Search Results - "GRUTZMANN, Robert"

Nationwide In-hospital Mortality Following Pancreatic Surgery in Germany is Higher than Anticipated by Nimptsch, Ulrike, Krautz, Christian, Weber, Georg F, Mansky, Thomas, Grützmann, Robert

“…OBJECTIVE:We aimed to determine the unbiased mortality rates for pancreatic surgery procedures at the national level through a comprehensive analysis of every…”
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Precursor Lesions for Sporadic Pancreatic Cancer : PanIN, IPMN, and MCN by Distler, M., Aust, D., Weitz, Jürgen, Pilarsky, C., Grützmann, Robert

“…Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most…”
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A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis by Fjeld, Karianne, Weiss, Frank Ulrich, Lasher, Denise, Rosendahl, Jonas, Chen, Jian-Min, Johansson, Bente B, Kirsten, Holger, Ruffert, Claudia, Masson, Emmanuelle, Steine, Solrun J, Bugert, Peter, Cnop, Miriam, Grützmann, Robert, Mayerle, Julia, Mössner, Joachim, Ringdal, Monika, Schulz, Hans-Ulrich, Sendler, Matthias, Simon, Peter, Sztromwasser, Paweł, Torsvik, Janniche, Scholz, Markus, Tjora, Erling, Férec, Claude, Witt, Heiko, Lerch, Markus M, Njølstad, Pål R, Johansson, Stefan, Molven, Anders

“…Anders Molven and colleagues show that a recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. The…”
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Reduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis - A meta-analysis by Krautz, Christian, Maier, Sarah L., Brunner, Maximilian, Langheinrich, Melanie, Giamarellos-Bourboulis, Evangelos J., Gogos, Charalambos, Armaganidis, Apostolos, Kunath, Frank, Grützmann, Robert, Weber, Georg F.

“…B cell function and antibody production are crucial factors in host protection during inflammation. We aimed to synthesize the available evidence on the…”
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Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes by Winter, Christof, Kristiansen, Glen, Kersting, Stephan, Roy, Janine, Aust, Daniela, Knösel, Thomas, Rümmele, Petra, Jahnke, Beatrix, Hentrich, Vera, Rückert, Felix, Niedergethmann, Marco, Weichert, Wilko, Bahra, Marcus, Schlitt, Hans J, Settmacher, Utz, Friess, Helmut, Büchler, Markus, Saeger, Hans-Detlev, Schroeder, Michael, Pilarsky, Christian, Grützmann, Robert

“…Predicting the clinical outcome of cancer patients based on the expression of marker genes in their tumors has received increasing interest in the past decade…”
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Rapidly fatal SMARCA4-deficient undifferentiated sarcoma originating from hybrid hemosiderotic fibrolipomatous tumor/pleomorphic hyalinizing angiectatic tumor of the foot by Agaimy, Abbas, Meidenbauer, Norbert, Sukov, William R., Stoehr, Robert, Vieth, Michael, Roemer, Frank, Grützmann, Robert, Folpe, Andrew L.

“…Pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts and hemosiderotic fibrolipomatous tumor (HFLT) are two rare low-grade locally recurring…”
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RREB1::MRTFB fusion‐positive extra‐glossal mesenchymal neoplasms: A series of five cases expanding their anatomic distribution and highlighting significant morphological and phenotypic diversity by Agaimy, Abbas, Din, Nasir Ud, Dermawan, Josephine K., Haller, Florian, Melzer, Katja, Denz, Axel, Baumhoer, Daniel, Stoehr, Robert, Grützmann, Robert, Antonescu, Cristina R.

“…The RREB1::MRTFB (former RREB1::MKL2) fusion characterizes ectomesenchymal chondromyxoid tumors (EMCMT) of the tongue. Only five molecularly confirmed…”
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The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma by Pérez-Mancera, Pedro A., Rust, Alistair G., van der Weyden, Louise, Kristiansen, Glen, Li, Allen, Sarver, Aaron L., Silverstein, Kevin A. T., Grützmann, Robert, Aust, Daniela, Rümmele, Petra, Knösel, Thomas, Herd, Colin, Stemple, Derek L., Kettleborough, Ross, Brosnan, Jacqueline A., Li, Ang, Morgan, Richard, Knight, Spencer, Yu, Jun, Stegeman, Shane, Collier, Lara S., ten Hoeve, Jelle J., de Ridder, Jeroen, Klein, Alison P., Goggins, Michael, Hruban, Ralph H., Chang, David K., Biankin, Andrew V., Grimmond, Sean M., Wessels, Lodewyk F. A., Wood, Stephen A., Iacobuzio-Donahue, Christine A., Pilarsky, Christian, Largaespada, David A., Adams, David J., Tuveson, David A.

