Search Results - "GRUOL, D. L"

Physiological and pathological roles of interleukin-6 in the central nervous system by Gruol, D L, Nelson, T E

“…The cytokine interleukin-6 (IL-6) is an important mediator of inflammatory and immune responses in the periphery. IL-6 is produced in the periphery and acts…”
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Long-Term Potentiation in the Rat Hippocampus Is Reversibly Depressed by Chronic Intermittent Ethanol Exposure by Roberto, M, Nelson, T. E, Ur, C. L, Gruol, D. L

“…Department of Neuropharmacology and Alcohol Research Center, The Scripps Research Institute, La Jolla, California 92037 Roberto, M., T. E. Nelson, C. L. Ur,…”
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Viral Induction of Central Nervous System Innate Immune Responses by REMPEL, J. D, QUINA, L. A, BLAKELY-GONZALES, P. K, BUCHMEIER, M. J, GRUOL, D. L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The chemokine CCL2 modulates Ca2+ dynamics and electrophysiological properties of cultured cerebellar Purkinje neurons by Van Gassen, K. L. I., Netzeband, J. G., De Graan, P. N. E., Gruol, D. L.

“…The chemokine CCL2 is produced at high levels in the central nervous system (CNS) during infection, injury, neuroinflammation and other pathological…”
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Chronic intermittent ethanol exposure enhances NMDA-receptor-mediated synaptic responses and NMDA receptor expression in hippocampal CA1 region by Nelson, T.E., Ur, C.L., Gruol, D.L.

“…In previous studies, we found that chronic intermittent ethanol (CIE) treatment–a model of ethanol consumption in which animals are exposed to and withdrawn…”
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The transient depression of hippocampal CA1 LTP induced by chronic intermittent ethanol exposure is associated with an inhibition of the MAP kinase pathway by Roberto, M., Nelson, T. E., Ur, C. L., Brunelli, M., Sanna, P. P., Gruol, D. L.

“…Using electrophysiological and biochemical approaches, we investigated the effects of chronic, intermittent ethanol (CIE) treatment on activation of the…”
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Preconditioning rabbit cardiomyocytes: role of pH, vacuolar proton ATPase, and apoptosis by Gottlieb, R A, Gruol, D L, Zhu, J Y, Engler, R L

“…Ischemic preconditioning signals through protein kinase C (PKC) to protect against myocardial infarction. This protection is characterized by diminished…”
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Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6 by Nelson, T.E, Olde Engberink, A, Hernandez, R, Puro, A, Huitron-Resendiz, S, Hao, C, De Graan, P.N.E, Gruol, D.L

“…Highlight ► Transgenic mice with chronically elevated levels of IL-6 show enhanced excitatory synaptic transmission in the hippocampus…”
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Altered physiology of purkinje neurons in cerebellar slices from transgenic mice with chronic central nervous system expression of interleukin-6 by Nelson, T.E., Campbell, I.L., Gruol, D.L.

“…The cytokine interleukin-6 is produced at elevated levels within the central nervous system in a number of neurological diseases and has been proposed to…”
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The rate of wound healing is increased in psoriasis by Morhenn, V.B, Nelson, T.E, Gruol, D.L

“…Abstract Background Psoriasis shares many features with wound healing, a process that involves switching keratinocytes from growth to differentiation. Ca2+ is…”
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Ca2+ signaling pathways linked to glutamate receptor activation in the somatic and dendritic regions of cultured cerebellar purkinje neurons by Gruol, D L, Netzeband, J G, Parsons, K L

“…1. Ca2+ signaling elicited by ionotropic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate (iGluR) and metabotropic (mGluR) glutamate…”
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Chronic intermittent ethanol exposure alters CA1 synaptic transmission in rat hippocampal slices by Nelson, T.E, Ur, C.L, Gruol, D.L

“…We investigated the neuroadaptive changes in synaptic transmission in the CA1 region of the hippocampus as a result of chronic intermittent ethanol exposure…”
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Neurosteroid regulation of inhibitory synaptic transmission in the rat hippocampus in vitro by Meyer, J.H., Lee, S., Wittenberg, G.F., Randall, R.D., Gruol, D.L.

“…The effect of the neurosteroid dehydroepiandrosterone sulfate on inhibitory synaptic transmission was studied in area CA1 of the rat hippocampus using an in…”
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Neuroadaptive changes in cerebellar neurons induced by chronic exposure to IL-6 by Gruol, D.L, Puro, A, Hao, C, Blakely, P, Janneke, E, Vo, K

“…Abstract IL-6 is an important signaling molecule in the CNS. CNS neurons express IL-6 receptors and their signal transduction molecules, consistent with a role…”
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Contribution of L‐type channels to Ca 2+ regulation of neuronal properties in early developing Purkinje neurons by Gruol, D. L., Netzeband, J. G., Quina, L. A., Blakely‐Gonzalez, P. K.

“…Activity driven Ca 2+ signaling is an important regulator of neuronal development. Early developing Purkinje neurons (postnatal day 5-7) prior to the stage of…”
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Somatic Ca2+ signaling in cerebellar Purkinje neurons by Gruol, D.L., Netzeband, J.G., Nelson, T.E.

“…Activity‐driven Ca2+ signaling plays an important role in a number of neuronal functions, including neuronal growth, differentiation, and plasticity. Both…”
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Chronic alcohol reduces calcium signaling elicited by glutamate receptor stimulation in developing cerebellar neurons by Gruol, D.L., Parsons, K.L.

“…The effect of chronic alcohol (33 mM ethanol) on Ca 2+ signals elicited by glutamate receptor agonists (quisqualate and NMDA) was examined in developing…”
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Inhibition of astrocyte glutamate uptake by reactive oxygen species: role of antioxidant enzymes by Sorg, O, Horn, T F, Yu, N, Gruol, D L, Bloom, F E

“…The recent literature suggests that free radicals and reactive oxygen species may account for many pathologies, including those of the nervous system. The…”
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Morphological and physiological differentiation of Purkinje neurons in cultures of rat cerebellum by Gruol, DL, Franklin, CL

“…During ontogeny, vertebrate CNS neurons differentiate from relatively simple stem cells to complex units that express unique morphological and…”
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Ca2+ regulation of a large conductance K+ channel in cultured rat cerebellar Purkinje neurons by Jacquin, T. D., Gruol, D. L.

“…The calcium sensitivity of a large conductance voltage‐sensitive potassium channel found in cultured rat cerebellar Purkinje neurons was studied in membrane…”
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