Search Results - "GUILET, David"
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Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
Published in Nature communications (20-09-2018)“…Systemic vitamin E metabolites have been proposed as signaling molecules, but their physiological role is unknown. Here we show, by library screening of…”
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2
QTL analysis and candidate gene mapping for the polyphenol content in cider apple
Published in PloS one (01-10-2014)“…Polyphenols have favorable antioxidant potential on human health suggesting that their high content is responsible for the beneficial effects of apple…”
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3
Influence of Maceration Solvent on Chemical Composition of Gemmotherapy Macerates—A Case Study on Olea europaea Young Shoots
Published in Nutraceuticals (01-12-2023)“…Gemmotherapy, a natural therapy based on bud macerates, has recently gained importance in the field of food supplements. However, two coexisting extraction…”
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4
Comparison of two methods, UHPLC-UV and UHPLC-MS/MS, for the quantification of polyphenols in cider apple juices
Published in Molecules (Basel, Switzerland) (22-08-2013)“…The aim of this study was to develop faster and more efficient phenotyping methods for in-depth genetic studies on cider apple progeny. The UHPLC…”
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5
Bioguided fractionation and isolation of natural inhibitors of advanced glycation end-products (AGEs) from Calophyllum flavoramulum
Published in Phytochemistry (Oxford) (01-06-2012)“…Isolation and identification of amentoflavone 1 and 3-methoxy-2-hydroxyxanthone 2 as very potent advanced glycation end-products (AGEs) inhibitors and of…”
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6
Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters
Published in Frontiers in pharmacology (12-04-2019)“…is the bacillus responsible for Buruli ulcer, an infectious disease and the third most important mycobacterial disease worldwide, after tuberculosis and…”
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7
A Descriptive Chemical Composition of Concentrated Bud Macerates through an Optimized SPE-HPLC-UV-MS2 Method—Application to Alnus glutinosa, Ribes nigrum, Rosa canina, Rosmarinus officinalis and Tilia tomentosa
Published in Plants (Basel) (01-01-2022)“…Concentrated bud macerates (CBMs) are obtained from meristematic tissues such as buds and young shoots by maceration in a solvent composed of glycerin, water…”
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8
Structure–activity relationship of natural and synthetic coumarins inhibiting the multidrug transporter P-glycoprotein
Published in Bioorganic & medicinal chemistry (15-10-2006)“…The substitution of the basic structure of coumarin, by phenyl group on position C 4 and α-(hydroxyisopropyl)dihydrofuran moiety on position C 5–C 6 or C 7–C…”
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9
Paradoxical effects of polyphenolic compounds from Clusiaceae on angiogenesis
Published in Biochemical pharmacology (15-02-2012)“…Among six tested polyphenolic compounds from Clusiaceae, the two endothelium-dependent vasodilatators isocalolongic acid (IA) and 2-deprenylrheediaxanthone…”
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10
Breast cancer resistance protein (BCRP/ABCG2): New inhibitors and QSAR studies by a 3D linear solvation energy approach
Published in European journal of pharmaceutical sciences (12-08-2009)“…A series of compounds derived from naturally occurring flavonoids and synthetic analogs have been evaluated on cell lines overexpressing the wild-type breast…”
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11
Cytotoxic coumarins from Calophyllum dispar
Published in Phytochemistry (Oxford) (01-10-2001)“…Six coumarins have been isolated from the fruits and the stem bark of Calophyllum dispar (Clusiaceae). The structures of these minor components were…”
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12
An accurate, cost-effective and simple colorimetric method for the quantification of total triterpenoid and steroidal saponins from plant materials
Published in Food chemistry (30-07-2022)“…•Universal colorimetric method for total quantification of saponins.•Quantification using only water-bath and spectrophotometer.•Bypassing all the interfering…”
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13
Fine characterization and microbiota assessment as keys to understanding the positive effect of standardized natural citrus extract on broiler chickens
Published in Journal of animal science (03-01-2023)“…Abstract The objective of this study was to investigate the effect and composition of a standardized natural citrus extract (SNCE) on both broiler chickens’…”
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14
Development of a quantification method for routine analysis of glucosinolates and camalexin in brassicaceous small-sized samples by simultaneous extraction prior to liquid chromatography determination
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-08-2022)“…Glucosinolates and camalexin are secondary metabolites that, as phytoanticipins and phytoalexins, play a crucial role in plant defence. The present work…”
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15
Matrix free laser desorption ionization assisted by 13C NMR dereplication: A complementary approach to LC-MS2 based chemometrics
Published in Talanta (Oxford) (01-02-2023)“…The identification of bioactive constituents from complex mixtures of Natural Products (NPs) is an important field of applied chemometrics. It requires the…”
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16
Development of a quantification method for routine analysis of glucosinolates and camalexin in brassicaceous small-sized samples by simultaneous extraction prior to liquid chromatography determination
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-08-2022)“…Glucosinolates and camalexin are secondary metabolites that, as phytoanticipins and phytoalexins, play a crucial role in plant defence. The present work…”
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17
Xanthone Inhibitors of Unfolded Protein Response Isolated from Calophyllum caledonicum
Published in Journal of natural products (Washington, D.C.) (13-06-2024)Get full text
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18
Antiangiogenic Tocotrienol Derivatives from Garcinia amplexicaulis
Published in Journal of natural products (Washington, D.C.) (27-12-2013)“…Phytochemical investigation of a dichloromethane extract from Garcinia amplexicaulis stem bark led to the isolation of four new tocotrienols (1–4); two known…”
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Xanthone Inhibitors of Unfolded Protein Response Isolated from Calophyllum caledonicum
Published in Journal of natural products (Washington, D.C.) (28-06-2024)“…The unfolded protein response (UPR) is a key component of fungal virulence. The prenylated xanthone γ-mangostin isolated from Garcinia mangostana (Clusiaceae)…”
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20
Bithiophenic MALDI matrices as valuable leads for the selective detection of alkaloids
Published in Analytical and bioanalytical chemistry (01-11-2017)“…Alkaloids represent a group of biologically most interesting compounds commonly used in modern medicines but also known for exhibiting severe toxic effects…”
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