Search Results - "GRAVEKAMP, C"

Myeloid-derived suppressor cells have a central role in attenuated Listeria monocytogenes-based immunotherapy against metastatic breast cancer in young and old mice by Chandra, D, Jahangir, A, Quispe-Tintaya, W, Einstein, M H, Gravekamp, C

“…Background: Myeloid-derived suppressor cells (MDSCs) are present in large numbers in blood of mice and humans with cancer, and they strongly inhibit T-cell and…”
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Myeloid-derived suppressor cells have a central role in attenuated Listeria monocytogenes-based immunotherapy against metastatic breast cancer in young and old mice by CHANDRA, D, JAHANGIR, A, QUISPE-TINTAYA, W, EINSTEIN, M. H, GRAVEKAMP, C

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Mage-b vaccine delivered by recombinant Listeria monocytogenes is highly effective against breast cancer metastases by Kim, S H, Castro, F, Gonzalez, D, Maciag, P C, Paterson, Y, Gravekamp, C

“…New therapies are needed that target breast cancer metastases. In previous studies, we have shown that vaccination with pcDNA3.1-Mage-b DNA vaccine is…”
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Direct incorporation of the NKT-cell activator α-galactosylceramide into a recombinant Listeria monocytogenes improves breast cancer vaccine efficacy by Singh, M, Quispe-Tintaya, W, Chandra, D, Jahangir, A, Venkataswamy, M M, Ng, T W, Sharma-Kharkwal, S, Carreño, L J, Porcelli, S A, Gravekamp, C

“…Background: Immune suppression in the tumour microenvironment remains a major limitation to successful immunotherapy of cancer. In the current study, we…”
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Targeted radionuclide therapies for pancreatic cancer by Shah, M, Da Silva, R, Gravekamp, C, Libutti, S K, Abraham, T, Dadachova, E

“…Pancreatic malignancies, the fourth leading cause of cancer deaths, have an aggressive behavior with poor prognosis, resulting in a 5-year survival rate of…”
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Vaccination with Mage-b DNA induces CD8 T-cell responses at young but not old age in mice with metastatic breast cancer by Castro, F, Leal, B, Denny, A, Bahar, R, Lampkin, S, Reddick, R, Lu, S, Gravekamp, C

“…Background: Elderly individuals react less efficiently to vaccines than do adults, mainly because of T-cell unresponsiveness. In this study, we analysed…”
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New approaches in cancer vaccination at old age by Gravekamp, C, Chandra, D, Quispe, W, Singh, M, Jahangir, A

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The alpha C protein mediates internalization of group B Streptococcus within human cervical epithelial cells by Bolduc, G. R., Baron, M. J., Gravekamp, C., Lachenauer, C. S., Madoff, L. C.

“…Summary Group B Streptococcus (GBS) is the leading cause of bacterial chorioamnionitis and neonatal pneumonia, sepsis, and meningitis. Deletion of the alpha C…”
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Deletion of Repeats in the Alpha C Protein Enhances the Pathogenicity of Group B Streptococci in Immune Mice by GRAVEKAMP, C, ROSNER, B, MADOFF, L. C

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Detection of leptospires in urine by PCR for early diagnosis of leptospirosis by BAL, A. E, GRAVEKAMP, C, HARTSKEERL, R. A, DE MEZA-BREWSTER, J, KORVER, H, TERPSTRA, W. J

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Evaluation of the polymerase chain reaction for early diagnosis of leptospirosis by Brown, P. D, Gravekamp, C, Carrington, D. G, van de Kemp, H, Hartskeerl, R. A, Edwards, C. N, Everard, C. O. R, Terpstra, W. J, Levett, P. N

“…University of the West Indies, Faculty of Medical Sciences, Queen Elizabeth Hospital, Bridgetown, Barbados * Department of Medicine, Queen Elizabeth Hospital,…”
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Variation in repeat number within the alpha C protein of group B streptococci alters antigenicity and protective epitopes by Gravekamp, C, Horensky, D S, Michel, J L, Madoff, L C

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Leptospirosis in Travelers by van Crevel, Reinout, Speelman, Peter, Gravekamp, Claudia, Terpstra, Wiepko J.

“…Between 1987 and 1991 leptospirosis in 32 Dutch travelers was diagnosed. Infections were acquired predominantly in Thailand and other Southeast Asian…”
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Immunogenicity and protective efficacy of the alpha C protein of group B streptococci are inversely related to the number of repeats by GRAVEKAMP, C, KASPER, D. L, MICHEL, J. L, KLING, D. E, CAREY, V, MADOFF, L. C

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Cancer vaccines in old age by Gravekamp, Claudia

“…The incidence of cancer has increased over the last decade, mainly due to an increase in the elderly population. Vaccine therapy for cancer is less toxic than…”
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Detection of leptospires in urine by polymerase chain reaction by VAN EYS, G. J. J. M, GRAVEKAMP, C, GERRITSEN, M. J, QUINT, W, CORNELISSEN, M. T. E, TER SCHEGGET, J, TERPSTRA, W. J

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Characterization of two distinct opsonic and protective epitopes within the alpha C protein of the group B Streptococcus by KLING, D. E, GRAVEKAMP, C, MADOFF, L. C, MICHEL, J. L

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Direct incorporation of the NKT-cell activator [alpha]-galactosylceramide into a recombinant Listeria monocytogenes improves breast cancer vaccine efficacy by Singh, M, Quispe-tintaya, W, Chandra, D, Jahangir, A, Venkataswamy, M M, Ng, T W, Sharma-kharkwal, S, Carreño, L J, Porcelli, S A, Gravekamp, C

“…Immune suppression in the tumour microenvironment remains a major limitation to successful immunotherapy of cancer. In the current study, we analysed whether…”
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Immunization with a single-repeat alpha C protein may prevent escape of lower repeat mutants of group B Streptococcus by Gravekamp, C, Kasper, D L, Madoff, L C

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Harnessing Listeria monocytogenes to target tumors by Gravekamp, Claudia, Paterson, Yvonne

“…Because of its cytosolic localization, Listeria monocytogenes (LM) has long been considered an attractive tool for delivering tumor-associated antigens (TAA)…”
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