Search Results - "GREENWAY, Frank L"

A healthy gastrointestinal microbiome is dependent on dietary diversity by Heiman, Mark L, Greenway, Frank L

“…Abstract Like all healthy ecosystems, richness of microbiota species characterizes the GI microbiome in healthy individuals. Conversely, a loss in species…”
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Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial by Greenway, Frank L, Prof, Fujioka, Ken, MD, Plodkowski, Raymond A, Prof, Mudaliar, Sunder, Prof, Guttadauria, Maria, MD, Erickson, Janelle, PhD, Kim, Dennis D, MD, Dunayevich, Eduardo, MD

“…Summary Background Despite increasing public health concerns regarding obesity, few safe and effective drug treatments are available. Combination treatment…”
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Effect of time restricted eating on body weight and fasting glucose in participants with obesity: results of a randomized, controlled, virtual clinical trial by Peeke, Pamela M., Greenway, Frank L., Billes, Sonja K., Zhang, Dachuan, Fujioka, Ken

“…Background Time restricted eating (TRE) is an emerging dietary intervention for weight loss that is hypothesized to reinforce the metabolic benefits of nightly…”
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Leptin Mediates the Increase in Blood Pressure Associated with Obesity by Simonds, Stephanie E., Pryor, Jack T., Ravussin, Eric, Greenway, Frank L., Dileone, Ralph, Allen, Andrew M., Bassi, Jaspreet, Elmquist, Joel K., Keogh, Julia M., Henning, Elana, Myers, Martin G., Licinio, Julio, Brown, Russell D., Enriori, Pablo J., O’Rahilly, Stephen, Sternson, Scott M., Grove, Kevin L., Spanswick, David C., Farooqi, I. Sadaf, Cowley, Michael A.

“…Obesity is associated with increased blood pressure (BP), which in turn increases the risk of cardiovascular diseases. We found that the increase in leptin…”
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The Relationship of Waist Circumference and BMI to Visceral, Subcutaneous, and Total Body Fat: Sex and Race Differences by Camhi, Sarah M., Bray, George A., Bouchard, Claude, Greenway, Frank L., Johnson, William D., Newton, Robert L., Ravussin, Eric, Ryan, Donna H., Smith, Steven R., Katzmarzyk, Peter T.

“…The purpose of this study was to examine sex and race differences in the relationship between anthropometric measurements and adiposity in white and…”
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Safety and pharmacokinetics of naringenin: A randomized, controlled, single‐ascending‐dose clinical trial by Rebello, Candida J., Beyl, Robbie A., Lertora, Juan J. L., Greenway, Frank L., Ravussin, Eric, Ribnicky, David M., Poulev, Alexander, Kennedy, Brandon J., Castro, Hector F., Campagna, Shawn R., Coulter, Ann A., Redman, Leanne M.

“…Aims To evaluate the safety and pharmacokinetics of naringenin in healthy adults consuming whole‐orange (Citrus sinensis) extract. Methods and methods In a…”
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Selective sodium-dependent glucose transporter 1 inhibitors block glucose absorption and impair glucose-dependent insulinotropic peptide release by Dobbins, Robert L, Greenway, Frank L, Chen, Lihong, Liu, Yaping, Breed, Sharon L, Andrews, Susan M, Wald, Jeffrey A, Walker, Ann, Smith, Chari D

“…GSK-1614235 and KGA-2727 are potent, selective inhibitors of the SGLT1 sodium-dependent glucose transporter. Nonclinical (KGA-2727) and clinical (GSK-1614235)…”
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Naringenin Increases Insulin Sensitivity and Metabolic Rate: A Case Study by Murugesan, Navya, Woodard, Kaylee, Ramaraju, Rahul, Greenway, Frank L, Coulter, Ann A, Rebello, Candida J

“…Our studies in primary human adipocytes show that naringenin, a citrus flavonoid, increases oxygen consumption rate and gene expression of uncoupling protein 1…”
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Low-Energy Dense Potato- and Bean-Based Diets Reduce Body Weight and Insulin Resistance: A Randomized, Feeding, Equivalence Trial by Rebello, Candida J, Beyl, Robbie A, Greenway, Frank L, Atteberry, Kelly C, Hoddy, Kristin K, Kirwan, John P

“…We evaluated the effect of diets low in energy density (1 kcal/g) and high in either potatoes (Potato) or pulses (Bean) on blood glucose control in…”
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The Personalized Nutrition Study (POINTS): evaluation of a genetically informed weight loss approach, a Randomized Clinical Trial by Höchsmann, Christoph, Yang, Shengping, Ordovás, José M., Dorling, James L., Champagne, Catherine M., Apolzan, John W., Greenway, Frank L., Cardel, Michelle I., Foster, Gary D., Martin, Corby K.

