Search Results - "GREEN, Stefan J"

Deconstructing the polymerase chain reaction: understanding and correcting bias associated with primer degeneracies and primer-template mismatches by Green, Stefan J, Venkatramanan, Raghavee, Naqib, Ankur

“…The polymerase chain reaction (PCR) is sensitive to mismatches between primer and template, and mismatches can lead to inefficient amplification of targeted…”
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Massively parallel rRNA gene sequencing exacerbates the potential for biased community diversity comparisons due to variable library sizes by Gihring, Thomas M., Green, Stefan J., Schadt, Christopher W.

“…Summary Technologies for massively parallel sequencing are revolutionizing microbial ecology and are vastly increasing the scale of ribosomal RNA (rRNA) gene…”
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Colonic bacterial composition in Parkinson's disease by Keshavarzian, Ali, Green, Stefan J., Engen, Phillip A., Voigt, Robin M., Naqib, Ankur, Forsyth, Christopher B., Mutlu, Ece, Shannon, Kathleen M.

“…Introduction We showed that Parkinson's disease (PD) patients have alpha‐synuclein (α‐Syn) aggregation in their colon with evidence of colonic inflammation. If…”
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Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice by Ilievski, Vladimir, Zuchowska, Paulina K, Green, Stefan J, Toth, Peter T, Ragozzino, Michael E, Le, Khuong, Aljewari, Haider W, O'Brien-Simpson, Neil M, Reynolds, Eric C, Watanabe, Keiko

“…The results from cross sectional and longitudinal studies show that periodontitis is closely associated with cognitive impairment (CI) and Alzhemer's Disease…”
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Niche and host-associated functional signatures of the root surface microbiome by Ofek-Lalzar, Maya, Sela, Noa, Goldman-Voronov, Milana, Green, Stefan J., Hadar, Yitzhak, Minz, Dror

“…Plant microbiomes are critical to host adaptation and impact plant productivity and health. Root-associated microbiomes vary by soil and host genotype, but the…”
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Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice by Perez-Pardo, Paula, Dodiya, Hemraj B, Engen, Phillip A, Forsyth, Christopher B, Huschens, Andrea M, Shaikh, Maliha, Voigt, Robin M, Naqib, Ankur, Green, Stefan J, Kordower, Jeffrey H, Shannon, Kathleen M, Garssen, Johan, Kraneveld, Aletta D, Keshavarzian, Ali

“…Recent evidence suggesting an important role of gut-derived inflammation in brain disorders has opened up new directions to explore the possible role of the…”
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Circadian disorganization alters intestinal microbiota by Voigt, Robin M, Forsyth, Christopher B, Green, Stefan J, Mutlu, Ece, Engen, Phillip, Vitaterna, Martha H, Turek, Fred W, Keshavarzian, Ali

“…Intestinal dysbiosis and circadian rhythm disruption are associated with similar diseases including obesity, metabolic syndrome, and inflammatory bowel…”
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Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease by Dodiya, Hemraj B., Forsyth, Christopher B., Voigt, Robin M., Engen, Phillip A., Patel, Jinal, Shaikh, Maliha, Green, Stefan J., Naqib, Ankur, Roy, Avik, Kordower, Jeffrey H., Pahan, Kalipada, Shannon, Kathleen M., Keshavarzian, Ali

“…Recent evidence provides support for involvement of the microbiota-gut-brain axis in Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory…”
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Hydrocarbon-Degrading Bacteria and the Bacterial Community Response in Gulf of Mexico Beach Sands Impacted by the Deepwater Horizon Oil Spill by KOSTKA, Joel E, PRAKASH, Om, OVERHOLT, Will A, GREEN, Stefan J, FREYER, Gina, CANION, Andy, DELGARDIO, Jonathan, NORTON, Nikita, HAZEN, Terry C, HUETTEL, Markus

“…OA  Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Burn Injury Alters the Intestinal Microbiome and Increases Gut Permeability and Bacterial Translocation by Earley, Zachary M, Akhtar, Suhail, Green, Stefan J, Naqib, Ankur, Khan, Omair, Cannon, Abigail R, Hammer, Adam M, Morris, Niya L, Li, Xiaoling, Eberhardt, Joshua M, Gamelli, Richard L, Kennedy, Richard H, Choudhry, Mashkoor A

“…Sepsis remains one of the leading causes of death in burn patients who survive the initial insult of injury. Disruption of the intestinal epithelial barrier…”
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Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer by Aissa, Alexandre F., Islam, Abul B. M. M. K., Ariss, Majd M., Go, Cammille C., Rader, Alexandra E., Conrardy, Ryan D., Gajda, Alexa M., Rubio-Perez, Carlota, Valyi-Nagy, Klara, Pasquinelli, Mary, Feldman, Lawrence E., Green, Stefan J., Lopez-Bigas, Nuria, Frolov, Maxim V., Benevolenskaya, Elizaveta V.

