Search Results - "GUENTHER, Brian D"

Ecto-5'-nucleotidase: a candidate virulence factor in Streptococcus sanguinis experimental endocarditis by Fan, Jingyuan, Zhang, Yongshu, Chuang-Smith, Olivia N, Frank, Kristi L, Guenther, Brian D, Kern, Marissa, Schlievert, Patrick M, Herzberg, Mark C

“…Streptococcus sanguinis is the most common cause of infective endocarditis (IE). Since the molecular basis of virulence of this oral commensal bacterium…”
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Calprotectin S100A9 Calcium-binding Loops I and II Are Essential for Keratinocyte Resistance to Bacterial Invasion by Champaiboon, Chantrakorn, Sappington, Kaia J., Guenther, Brian D., Ross, Karen F., Herzberg, Mark C.

“…Epithelial cells expressing calprotectin, a heterodimer of S100A8 and S100A9 proteins, are more resistant to bacterial invasion. To determine structural motifs…”
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Structural Perturbations in the Ala → Val Polymorphism of Methylenetetrahydrofolate Reductase:  How Binding of Folates May Protect against Inactivation by Pejchal, Robert, Campbell, Elizabeth, Guenther, Brian D, Lennon, Brett W, Matthews, Rowena G, Ludwig, Martha L

“…In human methylenetetrahydrofolate reductase (MTHFR) the Ala222Val (677C→T) polymorphism encodes a heat-labile gene product that is associated with elevated…”
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The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia by Guenther, Brian D, Ludwig, Martha L, Matthews, Rowena G, Rozen, Rima, Tran, Pamela, Sheppard, Christal A

“…Elevated plasma homocysteine levels are associated with increased risk for cardiovascular disease and neural tube defects in humans. Folate treatment decreases…”
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The structure of the TOG-like domain of Drosophila melanogaster Mast/Orbit by De la Mora-Rey, Teresa, Guenther, Brian D., Finzel, Barry C.

“…Mast/Orbit is a nonmotor microtubule‐associated protein (MAP) present in Drosophila melanogaster that reportedly binds microtubules at the plus end and is…”
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beta-Tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells by Gökmen-Polar, Yesim, Escuin, Daniel, Walls, Chad D, Soule, Sharon E, Wang, Yuefang, Sanders, Kerry L, Lavallee, Theresa M, Wang, Mu, Guenther, Brian D, Giannakakou, Paraskevi, Sledge, Jr, George W

“…2-Methoxyestradiol is an estradiol metabolite with significant antiproliferative and antiangiogenic activity independent of estrogen receptor status. To…”
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B-tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells by GÖKMEN-POLAR, Yesim, ESCUIN, Daniel, SLEDGE, George W, WALLS, Chad D, SOULE, Sharon E, YUEFANG WANG, SANDERS, Kerry L, LAVALLEE, Theresa M, MU WANG, GUENTHER, Brian D, GIANNAKAKOU, Paraskevi

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Preliminary crystallographic analysis of trypanothione reductase from Crithidia fasciculata by Kuriyan, J, Wong, L, Guenther, B D, Murgolo, N J, Cerami, A, Henderson, G B

“…Trypanothione reductase, a flavoprotein disulfide reductase specific to trypanosomatid parasites, has been crystallized by vapor diffusion of a protein…”
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