Search Results - "GRAY, FRANCOISE"

Translational evidence for two distinct patterns of neuroaxonal injury in sepsis: a longitudinal, prospective translational study by Ehler, Johannes, Barrett, Lucinda K, Taylor, Valerie, Groves, Michael, Scaravilli, Francesco, Wittstock, Matthias, Kolbaske, Stephan, Grossmann, Annette, Henschel, Jörg, Gloger, Martin, Sharshar, Tarek, Chretien, Fabrice, Gray, Francoise, Nöldge-Schomburg, Gabriele, Singer, Mervyn, Sauer, Martin, Petzold, Axel

“…Brain homeostasis deteriorates in sepsis, giving rise to a mostly reversible sepsis-associated encephalopathy (SAE). Some survivors experience chronic…”
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Intracortical infarcts in small vessel disease: a combined 7-T postmortem MRI and neuropathological case study in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy by Jouvent, Eric, Poupon, Cyril, Gray, Françoise, Paquet, Claire, Mangin, Jean-François, Le Bihan, Denis, Chabriat, Hugues

“…The purpose of this study was to report the detection of infarcts of the cerebral cortex in a patient with cerebral autosomal-dominant arteriopathy with…”
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Brain lesions in septic shock : a magnetic resonance imaging study by SHARSHAR, Tarek, CARLIER, Robert, ANNANE, Djillali, BERNARD, Francis, GUIDOUX, Céline, BROULAND, Jean-Philippe, NARDI, Olivier, LORIN DE LA GRANDMAISON, Geoffroy, ABOAB, Jérome, GRAY, Francoise, MENON, David

“…Understanding of sepsis-induced brain dysfunction remains poor, and relies mainly on data from animals or post-mortem studies in patients. The current study…”
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Cortical neuronal apoptosis in CADASIL by VISWANATHAN, Anand, GRAY, Francoise, BOUSSER, Marie-Germaine, BAUDRIMONT, Marielle, CHABRIAT, Hugues

“…Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations of the NOTCH3 gene and is a model…”
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The Changing Pattern of HIV Neuropathology in the HAART Era by GRAY, FRANÇOISE, CHRÉTIEN, FABRICE, VALLAT-DECOUVELAERE, ANNE VALÉRIE, SCARAVILLI, FRANCESCO

“…Highly active antiretroviral treatment (HAART), which has been available for most AIDS patients in France since 1996, has resulted in a dramatic improvement of…”
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Pathogenesis of Cerebral Cryptococcus neoformans Infection after Fungemia by Chrétien, Fabrice, Lortholary, Olivier, Kansau, Imad, Neuville, Ségolène, Gray, Françoise, Dromer, Françoise

“…The pathogenesis of cerebral infection after Cryptococcus neoformans fungemia in outbred mice was investigated. Confocal microscopy and cultures on…”
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Brain Damage After Heat Stroke by Bazille, Céline, Megarbane, Bruno, Bensimhon, Dan, Lavergne-Slove, Anne, Baglin, Anne Catherine, Loirat, Philippe, Woimant, France, Mikol, Jacqueline, Gray, Françoise

“…Cerebellar syndromes and radiologic cerebellar atrophy after hyperpyrexia have occasionally been reported, mostly in neuroleptic malignant syndromes, but…”
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Increased Peroxynitrite Activity in AIDS Dementia Complex: Implications for the Neuropathogenesis of HIV-1 Infection by Boven, Leonie A, Gomes, Lucio, Hery, Christiane, Gray, Francoise, Verhoef, Jan, Portegies, Peter, Tardieu, Marc, Nottet, Hans S. L. M

“…Oxidative stress is suggested to be involved in several neurodegenerative diseases. One mechanism of oxidative damage is mediated by peroxynitrite, a…”
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Multifocal necrotizing leukoencephalopathy in septic shock by Sharshar, Tarek, Gray, Françoise, Poron, Frédéric, Raphael, Jean Claude, Gajdos, Philippe, Annane, Djillali

“…OBJECTIVEMultifocal necrotizing leukoencephalopathy, characterized by multiple microscopic foci of necrosis involving the white matter of the pons, has been…”
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Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway by Mouton-Liger, François, Paquet, Claire, Dumurgier, Julien, Bouras, Constantin, Pradier, Laurent, Gray, Françoise, Hugon, Jacques

“…Beta-site APP cleaving enzyme 1 (BACE1) is the rate limiting enzyme for accumulation of amyloid β (Aβ)-peptide in the brain in Alzheimer's disease (AD)…”
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CD8 Encephalitis in HIV-Infected Patients Receiving cART: A Treatable Entity by Lescure, François-Xavier, Moulignier, Antoine, Savatovsky, Julien, Amiel, Corinne, Carcelain, Guislaine, Molina, Jean-Michel, Gallien, Sébastien, Pacanovski, Jérôme, Pialoux, Gilles, Adle-Biassette, Homa, Gray, Françoise

