches to Identify Potential Novel Bacteriocins from the Athlete Gut Microbiome of an Elite Athlete Cohort by Wosinska, Laura, Walsh, Calum J, O'Connor, Paula M, Lawton, Elaine M, Cotter, Paul D, Guinane, Caitriona M, O'Sullivan, Orla

“…Exercise reduces inflammation, fatigue, and aids overall health. Additionally, physical fitness has been associated with desirable changes in the community…”
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A Profile Hidden Markov Model to investigate the distribution and frequency of LanB-encoding lantibiotic modification genes in the human oral and gut microbiome by Walsh, Calum J, Guinane, Caitriona M, O' Toole, Paul W, Cotter, Paul D

“…The human microbiota plays a key role in health and disease, and bacteriocins, which are small, bacterially produced, antimicrobial peptides, are likely to…”
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Contribution of Penicillin-Binding Protein Homologs to Antibiotic Resistance, Cell Morphology, and Virulence of Listeria monocytogenes EGDe by GUINANE, Caitriona M, COTTER, Paul D, ROSS, R. Paul, HILL, Colin

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