Search Results - "GREENLAND, John"
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COVID-19 Infection: Implications for Perioperative and Critical Care Physicians
Published in Anesthesiology (Philadelphia) (01-06-2020)“…Healthcare systems worldwide are responding to Coronavirus Disease 2019 (COVID-19), an emerging infectious syndrome caused by the Severe Acute Respiratory…”
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Transcriptome-based diagnostics for chronic lung allograft dysfunction: A socratic question revisited
Published in The Journal of heart and lung transplantation (01-12-2020)Get full text
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Where the Chromosome Ends: Telomeres and Cytomegalovirus Risk in Lung Transplant Recipients
Published in American journal of respiratory and critical care medicine (01-02-2019)“…Telomere dysfunction is well described as a cause of idiopathic pulmonary fibrosis (IPF), and shortened telomeres have also been linked with other lung…”
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HLA-G/ILT2 signaling on the path to tolerance
Published in The Journal of heart and lung transplantation (01-06-2022)Get full text
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Natural killer cells in lung transplantation
Published in Thorax (01-04-2019)“…Natural killer (NK) cells are innate lymphoid cells that have been increasingly recognised as important in lung allograft tolerance and immune defence. These…”
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The lung transplant endobronchial biopsy: A forgotten specimen comes of age
Published in The Journal of heart and lung transplantation (28-10-2024)“…Mucosal or endobronchial biopsies (EBB) are typically used in the diagnosis of directly visualized bronchial lesions, infection, and sarcoidosis, but their…”
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Theseus and the search for an antibody-mediated rejection molecular state in lung transplant biopsies
Published in American journal of transplantation (01-12-2023)Get full text
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Frailty trajectories in adult lung transplantation: A cohort study
Published in The Journal of heart and lung transplantation (01-07-2019)“…Frailty is common in adults with advanced lung disease and is associated with death before and after lung transplantation. We aimed to determine whether…”
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Chronic Lung Allograft Dysfunction
Published in Thoracic surgery clinics (01-05-2022)“…Chronic lung allograft dysfunction (CLAD) is a syndrome of progressive lung function decline, subcategorized into obstructive, restrictive, and mixed…”
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Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression
Published in The Journal of clinical investigation (01-04-2022)“…Platelets have a wide range of functions including critical roles in hemostasis, thrombosis, and immunity. We hypothesized that during acute inflammation, such…”
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Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression
Published in The Journal of experimental medicine (07-11-2022)“…Human adaptive-like natural killer (NK) cells express low levels of FcεRIγ (FcRγ-/low) and are reported to accumulate during COVID-19 infection; however, the…”
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Airway Epithelial Telomere Dysfunction Drives Remodeling Similar to Chronic Lung Allograft Dysfunction
Published in American journal of respiratory cell and molecular biology (01-10-2020)“…Telomere dysfunction is associated with multiple fibrotic lung processes, including chronic lung allograft dysfunction (CLAD)-the major limitation to long-term…”
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Molecular diagnostics for CLAD: When and where?
Published in American journal of transplantation (01-04-2022)“…While the Parkes et. al study (page 1054) adds to excitement about molecular diagnostics for chronic lung allograft dysfunction, questions remain as to how…”
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Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19
Published in Science translational medicine (22-09-2021)“…Neutralizing autoantibodies against type I interferons (IFNs) have been found in some patients with critical coronavirus disease 2019 (COVID-19), the disease…”
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Frailty phenotypes and mortality after lung transplantation: A prospective cohort study
Published in American journal of transplantation (01-08-2018)“…Frailty is associated with increased mortality among lung transplant candidates. We sought to determine the association between frailty, as measured by the…”
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The 2022 Banff Meeting Lung Report
Published in American journal of transplantation (01-04-2024)“…The Lung Session of the 2022 16th Banff Foundation for Allograft Pathology Conference—held in Banff, Alberta—focused on non-rejection lung allograft pathology…”
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Lymphocytic Airway Inflammation in Lung Allografts
Published in Frontiers in immunology (12-07-2022)“…Lung transplant remains a key therapeutic option for patients with end stage lung disease but short- and long-term survival lag other solid organ transplants…”
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Pathobiology of frailty in lung disease
Published in Translational research : the journal of laboratory and clinical medicine (01-07-2020)“…Frailty is a clinical state of vulnerability to stressors resulting from cumulative alterations in multiple physiological and molecular systems. Frailty…”
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Frailty and aging‐associated syndromes in lung transplant candidates and recipients
Published in American journal of transplantation (01-06-2021)“…Many lung transplant candidates and recipients are older and frailer compared to previous eras. Older patients are at increased risk for pre‐ and…”
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Development and Preliminary Validation of the Lung Transplant Quality of Life (LT-QOL) Survey
Published in American journal of respiratory and critical care medicine (15-04-2019)“…Although lung transplantation aims to improve health-related quality of life (HRQL), existing instruments fail to include health domains considered important…”
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