Search Results - "GUANGRONG LU"
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1
A Ratiometric Fluorescent Sensor Based on Chelation-Enhanced Fluorescence of Carbon Dots for Zinc Ion Detection
Published in Molecules (Basel, Switzerland) (28-11-2023)“…Zinc ion, one of the most important transition metal ions in living organisms, plays a crucial role in the homeostasis of the organism. The disorder of zinc is…”
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2
Impact of smoking on the risk of pancreatitis: a systematic review and meta-analysis
Published in PloS one (16-04-2015)“…Cigarette smoking may increase the risk of developing pancreatic cancer, although its impact on pancreatitis has only been discerned in recent years. However,…”
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3
Drug Screening of Human GBM Spheroids in Brain Cancer Chip
Published in Scientific reports (18-10-2018)“…Glioblastoma multiforme (GBM), an extremely invasive and high-grade (grade IV) glioma, is the most common and aggressive form of brain cancer. It has a poor…”
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4
A prognostic nomogram to predict survival in elderly patients with small-cell lung cancer: a large population-based cohort study and external validation
Published in BMC cancer (06-12-2022)“…Age is an independent prognostic factor for small cell lung cancer (SCLC). We aimed to construct a nomogram survival prediction for elderly SCLC patients based…”
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Triple-drug Therapy With Bevacizumab, Irinotecan, and Temozolomide Plus Tumor Treating Fields for Recurrent Glioblastoma: A Retrospective Study
Published in Frontiers in neurology (2019)“…Clinical studies treating pediatric and adult solid tumors, such as glioblastoma (GBM), with a triple-drug regimen of temozolomide (TMZ), bevacizumab (BEV),…”
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Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy
Published in Circulation (New York, N.Y.) (06-06-2006)“…Recent work has demonstrated the importance of chromatin remodeling, especially histone acetylation, in the control of gene expression in the heart. In cell…”
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Factors predicting the return of spontaneous circulation rate of cardiopulmonary resuscitation in China: Development and evaluation of predictive nomogram
Published in Heliyon (30-08-2024)“…This study aimed to construct and internally validate a probability of the return of spontaneous circulation (ROSC) rate nomogram in a Chinese population of…”
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Detection of the MYD88 p.L265P Mutation in the CSF of a Patient With Secondary Central Nervous System Lymphoma
Published in Frontiers in oncology (20-09-2018)“…Primary Central Nervous System Lymphoma (PCNSL) and Metastatic (or Secondary) Central Nervous System Lymphoma (MCNSL) are rare central nervous system (CNS)…”
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9
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling
Published in Circulation (New York, N.Y.) (12-09-2006)“…Cellular hypertrophy requires coordinated regulation of progrowth and antigrowth mechanisms. In cultured neonatal cardiomyocytes, Foxo transcription factors…”
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10
Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors
Published in Acta neuropathologica communications (31-08-2018)“…Cancer cells have altered cellular metabolism. Mutations in genes associated with key metabolic pathways (e.g., isocitrate dehydrogenase 1 and 2, IDH1/IDH2)…”
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FGF/FGFR signaling pathway involved resistance in various cancer types
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12
Constriction of retinal arterioles to endothelin-1: requisite role of rho kinase independent of protein kinase C and L-type calcium channels
Published in Investigative ophthalmology & visual science (17-05-2012)“…Although endothelin-1 (ET-1) is a potent vasoconstrictor peptide implicated in several retinal pathologies, the underlying mechanism of vasoconstriction is…”
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13
Proteasome inhibitor Bortezomib induces cell-cycle arrest and apoptosis in cell lines derived from Ewing's sarcoma family of tumors and synergizes with TRAIL
Published in Cancer biology & therapy (01-04-2008)“…Bortezomib (VELCADE®), formerly known as PS-341, is a novel dipeptide boronic acid proteasome inhibitor with in vitro and in vivo anti-tumor activity…”
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14
Rac1 and RhoA differentially regulate angiotensinogen gene expression in stretched cardiac fibroblasts
Published in Cardiovascular research (01-04-2011)“…Angiotensin II (Ang II) stimulates cardiac remodelling and fibrosis in the mechanically overloaded myocardium. Although Rho GTPases regulate several cellular…”
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15
Identification of m6A methyltransferase-related lncRNA signature for predicting immunotherapy and prognosis in patients with hepatocellular carcinoma
Published in Bioscience reports (25-06-2021)“…N6-methyladenosine (m6A) methyltransferase has been shown to be an oncogene in a variety of cancers. Nevertheless, the relationship between the long non-coding…”
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16
Analysis of SEMA3B methylation and expression patterns in gastric cancer tissue and cell lines
Published in Oncology reports (01-03-2014)“…The family of semaphorins has been demonstrated to possess tumor suppressor activity, in which semaphorin 3B (SEMA3B) is differentially expressed in several…”
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Integrins: novel therapeutic targets for cardiovascular diseases
Published in Cardiovascular & hematological agents in medicinal chemistry (01-04-2007)“…Integrins are the principle mediators of molecular dialog between a cell and its extracellular matrix environment. The unique combinations of integrin subunits…”
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18
FGF/FGFR signaling pathway involved resistance in various cancer types
Published in Journal of Cancer (01-01-2020)“…Resistance becomes major clinical issue in cancer treatment, which strongly limits patients to benefit from oncotherapy. Growing evidences have been indicative…”
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Survival benefit of glioblastoma patients after FDA approval of temozolomide concomitant with radiation and bevacizumab: A population-based study
Published in Oncotarget (04-07-2017)“…Few population-based analyses have investigated survival change in glioblastoma multiforme (GBM) patients treated with concomitant radiotherapy-temozolomide…”
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Development of a Survival Nomogram for Esophageal Squamous Cell Carcinoma Patients: a Population-Based Analysis
Published in Journal of gastrointestinal cancer (01-03-2024)“…Purpose In this study, we developed a prognostic nomogram for esophageal squamous cell carcinoma (ESCC) patients. Methods Patients diagnosed with ESCC from the…”
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