Search Results - "GRZESIEK, S"

Solution NMR of proteins within polyacrylamide gels: diffusional properties and residual alignment by mechanical stress or embedding of oriented purple membranes by Sass, H J, Musco, G, Stahl, S J, Wingfield, P T, Grzesiek, S

“…The diffusive properties of biomacromolecules within the aqueous phase of polyacrylamide gels are described. High quality NMR spectra can be obtained under…”
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A DFT Study of the Interresidue Dependencies of Scalar J-Coupling and Magnetic Shielding in the Hydrogen-Bonding Regions of a DNA Triplex by Barfield, Michael, Dingley, Andrew J, Feigon, Juli, Grzesiek, Stephan

“…Scalar coupling constants and magnetic shieldings in the imino hydrogen-bonding region of Hoogsteen−Watson−Crick T·A-T and C+·G−C triplets have been calculated…”
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Direct identification of NH⋯N hydrogen bonds in non-canonical base pairs of RNA by NMR spectroscopy by Wöhnert, Jens, Dingley, Andrew J., Stoldt, Matthias, Görlach, Matthias, Grzesiek, Stephan, Brown, Larry R.

“…It is shown that the recently developed quantitative JNN HNN-COSY experiment can be used for the direct identification of hydrogen bonds in non-canonical base…”
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Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain by Barbato, G, Cicero, D.O., Cordier, F, Narjes, F, Gerlach, B, Sambucini, S, Grzesiek, S, Matassa, V.G., De Francesco, R., Bazzo, R

“…Few structures of viral serine proteases, those encoded by the Sindbis and Semliki Forest viruses, hepatitis C virus (HCV) and cytomegalovirus, have been…”
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Refined solution structure and backbone dynamics of HIV‐1 Nef by Grzesiek, Stephan, Bax, Ad, Hu, Jin‐Shan, Tjandra, Nico, Kaufman, Joshua, Palmer, Ira, Stahl, Stephen J., Wingfield, Paul T.

“…The tendency of HIV‐1 Nef to form aggregates in solution, particularly at pH values below 8, together with its large fraction of highly mobile residues…”
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An easy way to include weak alignment constraints into NMR structure calculations by Sass, H J, Musco, G, Stahl, S J, Wingfield, P T, Grzesiek, S

“…We have recently shown that an energy penalty for the incorporation of residual tensorial constraints into molecular structure calculations can be formulated…”
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Nuclear magnetic resonance as a quantitative tool to study interactions in biomacromolecules by Grzesiek, S., Allan, M., Cordier, F., Häussinger, D., Jensen, P., Kahmann, J., Meier, S., Sass, H. J.

“…High-resolution nuclear magnetic resonance (NMR) has emerged as one of the most versatile tools for the quantitative study of structure, kinetics, and…”
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Imatinib disassembles the regulatory core of Abelson kinase by binding to its ATP site and not by binding to its myristoyl pocket by Grzesiek, Stephan, Paladini, Johannes, Habazettl, Judith, Sonti, Rajesh

“…It was recently reported (Xie et al., 2022) that the Abelson tyrosine kinase (Abl) ATP-site inhibitor imatinib also binds to Abl's myristoyl binding pocket,…”
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The signal transducer gp130: Solution structure of the carboxy-terminal domain of the cytokine receptor homology region by KERNEBECK, THOMAS, PFLANZ, STEFAN, MÜLLER-NEWEN, GERHARD, KURAPKAT, GÜNTHER, SCHEEK, RUUD M., DIJKSTRA, KLAAS, HEINRICH, PETER C., WOLLMER, AXEL, GRZESIEK, STEPHAN, GRÖTZINGER, JOACHIM

“…The transmembrane glycoprotein gp130 is the common signal transducing receptor subunit of the interleukin-6-type cytokines. It is a member of the…”
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Insights into biomolecular hydrogen bonds from hydrogen bond scalar couplings by Grzesiek, Stephan, Cordier, Florence, Jaravine, Victor, Barfield, Michael

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Foldon, The Natural Trimerization Domain of T4 Fibritin, Dissociates into a Monomeric A-state Form containing a Stable β-Hairpin: Atomic Details of Trimer Dissociation and Local β-Hairpin Stability from Residual Dipolar Couplings by Meier, Sebastian, Güthe, Sarah, Kiefhaber, Thomas, Grzesiek, Stephan

“…The C-terminal domain of T4 fibritin (foldon) is obligatory for the formation of the fibritin trimer structure and can be used as an artificial trimerization…”
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The importance of not saturating H2O in protein NMR. Application to sensitivity enhancement and NOE measurements by GRZESIEK, S, BAX, A

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Identification of Slow Correlated Motions in Proteins Using Residual Dipolar and Hydrogen-Bond Scalar Couplings by Bouvignies, Guillaume, Bernadó, Pau, Meier, Sebastian, Cho, Kyuil, Grzesiek, Stephan, Brüschweiler, Rafael, Blackledge, Martin, Bax, Adriaan

“…Despite their importance for biological activity, slower molecular motions beyond the nanosecond range remain poorly understood. We have assembled an…”
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Dependency of delta pH-relaxation across vesicular membranes on the buffering power of bulk solutions and lipids by Grzesiek, S., Dencher, N.A.

“…The dependency of delta pH-relaxation kinetics across the membrane of sonicated small phospholipid vesicles on the concentration of internally entrapped buffer…”
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Methodological advances in protein NMR by Bax, Ad, Grzesiek, Stephan

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delta pH-induced fluorescence quenching of 9-aminoacridine in lipid vesicles is due to excimer formation at the membrane by Grzesiek, S., Otto, H., Dencher, N.A.

“…The fluorescence of 9-aminoacridine (9-AA) is quenched in vesicular suspensions containing negatively charged lipid headgroups (e.g., phosphatidylserine) upon…”
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Transmembrane location of retinal in bacteriorhodopsin by neutron diffraction by Hauss, T, Grzesiek, S, Otto, H, Westerhausen, J, Heyn, M. P

“…The transmembrane location of the chromophore of bacteriorhodopsin was obtained by neutron diffraction on oriented stacks of purple membranes. Two selectively…”
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Recognition of RANTES by Extracellular Parts of the CCR5 Receptor by Duma, Luminita, Häussinger, Daniel, Rogowski, Marco, Lusso, Paolo, Grzesiek, Stephan

“…The chemokine RANTES (regulated upon activation, normal T-cell expressed and secreted) is a natural ligand of CCR5, one of the major HIV-1 coreceptors. It is…”
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Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography by Häussinger, Daniel, Ahrens, Thomas, Aberle, Thomas, Engel, Jürgen, Stetefeld, Jörg, Grzesiek, Stephan

“…Cellular adhesion by classical cadherins depends critically on the exact proteolytic removal of their N‐terminal prosequences. In this combined solution NMR…”
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NMRPipe: a multidimensional spectral processing system based on UNIX pipes by Delaglio, F, Grzesiek, S, Vuister, G W, Zhu, G, Pfeifer, J, Bax, A

“…The NMRPipe system is a UNIX software environment of processing, graphics, and analysis tools designed to meet current routine and research-oriented…”
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