Search Results - "GREY, Shane T"

Interleukin‐17A‐Induced Human Mesenchymal Stem Cells Are Superior Modulators of Immunological Function by Sivanathan, Kisha Nandini, Rojas‐Canales, Darling M., Hope, Christopher M., Krishnan, Ravi, Carroll, Robert P., Gronthos, Stan, Grey, Shane T., Coates, Patrick T.

“…Interferon‐γ (IFN‐γ)‐preactivated mesenchymal stem cells (MSC‐γ) are highly immunosuppressive but immunogenic in vivo due to their inherent expression of major…”
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RELA governs a network of islet-specific metabolic genes necessary for beta cell function by Zammit, Nathan W., Wong, Ying Ying, Walters, Stacey N., Warren, Joanna, Barry, Simon C., Grey, Shane T.

“…Aims/hypothesis NF-κB activation unites metabolic and inflammatory responses in many diseases yet less is known about the role that NF-κB plays in normal…”
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Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer by Chou, Angela, Froio, Danielle, Nagrial, Adnan M, Parkin, Ashleigh, Murphy, Kendelle J, Chin, Venessa T, Wohl, Dalia, Steinmann, Angela, Stark, Rhys, Drury, Alison, Walters, Stacey N, Vennin, Claire, Burgess, Andrew, Pinese, Mark, Chantrill, Lorraine A, Cowley, Mark J, Molloy, Timothy J, Waddell, Nicola, Johns, Amber, Grimmond, Sean M, Chang, David K, Biankin, Andrew V, Sansom, Owen J, Morton, Jennifer P, Grey, Shane T, Cox, Thomas R, Turchini, John, Samra, Jaswinder, Clarke, Stephen J, Timpson, Paul, Gill, Anthony J, Pajic, Marina

“…Extensive molecular heterogeneity of pancreatic ductal adenocarcinoma (PDA), few effective therapies and high mortality make this disease a prime model for…”
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Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells by Odorico, Jon, Markmann, James, Melton, Douglas, Greenstein, Julia, Hwa, Albert, Nostro, Cristina, Rezania, Alireza, Oberholzer, Jose, Pipeleers, Daniel, Yang, Luhan, Cowan, Chad, Huangfu, Danwei, Egli, Dieter, Ben-David, Uri, Vallier, Ludovic, Grey, Shane T, Tang, Qizhi, Roep, Bart, Ricordi, Camilo, Naji, Ali, Orlando, Giuseppe, Anderson, Daniel G, Poznansky, Mark, Ludwig, Barbara, Tomei, Alice, Greiner, Dale L, Graham, Melanie, Carpenter, Melissa, Migliaccio, Giovanni, D’Amour, Kevin, Hering, Bernhard, Piemonti, Lorenzo, Berney, Thierry, Rickels, Mike, Kay, Thomas, Adams, Ann

“…ABSTRACTBeta cell replacement has the potential to restore euglycemia in patients with insulin-dependent diabetes. Although great progress has been made in…”
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Editorial: Beta-Cell Fate: From Gene Circuits to Disease Mechanisms by Ghila, Luiza, Furuyama, Kenichiro, Grey, Shane T, Scholz, Hanne, Chera, Simona

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B cells as effectors and regulators of autoimmunity by Mariño, Eliana, Grey, Shane T.

“…A classic understanding of the interplay between B and T cell components of the immune system that drive autoimmunity, where B cells provide an effector…”
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MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD by Hsu, Alan C-Y, Dua, Kamal, Starkey, Malcolm R, Haw, Tatt-Jhong, Nair, Prema M, Nichol, Kristy, Zammit, Nathan, Grey, Shane T, Baines, Katherine J, Foster, Paul S, Hansbro, Philip M, Wark, Peter A

“…Influenza A virus (IAV) infections lead to severe inflammation in the airways. Patients with chronic obstructive pulmonary disease (COPD) characteristically…”
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TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation by Zammit, Nathan W, McDowell, Joseph, Warren, Joanna, Muskovic, Walter, Gamble, Joanne, Shi, Yan-Chuan, Kaczorowski, Dominik, Chan, Chia-Ling, Powell, Joseph, Ormandy, Chris, Brown, David, Oakes, Samantha R, Grey, Shane T

“…Women with autoimmune and inflammatory aetiologies can exhibit reduced fecundity. is a master negative regulator of inflammation, and has been linked to many…”
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Immunodepletion and Hypoxia Preconditioning of Mouse Compact Bone Cells as a Novel Protocol to Isolate Highly Immunosuppressive Mesenchymal Stem Cells by Sivanathan, Kisha Nandini, Gronthos, Stan, Grey, Shane T, Rojas-Canales, Darling, Coates, Patrick T

“…Compact bones (CB) are major reservoirs of mouse mesenchymal stem cells (mMSC). Here, we established a protocol to isolate MSC from CB and tested their…”
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Inhibition of Y1 receptor signaling improves islet transplant outcome by Loh, Kim, Shi, Yan-Chuan, Walters, Stacey, Bensellam, Mohammed, Lee, Kailun, Dezaki, Katsuya, Nakata, Masanori, Ip, Chi Kin, Chan, Jeng Yie, Gurzov, Esteban N., Thomas, Helen E., Waibel, Michaela, Cantley, James, Kay, Thomas W., Yada, Toshihiko, Laybutt, D. Ross, Grey, Shane T., Herzog, Herbert

“…Failure to secrete sufficient quantities of insulin is a pathological feature of type-1 and type-2 diabetes, and also reduces the success of islet cell…”
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A zebrafish functional genomics model to investigate the role of human A20 variants in vivo by Cultrone, Daniele, Zammit, Nathan W., Self, Eleanor, Postert, Benno, Han, Jeremy Z. R., Bailey, Jacqueline, Warren, Joanna, Croucher, David R., Kikuchi, Kazu, Bogdanovic, Ozren, Chtanova, Tatyana, Hesselson, Daniel, Grey, Shane T.

