Search Results - "GRIGORESCU, FLORIN"

Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation by Haydar, Sara, Grigorescu, Florin, Vintilă, Mădălina, Cogne, Yannick, Lautier, Corinne, Tutuncu, Yildiz, Brun, Jean Frederic, Robine, Jean Marie, Pugeat, Michel, Normand, Christophe, Poucheret, Patrick, Gheorghiu, Monica Livia, Georgescu, Carmen, Badiu, Corin, Băculescu, Nicoleta, Renard, Eric, Ylli, Dorina, Badiou, Stephanie, Sutra, Thibault, Cristol, Jean Paul, Mercier, Jacques, Gomis, Ramon, Macias, Josep Maria, Litvinov, Serghey, Khusnutdinova, Elza, Poiana, Catalina, Pasquali, Renato, Lauro, Davide, Sesti, Giorgio, Prudente, Sabrina, Trischitta, Vincenzo, Tsatsoulis, Agathocles, Abdelhak, Sonia, Barakat, Abdelhamid, Zenati, Akila, Ylli, Agron, Satman, Ilhan, Kanninen, Timo, Rinato, Yves, Missoni, Sasa

“…Branched chain amino acids (BCAA) are essential elements of the human diet, which display increased plasma levels in obesity and regained particular interest…”
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IGF-I Receptor Mutations Resulting in Intrauterine and Postnatal Growth Retardation by Abuzzahab, M. Jennifer, Schneider, Anke, Goddard, Audrey, Grigorescu, Florin, Lautier, Corinne, Keller, Eberhard, Kiess, Wieland, Klammt, Jürgen, Kratzsch, Jürgen, Osgood, Doreen, Pfäffle, Roland, Raile, Klemens, Seidel, Berthold, Smith, Robert J, Chernausek, Steven D

“…Two children with intrauterine growth retardation and short stature who had mutations in the gene for the insulin-like growth factor I receptor ( IGF-IR ) were…”
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Branched-Chain Amino Acid Database Integrated in MEDIPAD Software as a Tool for Nutritional Investigation of Mediterranean Populations by Haydar, Sara, Paillot, Thomas, Fagot, Christophe, Cogne, Yannick, Fountas, Athanasios, Tutuncu, Yildiz, Vintila, Madalina, Tsatsoulis, Agathocles, Thanh Chi, Pham, Garandeau, Patrick, Chetea, Dan, Badiu, Corin, Gheorghiu, Monica, Ylli, Dorina, Lautier, Corinne, Jarec, Morana, Monnier, Louis, Normand, Christophe, Šarac, Jelena, Barakat, Abdelhamid, Missoni, Sasa, Pugeat, Michel, Poucheret, Patrick, Hanzu, Felicia, Gomis, Ramon, Macias, Josep Maria, Litvinov, Serghey, Khusnutdinova, Elza, Poiana, Catalina, Pasquali, Renato, Lauro, Davide, Sesti, Giorgio, Trischitta, Vincenzo, Abdelhak, Sonia, Zenati, Akila, Ylli, Agron, Satman, Ilhan, Kanninen, Timo, Rinato, Yves, Grigorescu, Florin

“…Branched-chained amino acids (BCAA) are essential dietary components for humans and can act as potential biomarkers for diabetes development. To efficiently…”
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Association of insulin receptor genetic variants with polycystic ovary syndrome in a population of women from Central Europe by Hanzu, Felicia A., M.D, Radian, Serban, M.D., Ph.D, Attaoua, Redha, Ph.D, Ait-El-Mkadem, Samira, Ph.D, Fica, Simona, M.D, Gheorghiu, Monica, M.D, Coculescu, Mihai, M.D., Ph.D, Grigorescu, Florin, M.D., Ph.D

“…To assess the role of the insulin receptor gene in polycystic ovary syndrome (PCOS) we performed a case-control study in a female population (n = 226) from…”
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Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in Moderate-to-Severe Insulin Resistance of Women With Polycystic Ovary Syndrome by SAMIRA AIT EL MKADEM, LAUTIER, Corinne, WHITE, Morris F, GRIGORESCU, Florin, MACARI, Francoise, MOLINARI, Nicolas, LEFEBVRE, Patrick, RENARD, Eric, GRIS, Jean Christophe, CROS, Gérard, DAURES, Jean Pierre, BRINGER, Jacques

