Search Results - "GRIFFIOEN, Arjan W"

Galectin expression in cancer diagnosis and prognosis: A systematic review by Thijssen, Victor L., Heusschen, Roy, Caers, Jo, Griffioen, Arjan W.

“…Galectins are a family of proteins that bind to specific glycans thereby deciphering the information captured within the glycome. In the last two decades,…”
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The great escape; the hallmarks of resistance to antiangiogenic therapy by van Beijnum, Judy R, Nowak-Sliwinska, Patrycja, Huijbers, Elisabeth J M, Thijssen, Victor L, Griffioen, Arjan W

“…The concept of antiangiogenic therapy in cancer treatment has led to the approval of different agents, most of them targeting the well known vascular…”
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Galectin-9 in tumor biology: A jack of multiple trades by Heusschen, Roy, Griffioen, Arjan W., Thijssen, Victor L.

“…Galectin family members have been shown to exert multiple roles in the context of tumor biology. Several recent findings support a similar multi-faceted role…”
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Role of angiogenesis in adenomyosis-associated abnormal uterine bleeding and subfertility: a systematic review by Harmsen, Marissa J, Wong, Caroline F C, Mijatovic, Velja, Griffioen, Arjan W, Groenman, Freek, Hehenkamp, Wouter J K, Huirne, Judith A F

“…Abstract Background Adenomyosis commonly occurs with abnormal uterine bleeding (AUB) and is associated with subfertility and a higher miscarriage rate. Recent…”
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Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion by Cioni, Bianca, Zaalberg, Anniek, van Beijnum, Judy R., Melis, Monique H. M., van Burgsteden, Johan, Muraro, Mauro J., Hooijberg, Erik, Peters, Dennis, Hofland, Ingrid, Lubeck, Yoni, de Jong, Jeroen, Sanders, Joyce, Vivié, Judith, van der Poel, Henk G., de Boer, Jan Paul, Griffioen, Arjan W., Zwart, Wilbert, Bergman, Andries M.

“…The androgen receptor (AR) is the master regulator of prostate cancer (PCa) development, and inhibition of AR signalling is the most effective PCa treatment…”
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Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy by van Beijnum, Judy R., Huijbers, Elisabeth J. M., van Loon, Karlijn, Blanas, Athanasios, Akbari, Parvin, Roos, Arno, Wong, Tse J., Denisov, Stepan S., Hackeng, Tilman M., Jimenez, Connie R., Nowak-Sliwinska, Patrycja, Griffioen, Arjan W.

“…Anti-angiogenic cancer therapies possess immune-stimulatory properties by counteracting pro-angiogenic molecular mechanisms. We report that tumor endothelial…”
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Platelets as messengers of early-stage cancer by Sabrkhany, Siamack, Kuijpers, Marijke J. E., oude Egbrink, Mirjam G. A., Griffioen, Arjan W.

“…Platelets have an important role in tumor angiogenesis, growth, and metastasis. The reciprocal interaction between cancer and platelets results in changes of…”
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Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1) by van Beijnum, Judy R., Buurman, Wim A., Griffioen, Arjan W.

“…Sustained proinflammatory responses in rheumatoid arthritis, atherosclerosis, and diabetic retinopathy, as well as in cancer, are often associated with…”
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The role of blood platelets in tumor angiogenesis by Sabrkhany, Siamack, Griffioen, Arjan W., oude Egbrink, Mirjam G.A.

“…Coagulation abnormalities occur frequently in cancer patients. It is becoming evident that blood platelets have an important function in this process. However,…”
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Different angioregulatory activity of monovalent galectin-9 isoforms by Aanhane, Ed, Schulkens, Iris A., Heusschen, Roy, Castricum, Kitty, Leffler, Hakon, Griffioen, Arjan W., Thijssen, Victor L.

“…Galectin-9 consists of two peptide-linked carbohydrate recognition domains (CRDs), but alternative splicing and proteolytic processing can give rise to…”
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Role of the tumor stroma in resistance to anti-angiogenic therapy by Huijbers, Elisabeth J.M, van Beijnum, Judy R, Thijssen, Victor L, Sabrkhany, Siamack, Nowak-Sliwinska, Patrycja, Griffioen, Arjan W

