Search Results - "GRUBHOFFER, Libor"

Novel targets and strategies to combat borreliosis by Strnad, Martin, Grubhoffer, Libor, Rego, Ryan O.M.

“…Lyme borreliosis is a bacterial infection that can be spread to humans by infected ticks and may severely affect many organs and tissues. Nearly four decades…”
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Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases by de la Fuente, José, Antunes, Sandra, Bonnet, Sarah, Cabezas-Cruz, Alejandro, Domingos, Ana G, Estrada-Peña, Agustín, Johnson, Nicholas, Kocan, Katherine M, Mansfield, Karen L, Nijhof, Ard M, Papa, Anna, Rudenko, Nataliia, Villar, Margarita, Alberdi, Pilar, Torina, Alessandra, Ayllón, Nieves, Vancova, Marie, Golovchenko, Maryna, Grubhoffer, Libor, Caracappa, Santo, Fooks, Anthony R, Gortazar, Christian, Rego, Ryan O M

“…Ticks and the pathogens they transmit constitute a growing burden for human and animal health worldwide. Vector competence is a component of vectorial capacity…”
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Ehrlichia minasensis sp. nov., isolated from the tick Rhipicephalus microplus by Cabezas-Cruz, Alejandro, Zweygarth, Erich, Vancová, Marie, Broniszewska, Marzena, Grubhoffer, Libor, Passos, Lygia Maria Friche, Ribeiro, Múcio Flávio Barbosa, Alberdi, Pilar, de la Fuente, José

“…Recently, we obtained a rickettsial isolate ( sp. UFMG-EV ) from the haemolymph of engorged tick females. On the basis of maximum-likelihood phylogenetic…”
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Prevalence of Borrelia miyamotoi in Ixodes ticks in Europe and the United States by Crowder, Chris D, Carolan, Heather E, Rounds, Megan A, Honig, Vaclav, Mothes, Benedikt, Haag, Heike, Nolte, Oliver, Luft, Ben J, Grubhoffer, Libor, Ecker, David J, Schutzer, Steven E, Eshoo, Mark W

“…Borrelia miyamotoi, a relapsing fever-related spirochete transmitted by Ixodes ticks, has been recently shown to be a human pathogen. To characterize the…”
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Comprehensive N-glycosylation mapping of envelope glycoprotein from tick-borne encephalitis virus grown in human and tick cells by Lattová, Erika, Straková, Petra, Pokorná-Formanová, Petra, Grubhoffer, Libor, Bell-Sakyi, Lesley, Zdráhal, Zbyněk, Palus, Martin, Ruzek, Daniel

“…Tick-borne encephalitis virus (TBEV) is the causative agent of severe human neuroinfections that most commonly occur after a tick bite. N -Glycosylation of the…”
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Genomic Confirmation of Borrelia garinii, United States by Rudenko, Natalie, Golovchenko, Maryna, Horak, Ales, Grubhoffer, Libor, Mongodin, Emmanuel F, Fraser, Claire M, Qiu, Weigang, Luft, Benjamin J, Morgan, Richard G, Casjens, Sherwood R, Schutzer, Steven E

“…Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the…”
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Catalogue of stage-specific transcripts in Ixodes ricinus and their potential functions during the tick life-cycle by Vechtova, Pavlina, Fussy, Zoltan, Cegan, Radim, Sterba, Jan, Erhart, Jan, Benes, Vladimir, Grubhoffer, Libor

“…The castor bean tick Ixodes ricinus is an important vector of several clinically important diseases, whose prevalence increases with accelerating global…”
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Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission by Rego, Ryan O M, Trentelman, Jos J A, Anguita, Juan, Nijhof, Ard M, Sprong, Hein, Klempa, Boris, Hajdusek, Ondrej, Tomás-Cortázar, Julen, Azagi, Tal, Strnad, Martin, Knorr, Sarah, Sima, Radek, Jalovecka, Marie, Fumačová Havlíková, Sabína, Ličková, Martina, Sláviková, Monika, Kopacek, Petr, Grubhoffer, Libor, Hovius, Joppe W

“…Hematophagous arthropods are responsible for the transmission of a variety of pathogens that cause disease in humans and animals. Ticks of the Ixodes ricinus…”
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Ultrastructural mapping of salivary gland innervation in the tick Ixodes ricinus by Vancová, Marie, Bílý, Tomáš, Nebesářová, Jana, Grubhoffer, Libor, Bonnet, Sarah, Park, Yoonseong, Šimo, Ladislav

“…The salivary gland of hard ticks is a highly innervated tissue where multiple intertwined axonal projections enter each individual acini. In the present study,…”
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Three-dimensional reconstruction of the feeding apparatus of the tick Ixodes ricinus (Acari: Ixodidae): a new insight into the mechanism of blood-feeding by Vancová, Marie, Bílý, Tomáš, Šimo, Ladislav, Touš, Jan, Horodyský, Petr, Růžek, Daniel, Novobilský, Adam, Salát, Jiří, Strnad, Martin, Sonenshine, Daniel E., Grubhoffer, Libor, Nebesářová, Jana