“…Weight loss (WL) differences between isocaloric high-carbohydrate and high-fat diets are generally small; however, individual WL varies within diet groups…”
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Rational Design of a Combination Medication for the Treatment of Obesity by Greenway, Frank L., Whitehouse, M.J., Guttadauria, Maria, Anderson, James W., Atkinson, Richard L., Fujioka, Ken, Gadde, Kishore M., Gupta, Alok K., O'Neil, Patrick, Schumacher, Donald, Smith, Diane, Dunayevich, Eduardo, Tollefson, Gary D., Weber, Eckard, Cowley, Michael A.

“…Existing obesity therapies are limited by safety concerns and modest efficacy reflecting a weight loss plateau. Here, we explore combination therapy with…”
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Editorial: Stress-induced weight changes by Heshmati, Hassan M, Luzi, Livio, Greenway, Frank L, Rebello, Candida J

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Measuring ketone bodies for the monitoring of pathologic and therapeutic ketosis by Anderson, Joseph C., Mattar, Samer G., Greenway, Frank L., Lindquist, Richard J.

“…Background The ketone bodies β‐hydroxybutyrate (BOHB) and acetone are generated as a byproduct of the fat metabolism process. In healthy individuals, ketone…”
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Mechanism for the Increase in Human Growth Hormone with Administration of a Novel Test Supplement and Results Indicating Improved Physical Fitness and Sleep Efficiency by Heaton, Amy L, Kelly, Colleen, Rood, Jennifer, Tam, Charmaine S, Greenway, Frank L

“…An oral test supplement increases serum human growth hormone (hGH) levels after acute administration in healthy adults. We investigated the mechanism for the…”
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Naringenin and β-carotene convert human white adipocytes to a beige phenotype and elevate hormone- stimulated lipolysis by Coulter, Ann A, Greenway, Frank L, Zhang, Dachuan, Ghosh, Sujoy, Coulter, Cathryn R, James, Sarah L, He, Yanlin, Cusimano, Luke A, Rebello, Candida J

“…Naringenin, a peroxisome proliferator-activated receptor (PPAR) activator found in citrus fruits, upregulates markers of thermogenesis and insulin sensitivity…”
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Prehypertension in disease-free adults: a marker for an adverse cardiometabolic risk profile by Gupta, Alok K, McGlone, Meghan, Greenway, Frank L, Johnson, William D

“…Cardiovascular disease (CVD) is the leading cause of death worldwide. Understandably, cardiometabolic risk assessment is an integral component of every adult…”
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Obesity and Albuminuria Among Adults With Type 2 Diabetes: The Look AHEAD (Action for Health in Diabetes) Study by Kramer, Holly, Reboussin, David, Bertoni, Alain G, Marcovina, Santica, Lipkin, Edward, Greenway, Frank L. III, Brancati, Frederick L

“…OBJECTIVE: To determine the association between obesity measures and albuminuria in adults with type 2 diabetes. RESEARCH DESIGN AND METHODS: In the Look AHEAD…”
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Safety and Tolerability of Whole Soybean Products: A Dose-Escalating Clinical Trial in Older Adults with Obesity by Rebello, Candida J, Boué, Stephen, Levy, Jr, Ronald J, Puyau, Renée, Beyl, Robbie A, Greenway, Frank L, Heiman, Mark L, Keller, Jeffrey N, Reynolds, 3rd, Charles F, Kirwan, John P

“…Soybean products have nutrients, dietary fiber, and phytoalexins beneficial for cardiovascular and overall health. Despite their high consumption in Asian…”
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Polytetrafluoroethylene Ingestion as a Way to Increase Food Volume and Hence Satiety Without Increasing Calorie Content by Naftalovich, Rotem, Naftalovich, Daniel, Greenway, Frank L.

“…Since satiety is largely due to stretch of the stomach and people tend to eat a consistent weight of food, increasing food volume and mass increases satiety…”
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MLR-1023 Treatment in Mice and Humans Induces a Thermogenic Program, and Menthol Potentiates the Effect by Rebello, Candida J, Coulter, Ann A, Reaume, Andrew G, Cong, Weina, Cusimano, Luke A, Greenway, Frank L

“…A glucose-lowering medication that acts by a different mechanism than metformin, or other approved diabetes medications, can supplement monotherapies when…”
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