Search Results - "GRISHAM, M. B"

Emerging roles of lymphatics in inflammatory bowel disease by Alexander, J. Steven, Chaitanya, Ganta Vijay, Grisham, M.B., Boktor, Moheb

“…The mobilization and recruitment of blood and lymphatic vasculatures are widely described in inflammatory bowel diseases (IBDs). Although angiogenesis…”
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Evaluation of the immunoregulatory activity of intraepithelial lymphocytes in a mouse model of chronic intestinal inflammation by Ostanin, D. V., Brown, C. M., Gray, L., Bharwani, S., Grisham, M. B.

“…Intraepithelial lymphocytes (IELs) represent the first line of lymphocyte defense against the intestinal bacteria. Although previous studies have demonstrated…”
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Modulation of Ischemia/Reperfusion-Induced Microvascular Dysfunction by Nitric Oxide by Kurose, Iwao, Wolf, Robert, Grisham, Matthew B, Granger, D Neil

“…Leukocyte-endothelial cell adhesion and an altered metabolism of endothelial cell-derived nitric oxide (NO) have been implicated in the microvascular…”
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Review article: chronic inflammation and reactive oxygen and nitrogen metabolism – implications in DNA damage and mutagenesis by Grisham, M. B., Jourd'Heuil, D., Wink, D. A.

“…Summary It is well known that chronic inflammation of the digestive tract is associated with an increased risk of malignant transformation. Because phagocytic…”
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Oxidants and free radicals in inflammatory bowel disease by Grisham, M B

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Inflammation, free radicals, and antioxidants by Conner, Elaine M., Grisham, Matthew B.

“…It is becoming increasingly apparent that certain types of inflammatory tissue injury are mediated by reactive oxygen metabolites. The most likely sources of…”
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Role of nitric oxide in inflammation by Laroux, F. S., Pavlick, K. P., Hines, I. N., Kawachi, S., Harada, H., Bharwani, S., Hoffman, J. M., Grisham, M. B.

“…A number of laboratories have sought to elucidate the role of nitric oxide (NO) in both acute and chronic inflammatory diseases. It is now well appreciated…”
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Combination of Donor-Specific Blood Transfusion With Anti-CD28 Antibody Synergizes to Prolong Graft Survival in Rat Liver Transplantation by Urakami, H., Ostanin, D.V., Hünig, T., Grisham, M.B.

“…Donor-specific blood transfusion (DST) has been shown to effectively induce tolerance to certain allografts. In addition, it is well known that blockade of…”
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Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis by Grisham, M B, Specian, R D, Zimmerman, T E

“…The objective of this study was to assess the role that nitric oxide (NO) may play in mediating the colonic inflammation observed in a model of chronic…”
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Increased disease activity in eNOS-deficient mice in experimental colitis by Sasaki, M, Bharwani, S, Jordan, P, Elrod, J.W, Grisham, M.B, Jackson, T.H, Lefer, D.J, Alexander, J.Steven

“…Oral dextran sodium sulfate (DSS, 3%) produces experimental colitis with many features of human inflammatory bowel disease (IBD), (leukocyte extravasation,…”
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Role of neutrophils in ischemia-reperfusion-induced microvascular injury by Hernandez, L A, Grisham, M B, Twohig, B, Arfors, K E, Harlan, J M, Granger, D N

“…Recent studies indicate that polymorphonuclear neutrophils (PMNs) infiltrate the intestinal mucosa during ischemia and after reperfusion. To determine whether…”
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Expression of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in acute and chronic inflammation by Connor, Elaine M., Eppihimer, Michael J., Morise, Zenichi, Granger, D. Neil, Grisham, Matthew B.

“…The objective of this study was to quantify, in vivo, constitutive and tumor necrosis factor α (TNF‐α)‐enhanced expression of mucosal addressin cell adhesion…”
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Effects of an endogenous inhibitor of nitric oxide synthesis on postcapillary venules by Kurose, I, Wolf, R, Grisham, M B, Granger, D N

“…The objective of this study was to determine whether an inhibitor of nitric oxide (NO) synthase (NG,NG'-dimethyl-L-arginine; L-DMA) that is produced by…”
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Leukocyte adherence to venular endothelium during ischemia-reperfusion by Granger, D N, Benoit, J N, Suzuki, M, Grisham, M B

“…Xanthine oxidase-derived oxidants and leukocytes have been implicated in the microvascular injury associated with reperfusion of ischemic intestine. The…”
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Superoxide mediates reperfusion-induced leukocyte-endothelial cell interactions by Suzuki, M, Inauen, W, Kvietys, P R, Grisham, M B, Meininger, C, Schelling, M E, Granger, H J, Granger, D N

“…The objective of this study was to determine whether superoxide mediates the leukocyte-endothelial cell interactions elicited by reperfusion (reoxygenation) of…”
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Xanthine oxidase and neutrophil infiltration in intestinal ischemia by Grisham, M B, Hernandez, L A, Granger, D N

“…A growing body of experimental data indicates that reactive oxygen metabolites such as superoxide, hydrogen peroxide, and hydroxyl radical may mediate the…”
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Leukocyte depletion attenuates vascular injury in postischemic skeletal muscle by Korthuis, R J, Grisham, M B, Granger, D N

“…To determine whether leukocytes play an important role in the pathogenesis of the vascular injury (increased vascular permeability and resistance) associated…”
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Indomethacin induced gastropathy in CD18, intercellular adhesion molecule 1, or P-selectin deficient mice by Morise, Z, Granger, D N, Fuseler, J W, Anderson, D C, Grisham, M B

“…BACKGROUND Neutrophil-endothelial cell interactions are thought to play a critical role in the pathophysiology of non-steroidal anti-inflammatory drug (NSAID)…”
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Effects of reactive metabolites of oxygen and nitrogen on gelatinase A activity by Owens, M W, Milligan, S A, Jourd'heuil, D, Grisham, M B

“…The regulation of matrix metalloproteinase activity is crucial for maintaining the proper balance of tissue remodeling vs. injury. Metalloproteinase proenzymes…”
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Role of oxidants in ischemia/reperfusion-induced granulocyte infiltration by Zimmerman, B J, Grisham, M B, Granger, D N

“…The objective of this study was to determine whether hydrogen peroxide, iron, and/or hydroxyl radicals play a role in ischemia/reperfusion (I/R)-induced…”
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