Search Results - "GRIFFIN, John D"

Electoral Competition and Democratic Responsiveness: A Defense of the Marginality Hypothesis by Griffin, John D.

“…Does vigorous electoral competition help to convert citizens' preferences into government action? No, concludes a series of theoretical and empirical studies…”
Get full text

Intestinal Acyl-CoA synthetase 5 (ACSL5) deficiency potentiates postprandial GLP-1 & PYY secretion, reduces food intake, and protects against diet-induced obesity by Griffin, John D., Zhu, Ying, Reeves, Andrew, Buhman, Kimberly K., Greenberg, Andrew S.

“…In the small intestine, the products of digestion of dietary triacylglycerol (TAG), fatty acids (FA) and monoacylglycerol, are taken up by absorptive cells,…”
Get full text

A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction by Killion, Elizabeth A., Reeves, Andrew R., El Azzouny, Mahmoud A., Yan, Qing-Wu, Surujon, Defne, Griffin, John D., Bowman, Thomas A., Wang, Chunyan, Matthan, Nirupa R., Klett, Eric L., Kong, Dong, Newman, John W., Han, Xianlin, Lee, Mi-Jeong, Coleman, Rosalind A., Greenberg, Andrew S.

“…Regulation of fatty acid (FA) metabolism is central to adipocyte dysfunction during diet-induced obesity (DIO). Long-chain acyl-CoA synthetase-4 (ACSL4) has…”
Get full text

Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity by Flaherty, Stephen E., Bezy, Olivier, Zheng, Wei, Yan, Dong, Li, Xiangping, Jagarlapudi, Srinath, Albuquerque, Bina, Esquejo, Ryan M., Peloquin, Matthew, Semache, Meriem, Mancini, Arturo, Kang, Liya, Drujan, Doreen, Breitkopf, Susanne B., Griffin, John D., Jean Beltran, Pierre M., Xue, Liang, Stansfield, John, Pashos, Evanthia, Shakey, Quazi, Pehmøller, Christian, Monetti, Mara, Birnbaum, Morris J., Fortin, Jean-Philippe, Wu, Zhidan

“…Urocortin 2 (UCN2) acts as a ligand for the G protein-coupled receptor corticotropin-releasing hormone receptor 2 (CRHR2). UCN2 has been reported to improve or…”
Get full text

Integrated Action of Autophagy and Adipose Tissue Triglyceride Lipase Ameliorates Diet-Induced Hepatic Steatosis in Liver-Specific PLIN2 Knockout Mice by Griffin, John D, Bejarano, Eloy, Wang, Xiang-Dong, Greenberg, Andrew S

“…An imbalance in the storage and breakdown of hepatic lipid droplet (LD) triglyceride (TAG) leads to hepatic steatosis, a defining feature of non-alcoholic…”
Get full text

SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction by Flaherty, 3rd, Stephen E, Bezy, Olivier, Paulhus, Brianna LaCarubba, Song, LouJin, Piper, Mary, Pang, Jincheng, Park, Yoson, Asano, Shoh, Lien, Yu-Chin, Griffin, John D, Robertson, Andrew, Opsahl, Alan, Shanthappa, Dinesh Hirenallur, Ahn, Youngwook, Pashos, Evanthia, Simmons, Rebecca A, Birnbaum, Morris J, Wu, Zhidan

“…From a forward mutagenetic screen to discover mutations associated with obesity, we identified mutations in the gene linked to metabolic dysfunction in mice…”
Get full text

Voting Power, Policy Representation, and Disparities in Voting’s Rewards by Griffin, John D., Newman, Brian

“…Reelection-minded officials have motivations to represent some of their constituents more than others when casting roll-call votes. In particular, reelection…”
Get full text

Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption by Bowman, Thomas A, O'Keeffe, Kayleigh R, D'Aquila, Theresa, Yan, Qing Wu, Griffin, John D, Killion, Elizabeth A, Salter, Deanna M, Mashek, Douglas G, Buhman, Kimberly K, Greenberg, Andrew S

“…Abstract Objective The family of acyl-CoA synthetase enzymes (ACSL) activates fatty acids within cells to generate long chain fatty acyl CoA (FACoA). The…”
Get full text

