Search Results - "GRISSOM, Charles B"

Synthesis and Characterization of a Cobalamin−Colchicine Conjugate as a Novel Tumor-Targeted Cytotoxin by Bagnato, Joshua D, Eilers, Alanna L, Horton, Robert A, Grissom, Charles B

“…Colchicine was derivatized at C7 with p-alkoxyacetophenone and conjugated to cobalamin (vitamin B12) through an acid-labile hydrazone linker. The cobalamin…”
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Magnetic Spin Effects in Enzymatic Reactions:  Radical Oxidation of NADH by Horseradish Peroxidase by Afanasyeva, Maria S, Taraban, Marc B, Purtov, Peter A, Leshina, Tatyana V, Grissom, Charles B

“…A description of the elementary steps of the horseradish peroxidase (HRP)-catalyzed oxidation of NADH is presented, along with a quantitative analysis of the…”
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Design, Synthesis, and Characterization of Fluorescent Cobalamin Analogues with High Quantum Efficiencies by Lee, Manfai, Grissom, Charles B

“…Cobalamin tethered to fluorescein or Rhodamine 6G has been synthesized and characterized. The fluorophore is conjugated to the ribose-5′-OH of cobalamin…”
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Synthesis and Characterization of Fluorescent Cobalamin (CobalaFluor) Derivatives for Imaging by Smeltzer, Claudia C, Cannon, Michelle J, Pinson, Patrick R, Munger, John D, West, Frederick G, Grissom, Charles B

“…Fluorescent derivatives of cobalamin have been prepared by linking fluorophores to cobalamin through a propylamide spacer. Fluorescein, naphthofluorescein, and…”
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Magnetic Field Dependence of Electron Transfer and the Role of Electron Spin in Heme Enzymes:  Horseradish Peroxidase by Taraban, Marc B, Leshina, Tatyana V, Anderson, Mark A, Grissom, Charles B

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Magnetic Field Effects in Biology: A Survey of Possible Mechanisms with Emphasis on Radical-Pair Recombination by Grissom, Charles B

“…Biological magnetic field effects for which plausible chemical mechanisms have been put forth are examined. Phenomenological-based observations that cannot be…”
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Application of a fluorescent cobalamin analogue for analysis of the binding kinetics. A study employing recombinant human transcobalamin and intrinsic factor by Fedosov, Sergey N, Grissom, Charles B, Fedosova, Natalya U, Moestrup, Søren K, Nexø, Ebba, Petersen, Torben E

“…Fluorescent probe rhodamine was appended to 5' OH-ribose of cobalamin (Cbl). The prepared conjugate, CBC, bound to the transporting proteins, intrinsic factor…”
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Application of a fluorescent cobalamin analogue for analysis of the binding kinetics by Fedosov, Sergey N., Grissom, Charles B., Fedosova, Natalya U., Moestrup, Søren K., Nexø, Ebba, Petersen, Torben E.

“…Fluorescent probe rhodamine was appended to 5′ OH‐ribose of cobalamin (Cbl). The prepared conjugate, CBC, bound to the transporting proteins, intrinsic factor…”
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Increasing the Heavy Atom Effect of Xenon by Adsorption to Zeolites:  Photolysis of 2,3-Diazabicyclo[2.2.2]oct-2-ene by Anderson, Mark A, Grissom, Charles B

“…The distribution of products in the photolysis of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) is determined by the electronic spin state of the cyclohexane-1,4-diyl…”
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Ultra-Performance Liquid Chromatographic Separation and Mass Spectrometric Quantitation of Physiologic Cobalamins by Owen, Shawn C., Lee, Manfai, Grissom, Charles B.

“…The current analytical high-performance liquid chromatography (HPLC) methods by which the various forms of cobalamin can be separated and quantified are…”
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Elementary Steps of Enzymatic Oxidation of Nifedipine Catalyzed by Horseradish Peroxidase by Afanasyeva, Maria S, Taraban, Marc B, Polyakov, Nikolay E, Purtov, Peter A, Leshina, Tatyana V, Grissom, Charles B

“…The elementary steps of the enzymatic oxidation of nifedipine (NF) catalyzed by horseradish peroxidase (HRP) have been described based on analysis of kinetic…”
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Magnetic field effects on B12 ethanolamine ammonia lyase : evidence for a radical mechanism by HARKINS, T. T, GRISSOM, C. B

“…A change in radical pair recombination rates is one of the few mechanisms by which a magnetic field can interact with a biological system. The kinetic…”
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Isotope effect studies of chicken liver NADP malic enzyme: role of the metal ion and viscosity dependence by Grissom, Charles B, Cleland, W. W

“…The role of the metal ion in the oxidative decarboxylation of malate by chicken liver NADP malic enzyme and details of the reaction mechanism have been…”
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Structural Determination of 5‘-OH α-Ribofuranoside Modified Cobalamins via 13C and DEPT NMR by Horton, Robert A, Bagnato, Joshua D, Grissom, Charles B

“…A protocol for the rapid NMR characterization of cobalamin (vitamin B12) analogues with 5‘-hydroxy-α-ribofuranoside modification is reported. The structure of…”
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Magnetic field effects in adenosylcob(III)alamin photolysis: relevance to B12 enzymes by Chagovetz, Alexander M, Grissom, Charles B

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Electron Spin Catalysis by Xenon in an Enzyme by Anderson, Mark A, Xu, Yaping, Grissom, Charles B

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Alkyl Radical Geometry Controls Geminate Cage Recombination in Alkylcobalamins by Lott, William B, Chagovetz, Alexander M, Grissom, Charles B

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The Magnetic Field Dependent Step in B12 Ethanolamine Ammonia Lyase Is Radical-Pair Recombination by Harkins, Timothy T, Grissom, Charles B

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Mechanistic probes of monoamine oxidase B catalysis: Rapid-scan stopped flow and magnetic field independence of the reductive half-reaction by Miller, J. Richard, Edmondson, Dale E, Grissom, Charles B

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CIDNP in the Photolysis of Coenzyme B12 Model Compounds Suggesting That C−Co Bond Homolysis Occurs from the Singlet State by Kruppa, Alexander I, Taraban, Marc B, Leshina, Tatyana V, Natarajan, Ettaya, Grissom, Charles B

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