Search Results - "GRINBERG, L. T"

Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease by Ehrenberg, A. J., Nguy, A. K., Theofilas, P., Dunlop, S., Suemoto, C. K., Di Lorenzo Alho, A. T., Leite, R. P., Diehl Rodriguez, R., Mejia, M. B., Rüb, U., Farfel, J. M., Lucena Ferretti‐Rebustini, R. E., Nascimento, C. F., Nitrini, R., Pasquallucci, C. A., Jacob‐Filho, W., Miller, B., Seeley, W. W., Heinsen, H., Grinberg, L. T.

“…AimsHyperphosphorylated tau neuronal cytoplasmic inclusions (ht‐NCI) are the best protein correlate of clinical decline in Alzheimer's disease (AD)…”
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The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset? by Grinberg, L. T., Rüb, U., Ferretti, R. E. L., Nitrini, R., Farfel, J. M., Polichiso, L., Gierga, K., Jacob-Filho, W., Heinsen, H.

“…Aims: Alzheimer's disease (AD) is a progressive and irreversible disease. There is strong evidence that the progression of the phospho‐tau neurofibrillary…”
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Neuropathologic features associated with Alzheimer disease diagnosis: Age matters by MIDDLETON, L. E, GRINBERG, L. T, MILLER, B, KAWAS, C, YAFFE, K

“…To examine whether the association between clinical Alzheimer disease (AD) diagnosis and neuropathology and the precision by which neuropathology…”
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Prevalence of transactive response DNA‐binding protein 43 (TDP‐43) proteinopathy in cognitively normal older adults: systematic review and meta‐analysis by Nascimento, C., Di Lorenzo Alho, A. T., Bazan Conceição Amaral, C., Leite, R. E. P., Nitrini, R., Jacob‐Filho, W., Pasqualucci, C. A., Hokkanen, S. R. K., Hunter, S., Keage, H., Kovacs, G. G., Grinberg, L. T., Suemoto, C. K.

“…Objective To perform a systematic review and meta‐analysis on the prevalence of transactive response DNA‐binding protein 43 (TDP‐43) proteinopathy in…”
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The behavioral variant of Alzheimer's disease does not show a selective loss of Von Economo and phylogenetically related neurons in the anterior cingulate cortex by Singleton, E H, Pijnenburg, Y A L, Gami-Patel, P, Boon, B D C, Bouwman, F, Papma, J M, Seelaar, H, Scheltens, P, Grinberg, L T, Spina, S, Nana, A L, Rabinovici, G D, Seeley, W W, Ossenkoppele, R, Dijkstra, A A

“…The neurobiological origins of the early and predominant behavioral changes seen in the behavioral variant of Alzheimer's disease (bvAD) remain unclear. A…”
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Pathoarchitectonics of the cerebral cortex in chorea‐acanthocytosis and Huntington's disease by Liu, J., Heinsen, H., Grinberg, L. T., Alho, E., Amaro, E., Pasqualucci, C. A., Rüb, U., Seidel, K., den Dunnen, W., Arzberger, T., Schmitz, C., Kiessling, M. C., Bader, B., Danek, A.

“…Aims Quantitative estimation of cortical neurone loss in cases with chorea‐acanthocytosis (ChAc) and its impact on laminar composition. Methods We used…”
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ALS and FTLD: two faces of TDP-43 proteinopathy by Liscic, R. M., Grinberg, L. T., Zidar, J., Gitcho, M. A., Cairns, N. J.

“…Major discoveries have been made in the recent past in the genetics, biochemistry and neuropathology of frontotemporal lobar degeneration (FTLD). TAR…”
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African ancestry protects against Alzheimer's disease-related neuropathology by Schlesinger, D, Grinberg, L T, Alba, J G, Naslavsky, M S, Licinio, L, Farfel, J M, Suemoto, C K, de Lucena Ferretti, R E, Leite, R E P, de Andrade, M P, dos Santos, A C F, Brentani, H, Pasqualucci, C A, Nitrini, R, Jacob-Filho, W, Zatz, M

“…Previous studies in dementia epidemiology have reported higher Alzheimer's disease rates in African-Americans when compared with White Americans. To determine…”
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d-serine levels in Alzheimer’s disease: implications for novel biomarker development by Madeira, C, Lourenco, M V, Vargas-Lopes, C, Suemoto, C K, Brandão, C O, Reis, T, Leite, R E P, Laks, J, Jacob-Filho, W, Pasqualucci, C A, Grinberg, L T, Ferreira, S T, Panizzutti, R

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d-serine levels in Alzheimer’s disease: implications for novel biomarker development by Madeira, C, Lourenco, M V, Vargas-Lopes, C, Suemoto, C K, Brandão, C O, Reis, T, Leite, R E P, Laks, J, Jacob-Filho, W, Pasqualucci, C A, Grinberg, L T, Ferreira, S T, Panizzutti, R

“…Alzheimer’s disease (AD) is a severe neurodegenerative disorder still in search of effective methods of diagnosis. Altered levels of the NMDA receptor…”
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Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD by RABINOVICI, G. D, ROSEN, H. J, GROWDON, M. E, JANG, J. Y, HUANG, E. J, DEARMOND, S. J, TROJANOWSKI, J. Q, GRINBERG, L. T, GORNO-TEMPINI, M. L, SEELEY, W. W, MILLER, B. L, JAGUST, W. J, ALKALAY, A, KORNAK, J, FURST, A. J, AGARWAL, N, MORMINO, E. C, O'NEIL, J. P, JANABI, M, KARYDAS, A

