Search Results - "GROSS, PATRICK"

Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation by Gross, Patrick, Sheets, Katie J., Warren, Noël A., Ghosh, Saptarshi, Varghese, Rebekah E., Wass (KWass), Katherine E., Kadimisetty, Karteek

“…PROTACs have emerged as a new class of drugs that can target the “undruggable” proteome by hijacking the ubiquitin proteasome system. Despite PROTACs’ success,…”
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Interval travel times for robust synchronization in city logistics vehicle routing by Groß, Patrick-Oliver, Ehmke, Jan Fabian, Mattfeld, Dirk Christian

“…•Complete information flow to consider travel time uncertainty in city logistics vehicle routing.•An innovative approach for robust routing in city…”
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Sodium Bicyclo[1.1.1]pentanesulfinate: A Bench‐Stable Precursor for Bicyclo[1.1.1]pentylsulfones and Bicyclo‐ [1.1.1]pentanesulfonamides by Bär, Robin M., Gross, Patrick J., Nieger, Martin, Bräse, Stefan

“…Herein, we present the synthesis of the bench‐stable sodium bicyclo[1.1.1]pentanesulfinate (BCP‐SO2Na) and its application in the synthesis of…”
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Blue skies in the making: Air quality action plans and urban imaginaries in London, Hong Kong, and San Francisco by Gross, Patrick Léon, Buchanan, Nicholas, Sané, Sabine

“…Air quality action plans (AQAPs) are emerging as a promising governance tool that cities employ in pursuit of clean air transitions. Representing a city’s…”
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Tandem Ubiquitin Binding Entities (TUBEs) as Tools to Explore Ubiquitin-Proteasome System and PROTAC Drug Discovery by Kadimisetty, Karteek, Sheets, Katie J, Gross, Patrick H, Zerr, Myra J, Ouazia, Dahmane

“…The ubiquitin proteasome system (UPS) is a complex pathway that involves multiple enzymes and culminates in the formation of a polyubiquitin chain on a target…”
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The Total Synthesis of (±)-Fumimycin by Gross, Patrick J., Bräse, Stefan

“…The antibiotic agent fumimycin has been synthesized for the first time. This natural product was found to inhibit the bacterial peptide deformylase and may…”
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Pyramiding rpg4 - and Rpg1 -Mediated Stem Rust Resistance in Barley Requires the Rrr1 Gene for Both to Function by Sharma Poudel, Roshan, Al-Hashel, Abdullah F, Gross, Thomas, Gross, Patrick, Brueggeman, Robert

“…Stem rust, caused by f. sp. ( ) is an economically important disease of wheat and barley. is the only resistance gene deployed in Midwestern US barley…”
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Characterization of genes required for both Rpg1 and rpg4-mediated wheat stem rust resistance in barley by Solanki, Shyam, Richards, Jonathan, Ameen, Gazala, Wang, Xue, Khan, Atiya, Ali, Harris, Stangel, Alex, Tamang, Prabin, Gross, Thomas, Gross, Patrick, Fetch, Thomas G, Brueggeman, Robert S

“…Puccinia graminis f. sp. tritici (Pgt) race TTKSK and its lineage pose a threat to barley production world-wide justifying the extensive efforts to identify,…”
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Impact of severe dry season on net ecosystem exchange in the Neotropical rainforest of French Guiana by BONAL, DAMIEN, BOSC, ALEXANDRE, PONTON, STÉPHANE, GORET, JEAN-YVES, BURBAN, BENOÎT, GROSS, PATRICK, BONNEFOND, JEAN-MARC, ELBERS, JAN, LONGDOZ, BERNARD, EPRON, DANIEL, GUEHL, JEAN-MARC, GRANIER, ANDRÉ

“…The lack of information on the ways seasonal drought modifies the CO₂ exchange between Neotropical rainforest ecosystems and the atmosphere and the resulting…”
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Genetic diversity of Aegilops L. species from Azerbaijan and Georgia using SSR markers by Abbasov, Mehraj, Brueggeman, Robert, Raupp, John, Akparov, Zeynal, Aminov, Naib, Bedoshvili, David, Gross, Thomas, Gross, Patrick, Babayeva, Sevda, Izzatullayeva, Vusala, Mammadova, Sevinj A., Hajiyev, Elchin, Rustamov, Khanbala, Gill, Bikram S.

