Search Results - "GSELL, W"

Functional assessment of strains around a full-thickness and critical sized articular cartilage defect under compressive loading using MRI by Zevenbergen, L., Gsell, W., Chan, D.D., Vander Sloten, J., Himmelreich, U., Neu, C.P., Jonkers, I.

“…The objective of this study was to evaluate the effect of full-thickness chondral defects on intratissue deformation patterns and matrix constituents in an…”
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Cartilage-on-cartilage contact: effect of compressive loading on tissue deformations and structural integrity of bovine articular cartilage by Zevenbergen, L., Gsell, W., Cai, L., Chan, D.D., Famaey, N., Vander Sloten, J., Himmelreich, U., Neu, C.P., Jonkers, I.

“…This study aims to characterize the deformations in articular cartilage under compressive loading and link these to changes in the extracellular matrix…”
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A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome by Ahuja, K, Vandenabeele, M, Nami, F, Lefevere, E, Van Hoecke, J, Bergmans, S, Claes, M, Vervliet, T, Neyrinck, K, Burg, T, De Herdt, D, Bhaskar, P, Zhu, Y, Looser, Z J, Loncke, J, Gsell, W, Plaas, M, Agostinis, P, Swinnen, J V, Van Den Bosch, L, Bultynck, G, Saab, A S, Wolfs, E, Chai, Y C, Himmelreich, U, Verfaillie, C, Moons, L, De Groef, L

“…Wolfram syndrome (WS) is a rare childhood disease characterized by diabetes mellitus, diabetes insipidus, blindness, deafness, neurodegeneration and eventually…”
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Lasting effects of chronic fluoxetine treatment on the late developing rat brain: Age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI by Klomp, A., Tremoleda, J.L., Wylezinska, M., Nederveen, A.J., Feenstra, M., Gsell, W., Reneman, L.

“…With the growing prevalence of psychotropic drug prescriptions among children and adolescents, the need for studies on lasting effects of drug exposure on the…”
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Biocompatible magnetic gelatin nanoparticles with enhanced MRI contrast performance prepared by single-step desolvation method by Teijeiro-Valiño, C, González Gómez, M A, Yáñez, S, García Acevedo, P, Arnosa Prieto, A, Belderbos, S, Gsell, W, Himmelreich, U, Piñeiro, Y, Rivas, J

“…Abstract Magnetic nanoparticles are versatile materials that have boosted the development of different biomedical applications, being superparamagnetic…”
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Longitudinal predictive analysis of vulnerable plaques in a mouse model of atherosclerosis by Mehta, V.V, Pedrigi, R.M, Bovens, S.M, Tremoleda, J.L, Gsell, W, Krams, R

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Increased brain levels of 4-hydroxy-2-nonenal glutathione conjugates in severe Alzheimer's disease by Völkel, Wolfgang, Sicilia, Tina, Pähler, Axel, Gsell, W., Tatschner, Thomas, Jellinger, Kurt, Leblhuber, Friedrich, Riederer, Peter, Lutz, Werner K., Götz, Mario E.

“…In the last decade an important role for the progression of neuronal cell death in Alzheimer's disease (AD) has been ascribed to oxidative stress…”
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Roux-en-Y Gastric Bypass in Mice—Surgical Technique and Characterisation by Seyfried, F., Lannoo, M., Gsell, W., Tremoleda, J. L., Bueter, M., Olbers, T., Jurowich, C., Germer, C.-T., le Roux, C. W.

“…Background A reproducible Roux-en-Y gastric bypass (RYGB) model in mice is needed to study the physiological alterations after surgery. Methods Male C57BL6…”
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P.1.i.016 Amphetamine pretreatment alters the response to a methylphenidate challenge: a pharmacological magnetic resonance imaging study by Schrantee, A, Tremoleda, J.L, Wylezinska-Arridge, M, Gsell, W, Reneman, L

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Enhancement of central nervous system pathology in early simian immunodeficiency virus infection by dopaminergic drugs by CZUB, S, KOUTSILIERI, E, GOSZTONYI, G, RIEDERER, P, TER MEULEN, V, SOPPER, S, CZUB, M, STAHL-HENNIG, C, MÜLLER, J. G, PEDERSEN, V, GSELL, W, HEENEY, J. L, GERLACH, M

“…Human immunodeficiency virus infection (HIV) at late stages of the disease is accompanied by neurological complications, including motor, behavioral and…”
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Therapeutic brain concentration of the NMDA receptor antagonist amantadine by Kornhuber, J., Quack, G., Danysz, W., Jellinger, K., Danielczyk, W., Gsell, W., Riederer, P.

