Search Results - "GU, XIAOQIONG"
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MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma
Published in Cell death & disease (19-05-2021)“…MYCN amplification is tightly associated with the poor prognosis of pediatric neuroblastoma (NB). The regulation of NB cell death by MYCN represents an…”
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2
Making waves: Wastewater surveillance of SARS-CoV-2 for population-based health management
Published in Water research (Oxford) (01-10-2020)“…•Wastewater surveillance cheaper and less invasive than massive testing of individuals.•Useful early alert of viral circulation to prevent outbreaks and inform…”
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3
SARS-CoV-2 Titers in Wastewater Are Higher than Expected from Clinically Confirmed Cases
Published in mSystems (25-08-2020)“…Wastewater-based surveillance is a promising approach for proactive outbreak monitoring. SARS-CoV-2 is shed in stool early in the clinical course and infects a…”
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4
Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups
Published in Nature communications (03-02-2021)“…Systemic lupus erythematosus (SLE), a worldwide autoimmune disease with high heritability, shows differences in prevalence, severity and age of onset among…”
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Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways
Published in Cell (14-11-2019)“…Pediatric-onset colitis and inflammatory bowel disease (IBD) have significant effects on the growth of infants and children, but the etiopathogenesis…”
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6
IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia
Published in Mucosal immunology (01-09-2020)“…Community-acquired pneumonia (CAP) contributes substantially to morbidity and mortality in children under the age of 5 years. In examining bronchoalveolar…”
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7
High levels of pigment epithelium-derived factor in diabetes impair wound healing through suppression of Wnt signaling
Published in Diabetes (New York, N.Y.) (01-04-2015)“…Diabetic foot ulcer (DFU) caused by impaired wound healing is a common vascular complication of diabetes. The current study revealed that plasma levels of…”
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8
Metagenomic and Resistome Analysis of a Full-Scale Municipal Wastewater Treatment Plant in Singapore Containing Membrane Bioreactors
Published in Frontiers in microbiology (18-02-2019)“…Reclaimed water provides a water supply alternative to address problems of scarcity in urbanized cities with high living densities and limited natural water…”
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9
Contextualizing Wastewater-Based surveillance in the COVID-19 vaccination era
Published in Environment international (01-01-2023)“…[Display omitted] •Based on historical reports, shedding of vaccine-derived genetic materials was only detected with replication-competent vaccines.•None of…”
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10
Epstein–Barr virus-encoded microRNA BART22 serves as novel biomarkers and drives malignant transformation of nasopharyngeal carcinoma
Published in Cell death & disease (30-07-2022)“…Nasopharyngeal carcinoma (NPC) is an epithelial malignancy ubiquitously associated with Epstein–Barr virus (EBV). EBV generates various viral microRNAs…”
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11
Occurrence of microbial indicators, pathogenic bacteria and viruses in tropical surface waters subject to contrasting land use
Published in Water research (Oxford) (01-03-2019)“…Fecal indicator bacteria, such as Escherichia coli (E.coli) and Enterococcus, have been widely used to indicate the presence of pathogens. However, the…”
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12
Geospatial distribution of viromes in tropical freshwater ecosystems
Published in Water research (Oxford) (15-06-2018)“…This study seeks to understand the general distribution of virome abundance and diversity in tropical freshwater ecosystems in Singapore and the geospatial…”
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13
Association of living environmental and occupational factors with semen quality in chinese men: a cross-sectional study
Published in Scientific reports (21-09-2023)“…Sperm quality can be easily influenced by living environmental and occupational factors. This study aimed to discover potential semen quality related living…”
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14
KRT6A Promotes Lung Cancer Cell Growth and Invasion Through MYC-Regulated Pentose Phosphate Pathway
Published in Frontiers in cell and developmental biology (21-06-2021)“…Keratin 6A (KRT6A) belongs to the keratin protein family which is a critical component of cytoskeleton in mammalian cells. Although KRT6A upregulation in…”
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15
Interleukin-33 Promotes Cell Survival via p38 MAPK-Mediated Interleukin-6 Gene Expression and Release in Pediatric AML
Published in Frontiers in immunology (26-11-2020)“…Acute myeloid leukemia (AML) is a fatal disease characterized by the accumulation of immature myeloid blasts in the bone marrow (BM). Cytokine provide signals…”
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16
Occurrence of Traditional and Alternative Fecal Indicators in Tropical Urban Environments under Different Land Use Patterns
Published in Applied and environmental microbiology (15-07-2018)“…This study evaluated the geospatial distribution of fecal indicator bacteria (FIB) (i.e., , spp.) and the alternative fecal indicator pepper mild mottle virus…”
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17
The lncRNA MALAT1 rs619586 G Variant Confers Decreased Susceptibility to Recurrent Miscarriage
Published in Frontiers in physiology (09-04-2019)“…Cardiovascula disease and recurrent miscarriage have shared risk factors, and some cardiovascular disease-related candidate genes have been confirmed to be…”
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Upregulation of PEDF Predicts a Poor Prognosis and Promotes Esophageal Squamous Cell Carcinoma Progression by Modulating the MAPK/ERK Signaling Pathway
Published in Frontiers in oncology (26-02-2021)“…Invasion and metastasis represent the primary causes of therapeutic failure in patients diagnosed with esophageal squamous cell carcinoma (ESCC). The lack of…”
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19
Homozygous of MRP4 Gene rs1751034 C Allele Is Related to Increased Risk of Intravenous Immunoglobulin Resistance in Kawasaki Disease
Published in Frontiers in genetics (15-03-2021)“…Kawasaki disease (KD) is a systemic vasculitis in childhood, which mainly causes damage to coronary arteries, and intravenous immunoglobulin (IVIG) is the…”
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The IL-1B Gene Polymorphisms rs16944 and rs1143627 Contribute to an Increased Risk of Coronary Artery Lesions in Southern Chinese Children with Kawasaki Disease
Published in Journal of immunology research (01-01-2019)“…Background. Kawasaki disease (KD) is a systemic form of self-limited vasculitis in children less than five years old, and the main complication is coronary…”
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