“…Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in Moderate-to-Severe Insulin Resistance of Women With Polycystic Ovary Syndrome Samira Ait…”
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1702-P: Fine-Scale Haplotype Mapping of PPM1K Gene Reveals New Genetic Markers for the Study of Insulin Resistance at Clinical Scale by HAYDAR, SARA, LAUTIER, CORINNE, GRIGORESCU, FLORIN

“…Branched chain amino acids (BCAA) plasma levels represent potential biomarkers for development of type 2 diabetes (T2D). Mendelian randomization and…”
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Fine-Scale Haplotype Mapping Reveals an Association of the FTO Gene with Osteoporosis and Fracture Risk in Postmenopausal Women by Greere, Daniela, Haydar, Sara, Grigorescu, Florin, Manda, Dana, Voicu, Gabriela, Lautier, Corinne, Poiana, Catalina

“…The Fat Mass and Obesity-Associated ( ) gene encodes a demethylase, which modulates RNA N6-methyladenosine (m6A) and plays a regulatory role in adipocyte…”
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Sequential first-line treatment with gemcitabine plus nab-paclitaxel (GA) followed by FOLFIRINOX (FFX) versus FFX alone in patients with metastatic pancreatic cancer (PC): GABRINOX-2 randomized phase 2 trial by Portales, Fabienne, Assenat, Eric, Samalin, Emmanuelle, Mazard, Thibault, Adenis, Antoine, Suchet Gallet, Blandine, Fiess, Catherine, Moussion, Aurore, Delaine, Stephanie, Grigorescu, Florin, Gourgou, Sophie, Ychou, Marc

“…TPS4190 Background: PC is a major health concern worldwide and a deadly disease due to its high metastatic behavior. In recent years, incremental progresses…”
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Relative Contribution of Metabolic Syndrome Components in Relation to Obesity and Insulin Resistance in Postmenopausal Osteoporosis by Greere, Daniela, Grigorescu, Florin, Manda, Dana, Voicu, Gabriela, Lautier, Corinne, Nitu, Ileana, Poiana, Catalina

“… Osteoporosis (OP) affects 30% of postmenopausal women, often complicated by metabolic syndrome (MetS) with a still controversial role. We aimed to…”
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Sequential treatment with gemcitabine/nab-paclitaxel (GA) and FOLFIRINOX (FFX) followed by stereotactic MRI-guided adaptive radiation therapy (SMART) in patients with locally advanced pancreatic cancer (LAPC): GABRINOX-ART phase 2, multicenter trial by Portales, Fabienne, Ychou, Marc, Samalin, Emmanuelle, Assenat, Eric, Obled, Stephane, Tyran, Marguerite, Mitry, Emmanuel, Rouffiac, Magali, Ghiringhelli, François, Bachet, Jean-Baptiste, Simon, Jean-Marc, De Ridder, Mark, Fiess, Catherine, Moussion, Aurore, Delaine, Stephanie, Grigorescu, Florin, Gourgou, Sophie, Riou, Olivier

“…TPS4191 Background: LAPC represents a major challenge with no standardized chemotherapy (CT) and radiotherapy (RT) treatment. Phase 2 studies (LAPACT/NEOLAP)…”
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Association of estrogen receptor gene variants (ESR1 and ESR2) with polycystic ovary syndrome in Tunisia by Douma, Zeineb, Dallel, Meriem, Bahia, Weal, Ben Salem, Assila, Hachani Ben Ali, Faten, Almawi, Wassim Y., Lautier, Corinne, Haydar, Sara, Grigorescu, Florin, Mahjoub, Touhemi

“…•SNVs in estrogen receptor genes are markers for cancer but poorly studied in PCOS.•Several SNVs in ESR1/2 genes were found associated with PCOS in Tunisian…”
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HOW GENETICISTS CONTRIBUTE TO UNDERSTANDING OF COVID-19 DISEASE PATHOGENICITY by Grigorescu, F, Lautier, C

