Search Results - "GREINER, Timothy"

Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue by Scott, David W., Wright, George W., Williams, P. Mickey, Lih, Chih-Jian, Walsh, William, Jaffe, Elaine S., Rosenwald, Andreas, Campo, Elias, Chan, Wing C., Connors, Joseph M., Smeland, Erlend B., Mottok, Anja, Braziel, Rita M., Ott, German, Delabie, Jan, Tubbs, Raymond R., Cook, James R., Weisenburger, Dennis D., Greiner, Timothy C., Glinsmann-Gibson, Betty J., Fu, Kai, Staudt, Louis M., Gascoyne, Randy D., Rimsza, Lisa M.

“…The assignment of diffuse large B-cell lymphoma into cell-of-origin (COO) groups is becoming increasingly important with the emergence of novel therapies that…”
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Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma by Heavican, Tayla B., Bouska, Alyssa, Yu, Jiayu, Lone, Waseem, Amador, Catalina, Gong, Qiang, Zhang, Weiwei, Li, Yuping, Dave, Bhavana J., Nairismägi, Maarja-Liisa, Greiner, Timothy C., Vose, Julie, Weisenburger, Dennis D., Lachel, Cynthia, Wang, Chao, Fu, Kai, Stevens, Jadd M., Lim, Soon Thye, Ong, Choon Kiat, Gascoyne, Randy D., Missiaglia, Edoardo, Lemonnier, Francois, Haioun, Corinne, Hartmann, Sylvia, Pedersen, Martin Bjerregård, Laginestra, Maria Antonella, Wilcox, Ryan A., Teh, Bin Tean, Yoshida, Noriaki, Ohshima, Koichi, Seto, Masao, Rosenwald, Andreas, Ott, German, Campo, Elias, Rimsza, Lisa M., Jaffe, Elaine S., Braziel, Rita M., d'Amore, Francesco, Inghirami, Giorgio, Bertoni, Francesco, de Leval, Laurence, Gaulard, Philippe, Staudt, Louis M., McKeithan, Timothy W., Pileri, Stefano, Chan, Wing C., Iqbal, Javeed

“…Peripheral T-cell lymphoma (PTCL) is a group of complex clinicopathological entities, often associated with an aggressive clinical course. Angioimmunoblastic…”
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Reproducing the molecular subclassification of peripheral T-cell lymphoma–NOS by immunohistochemistry by Amador, Catalina, Greiner, Timothy C., Heavican, Tayla B., Smith, Lynette M., Galvis, Karen Tatiana, Lone, Waseem, Bouska, Alyssa, D'Amore, Francesco, Pedersen, Martin Bjerregaard, Pileri, Stefano, Agostinelli, Claudio, Feldman, Andrew L., Rosenwald, Andreas, Ott, German, Mottok, Anja, Savage, Kerry J., de Leval, Laurence, Gaulard, Philippe, Lim, Soon Thye, Ong, Choon Kiat, Ondrejka, Sarah L., Song, Joo, Campo, Elias, Jaffe, Elaine S., Staudt, Louis M., Rimsza, Lisa M., Vose, Julie, Weisenburger, Dennis D., Chan, Wing C., Iqbal, Javeed

“…Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of mature T-cell malignancies; approximately one-third of cases are designated as PTCL–not otherwise…”
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Immunohistochemical Methods for Predicting Cell of Origin and Survival in Patients With Diffuse Large B-Cell Lymphoma Treated With Rituximab by MEYER, Paul N, KAI FU, VOSE, Julie M, LENZ, Georg, STAUDT, Louis M, CHAN, Wing C, WEISENBURGER, Dennis D, GREINER, Timothy C, SMITH, Lynette M, DELABIE, Jan, GASCOYNE, Randy D, OTT, German, ROSENWALD, Andreas, BRAZIEL, Rita M, CAMPO, Elias

“…Patients with diffuse large B-cell lymphoma (DLBCL) can be divided into prognostic groups based on the cell of origin of the tumor as determined by microarray…”
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Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome by Chigrinova, Ekaterina, Rinaldi, Andrea, Kwee, Ivo, Rossi, Davide, Rancoita, Paola M.V., Strefford, Jonathan C., Oscier, David, Stamatopoulos, Kostas, Papadaki, Theodora, Berger, Francoise, Young, Ken H., Murray, Fiona, Rosenquist, Richard, Greiner, Timothy C., Chan, Wing C., Orlandi, Ester M., Lucioni, Marco, Marasca, Roberto, Inghirami, Giorgio, Ladetto, Marco, Forconi, Francesco, Cogliatti, Sergio, Votavova, Hana, Swerdlow, Steven H., Stilgenbauer, Stephan, Piris, Miguel A., Matolcsy, Andras, Spagnolo, Dominic, Nikitin, Eugene, Zamò, Alberto, Gattei, Valter, Bhagat, Govind, Ott, German, Zucca, Emanuele, Gaidano, Gianluca, Bertoni, Francesco

