Search Results - "GUIDUCCI, SERENA"
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Endothelial-to-mesenchymal transition contributes to endothelial dysfunction and dermal fibrosis in systemic sclerosis
Published in Annals of the rheumatic diseases (01-05-2017)“…Systemic sclerosis (SSc) features multiorgan fibrosis orchestrated predominantly by activated myofibroblasts. Endothelial-to-mesenchymal transition (EndoMT) is…”
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2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative
Published in Annals of the rheumatic diseases (01-11-2013)“…The 1980 American College of Rheumatology (ACR) classification criteria for systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc…”
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3
COVID-19 and rheumatic autoimmune systemic diseases: report of a large Italian patients series
Published in Clinical rheumatology (01-11-2020)“…Introduction Covid-19 infection poses a serious challenge for immune-compromised patients with inflammatory autoimmune systemic diseases. We investigated the…”
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AstraZeneca (AZD1222) COVID‐19 vaccine‐associated adverse drug event: A case report
Published in Journal of medical virology (01-10-2021)Get full text
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Lung ultrasound for the screening of interstitial lung disease in very early systemic sclerosis
Published in Annals of the rheumatic diseases (01-03-2013)“…A high percentage of patients with systemic sclerosis (SSc) develop interstitial lung disease (ILD) during the course of the disease. Promising data have…”
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The Role of Adipokines between Genders in the Pathogenesis of Osteoarthritis
Published in International journal of molecular sciences (01-10-2024)“…Osteoarthritis (OA) is a chronic, progressive, degenerative joint disease characterized by joint pain, stiffness, and limited movement. It presents significant…”
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Vascular Leaking, a Pivotal and Early Pathogenetic Event in Systemic Sclerosis: Should the Door Be Closed?
Published in Frontiers in immunology (07-09-2018)“…The early phase of systemic sclerosis (SSc) presents edema as one of the main features: this is clinically evident in the digital swelling (puffy fingers) as…”
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Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma?
Published in Annals of the rheumatic diseases (01-09-2014)“…Urokinase-type plasminogen activator receptor (uPAR) is a key component of the fibrinolytic system involved in extracellular matrix remodelling and…”
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Angiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium
Published in Scientific reports (16-10-2017)“…Despite increasing evidence suggesting that angiotensin II type 2 receptor (AT2R) may regulate tissue inflammation, no study has yet analyzed its possible…”
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The crowded crossroad to angiogenesis in systemic sclerosis: where is the key to the problem?
Published in Arthritis research & therapy (05-02-2016)“…In systemic sclerosis (SSc), peripheral vasculopathy is characterized by a progressive and irreversible loss of capillaries following endothelial cell injury,…”
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Interstitial lung disease in systemic sclerosis: where do we stand?
Published in European respiratory review (01-09-2015)“…Interstitial lung disease (ILD) is common in systemic sclerosis (SSc) patients and despite recent advances in the treatment is, at present, the major cause of…”
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Evidence for progressive reduction and loss of telocytes in the dermal cellular network of systemic sclerosis
Published in Journal of cellular and molecular medicine (01-04-2013)“…Telocytes, a peculiar type of stromal cells, have been recently identified in a variety of tissues and organs, including human skin. Systemic sclerosis (SSc,…”
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Mechanisms in the loss of capillaries in systemic sclerosis: angiogenesis versus vasculogenesis
Published in Journal of cellular and molecular medicine (01-06-2010)“…• Introduction ‐ Evidence for endothelial disease and loss of capillaries in SSc ‐ Angiogenesis and vasculogenesis • Mechanisms and biomarkers of…”
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Angiogenic T cell expansion correlates with severity of peripheral vascular damage in systemic sclerosis
Published in PloS one (10-08-2017)“…The mechanisms underlying endothelial cell injury and defective vascular repair in systemic sclerosis (SSc) remain unclear. Since the recently discovered…”
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Second-line biologic therapy optimization in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis
Published in Seminars in arthritis and rheumatism (01-10-2017)“…Abstract Objective The Italian board for the TAilored BIOlogic therapy (ITABIO) reviewed the most consistent literature to indicate the best strategy for the…”
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Early Detection of Cardiac Involvement in Systemic Sclerosis
Published in JACC. Cardiovascular imaging (01-05-2019)Get full text
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The "myth" of loss of angiogenesis in systemic sclerosis: a pivotal early pathogenetic process or just a late unavoidable event?
Published in Arthritis research & therapy (06-07-2017)“…Systemic sclerosis is considered a disease dominated by a "loss of angiogenesis", although in its early phases evidence indicates a disturbed angiogenic…”
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Decreased expression of neuropilin-1 as a novel key factor contributing to peripheral microvasculopathy and defective angiogenesis in systemic sclerosis
Published in Annals of the rheumatic diseases (01-08-2016)“…In systemic sclerosis (SSc), vascular involvement is characterised by vascular endothelial growth factor (VEGF)-A/VEGF receptor (VEGFR) system disturbances…”
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The systemic sclerosis patient in the COVID-19 era: the challenging crossroad between immunosuppression, differential diagnosis and long-term psychological distress
Published in Clinical rheumatology (01-07-2020)“…COVID-19 is a world health emergency which may inevitably affect the management of a complex autoimmune disease such as systemic sclerosis (SSc). Several SSc…”
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The positive side of the coin: Sars-Cov-2 pandemic has taught us how much Telemedicine is useful as standard of care procedure in real life
Published in Clinical rheumatology (01-02-2022)“…Patients and health workers were at high risk of infection during the Sars-Cov-2 pandemic lockdown. For this reason, other medical and clinical approaches such…”
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