“…An in vivo transposon screen in a pancreatic cancer model identifies frequent inactivation of Usp9x ; deletion of Usp9x cooperates with Kras G12D to accelerate…”
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Tumor Infiltration with CD20 + CD73 + B Cells Correlates with Better Outcome in Colorectal Cancer by Hansen, Frederik J, Wu, Zhiyuan, David, Paul, Mittelstädt, Anke, Jacobsen, Anne, Podolska, Malgorzata J, Ubieta, Kenia, Brunner, Maximilian, Kouhestani, Dina, Swierzy, Izabela, Roßdeutsch, Lotta, Klösch, Bettina, Kutschick, Isabella, Merkel, Susanne, Denz, Axel, Weber, Klaus, Geppert, Carol, Grützmann, Robert, Bénard, Alan, Weber, Georg F

“…Immunotherapy has become increasingly important in the treatment of colorectal cancer (CRC). Currently, CD73, also known as ecto-5'-nucleotidase (NT5E), has…”
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Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis by Bermejo-Rodriguez, Camino, Araos Henríquez, Joaquín, Caligiuri, Giuseppina, Pinto Teles, Sara, Park, Youngkyu, Evans, Anthony, Barrera, Lawrence N, Neesse, Albrecht, Grützmann, Robert, Aust, Daniela, Rümmele, Petra, Knösel, Thomas, Narita, Masako, Narita, Masashi, Campbell, Fiona, Öhlund, Daniel, Pilarsky, Christian, Dow, Lukas E, Humbert, Patrick O, Biffi, Giulia, Tuveson, David A, Perez-Mancera, Pedro A

“…Perturbation of cell polarity is a hallmark of pancreatic ductal adenocarcinoma (PDAC) progression. Scribble (SCRIB) is a well-characterized polarity regulator…”
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In-hospital mortality and failure to rescue following hepatobiliary surgery in Germany - a nationwide analysis by Krautz, Christian, Gall, Christine, Gefeller, Olaf, Nimptsch, Ulrike, Mansky, Thomas, Brunner, Maximilian, Weber, Georg F, Grutzmann, Robert, Kersting, Stephan

“…Background Recent observational studies on volume-outcome associations in hepatobiliary surgery were not designed to account for the varying extent of…”
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Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer by Dreyer, Stephan B, Pinese, Mark, Jamieson, Nigel B, Scarlett, Christopher J, Colvin, Emily K, Pajic, Marina, Johns, Amber L, Humphris, Jeremy L, Wu, Jianmin, Cowley, Mark J, Chou, Angela, Nagrial, Adnan M, Chantrill, Lorraine, Chin, Venessa T, Jones, Marc D, Moran-Jones, Kim, Carter, Christopher Ross, Dickson, Euan J, Samra, Jaswinder S, Merrett, Neil D, Gill, Anthony J, Kench, James G, Duthie, Fraser, Miller, David K, Cooke, Susanna, Aust, Daniela, Knösel, Thomas, Rümmele, Petra, Grützmann, Robert, Pilarsky, Christian, Nguyen, Nam Q, Musgrove, Elizabeth A, Bailey, Peter J, McKay, Colin J, Biankin, Andrew V, Chang, David K

“…We aimed to define preoperative clinical and molecular characteristics that would allow better patient selection for operative resection. Although we use…”
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Radio(chemo)therapy in anaplastic thyroid cancer—high locoregional but low distant control rates—a monocentric analysis of a tertiary referral center by Schmied, Matthias, Lettmaier, Sebastian, Semrau, Sabine, Traxdorf, Maximilian, Mantsopoulos, Konstantinos, Mueller, Sarina K., Iro, Heinrich, Denz, Axel, Grützmann, Robert, Fietkau, Rainer, Haderlein, Marlen

“…Background Anaplastic thyroid cancer (ATC) is a lethal disease with highly aggressive disease progression. This study analyses the influence of…”
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Unusual Manifestation of Live Staphylococcus saprophyticus, Corynebacterium urinapleomorphum , and Helicobacter pylori in the Gallbladder with Cholecystitis by Backert, Steffen, Tegtmeyer, Nicole, Oyarzabal, Omar A, Osman, Dana, Rohde, Manfred, Grützmann, Robert, Vieth, Michael