“…To compare the diagnostic performance of PET with the amyloid ligand Pittsburgh compound B (PiB-PET) to fluorodeoxyglucose (FDG-PET) in discriminating between…”
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TDP-43 frontotemporal lobar degeneration and autoimmune disease by Miller, Zachary A, Rankin, Katherine P, Graff-Radford, Neill R, Takada, Leonel T, Sturm, Virginia E, Cleveland, Clare M, Criswell, Lindsey A, Jaeger, Philipp A, Stan, Trisha, Heggeli, Kristin A, Hsu, Sandy Chan, Karydas, Anna, Khan, Baber K, Grinberg, Lea T, Gorno-Tempini, Maria Luisa, Boxer, Adam L, Rosen, Howard J, Kramer, Joel H, Coppola, Giovanni, Geschwind, Daniel H, Rademakers, Rosa, Seeley, William W, Wyss-Coray, Tony, Miller, Bruce L

“…Background The aetiology and pathogenesis of non-genetic forms of frontotemporal dementia (FTD) is unknown and even with the genetic forms of FTD, pathogenesis…”
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A 44-year-old man with profound behavioural changes by Laforce, Jr, R, Kerchner, G A, Rabinovici, G D, Fong, J C, Miller, B L, Seeley, W W, Grinberg, L T

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Brazilian psychiatric brain bank: a new contribution tool to network studies by de Oliveira, K. C., Nery, F. G., Ferreti, R. E. L., Lima, M. C., Cappi, C., Machado-Lima, A., Polichiso, L., Carreira, L. L., Ávila, C., Alho, A. T. D. L., Brentani, H. P., Miguel, E. C., Heinsen, H., Jacob-Filho, W., Pasqualucci, C. A., Lafer, B., Grinberg, L. T.

“…There is an urgent need for expanding the number of brain banks serving psychiatric research. We describe here the Psychiatric Disorders arm of the Brain Bank…”
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Regional and hemispheric susceptibility of the temporal lobe to FTLD-TDP type C pathology by Borghesani, V., Battistella, G., Mandelli, M.L., Welch, A., Weis, E., Younes, K., Neuhaus, J., Grinberg, L.T., Seeley, W.M., Spina, S., Miller, B., Miller, Z., Gorno-Tempini, M.L.

“…•Anterior temporal lobe (ATL) degeneration is most often caused by FTLD-TDP type C pathology.•Cases can present with predominantly left (60%) or right (40%)…”
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Magnetic resonance diffusion tensor imaging for the pedunculopontine nucleus: proof of concept and histological correlation by Alho, A. T. D. L., Hamani, C., Alho, E. J. L., da Silva, R. E., Santos, G. A. B., Neves, R. C., Carreira, L. L., Araújo, C. M. M., Magalhães, G., Coelho, D. B., Alegro, M. C., Martin, M. G. M., Grinberg, L. T., Pasqualucci, C. A., Heinsen, H., Fonoff, E. T., Amaro, E.

“…The pedunculopontine nucleus (PPN) has been proposed as target for deep brain stimulation (DBS) in patients with postural instability and gait disorders due to…”
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Combined enrichment of neuromelanin granules and synaptosomes from human substantia nigra pars compacta tissue for proteomic analysis by Plum, S., Helling, S., Theiss, C., Leite, R.E.P., May, C., Jacob-Filho, W., Eisenacher, M., Kuhlmann, K., Meyer, H.E., Riederer, P., Grinberg, L.T., Gerlach, M., Marcus, K.

“…This article gives a detailed description of a protocol using density gradient centrifugation for the enrichment of neuromelanin granules and synaptosomes from…”
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Trace element concentration differences in regions of human brain by INAA by Saiki, M., Leite, R. E. P., Genezini, F. A., Grinberg, L. T., Ferretti, R. E. L., Farfel, J. M., Suemoto, C., Pasqualucci, C. A., Jacob-Filho, W.

“…Studies have shown that there is a potential relationship between the levels of trace elements in cerebral tissues and neurological disorders. However, there…”
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Determination of trace elements in human brain tissues using neutron activation analysis by Leite, R. E. P., Jacob-Filho, W., Saiki, M., Grinberg, L. T., Ferretti, R. E. L.

“…Neutron activation analysis was applied to assess trace element concentrations in brain tissues from normal ( n = 21) and demented individuals ( n = 21) of…”
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Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration by Thijssen, Elisabeth H., La Joie, Renaud, Wolf, Amy, Strom, Amelia, Wang, Ping, Iaccarino, Leonardo, Bourakova, Viktoriya, Cobigo, Yann, Heuer, Hilary, Spina, Salvatore, VandeVrede, Lawren, Chai, Xiyun, Proctor, Nicholas K., Airey, David C., Shcherbinin, Sergey, Duggan Evans, Cynthia, Sims, John R., Zetterberg, Henrik, Blennow, Kaj, Karydas, Anna M., Teunissen, Charlotte E., Kramer, Joel H., Grinberg, Lea T., Seeley, William W., Rosen, Howie, Boeve, Bradley F., Miller, Bruce L., Rabinovici, Gil D., Dage, Jeffrey L., Rojas, Julio C., Boxer, Adam L.

“…With the potential development of new disease-modifying Alzheimer’s disease (AD) therapies, simple, widely available screening tests are needed to identify…”
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