Search Results - "GRAY, O. M"

A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis by STEIN, M. S, LIU, Y, KILPATRICK, T. J, GRAY, O. M, BAKER, J. E, KOLBE, S. C, DITCHFIELD, M. R, EGAN, G. F, MITCHELL, P. J, HARRISON, L. C, BUTZKUEVEN, H

“…Higher latitude, lower ultraviolet exposure, and lower serum 25-hydroxyvitamin D (25OHD) correlate with higher multiple sclerosis (MS) prevalence, relapse…”
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Factors in the rising prevalence of multiple sclerosis in the north-east of Ireland by Gray, OM, McDonnell, GV, Hawkins, SA

“…Background Northern Ireland is recognized as an area of high risk for multiple sclerosis. The original study of Allison and Millar in 1951 found a prevalence…”
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OPSOCLONUS-MYOCLONUS SYNDROME ASSOCIATED WITH BENIGN OVARIAN TERATOMA by FITZPATRICK, A. S, GRAY, O. M, MCCONVILLE, J, MCDONNELL, G. V

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Tried and tested: the psychometric properties of the multiple sclerosis impact scale (MSIS-29) in a population-based study by Gray, OM, McDonnell, GV, Hawkins, SA

“…Objective To investigate the psychometric properties of the Multiple Sclerosis Impact Scale (MSIS-29) and to assess the relationship between the Kurtzke…”
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A systematic review of oral methotrexate for multiple sclerosis by Gray, O M, McDonnell, G V, Forbes, R B

“…Oral methotrexate is a potent immunosuppressant, which could have a beneficial effect on relapse rates and delay disease progression in multiple sclerosis…”
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An investigation of susceptibility loci in benign, aggressive and primary progressive multiple sclerosis in Northern Irish population by Gray, OM, Abdeen, H, McDonnell, GV, Patterson, CC, Graham, CA, Hawkins, SA

“…Objective To investigate the possibility that susceptibility loci in multiple sclerosis (MS) have a role in determining the disease outcome in Northern Ireland…”
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An Improved Permeabilization Protocol for the Introduction of Peptides Into Cardiac Myocytes: Application to Protein Kinase C Research by Johnson, John A, Gray, Mary O, Karliner, Joel S, Chen, Che-Hong, Mochly-Rosen, Daria

“…We have developed an improved, less disruptive procedure for the transient permeabilization of neonatal cardiac myocytes using saponin. The method allows…”
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A Selective ε-Protein Kinase C Antagonist Inhibits Protection of Cardiac Myocytes from Hypoxia-induced Cell Death by Gray, Mary O., Karliner, Joel S., Mochly-Rosen, Daria

“…Protein kinase C activation is thought to protect cardiac tissue from subsequent ischemic injury by a process termed preconditioning. The protein kinase C…”
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Primary isolated brainstem injury producing internuclear ophthalmoplegia by Gray, O. M., Forbes, R. B., Morrow, J. I.

“…Brainstem injuries are classically associated with a grave prognosis. We present a case of a male with primary isolated brainstem injury who had a right…”
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Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-β and endothelin-1 from fibroblasts by GRAY, M. O, LONG, C. S, KALINYAK, J. E, LI, H.-T, KARLINER, J. S

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Sustained in vivo Cardiac Protection by a Rationally Designed Peptide That Causes ε Protein Kinase C Translocation by Dorn, Gerald W., Souroujon, Miriam C., Liron, Tamar, Chen, Che-Hong, Gray, Mary O., Zhou, Hui Zhong, Csukai, Michael, Wu, Guangyu, Lorenz, John N., Mochly-Rosen, Daria

“…Brief periods of cardiac ischemia trigger protection from subsequent prolonged ischemia (preconditioning). ε Protein kinase C (ε PKC) has been suggested to…”
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Paraneoplastic sensorimotor neuropathy associated with regression of small cell lung carcinoma by Mawhinney, E, Gray, O M, McVerry, F, McDonnell, G V

“…An elderly female smoker presented with nausea and anorexia. Imaging and histopathology were consistent with a diagnosis of small cell lung cancer (SCLC). She…”
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The Lysophospholipids Sphingosine-1-Phosphate and Lysophosphatidic Acid Enhance Survival during Hypoxia in Neonatal Rat Cardiac Myocytes by Karliner, Joel S., Honbo, Norman, Summers, Kori, Gray, Mary O., Goetzl, Edward J.

“…The lysophospholipids sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) stimulate cellular proliferation and affect numerous cellular functions by…”
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A Protein Kinase C Translocation Inhibitor as an Isozyme-selective Antagonist of Cardiac Function by Johnson, J A, Gray, M O, Chen, C H, Mochly-Rosen, D

“…Protein kinase C (PKC) isozymes translocate to unique subcellular sites following activation. We previously suggested that translocation of activated isozymes…”
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Cardioprotection from Ischemia by a Brief Exposure to Physiological Levels of Ethanol: Role of Epsilon Protein Kinase C by Chen, Che-Hong, Gray, Mary O., Mochly-Rosen, Daria

“…Recent epidemiological studies indicate beneficial effects of moderate ethanol consumption in ischemic heart disease. Most studies, however, focus on the…”
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Translocation Inhibitors Define Specificity of Protein Kinase C Isoenzymes in Pancreatic β-Cells by Yedovitzky, Michael, Mochly-Rosen, Daria, Johnson, John A., Gray, Mary O., Ron, Dorit, Abramovitch, Eva, Cerasi, Erol, Nesher, Rafael

“…The protein kinase C (PKC) family consists of 11 isoenzymes. Following activation, each isoenzyme translocates and binds to a specific receptor for activated…”
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Neonatal Mouse Cardiac Myocytes Exhibit Cardioprotection Induced by Hypoxic and Pharmacologic Preconditioning and by Transgenic Overexpression of Human Cu/Zn Superoxide Dismutase by Karliner, Joel S., Honbo, Norman, Epstein, Charles J., Xian, Meiwei, Lau, Yun-Fai Chris, Gray, Mary O.

“…Although mouse models have been increasingly used for studies of cardiac pathophysiology, there is little information regarding cultured murine cardiac…”
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Novel methods for the synthesis of functionalized indoles from arylhydroxylamines and activated acetylenes by Hwu, Jih Ru, Patel, Himatkumar V, Lin, Ren Jye, Gray, Marissa O

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Chronic ethanol-induced myocardial protection requires activation of mitochondrial K(ATP) channels by Zhu, P, Zhou, H Z, Gray, M O

“…Moderate alcohol consumption protects against coronary heart disease by unclear mechanisms. We tested whether chronic ethanol preconditioning requires…”
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Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon by Gray, Mary O, Zhou, Hui-Zhong, Schafhalter-Zoppoth, Ingeborg, Zhu, Peili, Mochly-Rosen, Daria, Messing, Robert O

“…Signaling pathways involving protein kinase C isozymes are modulators of cardiovascular development and response to injury. Protein kinase C epsilon activation…”
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