Search Results - "GRANFORS, Torvald"

Improving the Specificity of Screening for Lethal Prostate Cancer Using Prostate-specific Antigen and a Panel of Kallikrein Markers: A Nested Case–Control Study by Stattin, Pär, Vickers, Andrew J, Sjoberg, Daniel D, Johansson, Robert, Granfors, Torvald, Johansson, Mattias, Pettersson, Kim, Scardino, Peter T, Hallmans, Göran, Lilja, Hans

“…Abstract Background A disadvantage of prostate-specific antigen (PSA) for the early detection of prostate cancer (PCa) is that many men must be screened,…”
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TMPRSS2-ERG expression predicts prostate cancer survival and associates with stromal biomarkers by Hägglöf, Christina, Hammarsten, Peter, Strömvall, Kerstin, Egevad, Lars, Josefsson, Andreas, Stattin, Pär, Granfors, Torvald, Bergh, Anders

“…The TMPRSS2-ERG gene fusion is found in approximately half of all prostate cancers. The functional and prognostic significance of TMPRSS2-ERG is, however, not…”
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Castration radiosensitizes prostate cancer tissue by impairing DNA double-strand break repair by Tarish, Firas L, Schultz, Niklas, Tanoglidi, Anna, Hamberg, Hans, Letocha, Henry, Karaszi, Katalin, Hamdy, Freddie C, Granfors, Torvald, Helleday, Thomas

“…Chemical castration improves responses to radiotherapy in prostate cancer, but the mechanism is unknown. We hypothesized that this radiosensitization is caused…”
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Immunoreactivity for prostate specific antigen and Ki67 differentiates subgroups of prostate cancer related to outcome by Hammarsten, Peter, Josefsson, Andreas, Thysell, Elin, Lundholm, Marie, Hägglöf, Christina, Iglesias-Gato, Diego, Flores-Morales, Amilcar, Stattin, Pär, Egevad, Lars, Granfors, Torvald, Wikström, Pernilla, Bergh, Anders

“…Based on gene-expression profiles, prostate tumors can be subdivided into subtypes with different aggressiveness and response to treatment. We investigated if…”
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Castration therapy results in decreased Ku70 levels in prostate cancer by Al-Ubaidi, Firas L T, Schultz, Niklas, Loseva, Olga, Egevad, Lars, Granfors, Torvald, Helleday, Thomas

“…Neoadjuvant castration improves response to radiotherapy of prostate cancer. Here, we determine whether castration therapy impairs nonhomologous end-joining…”
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High Caveolin-1 Expression in Tumor Stroma Is Associated with a Favourable Outcome in Prostate Cancer Patients Managed by Watchful Waiting by Hammarsten, Peter, Dahl Scherdin, Tove, Hägglöf, Christina, Andersson, Pernilla, Wikström, Pernilla, Stattin, Pär, Egevad, Lars, Granfors, Torvald, Bergh, Anders

“…In the present study we have investigated whether Caveolin-1 expression in non-malignant and malignant prostate tissue is a potential prognostic marker for…”
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Fatty acid amide hydrolase in prostate cancer: association with disease severity and outcome, CB1 receptor expression and regulation by IL-4 by Thors, Lina, Bergh, Anders, Persson, Emma, Hammarsten, Peter, Stattin, Pär, Egevad, Lars, Granfors, Torvald, Fowler, Christopher J

“…Recent data have indicated that there may be a dysregulation of endocannabinoid metabolism in cancer. Here we have investigated the expression of the…”
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High Lysyl Oxidase (LOX) in the Non-Malignant Prostate Epithelium Predicts a Poor Outcome in Prostate Cancer Patient Managed by Watchful Waiting by Nilsson, Maria, Hägglöf, Christina, Hammarsten, Peter, Thysell, Elin, Stattin, Pär, Egevad, Lars, Granfors, Torvald, Jernberg, Emma, Wikstrom, Pernilla, Halin Bergström, Sofia, Bergh, Anders

“…Lysyl oxidase (LOX) has been shown to both promote and suppress tumor progression, but its role in prostate cancer is largely unknown. LOX immunoreactivity was…”
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Phospho-Akt immunoreactivity in prostate cancer: relationship to disease severity and outcome, Ki67 and phosphorylated EGFR expression by Hammarsten, Peter, Cipriano, Mariateresa, Josefsson, Andreas, Stattin, Pär, Egevad, Lars, Granfors, Torvald, Fowler, Christopher J

“…In the present study, we have investigated the prognostic usefulness of phosphorylated Akt immunoreactivity (pAkt-IR) in prostate cancer using a…”
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Low Levels of Phosphorylated Epidermal Growth Factor Receptor in Nonmalignant and Malignant Prostate Tissue Predict Favorable Outcome in Prostate Cancer Patients by HAMMARSTEN, Peter, KARALIJA, Amar, JOSEFSSON, Andreas, RUDOLFSSON, Stina Häggström, WIKSTRÖM, Pernilla, EGEVAD, Lars, GRANFORS, Torvald, STATTIN, Pär, BERGH, Anders