“…Germline loss-of-function variation in TNFAIP3 , encoding A20, has been implicated in a wide variety of autoinflammatory and autoimmune conditions, with…”
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Marginal-Zone B-Cells of Nonobese Diabetic Mice Expand With Diabetes Onset, Invade the Pancreatic Lymph Nodes, and Present Autoantigen to Diabetogenic T-Cells by Mariño, Eliana, Batten, Marcel, Groom, Joanna, Walters, Stacey, Liuwantara, David, Mackay, Fabienne, Grey, Shane T

“…Marginal-Zone B-Cells of Nonobese Diabetic Mice Expand With Diabetes Onset, Invade the Pancreatic Lymph Nodes, and Present Autoantigen to Diabetogenic T-Cells…”
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Transcriptome Profiling of IL-17A Preactivated Mesenchymal Stem Cells: A Comparative Study to Unmodified and IFN-γ Modified Mesenchymal Stem Cells by Sivanathan, Kisha Nandini, Rojas-Canales, Darling, Grey, Shane T., Gronthos, Stan, Coates, Patrick T.

“…Human mesenchymal stem cells pretreatment with IL-17A (MSC-17) potently enhances T cell immunosuppression but not their immunogenicity, in addition to avidly…”
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CD4+CD25+ T-Cells Control Autoimmunity in the Absence of B-Cells by MARINO, Eliana, VILLANUEVA, Jeanette, WALTERS, Stacey, LIUWANTARA, David, MACKAY, Fabienne, GREY, Shane T

“…CD4 + CD25 + T-Cells Control Autoimmunity in the Absence of B-Cells Eliana Mariño , Jeanette Villanueva , Stacey Walters , David Liuwantara , Fabienne Mackay…”
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PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells by Chandrakanthan, Vashe, Yeola, Avani, Kwan, Jair C., Oliver, Rema A., Qiao, Qiao, Kang, Young Chan, Zarzour, Peter, Beck, Dominik, Boelen, Lies, Unnikrishnan, Ashwin, Villanueva, Jeanette E., Nunez, Andrea C., Knezevic, Kathy, Palu, Cintia, Nasrallah, Rabab, Carnell, Michael, Macmillan, Alex, Whan, Renee, Yu, Yan, Hardy, Philip, Grey, Shane T., Gladbach, Amadeus, Delerue, Fabien, Ittner, Lars, Mobbs, Ralph, Walkley, Carl R., Purton, Louise E., Ward, Robyn L., Wong, Jason W. H., Hesson, Luke B., Walsh, William, Pimanda, John E.

“…Current approaches in tissue engineering are geared toward generating tissue-specific stem cells. Given the complexity and heterogeneity of tissues, this…”
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Desmoglein-2 is important for islet function and β-cell survival by Myo Min, Kay K., Rojas-Canales, Darling, Penko, Daniella, DeNichilo, Mark, Cockshell, Michaelia P., Ffrench, Charlie B., Thompson, Emma J., Asplund, Olof, Drogemuller, Christopher J., Prasad, Rashmi B., Groop, Leif, Grey, Shane T., Thomas, Helen E., Loudovaris, Thomas, Kay, Thomas W., Mahoney, My G., Jessup, Claire F., Coates, P. Toby, Bonder, Claudine S.

“…Type 1 diabetes is a complex disease characterized by the lack of endogenous insulin secreted from the pancreatic β-cells. Although β-cell targeted autoimmune…”
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Multispectral Imaging of Collagen, NAD(P)H and Flavin Autofluorescence in Mesenchymal Stem Cells Undergoing Trilineage Differentiation by Campbell, Jared M, Mahbub, Saabah B, Anwer, Ayad G, Habibalahi, Abbas, Gronthos, Stan, Paton, Sharon, Grey, Shane T, Wu, Lindsay E, Gilchrist, Robert B, Goldys, Ewa M

“…Understanding the molecular mechanisms of differentiation is important for regenerative medicine and developmental biology. This study aims to characterise the…”
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Pancreatic Islet Viability Assessment Using Hyperspectral Imaging of Autofluorescence by Campbell, Jared M, Walters, Stacey N, Habibalahi, Abbas, Mahbub, Saabah B, Anwer, Ayad G, Handley, Shannon, Grey, Shane T, Goldys, Ewa M

“…Islets prepared for transplantation into type 1 diabetes patients are exposed to compromising intrinsic and extrinsic factors that contribute to early graft…”
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Role for Activating Transcription Factor 3 in Stress-Induced β-Cell Apoptosis by Hartman, Matthew G., Lu, Dan, Kim, Mi-Lyang, Kociba, Gary J., Shukri, Tala, Buteau, Jean, Wang, Xiaozhong, Frankel, Wendy L., Guttridge, Denis, Prentki, Marc, Grey, Shane T., Ron, David, Hai, Tsonwin

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Automated pancreatic islet viability assessment for transplantation using bright-field deep morphological signature by Habibalahi, Abbas, Campbell, Jared M., Walters, Stacey N., Mahbub, Saabah B., Anwer, Ayad G., Grey, Shane T., Goldys, Ewa M.

“…Islets transplanted for type-1 diabetes have their viability reduced by warm ischemia, dimethyloxalylglycine (DMOG; hypoxia model), oxidative stress and…”
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