“…Five microsatellite (SSR) markers were used to evaluate the genetic diversity of six Aegilops species from Azerbaijan and Georgia. A total of 39 alleles were…”
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Asymmetric total synthesis of (+)-fumimycin via 1,2-addition to ketimines by Gross, Patrick J, Furche, Filipp, Nieger, Martin, Bräse, Stefan

“…The first asymmetric total synthesis of fumimycin was accomplished. As a key step, a 1,2-addition of methyl Grignard reagents to ketimines with quinine as…”
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ARFI-prepared MRgHIFU in liver: Simultaneous mapping of ARFI-displacement and temperature elevation, using a fast GRE-EPI sequence by Auboiroux, Vincent, Viallon, Magalie, Roland, Joerg, Hyacinthe, Jean-Noël, Petrusca, Lorena, Morel, Denis R., Goget, Thomas, Terraz, Sylvain, Gross, Patrick, Becker, Christoph D., Salomir, Rares

“…MR acoustic radiation force imaging (ARFI) is an elegant adjunct to MR‐guided high intensity focused ultrasound for treatment planning and optimization,…”
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Ten years of fluxes and stand growth in a young beech forest at Hesse, North-eastern France by Granier, André, Bréda, Nathalie, Longdoz, Bernard, Gross, Patrick, Ngao, Jérôme

“…• Water and carbon fluxes, as measured by eddy covariance, climate, soil water content, leaf area index, tree biomass, biomass increment (BI), litter fall and…”
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Synthesis and Structural Characterization of Homo‐ and Heterometallic Li and Li/Ln Disiloxanediolate Complexes by Rausch, Janek, Liebing, Phil, Lorenz, Volker, Hrib, Cristian G., Ali, Asim, Groß, Patrick, Hilfert, Liane, Busse, Sabine, Edelmann, Frank T.

“…A series of new homo‐ and heterometallic lithium and lithium/lanthanide disiloxanediolate complexes were prepared and fully characterized. Three new adducts of…”
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Synthesis of Methoxyfumimycin with 1,2-Addition to Ketimines by Gross, Patrick J, Hartmann, Caroline E, Nieger, Martin, Bräse, Stefan

“…The synthesis of (±)-methoxyfumimycin, a potential new bacterial peptide deformylase (PDF) inhibitor, is reported. To generate the stereogenic fully…”
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Towards an asymmetric synthesis of the bacterial peptide deformylase (PDF) inhibitor fumimycin by Hartmann, Caroline E, Gross, Patrick J, Nieger, Martin, Bräse, Stefan

“…Studies towards the synthesis of the bacterial peptide deformylase (PDF) inhibitor fumimycin are reported. The synthetic approach features an organocatalytic…”
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A pilot study for clinical feasibility of the near-harmonic 2D referenceless PRFS thermometry in liver under free breathing using MR-guided LITT ablation data by Kickhefel, Antje, Rosenberg, Christian, Roland, Jörg, Viallon, Magalie, Gross, Patrick, Schick, Fritz, Hosten, Norbert, Salomir, Rares

“…The conventional implementations of proton resonance frequency shift (PRFS) magnetic resonance thermometry (MRT) require the subtraction of single or multiple…”
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Temperature effects on hydraulic conductance and water relations of Quercus robur L by Cochard, Hervé, Martin, Rodolphe, Gross, Patrick, Bogeat‐Triboulot, Marie Béatrice

“…The effects of temperature on root and shoot hydraulic conductances (gshoot and groot) were investigated for Quercus robur L. saplings. In a first experiment,…”
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Deep Vein Thrombosis in Amputee Patients by Arneja, Amarjit, MD, FRCPC, Alhashemi, Hashem, MD, FRCPC, Olafson, Tracey, RN, Gross, Patrick, BMR(PT)

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Fast growth involves high dependence on stored resources in seedlings of Mediterranean evergreen trees by Uscola, Mercedes, Villar-Salvador, Pedro, Gross, Patrick, Maillard, Pascale

“…The carbon (C) and nitrogen (N) needed for plant growth can come either from soil N and current photosynthesis or through remobilization of stored resources…”
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