“…Amantadine (1-amino-adamantane) is clinically used for the management of Parkinson's disease and drug-induced extrapyramidal symptoms. It has previously been…”
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Clec4e deletion in cardiac resident cells leads to smaller infarct size and better cardiac remodeling following myocardial ischemia-reperfusion injury by Algoet, M, Oosterlinck, W, Pusovnik, M, Himmelreich, U, Gsell, W, Veltman, D, Gillijns, H, Caluwe, E, Blazejczyk, K, Janssens, S

“…Abstract Introduction Clec4e-signalling in cardiac resident cells and circulating immune cells stimulates recruitment of proinflammatory leukocytes to…”
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(r)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in Alzheimer dementia by Frölich, L, Götz, M E, Weinmüller, M, Youdim, M B H, Barth, N, Dirr, A, Gsell, W, Jellinger, K, Beckmann, H, Riederer, P

“…In dementia of Alzheimer type (DAT), cerebral glucose metabolism is reduced in vivo, and enzymes involved in glucose breakdown are impaired in post-mortem…”
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Brain aging phenomena in migrating sockeye salmon Oncorhynchus nerka nerka by Götz, M E, Malz, C R, Dirr, A, Blum, D, Gsell, W, Schmidt, S, Burger, R, Pohli, S, Riederer, P

“…Aging, a process occurring in all vertebrates, is closely related to a loss in physical and functional abilities. There is widespread interest in clarifying…”
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Chronic Alcohol Consumption and Cerebral Indices of Oxidative Stress: Is There a Link? by Götz, M. E., Janetzky, B., Pohli, S., Gottschalk, A., Gsell, W., Tatschner, T., Ransmayr, G., Leblhuber, F., Gerlach, M., Reichmann, H., Riederer, P., Böning, J.

“…Background: It is still difficult to define the biochemical mechanisms that cause alterations in neuronal function and plasticity and neuronal cell loss in the…”
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Free radicals in Alzheimer's disease by Retz, W, Gsell, W, Münch, G, Rösler, M, Riederer, P

“…Alzheimer's disease is a neurodegenerative disorder comprising multisystem atrophies probably caused by multifactorial processes. The disease is characterized…”
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Clec4e signalling influences left-ventricular functional recovery in a murine model of myocardial ischemia-reperfusion injury by Veltman, D, Gillijns, H, Caluwe, E, Wu, M, Vanhaverbeke, M, Gsell, W, Himmelreich, U, Sinnaeve, P, Janssens, S

“…Abstract Introduction The acute inflammatory response contributes substantially to functional recovery and remodelling of the left ventricle after acute…”
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Inhibition of [ 3H] α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid [AMPA] binding by the anticonvulsant valproate in clinically relevant concentrations: an autoradiographic investigation in human hippocampus by Künig, G, Niedermeyer, B, Deckert, J, Gsell, W, Ransmayr, G, Riederer, P

“…The interaction of the anticonvulsant valproate with AMPA glutamate receptors in human post mortem hippocampus was investigated. At concentrations of ≥100 μM…”
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Oxidative-stress associated parameters (lactoferrin, superoxide dismutases) in serum of patients with Alzheimer's disease by Thome, J., Gsell, W., Rösier, M., Kornhuber, J., Frölich, L., Hashimoto, E., Zielke, B., Wiesbeck, G.A., Riedcrer, P.

“…In this case/control study, serum levels of oxidative stress related parameters such as Fe-binding lactoferrin (LTF), Mn- and Zn.Cu-superoxide dismutase (SOD)…”
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Blood transferrin and ferritin in Alzheimer's disease by Fischer, P., Götz, M.E., Danielczyk, W., Gsell, W., Riederer, P.

“…In the present study we found a significant correlation between severity of dementia of Alzheimer's type (DAT) and both transferrin and ferritin serum levels…”
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