Search Results - "GRENETT, H. E"

Interaction of plasminogen with dipeptidyl peptidase IV initiates a signal transduction mechanism which regulates expression of matrix metalloproteinase-9 by prostate cancer cells by Gonzalez-Gronow, M, Grenett, H E, Weber, M R, Gawdi, G, Pizzo, S V

“…Both plasminogen (Pg) activation and matrix metalloproteinases (MMPs) are involved in the proteolytic degradation of extracellular matrix components, a…”
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Genotype-Specific Transcriptional Regulation of PAI-1 Expression by Hypertriglyceridemic VLDL and Lp(a) in Cultured Human Endothelial Cells by Li, Xin-Nong, Grenett, Hernan E, Benza, Raymond L, Demissie, Sossiena, Brown, Stephen L, Tabengwa, Edlue M, Gianturco, Sandra H, Bradley, William A, Fless, Gunther M, Booyse, Francois M

“…The hypothesized relationships between plasminogen activator inhibitor (PAI-1) genotypes, PAI-1 levels, and their potential regulation by hypertriglyceridemic…”
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Full-length cDNA for rabbit tryptophan hydroxylase: functional domains and evolution of aromatic amino acid hydroxylases by Grenett, H.E, Ledley, F.D, Reed, L.L, Woo, S.L.C

“…A full-length cDNA for tryptophan hydroxylase was cloned from rabbit pineal body by screening an expression library with antibody against rat phenylalanine…”
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Induction and regulation of interleukin-6 gene expression in rat astrocytes by Benveniste, E N, Sparacio, S M, Norris, J G, Grenett, H E, Fuller, G M

“…Cells that produce interleukin-6 (IL-6) require the presence of signaling molecules since this cytokine is not normally constitutively expressed. It is now…”
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Gene polymorphisms for plasminogen activator inhibitor-1/tissue plasminogen activator and development of allograft coronary artery disease by BENZA, R. L, GRENETT, H. E, BOURGE, R. C, KIRKLIN, J. K, NAFTEL, D. C, CASTRO, P. F, MCGIFFIN, D. C, GEORGE, J. F, BOOYSE, F. M

“…Impaired fibrinolytic activity has been linked to the presence and severity of allograft vasculopathy (Tx CAD). This impairment may be associated with the…”
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Ethanol Downregulates Transcription of the PAI-1 Gene in Cultured Human Endothelial Cells by Grenett, Hernan E, Aikens, Michael L, Tabengwa, Edlue M, Davis, Glenda C, Booyse, Francois M

“…Human endothelial cells are a major site of synthesis for plasminogen activator inhibitor type-1. Elevated plasminogen activator inhibitor type-1 levels in…”
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Quercetin induced tissue‐type plasminogen activator expression is mediated through Sp1 and p38 mitogen‐activated protein kinase in human endothelial cells by PAN, W., CHANG, M. J., BOOYSE, F. M., GRENETT, H. E., BRADLEY, K. M., WOLKOWICZ, P. E., SHANG, Q., TABENGWA, E. M.

“…Background: Wine polyphenol quercetin upregulates tissue‐type plasminogen activator (t‐PA) transcription in cultured human umbilical cord vein endothelial…”
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Genotype-Specific Transcriptional Regulation of PAI-1 Gene by Insulin, Hypertriglyceridemic VLDL, and Lp(a) in Transfected, Cultured Human Endothelial Cells by Grenett, Hernan E, Benza, Raymond L, Fless, Gunther M, Li, Xin-Nong, Davis, Glenda C, Booyse, Francois M

“…Plasminogen activator inhibitor-1 (PAI-1) has been shown to be an independent risk factor for coronary artery disease. Variations in plasma PAI-1 levels have…”
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Induction of matrix metalloproteinases and a collagen-degrading phenotype in fibroblasts and epithelial cells by secreted Porphyromonas gingivalis proteinase by DeCarlo, Arthur A., Grenett, Hernan E., Harber, Greg J., Windsor, L. Jack, Bodden, M. Kirby, Birkedal-Hansen, Bente, Birkedal-Hansen, Henning

“…Periodontitis is characterized by advancement of a narrow band of epithelium (1–10 cells wide) through the collagenous periodontal ligament in response to…”
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Ethanol Increases Surface-Localized Fibrinolytic Activity in Cultured Endothelial Cells by Aikens, Michael L., Benza, Raymond L., Grenett, Hernan E., Tabengwa, Edlue M., Davis, Glenda C., Demissie, Sossiena, Booyse, Francois M.

