Search Results - "GREENHAW, James J"

Regorafenib impairs mitochondrial functions, activates AMP-activated protein kinase, induces autophagy, and causes rat hepatocyte necrosis by Weng, Zuquan, Luo, Yong, Yang, Xi, Greenhaw, James J, Li, Haibo, Xie, Liming, Mattes, William B, Shi, Qiang

“…Highlights • Regorafenib uncouples hepatic mitochondrial oxidative phosphorylation. • Regorafenib causes necrosis but not apoptosis in hepatocytes. •…”
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Hepatic Transcript Profiles of Cytochrome P450 Genes Predict Sex Differences in Drug Metabolism by Fuscoe, James C, Vijay, Vikrant, Hanig, Joseph P, Han, Tao, Ren, Lijun, Greenhaw, James J, Beger, Richard D, Pence, Lisa M, Shi, Qiang

“…Safety assessments of new drug candidates are an important part of the drug development and approval process. Often, possible sex-associated susceptibilities…”
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Drug-Induced Liver Injury in Children: Clinical Observations, Animal Models, and Regulatory Status by Shi, Qiang, Yang, Xi, Greenhaw, James J., Salminen, Alec Thomas, Russotti, Gary M., Salminen, William F.

“…Drug-induced liver injury in children (cDILI) accounts for about 1% of all reported adverse drug reactions throughout all age groups, less than 10% of all…”
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Novel Resuscitation Strategy for Pulmonary Contusion after Severe Chest Trauma by Kelly, Michael E., Miller, Preston R., Greenhaw, James J., Fabian, Timothy C., Proctor, Kenneth G.

“…BACKGROUND: METHODS: RESULTS:Fluid requirements were reduced by half with Hextend compared with LR (p < 0.05). ATL-146e in either Hextend or LR transiently…”
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Macrophage Cyclooxygenase Expression, Immunosuppression, and Cardiopulmonary Dysfunction after Blunt Chest Trauma by Desselle, Wesley J., Greenhaw, James J., Trenthem, Lisa L., Fabian, Timothy C., Proctor, Kenneth G.

“…BACKGROUNDTwo series of experiments were performed in swine who received severe blunt chest trauma. The goals were to determine the time course of constitutive…”
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Macrophage cyclooxygenase expression, immunosuppression, and cardiopulmonary dysfunction after blunt chest trauma. Discussion by DESSELLE, Wesley J, GREENHAW, James J, TRENTHEM, Lisa L, FABIAN, Timothy C, PROCTOR, Kenneth G, HAISCH, Carl E, HAUSER, Carl J

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Pectoral Glands of Scaphiopus and Megophrys by Jacob, James S., Greenhaw, James J., Plummer, Michael V., Gay, Jo M.

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