“…Culture-independent studies have identified DNA of bacterial pathogens in the gallbladder under pathological conditions, yet reports on the isolation of…”
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The association of Health-Related Quality of Life and 1-year-survival in sarcoma patients—results of a Nationwide Observational Study (PROSa) by Eichler, Martin, Singer, Susanne, Hentschel, Leopold, Richter, Stephan, Hohenberger, Peter, Kasper, Bernd, Andreou, Dimosthenis, Pink, Daniel, Jakob, Jens, Grützmann, Robert, Fung, Stephen, Wardelmann, Eva, Arndt, Karin, Heidt, Vitali, Bonilla, Sergio Armando Zapata, Gaidzik, Verena I., Jambor, Helena K., Weitz, Jürgen, Schaser, Klaus-Dieter, Bornhäuser, Martin, Schmitt, Jochen, Schuler, Markus K.

“…Background Sarcomas are rare cancers of high heterogeneity. Health-Related Quality of Life (HRQoL) has been shown to be a prognostic factor for survival in…”
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The Health-Related Quality of Life of Sarcoma Patients and Survivors in Germany-Cross-Sectional Results of a Nationwide Observational Study (PROSa) by Eichler, Martin, Hentschel, Leopold, Richter, Stephan, Hohenberger, Peter, Kasper, Bernd, Andreou, Dimosthenis, Pink, Daniel, Jakob, Jens, Singer, Susanne, Grützmann, Robert, Fung, Stephen, Wardelmann, Eva, Arndt, Karin, Heidt, Vitali, Hofbauer, Christine, Fried, Marius, Gaidzik, Verena I, Verpoort, Karl, Ahrens, Marit, Weitz, Jürgen, Schaser, Klaus-Dieter, Bornhäuser, Martin, Schmitt, Jochen, Schuler, Markus K, The PROSa Study Group

“…Sarcomas are rare cancers with high heterogeneity in terms of type, location, and treatment. The health-related quality of life (HRQoL) of sarcoma patients has…”
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Chemoradiotherapy with and without deep regional hyperthermia for squamous cell carcinoma of the anus by Ott, Oliver J., Schmidt, Manfred, Semrau, Sabine, Strnad, Vratislav, Matzel, Klaus E., Schneider, Ignaz, Raptis, Dimitrios, Uter, Wolfgang, Grützmann, Robert, Fietkau, Rainer

“…Purpose To compare results after chemoradiotherapy with and without deep regional hyperthermia in patients with anal cancer. Methods Between 2000 and 2015,…”
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Long-term tumor-free survival in a metastatic pancreatic carcinoma patient with FOLFIRINOX/Mitomycin, high-dose, fever inducing Viscum album extracts and subsequent R0 resection: A case report by Werthmann, Paul Georg, Inter, Pia, Welsch, Thilo, Sturm, Anne-Kathrin, Grützmann, Robert, Debus, Markus, Sterner, Martin-Günther, Kienle, Gunver Sophia

“…Metastatic pancreatic cancer has a dismal prognosis. Many patients seek integrative care as an add-on to their conventional cancer treatment. Viscum album…”
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Long-Term Follow-Up of Patients Receiving Neoadjuvant Treatment Modalties for Soft Tissue Sarcomas of the Extremities by Rauch, Miriam, Agaimy, Abbas, Semrau, Sabine, Willner, Alexander, Ott, Oliver, Fietkau, Rainer, Hohenberger, Werner, Croner, Roland S., Grützmann, Robert, Fechner, Katja, Vassos, Nikolaos

“…Background: Neoadjuvant treatment modalities in soft tissue sarcoma (STS) of the extremities have become more popular in recent years, but because of the…”
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Neoadjuvant Chemoradiation Combined with Regional Hyperthermia in Locally Advanced or Recurrent Rectal Cancer by Ott, Oliver J, Gani, Cihan, Lindner, Lars H, Schmidt, Manfred, Lamprecht, Ulf, Abdel-Rahman, Sultan, Hinke, Axel, Weissmann, Thomas, Hartmann, Arndt, Issels, Rolf D, Zips, Daniel, Belka, Claus, Grützmann, Robert, Fietkau, Rainer

“…To prospectively analyze feasibility and pathological complete response (pCR) rates of neoadjuvant chemoradiotherapy combined with regional hyperthermia (RHT)…”
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