Search Results - "GRANGER, J. P"

Pathophysiology of hypertension in pre-eclampsia: a lesson in integrative physiology by Palei, A. C., Spradley, F. T., Warrington, J. P., George, E. M., Granger, J. P.

“…Despite being one of the leading causes of maternal death and a major contributor of maternal and perinatal morbidity, the mechanisms responsible for the…”
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Systemic hemodynamic and regional blood flow changes in response to chronic reductions in uterine perfusion pressure in pregnant rats by Sholook, M M, Gilbert, J S, Sedeek, M H, Huang, M, Hester, R L, Granger, J P

“…Preeclampsia (PE) is associated with increased total peripheral resistance (TPR), reduced cardiac output (CO), and diminished uterine and placental blood flow…”
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Temporal-spatial expression of ANG-(1-7) and angiotensin-converting enzyme 2 in the kidney of normal and hypertensive pregnant rats by Joyner, J, Neves, L A A, Granger, J P, Alexander, B T, Merrill, D C, Chappell, M C, Ferrario, C M, Davis, W P, Brosnihan, K B

“…We recently demonstrated that renin-angiotensin system (RAS) overactivity during late gestation in rats is associated with increased kidney and urine levels of…”
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Pathophysiology of Hypertension During Preeclampsia Linking Placental Ischemia With Endothelial Dysfunction by Granger, Joey P, Alexander, Barbara T, Llinas, Maria T, Bennett, William A, Khalil, Raouf A

“…Studies over the past decade have provided a better understanding of the potential mechanisms responsible for the pathogenesis of preeclampsia. The initiating…”
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Endothelin: Key Mediator of Hypertension in Preeclampsia by George, Eric M, Granger, Joey P

“…Preeclampsia is a pregnancy-induced hypertensive disorder characterized by proteinuria and widespread maternal endothelial dysfunction. It remains one of the…”
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Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats by RECKELHOFF, J. F, HUIMIN ZHANG, GRANGER, J. P

“…Studies were performed in intact male and female, gonadectomized male and female, and gonadectomized female rats given testosterone for 5 weeks to investigate…”
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Gender Differences in Hypertension in Spontaneously Hypertensive Rats: Role of Androgens and Androgen Receptor by Reckelhoff, Jane F, Zhang, Huimin, Srivastava, Kumud, Granger, Joey P

“…Males are at greater risk of cardiovascular and renal disease than are females. For example, male spontaneously hypertensive rats (SHR) have higher blood…”
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Role of neuronal nitric oxide synthase in mediating renal hemodynamic changes during pregnancy by Abram, S R, Alexander, B T, Bennett, W A, Granger, J P

“…Renal plasma flow (RPF) and glomerular filtration rate (GFR) are markedly increased during pregnancy. We recently reported that the renal hemodynamic changes…”
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Renal denervation attenuates the sodium retention and hypertension associated with obesity by KASSAB, S, KATO, T, WILKINS, F. C, RONG CHEN, HALL, J. E, GRANGER, J. P

“…Recent studies have indicated that obesity is associated with hypertension, sodium retention, and increased sympathetic nervous system activity. The purpose of…”
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Atrial Natriuretic Peptide Elevation in Congestive Heart Failure in the Human by Burnett, J. C., Kao, P. C., Hu, D. C., Heser, D. W., Heublein, D., Granger, J. P., Opgenorth, T. J., Reeder, G. S.

“…A sensitive radioimmunoassay for atrial natriuretic peptide was used to examine the relation between circulating atrial natriuretic peptide and cardiac filling…”
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Role of Reactive Oxygen Species in Hypertension Produced by Reduced Uterine Perfusion in Pregnant Rats by Sedeek, Mona, Gilbert, Jeffrey S., LaMarca, Babbette B., Sholook, Myssara, Chandler, Derrick L., Wang, Yuping, Granger, Joey P.

“…Background Although recent studies indicate preeclampsia (PE) is associated with increased oxidative stress, the role of reactive oxygen species in the…”
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Effects of synthetic atrial natriuretic factor on renal function and renin release by Burnett, Jr, J C, Granger, J P, Opgenorth, T J

“…Studies were performed in anesthetized dogs (n = 5) to determine the effects of synthetic atrial natriuretic factor on renal function and renin release…”
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Pressure Natriuresis: Role of Renal Interstitial Hydrostatic Pressure by Granger, Joey P

“…The kidneys play a major role in the long-term regulation of extracellular fluid volume and arterial pressure. A central component of the feedback system for…”
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Differential Expression of Renal Nitric Oxide Synthase Isoforms During Pregnancy in Rats by Alexander, Barbara T, Miller, M. Todd, Kassab, Salah, Novak, Jackie, Reckelhoff, Jane F, Kruckeberg, Walter C, Granger, Joey P

“…Alterations in nitric oxide (NO) production have been suggested to play a role in mediating changes in renal function during normal pregnancy and in…”
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Renal mechanisms of angiotensin II-induced hypertension by Granger, J P, Schnackenberg, C G

“…The kidneys play a central role in the long-term control of arterial pressure by regulating sodium balance and extracellular fluid volume. The…”
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Enhanced Vascular Reactivity During Inhibition of Nitric Oxide Synthesis in Pregnant Rats by Khalil, Raouf A, Crews, Janice K, Novak, Jacqueline, Kassab, Salah, Granger, Joey P

“…Pregnancy-induced hypertension has been suggested to be mediated by several mechanisms, including reduced nitric oxide (NO) synthesis. In this study, the…”
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Endothelin-A receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats by KASSAB, S, MILLER, M. T, NOVAK, J, RECKELHOFF, J, CLOWER, B, GRANGER, J. P

“…The aim of this study was to examine the role of endothelin-A (ET(A)) receptors in mediating the hypertension and renal injury associated with high salt intake…”
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Effect of Angiotensin II Synthesis Blockade on the Hypertensive Response to Chronic Reductions in Uterine Perfusion Pressure in Pregnant Rats by Alexander, Barbara T, Cockrell, Kathy, Cline, Farrah D, Llinas, Maria T, Sedeek, Mona, Granger, Joey P

“…The purpose of this study was to examine the role of the renin-angiotensin system in mediating the hypertension in response to chronic reductions in uterine…”
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High-Salt Diet Enhances Vascular Reactivity in Pregnant Rats With Normal and Reduced Uterine Perfusion Pressure by Barron, Laura A, Giardina, Jena B, Granger, Joey P, Khalil, Raouf A

“…High-salt (HS) diet is often associated with increased vascular resistance and arterial pressure; however, the effects of HS intake on the vascular control…”
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Angiotensin II stimulates synthesis of endothelial nitric oxide synthase by HENNINGTON, B. S, HUIMIN ZHANG, MILLER, M. T, GRANGER, J. P, RECKELHOFF, J. F

“…Previous studies have suggested that NO may play an important role in protecting the renal vessels from angiotensin II (ANGII)-mediated vasoconstriction. One…”
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