“…Abstract Several angiogenesis inhibitors are currently used in the clinic for treatment of cancer. While anti-angiogenesis treatment can improve treatment…”
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Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance by GOTINK, Kristy J, BROXTERMAN, Henk J, GRIFFIOEN, Arjan W, ASSARAF, Yehuda G, PILI, Roberto, PETERS, Godefridus J, VERHEUL, Henk M. W, LABOTS, Mariette, DE HAAS, Richard R, DEKKER, Henk, HONEYWELL, Richard J, RUDEK, Michelle A, BEEREPOOT, Laurens V, MUSTERS, René J, JANSEN, Gerrit

“…Resistance to antiangiogenic tyrosine kinase inhibitors such as sunitinib is an important clinical problem, but its underlying mechanisms are largely unknown…”
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Targeting PDGF‐mediated recruitment of pericytes blocks vascular mimicry and tumor growth by Thijssen, Victor LJL, Paulis, Yvette WJ, Nowak‐Sliwinska, Patrycja, Deumelandt, Katrin L, Hosaka, Kayoko, Soetekouw, Patricia MMB, Cimpean, Anca M, Raica, Marius, Pauwels, Patrick, van den Oord, Joost J, Tjan‐Heijnen, Vivianne CG, Hendrix, Mary J, Heldin, Carl‐Henrik, Cao, Yihai, Griffioen, Arjan W

“…Aggressive tumor cells can adopt an endothelial cell‐like phenotype and contribute to the formation of a tumor vasculature, independent of tumor angiogenesis…”
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Age- and gender-matched controls needed for platelet-based biomarker studies by Sabrkhany, Siamack, Kuijpers, Marijke J E, Van Kuijk, Sander M J, Griffioen, Arjan W, Oude Egbrink, Mirjam G A

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Monocyte/macrophage infiltration in tumors: modulators of angiogenesis by Dirkx, Anita E. M., Egbrink, Mirjam G. A., Wagstaff, John, Griffioen, Arjan W.

“…The role of a tumor immune infiltrate in cancer progression and metastasis has been debated frequently. Although often considered to be associated with…”
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Tumor Cells Secrete Galectin-1 to Enhance Endothelial Cell Activity by THIJSSEN, Victor L, BARKAN, Batya, GRIFFIOEN, Arjan W, SHOJI, Hiroki, ARIES, Ingrid M, MATHIEU, Véronique, DELTOUR, Louise, HACKENG, Tilman M, KISS, Robert, KLOOG, Yoel, POIRIER, Françoise

“…Tumor angiogenesis is a key event in cancer progression. Here, we report that tumors can stimulate tumor angiogenesis by secretion of galectin-1. Tumor growth…”
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Multifunctional Nanoemulsion Platform for Imaging Guided Therapy Evaluated in Experimental Cancer by Gianella, Anita, Jarzyna, Peter A, Mani, Venkatesh, Ramachandran, Sarayu, Calcagno, Claudia, Tang, Jun, Kann, Benjamin, Dijk, Wouter J. R, Thijssen, Victor L, Griffioen, Arjan W, Storm, Gert, Fayad, Zahi A, Mulder, Willem J. M

“…Nanoparticle applications in medicine have seen a tremendous growth in the past decade. In addition to their drug targeting application and their ability to…”
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Endometrial Angiogenesis of Abnormal Uterine Bleeding and Infertility in Patients with Uterine Fibroids-A Systematic Review by Don, Emma E, Middelkoop, Mei-An, Hehenkamp, Wouter J K, Mijatovic, Velja, Griffioen, Arjan W, Huirne, Judith A F

“…Uterine fibroids are the most common benign tumors in women, with abnormal uterine bleeding (AUB) as the main reported symptom. Additionally, an association…”
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Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis by Derksen, Patrick W.B., Liu, Xiaoling, Saridin, Francis, van der Gulden, Hanneke, Zevenhoven, John, Evers, Bastiaan, van Beijnum, Judy R., Griffioen, Arjan W., Vink, Jacqueline, Krimpenfort, Paul, Peterse, Johannes L., Cardiff, Robert D., Berns, Anton, Jonkers, Jos

“…Metastatic disease is the primary cause of death in breast cancer, the most common malignancy in Western women. Loss of E-cadherin is associated with tumor…”
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Scheduling of Radiation with Angiogenesis Inhibitors Anginex and Avastin Improves Therapeutic Outcome via Vessel Normalization by DINGS, Ruud P. M, LOREN, Melissa, HEUN, Hanke, MCNIEL, Elizabeth, GRIFFIOEN, Arjan W, MAYO, Kevin H, GRIFFIN, Robert J

“…Purpose: To test whether a direct antiangiogenic peptide (anginex) and a vascular endothelial growth factor antibody (bevacizumab, Avastin) can transiently…”
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