Search Results - "GRZYBOWSKA, K"

Molecular Dynamics and Physical Stability of Coamorphous Ezetimib and Indapamide Mixtures by Knapik, J, Wojnarowska, Z, Grzybowska, K, Jurkiewicz, K, Tajber, L, Paluch, M

“…Low physical stability is the main reason limiting the widespread use of amorphous pharmaceuticals. One approach to overcome this problem is to mix these drugs…”
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High pressure as a key factor to identify the conductivity mechanism in protic ionic liquids by Wojnarowska, Z, Wang, Y, Pionteck, J, Grzybowska, K, Sokolov, A P, Paluch, M

“…In this Letter we report the relation between ionic conductivity and structural relaxation in supercooled protic ionic liquids (PILs) under high pressure. The…”
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Stabilization of the Amorphous Ezetimibe Drug by Confining Its Dimension by Knapik, J, Wojnarowska, Z, Grzybowska, K, Jurkiewicz, K, Stankiewicz, A, Paluch, M

“…The purpose of this paper is to investigate the influence of nanoconfinement on the molecular mobility, as well as on the physical stability, of amorphous…”
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Molecular Dynamics and Physical Stability of Amorphous Anti-Inflammatory Drug: Celecoxib by Grzybowska, K, Paluch, M, Grzybowski, A, Wojnarowska, Z, Hawelek, L, Kolodziejczyk, K, Ngai, K. L

“…By using dielectric spectroscopy we analyzed the relation between molecular mobility and tendency of the amorphous celecoxib to recrystallize. We found that…”
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Anomalous electrical conductivity behavior at elevated pressure in the protic ionic liquid procainamide hydrochloride by Wojnarowska, Z, Roland, C M, Swiety-Pospiech, A, Grzybowska, K, Paluch, M

“…Using broadband dielectric spectroscopy, we investigated the effect of hydrostatic pressure on the conductivity relaxation time τ{σ} of the supercooled protic…”
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Broadband Dielectric Relaxation Study at Ambient and Elevated Pressure of Molecular Dynamics of Pharmaceutical: Indomethacin by Wojnarowska, Z, Adrjanowicz, K, Wlodarczyk, P, Kaminska, E, Kaminski, K, Grzybowska, K, Wrzalik, R, Paluch, M, Ngai, K. L

“…Broadband dielectric measurements on the pharmaceutical indomethacin (IMC) were performed at ambient and elevated pressure. Data on molecular dynamics…”
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Physical Stability of the Amorphous Anticholesterol Agent (Ezetimibe): The Role of Molecular Mobility by Knapik, J, Wojnarowska, Z, Grzybowska, K, Hawelek, L, Sawicki, W, Wlodarski, K, Markowski, J, Paluch, M

“…The purpose of this paper is to examine the role of molecular mobility in the recrystallization process from the amorphous state of the anticholesterol drug…”
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Molecular Factors Governing the Liquid and Glassy States Recrystallization of Celecoxib in Binary Mixtures with Excipients of Different Molecular Weights by Grzybowska, K, Chmiel, K, Knapik-Kowalczuk, J, Grzybowski, A, Jurkiewicz, K, Paluch, M

“…Transformation of poorly water-soluble crystalline pharmaceuticals to the amorphous form is one of the most promising strategies to improve their oral…”
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Relaxation Dynamics and Crystallization Study of Sildenafil in the Liquid and Glassy States by Kolodziejczyk, K, Paluch, M, Grzybowska, K, Grzybowski, A, Wojnarowska, Z, Hawelek, L, Ziolo, J. D

“…In this paper, the physical stability and molecular dynamics of amorphous sildenafil are investigated in both the liquid and glassy states. We have established…”
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Aromaticity effect on supramolecular aggregation. Aromatic vs. cyclic monohydroxy alcohols by Soszka, N., Hachuła, B., Tarnacka, M., Grelska, J., Jurkiewicz, K., Geppert-Rybczyńska, M., Wrzalik, R., Grzybowska, K., Pawlus, S., Paluch, M., Kamiński, K.

