Search Results - "GRAY, Michael J"

Oxidative stress protection by polyphosphate — new roles for an old player by Gray, Michael J, Jakob, Ursula

“…Highlights • Polyphosphate protects bacteria from oxidative stress by multiple mechanisms. • Polyphosphate is a chaperone that prevents aggregation of oxidized…”
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Bacterial Responses to Reactive Chlorine Species by Gray, Michael J, Wholey, Wei-Yun, Jakob, Ursula

“…Hypochlorous acid (HOCl), the active ingredient of household bleach, is the most common disinfectant in medical, industrial, and domestic use and plays an…”
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Polyphosphate Is a Primordial Chaperone by Gray, Michael J., Wholey, Wei-Yun, Wagner, Nico O., Cremers, Claudia M., Mueller-Schickert, Antje, Hock, Nathaniel T., Krieger, Adam G., Smith, Erica M., Bender, Robert A., Bardwell, James C.A., Jakob, Ursula

“…Composed of up to 1,000 phospho-anhydride bond-linked phosphate monomers, inorganic polyphosphate (polyP) is one of the most ancient, conserved, and enigmatic…”
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Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype, and Increased Sensitivity to Insulin-like Growth Factor-I Receptor Inhibition by DALLAS, Nikolaos A, LING XIA, FAN FAN, GRAY, Michael J, GAUR, Puja, VAN BUREN, George, SAMUEL, Shaija, KIM, Michael P, LIM, Sherry J, ELLIS, Lee M

“…5-Fluorouracil (5FU) and oxaliplatin are standard therapy for metastatic colorectal cancer (CRC), but the development of chemoresistance is inevitable. Because…”
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Endoglin (CD105): A Marker of Tumor Vasculature and Potential Target for Therapy by DALLAS, Nikolaos A, SAMUEL, Shaija, LING XIA, FAN FAN, GRAY, Michael J, LIM, Sherry J, ELLIS, Lee M

“…Endoglin (CD105) is an accessory protein of the transforming growth factor-β receptor system expressed on vascular endothelial cells. Mutation of the endoglin…”
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Chronic Oxaliplatin Resistance Induces Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cell Lines by YANG, Anthony D, FAN FAN, RAMSAY CAMP, E, VAN BUREN, George, WENBIAO LIU, SOMCIO, Ray, GRAY, Michael J, HAIYUN CHENG, HOFF, Paulo M, ELLIS, Lee M

“…Purpose: Epithelial-to-mesenchymal transition (EMT) is a process whereby cells acquire molecular alterations that facilitate cell motility and invasion. In…”
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Role of Class 3 Semaphorins and Their Receptors in Tumor Growth and Angiogenesis by Gaur, Puja, Bielenberg, Diane R, Samuel, Shaija, Bose, Debashish, Zhou, Yunfei, Gray, Michael J, Dallas, Nikolaos A, Fan, Fan, Xia, Ling, Lu, Jia, Ellis, Lee M

“…Class 3 semaphorins (SEMA3) were first identified as glycoproteins that negatively mediate neuronal guidance by binding to neuropilin and repelling neurons…”
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Inorganic Polyphosphate Accumulation in Escherichia coli Is Regulated by DksA but Not by (p)ppGpp by Gray, Michael J

“…Production of inorganic polyphosphate (polyP) by bacteria is triggered by a variety of different stress conditions. polyP is required for stress survival and…”
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The role of metals in hypothiocyanite resistance in Escherichia coli by Gray, Michael J

“…The innate immune system employs a variety of antimicrobial oxidants to control and kill host-associated bacteria. Hypothiocyanite/hypothiocyanous acid (…”
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Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells by YANG, Anthony D, RAMSAY CAMP, E, ELLIS, Lee M, FAN FAN, LANLAN SHEN, GRAY, Michael J, WENBIAO LIU, SOMCIO, Ray, BAUER, Todd W, YAN WU, HICKLIN, Daniel J