“…Richter syndrome (RS) occurs in up to 15% of patients with chronic lymphocytic leukemia (CLL). Although RS, usually represented by the histologic…”
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Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma by Iqbal, Javeed, Wright, George, Wang, Chao, Rosenwald, Andreas, Gascoyne, Randy D., Weisenburger, Dennis D., Greiner, Timothy C., Smith, Lynette, Guo, Shuangping, Wilcox, Ryan A., Teh, Bin Tean, Lim, Soon Thye, Tan, Soon Yong, Rimsza, Lisa M., Jaffe, Elaine S., Campo, Elias, Martinez, Antonio, Delabie, Jan, Braziel, Rita M., Cook, James R., Tubbs, Raymond R., Ott, German, Geissinger, Eva, Gaulard, Philippe, Piccaluga, Pier Paolo, Pileri, Stefano A., Au, Wing Y., Nakamura, Shigeo, Seto, Masao, Berger, Francoise, de Leval, Laurence, Connors, Joseph M., Armitage, James, Vose, Julie, Chan, Wing C., Staudt, Louis M.

“…Peripheral T-cell lymphoma (PTCL) encompasses a heterogeneous group of neoplasms with generally poor clinical outcome. Currently 50% of PTCL cases are not…”
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Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma by Grande, Bruno M., Gerhard, Daniela S., Jiang, Aixiang, Griner, Nicholas B., Abramson, Jeremy S., Alexander, Thomas B., Allen, Hilary, Ayers, Leona W., Bethony, Jeffrey M., Bhatia, Kishor, Bowen, Jay, Casper, Corey, Choi, John Kim, Culibrk, Luka, Davidsen, Tanja M., Dyer, Maureen A., Gastier-Foster, Julie M., Gesuwan, Patee, Greiner, Timothy C., Gross, Thomas G., Hanf, Benjamin, Harris, Nancy Lee, He, Yiwen, Irvin, John D., Jaffe, Elaine S., Jones, Steven J.M., Kerchan, Patrick, Knoetze, Nicole, Leal, Fabio E., Lichtenberg, Tara M., Ma, Yussanne, Martin, Jean Paul, Martin, Marie-Reine, Mbulaiteye, Sam M., Mullighan, Charles G., Mungall, Andrew J., Namirembe, Constance, Novik, Karen, Noy, Ariela, Ogwang, Martin D., Omoding, Abraham, Orem, Jackson, Reynolds, Steven J., Rushton, Christopher K., Sandlund, John T., Schmitz, Roland, Taylor, Cynthia, Wilson, Wyndham H., Wright, George W., Zhao, Eric Y., Marra, Marco A., Morin, Ryan D., Staudt, Louis M.

“…Although generally curable with intensive chemotherapy in resource-rich settings, Burkitt lymphoma (BL) remains a deadly disease in older patients and in…”
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Transitioning From T-Cell Clonality Testing to High-Throughput Sequencing by Greiner, Timothy C, Bagg, Adam, Langerak, Anton W

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A New Immunostain Algorithm Classifies Diffuse Large B-Cell Lymphoma into Molecular Subtypes with High Accuracy by CHOI, William W. L, WEISENBURGER, Dennis D, VOSE, Julie M, HANS, Christine P, KAI FU, SMITH, Lynette M, MIN LI, ZHONGFENG LIU, GASCOYNE, Randy D, ROSENWALD, Andreas, OTT, German, RIMSZA, Lisa M, GREINER, Timothy C, CAMPO, Elias, JAFFE, Elaine S, JAYE, David L, STAUDT, Louis M, CHAN, Wing C, PIRIS, Miguel A, BANHAM, Alison H, DELABIE, Jan, BRAZIEL, Rita M, HUIMIN GENG, IQBAL, Javeed, LENZ, Georg

“…Purpose: Hans and coworkers previously developed an immunohistochemical algorithm with ∼80% concordance with the gene expression profiling (GEP)…”
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Frequency of MYD88 and CD79B mutations, and MGMT methylation in primary central nervous system diffuse large B‐cell lymphoma by Zheng, Mei, Perry, Anamarija M., Bierman, Philip, Loberiza, Fausto, Nasr, Michel R., Szwajcer, David, Del Bigio, Marc R., Smith, Lynette M., Zhang, Weiwei, Greiner, Timothy C.