“…[Display omitted] •A comprehensive study on self-aggregation of monohydroxy alcohols (MAs).•Impact of phenyl and cyclohexyl ring on the aggregation of…”
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Molecular Dynamics and Physical Stability of Amorphous Nimesulide Drug and Its Binary Drug–Polymer Systems by Knapik, J, Wojnarowska, Z, Grzybowska, K, Tajber, L, Mesallati, H, Paluch, K. J, Paluch, M

“…In this article we study the effectiveness of three well-known polymers: inulin, Soluplus, and PVP in stabilizing the amorphous form of nimesulide (NMS) drug…”
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Molecular dynamics of itraconazole at ambient and high pressure by Tarnacka, M, Adrjanowicz, K, Kaminska, E, Kaminski, K, Grzybowska, K, Kolodziejczyk, K, Wlodarczyk, P, Hawelek, L, Garbacz, G, Kocot, A, Paluch, M

“…Comprehensive molecular dynamics studies of vitrified and cryogrounded itraconazole (Itr) were performed at ambient and elevated pressure. DSC measurements…”
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Isothermal Cold Crystallization Kinetics Study of Sildenafil by Kolodziejczyk, K, Grzybowska, K, Wojnarowska, Z, Dulski, M, Hawelek, L, Paluch, M

“…Isothermal cold crystallization of sildenafil, which is used as API of Viagra, was investigated by differential scanning calorimetry, optical microscopy, and…”
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Consequences of an Equation of State in the Thermodynamic Scaling Regime by Grzybowski, A, Paluch, M, Grzybowska, K

“…An equation of state following from the generalized Lennard-Jones potential has been successfully applied to describe isothermal volumetric data for several…”
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Role of entropy in the thermodynamic evolution of the time scale of molecular dynamics near the glass transition by Grzybowska, K, Grzybowski, A, Pawlus, S, Pionteck, J, Paluch, M

“…In this paper, we investigate how changes in the system entropy influence the characteristic time scale of the system molecular dynamics near the glass…”
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Density Scaling of Supercooled Simple Liquids Near the Glass Transition by Grzybowski, A, Haracz, S, Paluch, M, Grzybowska, K

“…In this work, we show that two competing equations of state, the first one derived from some effective approximation of intermolecular potential suspected to…”
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Molecular Dynamics, Physical Stability and Solubility Advantage from Amorphous Indapamide Drug by Wojnarowska, Z, Grzybowska, K, Hawelek, L, Dulski, M, Wrzalik, R, Gruszka, I, Paluch, M, Pienkowska, K, Sawicki, W, Bujak, P, Paluch, K. J, Tajber, L, Markowski, J

“…This study for the first time investigates physicochemical properties of amorphous indapamide drug (IND), which is a known diuretic agent commonly used in the…”
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The influence of amorphization methods on the apparent solubility and dissolution rate of tadalafil by Wlodarski, K., Sawicki, W., Paluch, K.J., Tajber, L., Grembecka, M., Hawelek, L., Wojnarowska, Z., Grzybowska, K., Talik, E., Paluch, M.

“…[Display omitted] This study for the first time investigates the solubility and dissolution rate of amorphous tadalafil (Td) – a poorly water soluble chemical…”
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Ionic liquids and their bases: Striking differences in the dynamic heterogeneity near the glass transition by Grzybowska, K., Grzybowski, A., Wojnarowska, Z., Knapik, J., Paluch, M.

“…Ionic liquids (ILs) constitute an active field of research due to their important applications. A challenge for these investigations is to explore properties…”
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Study of the Amorphous Glibenclamide Drug: Analysis of the Molecular Dynamics of Quenched and Cryomilled Material by Wojnarowska, Z, Grzybowska, K, Adrjanowicz, K, Kaminski, K, Paluch, M, Hawelek, L, Wrzalik, R, Dulski, M, Sawicki, W, Mazgalski, J, Tukalska, A, Bieg, T

“…Glibenclamide (GCM) is an oral hypoglycemic agent of the sulfonylurea group used in the treatment of non-insulin-dependent diabetes. Crystalline GCM is…”
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