“…Background. Despite its overall efficacy, combined antiretroviral therapy (cART) has failed to control human immunodeficiency virus (HIV) infection of the…”
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Histopathological and cognitive defects induced by Nef in the brain by Mordelet, Elodie, Kissa, Karima, Cressant, Arnaud, Gray, Francoise, Ozden, Simona, Vidal, Catherine, Charneau, Pierre, Granon, Sylvie

“…Complex mechanisms of human immunodeficiency virus type‐1 (HIV‐1) brain pathogenesis suggest the contribution of individual HIV‐1 gene products. Among them,…”
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Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline by Gourmaud, Sarah, MS, Paquet, Claire, MD, PhD, Dumurgier, Julien, MD, PhD, Pace, Clarisse, MS, Mouton-Liger, François, PhD, Hugon, Jacques, MD, PhD, Gray, Françoise, MD, PhD, Laplanche, Jean-Louis, PharmD, PhD, Bouras, Constantin, MD, PhD, Meurs, Eliane F., PhD

“…Background Alzheimer disease is characterized by cognitive decline, senile plaques of β-amyloid (Aβ) peptides, neurofibrillary tangles composed of…”
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Primary Angiitis of the Central Nervous System: Description of the First Fifty‐Two Adults Enrolled in the French Cohort of Patients With Primary Vasculitis of the Central Nervous System by Boysson, Hubert, Zuber, Mathieu, Naggara, Olivier, Neau, Jean‐Philippe, Gray, Françoise, Bousser, Marie‐Germaine, Crassard, Isabelle, Touzé, Emmanuel, Couraud, Pierre‐Olivier, Kerschen, Philippe, Oppenheim, Catherine, Detante, Olivier, Faivre, Anthony, Gaillard, Nicolas, Arquizan, Caroline, Bienvenu, Boris, Néel, Antoine, Guillevin, Loïc, Pagnoux, Christian

“…Objective To describe characteristics and outcomes of a multicenter cohort of patients diagnosed as having primary angiitis of the central nervous system…”
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Expression of Excitatory Amino Acid Transporter-1 in Brain Macrophages and Microglia of HIV-Infected Patients. A Neuroprotective Role for Activated Microglia? by VALLAT-DECOUVELAERE, ANNE VALÉRIE, CHRÉTIEN, FABRICE, GRAS, GABRIEL, LE PAVEC, GWENAELLE, DORMONT, DOMINIQUE, GRAY, FRANÇOISE

“…Recent experimental studies showed that activated macrophages/microglia (AMM) express excitatory amino acid transporters (EAATs), suggesting that, in addition…”
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Encephalitis with Infiltration by CD8+ Lymphocytes in HIV Patients Receiving Combination Antiretroviral Treatment by Gray, Françoise, Lescure, François Xavier, Adle-Biassette, Homa, Polivka, Marc, Gallien, Sébastien, Pialoux, Gilles, Moulignier, Antoine

“…We report the neuropathological findings in 10 HIV‐infected patients treated by combination antiretroviral therapy who developed subacute encephalopathy of…”
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The Neuropathology of Septic Shock by Sharshar, Tarek, Annane, Djillali, de la Gradmaison, Geoffroy Lorin, Brouland, Jean Philippe, Hopkinson, Nicholas S, Gray, Françoise

“…The neuropathological correlates of encephalopathy and autonomic dysfuction in septic shock are unclear. We performed post mortem analysis of 5 brain areas…”
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Increased Cerebrospinal Fluid Levels of Double-Stranded RNA-Dependant Protein Kinase in Alzheimer's Disease by Mouton-Liger, François, Paquet, Claire, Dumurgier, Julien, Lapalus, Pauline, Gray, Françoise, Laplanche, Jean-Louis, Hugon, Jacques

“…Background The pathological hallmarks of Alzheimer's disease (AD) include accumulation of amyloid-β (Aß) peptide forming extracellular senile plaques,…”
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Aβ-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy by Scolding, Neil J., Joseph, Fady, Kirby, Patricia A., Mazanti, Ingrid, Gray, Françoise, Mikol, Jacqueline, Ellison, David, Hilton, David A., Williams, Timothy L., MacKenzie, James M., Xuereb, John H., Love, Seth

“…Idiopathic or primary angiitis of the CNS (PACNS) and cerebral amyloid angiopathy (CAA) are unusual vasculopathies generally regarded as unrelated disorders. A…”
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Modulation of Tau Phosphorylation by the Kinase PKR: Implications in Alzheimer's Disease by Bose, Anindita, Mouton-Liger, François, Paquet, Claire, Mazot, Pierre, Vigny, Marc, Gray, Françoise, Hugon, Jacques

“…Double‐stranded RNA dependent kinase (PKR) is a pro‐apoptotic kinase that controls protein translation. Previous studies revealed that activated PKR is…”
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