“…Our laboratory has shown that vascular endothelial growth factor receptor-1 (VEGFR-1) expression on human pancreatic cancer cell lines mediates cell migration…”
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Interactions between DksA and Stress-Responsive Alternative Sigma Factors Control Inorganic Polyphosphate Accumulation in Escherichia coli by Gray, Michael J

“…Bacteria synthesize inorganic polyphosphate (polyP) in response to a variety of different stress conditions. polyP protects bacteria by acting as a…”
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A Full-Genome Phylogenetic Analysis of Varicella-Zoster Virus Reveals a Novel Origin of Replication-Based Genotyping Scheme and Evidence of Recombination between Major Circulating Clades by PETERS, Geoffrey A, TYLER, Shaun D, GROSE, Charles, SEVERINI, Alberto, GRAY, Michael J, UPTON, Chris, TIPPLES, Graham A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Vascular endothelial growth factor receptor‐1 promotes migration and invasion in pancreatic carcinoma cell lines by Wey, Jane S., Fan, Fan, Gray, Michael J., Bauer, Todd W., McCarty, Marya F., Somcio, Ray, Liu, Wenbiao, Evans, Douglas B., Wu, Yan, Hicklin, Daniel J., Ellis, Lee M.

“…BACKGROUND Vascular endothelial growth factor receptor‐1 (VEGFR‐1) is one of three receptor tyrosine kinases for VEGF, a key regulator of angiogenesis in…”
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Listeria monocytogenes Isolates from Foods and Humans Form Distinct but Overlapping Populations by GRAY, Michael J, ZADOKS, Ruth N, FORTES, Esther D, DOGAN, Belgin, CAI, Steven, YUHUAN CHEN, SCOTT, Virginia N, GOMBAS, David E, BOOR, Kathryn J, WIEDMANN, Martin

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Neuropilin-2–Mediated Tumor Growth and Angiogenesis in Pancreatic Adenocarcinoma by Dallas, Nikolaos A, Gray, Michael J, Xia, Ling, Fan, Fan, van Buren, 2nd, George, Gaur, Puja, Samuel, Shaija, Lim, Sherry J, Arumugam, Thiruvengadam, Ramachandran, Vijaya, Wang, Huamin, Ellis, Lee M

“…Purpose. Neuropilin-2 (NRP-2) is a coreceptor for vascular endothelial growth factor (VEGF) on endothelial cells. NRP-2 is overexpressed in pancreatic ductal…”
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Inorganic polyphosphate in host and microbe biology by Bowlin, Marvin Q., Gray, Michael J.

“…Inorganic polyphosphate (polyP) is produced by both bacteria and their eukaryotic hosts, and it appears to play multiple important roles in the interactions…”
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Protein Quality Control under Oxidative Stress Conditions by Dahl, Jan-Ulrik, Gray, Michael J., Jakob, Ursula

“…Accumulation of reactive oxygen and chlorine species (RO/CS) is generally regarded to be a toxic and highly undesirable event, which serves as contributing…”
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Complex Responses to Hydrogen Peroxide and Hypochlorous Acid by the Probiotic Bacterium Lactobacillus reuteri by Basu Thakur, Poulami, Long, Abagail R, Nelson, Benjamin J, Kumar, Ranjit, Rosenberg, Alexander F, Gray, Michael J

“…Inflammatory diseases of the gut are associated with increased intestinal oxygen concentrations and high levels of inflammatory oxidants, including hydrogen…”
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Saccade adaptation deficits in developmental dyslexia suggest disruption of cerebellar-dependent learning by Freedman, Edward G, Molholm, Sophie, Gray, Michael J, Belyusar, Daniel, Foxe, John J

“…Estimates of the prevalence of developmental dyslexia in the general population range from 5% to as many as 10%. Symptoms include reading, writing, and…”
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About the dangers, costs and benefits of living an aerobic lifestyle by Knoefler, Daniela, Leichert, Lars I O, Thamsen, Maike, Cremers, Claudia M, Reichmann, Dana, Gray, Michael J, Wholey, Wei-Yun, Jakob, Ursula

“…The era in which ROS (reactive oxygen species) were simply the 'bad boys of biology' is clearly over. High levels of ROS are still rightfully considered to be…”
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