Search Results - "GRANIER, Claude"
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Benchmarking the PEPOP methods for mimicking discontinuous epitopes
Published in BMC bioinformatics (30-12-2019)“…Computational methods provide approaches to identify epitopes in protein Ags to help characterizing potential biomarkers identified by high-throughput genomic…”
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Structural Basis for the IgE-Binding Cross-Reacting Epitopic Peptides of Cup s 3, a PR-5 Thaumatin-like Protein Allergen from Common Cypress (Cupressus sempervirens) Pollen
Published in Allergies (10-01-2023)“…The present work was aimed at identifying the IgE-binding epitopic regions on the surface of the Cup s 3 allergen from the common cypress Cupressus…”
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Identification of Potential IgE-Binding Epitopes Contributing to the Cross-Reactivity of the Major Cupressaceae Pectate-Lyase Pollen Allergens (Group 1)
Published in Allergies (05-09-2022)“…Pectate-lyase allergens, the group 1 of allergens from Cupressaceae pollen, consist of glycoproteins exhibiting an extremely well-conserved three-dimensional…”
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PEPOP: computational design of immunogenic peptides
Published in BMC bioinformatics (30-01-2008)“…Most methods available to predict protein epitopes are sequence based. There is a need for methods using 3D information for prediction of discontinuous…”
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Identification of new sphingomyelinases D in pathogenic fungi and other pathogenic organisms
Published in PloS one (01-11-2013)“…Sphingomyelinases D (SMases D) or dermonecrotic toxins are well characterized in Loxosceles spider venoms and have been described in some strains of pathogenic…”
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Assay for Measurement of Intact B-Type Natriuretic Peptide Prohormone in Blood
Published in Clinical chemistry (Baltimore, Md.) (01-06-2006)“…B-Type natriuretic peptide (BNP1-32) as well as the N-terminal fragment of the prohormone containing residues 1-76 (NT-proBNP1-76), both cleavage products of…”
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Use of Phage Display technology in development of canine visceral leishmaniasis vaccine using synthetic peptide trapped in sphingomyelin/cholesterol liposomes
Published in Parasites & vectors (28-02-2015)“…BACKGROUND: Leishmania parasites can cause visceral or cutaneous disease and are found in subtropical and tropical regions of the Old and New World. The…”
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Expression of Jug r 1, the 2S albumin allergen from walnut ( Juglans regia), as a correctly folded and functional recombinant protein
Published in Peptides (New York, N.Y. : 1980) (01-07-2009)“…Jug r 1, the 2S albumin allergen from walnut, was isolated from ripe nuts as a native allergen and expressed in Escherichia coli using the Gateway ® technology…”
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Use of a synthetic biosensor for neutralizing activity-biased selection of monoclonal antibodies against atroxlysin-I, an hemorrhagic metalloproteinase from Bothrops atrox snake venom
Published in PLoS neglected tropical diseases (01-04-2014)“…The snake Bothrops atrox is responsible for the majority of envenomings in the northern region of South America. Severe local effects, including hemorrhage,…”
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Simultaneous detection and epitope mapping of anti-factor VIII antibodies
Published in Thrombosis and haemostasis (01-06-2008)“…The development of antibodies (Abs) against infused factor VIII (FVIII) is currently one of the most serious complications in the treatment of patients…”
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IgE-binding epitopic peptide mapping on a three-dimensional model built for the 13S globulin allergen of buckwheat ( Fagopyrum esculentum)
Published in Peptides (New York, N.Y. : 1980) (01-06-2009)“…The three-dimensional model built for the 13S globulin allergen of buckwheat ( Fagopyrum esculentum) consists of three protomers exhibiting the cupin motif,…”
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Anti-factor VIII antibodies: a 2005 update
Published in Thrombosis and haemostasis (01-10-2005)“…The development of anti-factor VIII (FVIII) antibodies is currently one of the most serious complications in the treatment of haemophilia A patients. Numerous…”
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A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics
Published in BMC bioinformatics (28-10-2008)“…In current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately,…”
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14
Mapping the ADF/Cofilin Binding Site on Monomeric Actin by Competitive Cross-linking and Peptide Array: Evidence for a Second Binding Site on Monomeric Actin
Published in Journal of molecular biology (23-02-2007)“…The binding sites for actin depolymerising factor (ADF) and cofilin on G-actin have been mapped by competitive chemical cross-linking using deoxyribonuclease I…”
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Molecular characterization of human B domain-specific anti-factor VIII monoclonal antibodies generated in transgenic mice
Published in Thrombosis and haemostasis (01-07-2007)“…The development of antibodies directed against factor VIII (FVIII) represents a major hurdle in the treatment of hemophilia A. Most anti-FVIII antibodies are…”
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The Central Region of Human T-Cell Leukemia Virus Type 1 Tax Protein Contains Distinct Domains Involved in Subunit Dimerization
Published in Journal of Virology (01-12-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Low Molecular Weight Peptides Restore the Procoagulant Activity of Factor VIII in the Presence of the Potent Inhibitor Antibody ESH8
Published in The Journal of biological chemistry (26-07-2002)“…Following repeated administration of factor VIII (FVIII), a significant number of hemophilia A patients develop antibodies (Abs), inhibiting the procoagulant…”
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Systematic mapping of regions of human cardiac troponin I involved in binding to cardiac troponin C: N- and C-terminal low affinity contributing regions
Published in FEBS letters (18-08-2000)“…The Spot method of multiple peptide synthesis was used to map in a systematic manner regions of the human cardiac troponin I sequence (hcTnI) involved in…”
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Anti-heavy-chain monoclonal antibodies directed to the acidic regions of the factor VIII molecule inhibit the binding of factor VIII to phospholipids and von Willebrand factor
Published in Thrombosis and haemostasis (01-09-2003)“…Recent studies have shown that inhibitors develop against acidic regions of the FVIII molecule, which contain important functional sites. However, their…”
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Mapping the Paratope of Anti-CD4 Recombinant Fab 13B8.2 by Combining Parallel Peptide Synthesis and Site-directed Mutagenesis
Published in The Journal of biological chemistry (18-04-2003)“…We analyzed antigen-binding residues from the variable domains of anti-CD4 antibody 13B8.2 using the Spot method of parallel peptide synthesis. Sixteen amino…”
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