“…Epidemiological studies demonstrated a positive association between moderate alcohol consumption and reduced cardiovascular mortality that may be mediated, in…”
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Expression of plasminogen activator inhibitor type I in genotyped human endothelial cell cultures: genotype-specific regulation by insulin by Grenett, H E, Benza, R L, Li, X N, Aikens, M L, Grammer, J R, Brown, S L, Booyse, F M

“…Patients with non-insulin-dependent diabetes mellitus frequently have been associated with elevation in plasma levels of PAI-1. Part of the variations in…”
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Biochemical characterization of recombinant human phenylalanine hydroxylase produced in Escherichia coli by Ledley, F.D., Grenett, H.E., Woo, S.L.

“…A full-length human phenylalanine hydroxylase cDNA has been recombined with a prokaryotic expression vector and introduced into Escherichia coli. Transformed…”
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The Coordinated Regulation of Fibrinogen Gene Transcription by Hepatocyte-Stimulating Factor and Dexamethasone by Otto, James M., Grenett, Hernan E., Fuller, Gerald M.

“…Glucocorticoids and hepatocyte-stimulating factor (HSF; a monocyte/macrophage-derived polypeptide) are potent regulators of fibrinogen biosynthesis. Using…”
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Cloning and sequence analysis of the cDNA for murine interleukin-6 by GRENETT, H. E, FUENTES, N. L, FULLER, G. M

“…We isolated and sequenced a cDNA clone of murine interleukin-6 (mIL-6) from an activated murine macrophage library constructed in lambda gt11. This clone is…”
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Retroviral-Mediated Gene Transfer of Human Phenylalanine Hydroxylase into NIH 3T3 and Hepatoma Cells by Ledley, Fred D., Grenett, Hernan E., McGinnis-Shelnutt, Melanie, Savio L. C. Woo

“…Phenylketonuria (PKU) is caused by deficiency of the hepatic enzyme phenylalanine hydroxylase (PAH). A full-length human PAH cDNA sequence has been inserted…”
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Identification of a human cDNA with high homology to yeast omnipotent suppressor 45 by Grenett, H E, Bounelis, P, Fuller, G M

“…Omnipotent suppression is a well-established phenomenon in yeast and bacteria in which nonsense mutations are misread. Wild-type (wt) suppressors are presumed…”
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Ethanol Transcriptionally Upregulates t-PA and u-PA Gene Expression in Cultured Human Endothelial Cells by Grenett, Hernan E., Aikens, Michael L., Torres, Jose A., Demissie, Sossiena, Tabengwa, Edlue M., Davis, Glenda C., Booyse, Francois M.

“…Epidemiological studies have suggested that moderate alcohol consumption reduces the risk of cardiovascular mortality. This cardio‐protective benefit may be…”
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Gene Transfer and Expression of Human Phenylalanine Hydroxylase by Ledley, Fred D., Grenett, Hernan E., DiLella, Anthony G., Simon C. M. Kwok, Savio L. C. Woo

“…Phenylketonuria (PKU) is caused by a genetic deficiency of the enzyme phenylalanine hydroxylase (PAH). A full-length complementary DNA clone of human PAH was…”
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Alcohol-Induced Upregulation of Plasminogen Activators and Fibrinolytic Activity in Cultured Human Endothelial Cells by Aikens, Michael L, Grenett, Hernan E., Benza, Raymond L, Tabengwa, Edlue M., Davis, Glenda C., Booyse, Francois M.

“…Clinical studies suggest that moderate alcohol consumption may decrease the risk for coronary artery disease and myocardial infarction. This effect may be…”
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Expression of PAI-1, t-PA and u-PA in cultured human umbilical vein endothelial cells derived from racial groups by Frist, Steven T., Taylor, Herman A., Kirk, Katherine A., Grammer, J.Robert, Li, Xin-Nong, Grenett, Herman E., Booyse, Francois M.

“…To determine whether inherent fibrinolytic differences may exist in racial groups (black americans, BA vs. white americans, WA), 55 different individual…”
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