Search Results - "GRIZZLE, W. E"

Factors that drive the increasing use of FFPE tissue in basic and translational cancer research by Gaffney, E F, Riegman, P H, Grizzle, W E, Watson, P H

“…The decision to use 10% neutral buffered formalin fixed, paraffin embedded (FFPE) archival pathology material may be dictated by the cancer research question…”
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A standard tissue as a control for histochemical and immunohistochemical staining by Otali, D, Fredenburgh, J, Oelschlager, D K, Grizzle, W E

“…The variable quality of histochemical and immunohistochemical staining of tissues may be attributed to pre-analytical and analytical variables. Both categories…”
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Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model by Bhardwaj, A, Singh, S, Srivastava, S K, Arora, S, Hyde, S J, Andrews, J, Grizzle, W E, Singh, A P

“…Background: Emergence of castration-resistance in prostate cancer (PCa) is invariably associated with aggressive and metastatic disease. Previously, we…”
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Special symposium: fixation and tissue processing models by Grizzle, W E

“…Abstract Fixation and processing of tissue to paraffin blocks permit thin (4-5 microm) sections of tissues to be cut. Tissues and their subcellular components…”
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Establishing a tumour bank: banking, informatics and ethics by QUALMAN, S. J, FRANCE, M, GRIZZLE, W. E, LIVOLSI, V. A, MOSKALUK, C. A, RAMIREZ, N. C, WASHINGTON, M. K

“…The six divisions of the Cooperative Human Tissue Network in the USA bank and distribute tens of thousands of tissue specimens to researchers annually. Major…”
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Preservation of immunorecognition by transferring cells from 10% neutral buffered formalin to 70% ethanol by Otali, D, He, Q, Stockard, C R, Grizzle, W E

“…Prolonged fixation of cells and tissues in 10% neutral buffered formalin (NBF) may decrease immunorecognition in some antigen-antibody pairs. Short fixation in…”
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MicroRNAs as potential clinical biomarkers: emerging approaches for their detection by Srivastava, S K, Bhardwaj, A, Leavesley, S J, Grizzle, W E, Singh, S, Singh, A P

“…MicroRNAs (miRNAs) have emerged as novel post-transcriptional regulators of gene expression. These short non-coding RNAs are involved in diverse biological…”
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The effect of isolated soy protein on plasma biomarkers in elderly men with elevated serum prostate specific antigen by Urban, D, Irwin, W, Kirk, M, Markiewicz, M A, Myers, R, Smith, M, Weiss, H, Grizzle, W E, Barnes, S

“…We performed a randomized double-blind crossover pilot study in elderly men with elevated prostate specific antigen (PSA) on the effects of the daily…”
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MicroRNA-100 regulates IGF1-receptor expression in metastatic pancreatic cancer cells by Huang, J S, Egger, M E, Grizzle, W E, McNally, L R

“…Patients with pancreatic adenocarcinoma have the lowest 5 year survival rate and yearly rates of incidence are nearly equal to the mortality rates. Long term…”
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Post-transcriptional processing of genetic information and its relation to cancer by McNally, Lr, Manne, U, Grizzle, W E

“…During the development, progression and dissemination of neoplastic lesions, cancer cells hijack normal pathways and mechanisms, especially those involved in…”
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The effects of frozen tissue storage conditions on the integrity of RNA and protein by Auer, H, Mobley, J A, Ayers, L W, Bowen, J, Chuaqui, R F, Johnson, L A, Livolsi, V A, Lubensky, I A, McGarvey, D, Monovich, L C, Moskaluk, C A, Rumpel, C A, Sexton, K C, Washington, M K, Wiles, K R, Grizzle, W E, Ramirez, N C

“…Unfixed tissue specimens most frequently are stored for long term research uses at either -80° C or in vapor phase liquid nitrogen (VPLN). There is little…”
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Chemoresistance in ovarian cancer linked to expression of microRNAs by Frederick, P J, Green, H N, Huang, J S, Egger, M E, Frieboes, H B, Grizzle, W E, McNally, L R

“…We evaluated the differential expression of several microRNAs (miRNAs) among malignant cells in ascites and matched omental metastasis in patients with…”
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Aging Alters Zonation in the Adrenal Cortex of Men by Parker, C. R, Mixon, R. L, Brissie, R. M, Grizzle, W. E

“…Whereas aging has been shown to be associated with striking reductions in circulating levels of adrenal androgens in humans, the alteration in adrenal function…”
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CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma by Kaliberova, L N, Krendelchtchikova, V, Harmon, D K, Stockard, C R, Petersen, A S, Markert, J M, Gillespie, G Y, Grizzle, W E, Buchsbaum, D J, Kaliberov, S A

“…Malignant forms of glioma, the most common primary brain tumors, remain poorly responsive to multimodality therapeutic interventions, including chemotherapy…”
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Selective COX-2 inhibitor (celecoxib) decreases cellular growth in prostate cancer cell lines independent of p53 by Katkoori, V R, Manne, K, Vital-Reyes, V S, Rodríguez-Burford, C, Shanmugam, C, Sthanam, M, Manne, U, Chatla, C, Abdulkadir, S A, Grizzle, W E

“…Celecoxib is a clinically available COX-2 inhibitor that has been reported to have antineoplastic activity. It has been proposed as a preventative agent for…”
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Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors by EVERTS, M, KIM-PARK, S.-A, PREUSS, M. A, PASSINEAU, M. J, GLASGOW, J. N, PEREBOEV, A. V, MAHASRESHTI, P. J, GRIZZLE, W. E, REYNOLDS, P. N, CURIEL, D. T

“…Targeted therapies directed to tumor-associated antigens are being investigated for the treatment of cancer. However, there are few suitable animal models for…”
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Promoter Deletion and Loss of Retinoblastoma Gene Expression in Human Prostate Carcinoma by Bookstein, Robert, Rio, Pascale, Madreperla, Steven A., Hong, Frank, Allred, Craig, Grizzle, William E., Lee, Wen-Hwa

“…Mutational inactivation of the retinoblastoma gene (RB) is found in all retinoblastomas and in a subset of other human neoplasms, including sarcomas of bone or…”
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Racial Differences in the Prognostic Usefulness of MUC1 and MUC2 in Colorectal Adenocarcinomas by MANNE, Upender, WEISS, Heidi L, GRIZZLE, William E

“…There is a need for new prognostic parameters that could add insights into the aggressiveness of tumors. Because the expression of two well-characterized mucin…”
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Exosomes and immune surveillance of neoplastic lesions: a review by Zhang, H-G, Zhuang, X, Sun, D, Liu, Y, Xiang, X, Grizzle, W E

“…The immune system has been reported to suppress the development and progression of neoplastic lesions; however, the exact mechanisms by which neoplastic…”
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Nuclear accumulation of p53 in colorectal adenocarcinoma : Prognostic importance differs with race and location of the tumor by MANNE, U, WEISS, H. L, MYERS, R. B, DANNER, O. K, MORON, C, SRIVASTAVA, S, GRIZZLE, W. E

“…Although several studies have been conducted to examine the role of p53 genetic abnormalities and their prognostic value in colorectal carcinoma, the incidence…”
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