“…Purpose: To explore if the expression of phosphorylated epidermal growth factor receptor (pEGFR) in nonmalignant and malignant prostate tissue is a potential…”
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Nuclear Stat5a/b predicts early recurrence and prostate cancer–specific death in patients treated by radical prostatectomy by Mirtti, Tuomas, MD, PhD, Leiby, Benjamin E., PhD, Abdulghani, Junaid, MD, PhD, Aaltonen, Elina, MD, Pavela, Miia, MD, Mamtani, Anita, MD, Alanen, Kalle, MD, PhD, Egevad, Lars, MD, PhD, Granfors, Torvald, MD, PhD, Josefsson, Andreas, MD, PhD, Stattin, Par, MD, PhD, Bergh, Anders, MD, PhD, Nevalainen, Marja T., MD, PhD

“…Summary There is an urgent need for reliable markers to identify patients whose prostate cancer (PCa) will recur after initial therapy and progress to lethal…”
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Castration Therapy of Prostate Cancer Results in Downregulation of HIF-1α Levels by Al-Ubaidi, Firas L.T., M.B., Ch.B, Schultz, Niklas, Ph.D, Egevad, Lars, M.D., Ph.D, Granfors, Torvald, M.D., Ph.D, Helleday, Thomas, Ph.D

“…Background and Purpose Neoadjuvant androgen deprivation in combination with radiotherapy of prostate cancer is used to improve radioresponsiveness and local…”
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ErbB2 receptor immunoreactivity in prostate cancer: relationship to the androgen receptor, disease severity at diagnosis and disease outcome by Hammarsten, Peter, Winther, Johanna, Rudolfsson, Stina H, Häggström, Jenny, Karalija, Amar, Egevad, Lars, Granfors, Torvald, Fowler, Christopher J

“…ErbB2 is a member of the epidermal growth factor family of tyrosine kinases that is centrally involved in the pathogenesis of prostate cancer and several…”
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Editor's Note: Castration Therapy Results in Decreased Ku70 Levels in Prostate Cancer by Al-Ubaidi, Firas L.T., Schultz, Niklas, Loseva, Olga, Egevad, Lars, Granfors, Torvald, Helleday, Thomas

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A single instillation of epirubicin after transurethral resection of bladder tumors prevents only small recurrences by Berrum-Svennung, Ingela, Granfors, Torvald, Jahnson, Staffan, Boman, Hans, Holmäng, Sten

“…We studied whether a single instillation of epirubicin after transurethral bladder tumor resection would influence the interval to and size of the first…”
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Combined castration and fractionated radiotherapy in an experimental prostatic adenocarcinoma by Granfors, T, Damber, J E, Bergh, A, Landström, M, Löfroth, P O, Widmark, A

“…The present study using the Dunning R3327-PAP rat prostatic adenocarcinoma model was designed to study the effect on tumor growth of castration prior to or…”
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Prostate Cancer Increases Hyaluronan in Surrounding Nonmalignant Stroma, and This Response Is Associated with Tumor Growth and an Unfavorable Outcome by Josefsson, Andreas, Adamo, Hani, Hammarsten, Peter, Granfors, Torvald, Stattin, Pär, Egevad, Lars, Laurent, Anna Engström, Wikström, Pernilla, Bergh, Anders

“…Our objective was to investigate whether the presence of a tumor increases hyaluronan (HA) levels in surrounding prostate tissues and whether this extratumoral…”
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A high cannabinoid CB1 receptor immunoreactivity is associated with disease severity and outcome in prostate cancer by Chung, Sui Chu, Hammarsten, Peter, Josefsson, Andreas, Stattin, Pär, Granfors, Torvald, Egevad, Lars, Mancini, Giacomo, Lutz, Beat, Bergh, Anders, Fowler, Christopher J

“…Abstract In the light of findings indicating that cannabinoids can affect the proliferation of a number of cancer cell types and that cannabinoid receptor…”
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Long-term followup of a randomized study of locally advanced prostate cancer treated with combined orchiectomy and external radiotherapy versus radiotherapy alone by Granfors, Torvald, Modig, Hans, Damber, Jan-Erik, Tomic, Radisa

“…In a randomized study we compared the combination of orchiectomy and radiotherapy to radiotherapy alone as treatment for locally advanced prostate cancer…”
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High density of S100A9 positive inflammatory cells in prostate cancer stroma is associated with poor outcome by Tidehag, Viktor, Hammarsten, Peter, Egevad, Lars, Granfors, Torvald, Stattin, Pär, Leanderson, Tomas, Wikström, Pernilla, Josefsson, Andreas, Hägglöf, Christina, Bergh, Anders

“…Abstract Purpose To elucidate if the density of inflammatory cells expressing S100A9 in malignant and surrounding non-malignant prostate tissues is a…”
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