“…Primary CNS diffuse large B‐cell lymphoma (PCNS‐DLBCL) and systemic DLBCL harbor mutations in MYD88 and CD79B. DNA methyltransferase (MGMT) is methylated in…”
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Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies by Xu-Monette, Zijun Y., Medeiros, L. Jeffrey, Li, Yong, Orlowski, Robert Z., Andreeff, Michael, Bueso-Ramos, Carlos E., Greiner, Timothy C., McDonnell, Timothy J., Young, Ken H.

“…Mutations of the TP53 gene and dysregulation of the TP53 pathway are important in the pathogenesis of many human cancers, including lymphomas. Tumor…”
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Gene Expression Signatures for the Accurate Diagnosis of Peripheral T-Cell Lymphoma Entities in the Routine Clinical Practice by Amador, Catalina, Bouska, Alyssa, Wright, George, Weisenburger, Dennis D, Feldman, Andrew L, Greiner, Timothy C, Lone, Waseem, Heavican, Tayla, Smith, Lynette, Pileri, Stefano, Tabanelli, Valentina, Ott, German, Rosenwald, Andreas, Savage, Kerry J, Slack, Graham, Kim, Won Seog, Hyeh, Young, Li, Yuping, Dong, Gehong, Song, Joo, Ondrejka, Sarah, Cook, James R, Barrionuevo, Carlos, Lim, Soon Thye, Ong, Choon Kiat, Chapman, Jennifer, Inghirami, Giorgio, Raess, Philipp W, Bhagavathi, Sharathkumar, Gould, Clare, Blombery, Piers, Jaffe, Elaine, Morris, Stephan W, Rimsza, Lisa M, Vose, Julie M, Staudt, Louis, Chan, Wing C, Iqbal, Javeed

“…Peripheral T-cell lymphoma (PTCL) includes heterogeneous clinicopathologic entities with numerous diagnostic and treatment challenges. We previously defined…”
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Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma by Iqbal, Javeed, Weisenburger, Dennis D., Greiner, Timothy C., Vose, Julie M., McKeithan, Timothy, Kucuk, Can, Geng, Huimin, Deffenbacher, Karen, Smith, Lynette, Dybkaer, Karen, Nakamura, Shigeo, Seto, Masao, Delabie, Jan, Berger, Francoise, Loong, Florence, Au, Wing Y., Ko, Young-Hyeh, Sng, Ivy, Armitage, James Olen, Chan, Wing C.

“…Peripheral T-cell lymphoma (PTCL) is often challenging to diagnose and classify. Gene expression profiling was performed on 144 cases of PTCL and natural…”
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Addition of Rituximab to Standard Chemotherapy Improves the Survival of Both the Germinal Center B-Cell–Like and Non–Germinal Center B-Cell–Like Subtypes of Diffuse Large B-Cell Lymphoma by KAI FU, WEISENBURGER, Dennis D, ARMITAGE, James O, CHAN, Wing C, VOSE, Julie M, CHOI, William W. L, PERRY, Kyle D, SMITH, Lynette M, XINLAN SHI, HANS, Christine P, GREINER, Timothy C, BIERMAN, Philip J, BOCIEK, R. Gregory

“…Diffuse large B-cell lymphoma (DLBCL) includes at least two prognostically important subtypes (ie, germinal center B-cell-like [GCB] and activated B-cell-like…”
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MYC and BCL2 protein expression predicts survival in patients with diffuse large B‐cell lymphoma treated with rituximab by Perry, Anamarija M., Alvarado‐Bernal, Yuridia, Laurini, Javier A., Smith, Lynette M., Slack, Graham W., Tan, King L., Sehn, Laurie H., Fu, Kai, Aoun, Patricia, Greiner, Timothy C., Chan, Wing C., Bierman, Philip J., Bociek, Robert G., Armitage, James O., Vose, Julie M., Gascoyne, Randy D., Weisenburger, Dennis D.