“…Tyrosine kinase inhibitors were found to be clinically effective for treatment of patients with certain subsets of cancers carrying somatic mutations in…”
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Multi-amplicon microbiome data analysis pipelines for mixed orientation sequences using QIIME2: Assessing reference database, variable region and pre-processing bias in classification of mock bacterial community samples by Maki, Katherine A, Wolff, Brian, Varuzza, Leonardo, Green, Stefan J, Barb, Jennifer J

“…Microbiome research relies on next-generation sequencing and on downstream data analysis workflows. Several manufacturers have introduced multi-amplicon kits…”
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Gut microbiota varies by opioid use, circulating leptin and oxytocin in African American men with diabetes and high burden of chronic disease by Barengolts, Elena, Green, Stefan J, Eisenberg, Yuval, Akbar, Arfana, Reddivari, Bharathi, Layden, Brian T, Dugas, Lara, Chlipala, George

“…The gut microbiota is known to be related to type 2 diabetes (T2D), psychiatric conditions, and opioid use. In this study, we tested the hypothesis that…”
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Dietary inulin alters the gut microbiome, enhances systemic metabolism and reduces neuroinflammation in an APOE4 mouse model by Hoffman, Jared D, Yanckello, Lucille M, Chlipala, George, Hammond, Tyler C, McCulloch, Scott D, Parikh, Ishita, Sun, Sydney, Morganti, Josh M, Green, Stefan J, Lin, Ai-Ling

“…The apolipoprotein ε4 allele (APOE4) is the strongest genetic risk factor for Alzheimer's disease (AD). APOE4 carriers develop systemic metabolic dysfunction…”
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APOE genetics influence murine gut microbiome by Zajac, Diana J., Green, Stefan J., Johnson, Lance A., Estus, Steven

“…Apolipoprotein E ( APOE ) alleles impact pathogenesis and risk for multiple human diseases, making them primary targets for disease treatment and prevention…”
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Taxa-specific changes in soil microbial community composition induced by pyrogenic carbon amendments by Khodadad, Christina L.M., Zimmerman, Andrew R., Green, Stefan J., Uthandi, Sivakumar, Foster, Jamie S.

“…The effects of pyrogenic carbon on the microbial diversity of forest soils were examined by comparing two soil types, fire-impacted and non-impacted, that were…”
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Reproducible changes in the gut microbiome suggest a shift in microbial and host metabolism during spaceflight by Jiang, Peng, Green, Stefan J, Chlipala, George E, Turek, Fred W, Vitaterna, Martha Hotz

“…Space environment imposes a range of challenges to mammalian physiology and the gut microbiota, and interactions between the two are thought to be important in…”
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The Circadian Clock Mutation Promotes Intestinal Dysbiosis by Voigt, Robin M., Summa, Keith C., Forsyth, Christopher B., Green, Stefan J., Engen, Phillip, Naqib, Ankur, Vitaterna, Martha H., Turek, Fred W., Keshavarzian, Ali

“…Background Circadian rhythm disruption is a prevalent feature of modern day society that is associated with an increase in pro‐inflammatory diseases, and there…”
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An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson’s disease participants by Hall, Deborah A., Voigt, Robin M., Cantu-Jungles, Thaisa M., Hamaker, Bruce, Engen, Phillip A., Shaikh, Maliha, Raeisi, Shohreh, Green, Stefan J., Naqib, Ankur, Forsyth, Christopher B., Chen, Tingting, Manfready, Richard, Ouyang, Bichun, Rasmussen, Heather E., Sedghi, Shahriar, Goetz, Christopher G., Keshavarzian, Ali

“…A pro-inflammatory intestinal microbiome is characteristic of Parkinson’s disease (PD). Prebiotic fibers change the microbiome and this study sought to…”
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Human milk oligosaccharides protect against the development of autoimmune diabetes in NOD-mice by Xiao, Ling, van’t Land, Belinda, Engen, Phillip A., Naqib, Ankur, Green, Stefan J., Nato, Angie, Leusink-Muis, Thea, Garssen, Johan, Keshavarzian, Ali, Stahl, Bernd, Folkerts, Gert

“…Development of Type 1 diabetes (T1D) is influenced by non-genetic factors, such as optimal microbiome development during early life that “programs” the immune…”
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