“…The different components of the mouthparts of hard ticks (Ixodidae) enable these parasites to penetrate host skin, secrete saliva, embed, and suck blood…”
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Knockdown of proteins involved in iron metabolism limits tick reproduction and development by Hajdusek, Ondrej, Sojka, Daniel, Kopacek, Petr, Buresova, Veronika, Franta, Zdenek, Sauman, Ivo, Winzerling, Joy, Grubhoffer, Libor

“…Ticks are among the most important vectors of a wide range of human and animal diseases. During blood feeding, ticks are exposed to an enormous amount of free…”
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Karyotype changes in long-term cultured tick cell lines by Kotsarenko, Kateryna, Vechtova, Pavlina, Lieskovska, Jaroslava, Füssy, Zoltán, Cabral-de-Mello, Diogo C., Rego, Ryan O. M., Alberdi, Pilar, Collins, Marisol, Bell-Sakyi, Lesley, Sterba, Jan, Grubhoffer, Libor

“…Tick cell lines are an easy-to-handle system for the study of viral and bacterial infections and other aspects of tick cellular processes. Tick cell cultures…”
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Induction and suppression of tick cell antiviral RNAi responses by tick-borne flaviviruses by Schnettler, Esther, Tykalová, Hana, Watson, Mick, Sharma, Mayuri, Sterken, Mark G, Obbard, Darren J, Lewis, Samuel H, McFarlane, Melanie, Bell-Sakyi, Lesley, Barry, Gerald, Weisheit, Sabine, Best, Sonja M, Kuhn, Richard J, Pijlman, Gorben P, Chase-Topping, Margo E, Gould, Ernest A, Grubhoffer, Libor, Fazakerley, John K, Kohl, Alain

“…Arboviruses are transmitted by distantly related arthropod vectors such as mosquitoes (class Insecta) and ticks (class Arachnida). RNA interference (RNAi) is…”
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Evolution of tertiary structure of viral RNA dependent polymerases by Černý, Jiří, Černá Bolfíková, Barbora, Valdés, James J, Grubhoffer, Libor, Růžek, Daniel

“…Viral RNA dependent polymerases (vRdPs) are present in all RNA viruses; unfortunately, their sequence similarity is too low for phylogenetic studies…”
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Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors by Selinger, Martin, Věchtová, Pavlína, Tykalová, Hana, Ošlejšková, Petra, Rumlová, Michaela, Štěrba, Ján, Grubhoffer, Libor

“…[Display omitted] Tick-borne encephalitis virus (TBEV), the most medically relevant tick-transmitted flavivirus in Eurasia, targets the host central nervous…”
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Tick-borne encephalitis virus inhibits rRNA synthesis and host protein production in human cells of neural origin by Selinger, Martin, Tykalová, Hana, Štěrba, Ján, Věchtová, Pavlína, Vavrušková, Zuzana, Lieskovská, Jaroslava, Kohl, Alain, Schnettler, Esther, Grubhoffer, Libor

“…Tick-borne encephalitis virus (TBEV), a member of the genus Flavivirus (Flaviviridae), is a causative agent of a severe neuroinfection. Recently, several…”
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Multiple Acquisitions of Pathogen-Derived Francisella Endosymbionts in Soft Ticks by Gerhart, Jonathan G, Auguste Dutcher, H, Brenner, Amanda E, Moses, Abraham S, Grubhoffer, Libor, Raghavan, Rahul

“…Abstract Bacterial endosymbionts of ticks are of interest due to their close evolutionary relationships with tick-vectored pathogens. For instance, whereas…”
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Tick-Borne Encephalitis Virus Adaptation in Different Host Environments and Existence of Quasispecies by Helmová, Renata, Hönig, Václav, Tykalová, Hana, Palus, Martin, Bell-Sakyi, Lesley, Grubhoffer, Libor

“…A highly virulent strain (Hypr) of tick-borne encephalitis virus (TBEV) was serially subcultured in the mammalian porcine kidney stable (PS) and tick…”
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Proteome Profiling of PMJ2-R and Primary Peritoneal Macrophages by Rusanov, Alexander L, Kozhin, Peter M, Tikhonova, Olga V, Zgoda, Victor G, Loginov, Dmitry S, Chlastáková, Adéla, Selinger, Martin, Sterba, Jan, Grubhoffer, Libor, Luzgina, Nataliya G

“…In vitro models are often used for studying macrophage functions, including the process of phagocytosis. The application of primary macrophages has limitations…”
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Characterization of ferritin 2 for the control of tick infestations by Hajdusek, Ondrej, Almazán, Consuelo, Loosova, Gabriela, Villar, Margarita, Canales, Mario, Grubhoffer, Libor, Kopacek, Petr, de la Fuente, José

“…Abstract Ixodes ricinus is one the most abundant tick species in Europe and these ticks transmit pathogens causing human and animal diseases. The cattle ticks,…”
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