“…Summary Diffuse large B‐cell lymphoma (DLBCL) is a heterogeneous disease and “double‐hit” DLBCL, with both MYC and BCL2 translocations has a poor prognosis. In…”
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Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma by Ma, Man Chun John, Tadros, Saber, Bouska, Alyssa, Heavican, Tayla, Yang, Haopeng, Deng, Qing, Moore, Dalia, Akhter, Ariz, Hartert, Keenan, Jain, Neeraj, Showell, Jordan, Ghosh, Sreejoyee, Street, Lesley, Davidson, Marta, Carey, Christopher, Tobin, Joshua, Perumal, Deepak, Vose, Julie M, Lunning, Matthew A, Sohani, Aliyah R, Chen, Benjamin J, Buckley, Shannon, Nastoupil, Loretta J, Davis, R Eric, Westin, Jason R, Fowler, Nathan H, Parekh, Samir, Gandhi, Maher, Neelapu, Sattva, Stewart, Douglas, Bhalla, Kapil, Iqbal, Javeed, Greiner, Timothy, Rodig, Scott J, Mansoor, Adnan, Green, Michael R

“…B-cell non-Hodgkin lymphoma (B-NHL) encompasses multiple clinically and phenotypically distinct subtypes of malignancy with unique molecular etiologies. Common…”
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New Molecular Assay for the Proliferation Signature in Mantle Cell Lymphoma Applicable to Formalin-Fixed Paraffin-Embedded Biopsies by Scott, David W, Abrisqueta, Pau, Wright, George W, Slack, Graham W, Mottok, Anja, Villa, Diego, Jares, Pedro, Rauert-Wunderlich, Hilka, Royo, Cristina, Clot, Guillem, Pinyol, Magda, Boyle, Merrill, Chan, Fong Chun, Braziel, Rita M, Chan, Wing C, Weisenburger, Dennis D, Cook, James R, Greiner, Timothy C, Fu, Kai, Ott, German, Delabie, Jan, Smeland, Erlend B, Holte, Harald, Jaffe, Elaine S, Steidl, Christian, Connors, Joseph M, Gascoyne, Randy D, Rosenwald, Andreas, Staudt, Louis M, Campo, Elias, Rimsza, Lisa M

“…Purpose Mantle cell lymphoma is an aggressive B-cell neoplasm that displays heterogeneous outcomes after treatment. In 2003, the Lymphoma/Leukemia Molecular…”
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Radiologic Differentiation of Primary CNS Posttransplant Lymphoproliferative Disorder From Brain Metastasis by White, Matthew L, Zhang, Yan, Cramer, Justin, Yu, Fang, Bierman, Philip J, Greiner, Timothy C

“…Primary CNS posttransplant lymphoproliferative disorder (PTLD) may present as multiple contrast-enhancing intraaxial lesions, often with central necrosis and…”
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DNMT3A mutations define a unique biological and prognostic subgroup associated with cytotoxic T cells in PTCL-NOS by Herek, Tyler A, Bouska, Alyssa, Lone, Waseem, Sharma, Sunandini, Amador, Catalina, Heavican, Tayla B, Li, Yuping, Wei, Qi, Jochum, Dylan, Greiner, Timothy C, Smith, Lynette, Pileri, Stefano, Feldman, Andrew L, Rosenwald, Andreas, Ott, German, Lim, Soon Thye, Ong, Choon Kiat, Song, Joo, Jaffe, Elaine S, Wang, Gang Greg, Staudt, Louis, Rimsza, Lisa M, Vose, Julie, d'Amore, Francesco, Weisenburger, Dennis D, Chan, Wing C, Iqbal, Javeed

“…Peripheral T-cell lymphomas (PTCLs) are heterogenous T-cell neoplasms often associated with epigenetic dysregulation. We investigated de novo DNA…”
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Activation of the STAT3 Signaling Pathway Is Associated With Poor Survival in Diffuse Large B-Cell Lymphoma Treated With R-CHOP by Huang, Xin, Meng, Bin, Iqbal, Javeed, Ding, B Belinda, Perry, Anamarija M, Cao, Wenfeng, Smith, Lynette M, Bi, Chengfeng, Jiang, Chunsun, Greiner, Timothy C, Weisenburger, Dennis D, Rimsza, Lisa, Rosenwald, Andreas, Ott, German, Delabie, Jan, Campo, Elias, Braziel, Rita M, Gascoyne, Randy D, Cook, James R, Tubbs, Raymond R, Jaffe, Elaine S, Armitage, James O, Vose, Julie M, Staudt, Louis M, McKeithan, Timothy W, Chan, Wing C, Ye, B Hilda, Fu, Kai

“…We previously reported that constitutive STAT3 activation is a prominent feature of the activated B-cell subtype of diffuse large B-cell lymphomas (ABC-DLBCL)…”
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