“…Human populations are faced to the COVID-19 pandemic due to the emerging SARS-CoV-2 coronavirus originating from Wuhan (China) and with dramatic Public Health…”
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MEDIGENE PROGRAM REWARDED WITH THE EUROPEAN STARS AWARD 2017 by Grigorescu, F

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Association of ATF5 Gene with Metabolic Syndrome and Insulin Resistance in Mediterranean Populations by HAYDAR, SARA, GRIGORESCU, FLORIN, LAUTIER, CORINNE, NORMAND, CHRISTOPHE, HADI, JEAN CHRISTOPHE, VINTILA, MADALINA, GHEORGHIU, MONICA, FOUNTAS, ATHANASIOS, TSATSOULIS, AGATHOCLES, COPOLA, ANDREA, LAURO, DAVIDE, YLLI, DORINA, YLLI, AGRON, BRUGNARA, LAURA, HANZU, FELICIA, GOMIS, RAMON

“…Insulin resistance (InsR) characterizes the metabolic syndrome (MetS) for which many genes were involved by GWAS. To further explore genetic susceptibility…”
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Characterization of vanadyl sulfate effect on vascular contraction: roles of calcium and tyrosine phosphorylation by Cadène, A, Grigorescu, F, Serrano, J J, Cros, G

“…In order to explore the mechanism of action of vanadyl sulfate (VOSO4), previously described as an antidiabetic and antihypertensive agent, we have…”
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Haplotyping strategy highlights the specificity of FTO gene association with polycystic ovary syndrome in Tunisian women population by Ben Salem, Assila, Attaoua, Redha, Mtiraoui, Nabil, Meddeb, Sawssen, Kacem, Olfa, Ajina, Mounir, Souissi, Moncef, Poucheret, Patrick, Normand, Christophe, Mahjoub, Touhami, Grigorescu, Florin

“…The FTO (fat mass and obesity associated) gene was associated with different metabolic disorders in populations from different origins but with great…”
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PP-013 - Common polymorphisms of calpin-10 and the risk of polycystic ovary syndrome in a Tunisian population by Ajina, Mounir, Kacem, Olfa, Salem, Assila Ben, Sallem, Amira, Poucheret, Patrick, Vintila, Madalina, Grigorescu, Florin, Mahjoub, Touhami, Saad, Ali

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BRANCHED CHAIN AMINO ACIDS AT THE EDGE BETWEEN MENDELIAN AND COMPLEX DISORDERS by Haydar, S, Lautier, C, Grigorescu, F

“…Branched chained amino acids (BCAA) are essential components of the human diet and important nutrient signals, which regain particular interest in recent years…”
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Association of genetic variants in the FTO gene with metabolic syndrome: A case-control study in the Tunisian population by Elouej, Sahar, Nagara, Majdi, Attaoua, Redha, Sallem, Om Kalthoum, Rejeb, Insaf, Hsouna, Sana, Lasram, Khaled, Halim, Nizar Ben, Chargui, Mariem, Jamoussi, Henda, Turki, Zinet, Kamoun, Ines, Belfki-Benali, Hanen, Abid, Abdelmajid, Slama, Claude Ben, Bahri, Sonia, Triki, Dalenda, Romdhane, Habiba Ben, Abdelhak, Sonia, Kefi, Rym, Grigorescu, Florin

“…Abstract Aims Variants in the fat mass and obesity-associated gene ( FTO ) are associated with obesity and type 2 diabetes. However, the association of FTO…”
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Gender-specific associations of genetic variants with metabolic syndrome components in the Tunisian population by Elouej, Sahar, Rejeb, Insaf, Attaoua, Redha, Nagara, Majdi, Sallem, Om Kalthoum, Kamoun, Ines, Chargui, Mariem, Jamoussi, Henda, Turki, Zinet, Abid, Abdelmajid, Ben Slama, Claude, Bahri, Sonia, Ben Romdhane, Habiba, Abdelhak, Sonia, Kefi, Rym, Grigorescu, Florin

“…Aim of the study: Recent genome-wide association studies (GWASs) have identified many genetic variants associated with metabolic syndrome (MetS). However,…”
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