Hepatic Activin E mediates liver-adipose inter-organ communication, suppressing adipose lipolysis in response to elevated serum fatty acids by Griffin, John D, Buxton, Joanne M, Culver, Jeffrey A, Barnes, Robert, Jordan, Emily A, White, Alexis R, Flaherty, Stephen E, Bernardo, Barbara, Ross, Trenton, Bence, Kendra K, Birnbaum, Morris J

“…The liver is a central regulator of energy metabolism exerting its influence both through intrinsic processing of substrates such as glucose and fatty acid as…”
Get full text

When and Why Minority Legislators Matter by Griffin, John D

“…This review examines how legislators' race and ethnicity affect the representation of racial and ethnic minorities' interests and priorities in the mass…”
Get full text

Class War in the Voting Booth: Bias Against High‐Income Congressional Candidates by Griffin, John D., Newman, Brian, Buhr, Patrick

“…Do Americans care how much money congressional candidates earn? We conducted three experiments to examine how candidates' incomes affect voters' perceptions of…”
Get full text

The effects of prostaglandin E2 on the firing rate activity of thermosensitive and temperature insensitive neurons in the ventromedial preoptic area of the rat hypothalamus by RANELS, Heather J, GRIFFIN, John D

“…In response to an immune system challenge with lipopolysaccharide (LPS), recent work has shown that Fos immunoreactivity is displayed by neurons in the…”
Get full text

Ventromedial Preoptic Prostaglandin E2 Activates Fever-Producing Autonomic Pathways by Scammell, Thomas E, Elmquist, Joel K, Griffin, John D, Saper, Clifford B

“…Fever is thought to be initiated by pyrogenic cytokines inducing the production of prostaglandin E2 (PGE2) in the preoptic area (POA); PGE2 may act as a…”
Get full text

Are Voters Better Represented? by Griffin, John D., Newman, Brian

“…Studies of political participation and representation often contend that elected officials respond more to the preferences of voters than those of nonvoters,…”
Get full text

The Unequal Representation of Latinos and Whites by Griffin, John D., Newman, Brian

“…We compare the ideological proximity of Latinos and whites to their Members of Congress (MCs), demonstrating the degree to which Latinos are underrepresented…”
Get full text

Electoral Competition and Democratic Responsiveness: A Defense of the Marginality Hypothesis by Griffin, John D.

“…Does vigorous electoral competition help to convert citizens' preferences into government action? No, concludes a series of theoretical and empirical studies…”
Get full text

Calcitonin gene-related peptide alters the firing rates of hypothalamic temperature sensitive and insensitive neurons by Braasch, Daniel C, Deegan, Erin M, Grimm, Eleanor R, Griffin, John D

“…Transient hyperthermic shifts in body temperature have been linked to the endogenous hormone calcitonin gene-related peptide (CGRP), which can increase…”
Get full text

Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution by Koprulu, Mine, Zhao, Yajie, Wheeler, Eleanor, Dong, Liang, Rocha, Nuno, Li, Chen, Griffin, John D, Patel, Satish, Van de Streek, Marcel, Glastonbury, Craig A, Stewart, Isobel D, Day, Felix R, Luan, Jian'an, Bowker, Nicholas, Wittemans, Laura B L, Kerrison, Nicola D, Cai, Lina, Lucarelli, Debora M E, Barroso, Inês, McCarthy, Mark I, Scott, Robert A, Saudek, Vladimir, Small, Kerrin S, Wareham, Nicholas J, Semple, Robert K, Perry, John R B, O'Rahilly, Stephen, Lotta, Luca A, Langenberg, Claudia, Savage, David B

“…Biological and translational insights from large-scale, array-based genetic studies of fat distribution, a key determinant of metabolic health, have been…”
Get full text

The effects of Cirazoline, an alpha-1 adrenoreceptor agonist, on the firing rates of thermally classified anterior hypothalamic neurons in rat brain slices by Imbery, Ted E, Irdmusa, Mitra S, Speidell, Andrew P, Streer, Mark S, Griffin, John D

“…Abstract Peripheral exposure to LPS induces a biphasic fever thought to be initiated via vagal afferents to the preoptic area of the anterior hypothalamus…”
Get full text

How Citizens and Their Legislators Prioritize Spheres of Representation by Griffin, John D., Flavin, Patrick

“…The authors uncover evidence that citizens' priorities about various spheres of legislative representation differ across demographic groups and that these…”
Get full text