Search Results - "GRANDJEAN, Philippe"

Developmental fluoride neurotoxicity: an updated review by Grandjean, Philippe

“…After the discovery of fluoride as a caries-preventing agent in the mid-twentieth century, fluoridation of community water has become a widespread…”
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Delayed discovery, dissemination, and decisions on intervention in environmental health: a case study on immunotoxicity of perfluorinated alkylate substances by Grandjean, Philippe

“…Identification and characterization of environmental hazards that impact human health must rely on the best possible science to inform and inspire appropriate…”
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Neurobehavioural effects of developmental toxicity by Grandjean, Philippe, Dr, Landrigan, Philip J, MD

“…Summary Neurodevelopmental disabilities, including autism, attention-deficit hyperactivity disorder, dyslexia, and other cognitive impairments, affect millions…”
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Health Status of Workers Exposed to Perfluorinated Alkylate Substances by Grandjean, Philippe

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Calculation of the disease burden associated with environmental chemical exposures: application of toxicological information in health economic estimation by Grandjean, Philippe, Bellanger, Martine

“…Calculation of costs and the Burden of Disease (BoD) is useful in developing resource allocation and prioritization strategies in public and environmental…”
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Plasma Concentrations of Perfluoroalkyl Substances and Risk of Type 2 Diabetes: A Prospective Investigation among U.S. Women by Sun, Qi, Zong, Geng, Valvi, Damaskini, Nielsen, Flemming, Coull, Brent, Grandjean, Philippe

“…Emerging evidence suggests that perfluoroalkyl substances (PFASs) are endocrine disruptors and may contribute to the etiology of type 2 diabetes (T2D), but…”
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Adverse Effects of Methylmercury: Environmental Health Research Implications by Grandjean, Philippe, Satoh, Hiroshi, Murata, Katsuyuki, Eto, Komyo

“…Background: The scientific discoveries of health risks resulting from methylmercury exposure began in 1865 describing ataxia, dysarthria, constriction of…”
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Neurobehavioral Deficits, Diseases, and Associated Costs of Exposure to Endocrine-Disrupting Chemicals in the European Union by Bellanger, Martine, Demeneix, Barbara, Grandjean, Philippe, Zoeller, R. Thomas, Trasande, Leonardo

“…Context: Epidemiological studies and animal models demonstrate that endocrine-disrupting chemicals (EDCs) contribute to cognitive deficits and…”
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Endocrine disrupting chemicals and COVID-19 relationships: A computational systems biology approach by Wu, Qier, Coumoul, Xavier, Grandjean, Philippe, Barouki, Robert, Audouze, Karine

“…[Display omitted] •Integrative systems toxicology to link EDCs to predictors of COVID-19 severity.•A tripartite network model to assess EDC-protein-disease…”
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Severity of COVID-19 at elevated exposure to perfluorinated alkylates by Grandjean, Philippe, Timmermann, Clara Amalie Gade, Kruse, Marie, Nielsen, Flemming, Vinholt, Pernille Just, Boding, Lasse, Heilmann, Carsten, Mølbak, Kåre

“…The course of coronavirus disease 2019 (COVID-19) seems to be aggravated by air pollution, and some industrial chemicals, such as the perfluorinated alkylate…”
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Human health implications of organic food and organic agriculture: a comprehensive review by Mie, Axel, Andersen, Helle Raun, Gunnarsson, Stefan, Kahl, Johannes, Kesse-Guyot, Emmanuelle, Rembiałkowska, Ewa, Quaglio, Gianluca, Grandjean, Philippe

“…This review summarises existing evidence on the impact of organic food on human health. It compares organic vs. conventional food production with respect to…”
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Estimating Burden and Disease Costs of Exposure to Endocrine-Disrupting Chemicals in the European Union by Trasande, Leonardo, Zoeller, R. Thomas, Hass, Ulla, Kortenkamp, Andreas, Grandjean, Philippe, Myers, John Peterson, DiGangi, Joseph, Bellanger, Martine, Hauser, Russ, Legler, Juliette, Skakkebaek, Niels E, Heindel, Jerrold J

“…Context: Rapidly increasing evidence has documented that endocrine-disrupting chemicals (EDCs) contribute substantially to disease and disability. Objective:…”
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Physico-chemical properties and gestational diabetes predict transplacental transfer and partitioning of perfluoroalkyl substances by Eryasa, Berrak, Grandjean, Philippe, Nielsen, Flemming, Valvi, Damaskini, Zmirou-Navier, Denis, Sunderland, Elsie, Weihe, Pal, Oulhote, Youssef

“…Per- and polyfluoroalkyl substances (PFASs) are a growing public health concern. Some longer chain PFASs bioaccumulate and many compounds persist in the…”
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Developmental Origins of Health and Disease: Integrating Environmental Influences by Heindel, Jerrold J, Balbus, John, Birnbaum, Linda, Brune-Drisse, Marie Noel, Grandjean, Philippe, Gray, Kimberly, Landrigan, Philip J, Sly, Peter D, Suk, William, Cory Slechta, Deborah, Thompson, Claudia, Hanson, Mark

“…There are now robust data supporting the Developmental Origins of Health and Disease (DOHaD) paradigm. This includes human and animal data focusing on…”
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Developmental origins of non-communicable disease: implications for research and public health by Barouki, Robert, Gluckman, Peter D, Grandjean, Philippe, Hanson, Mark, Heindel, Jerrold J

“…This White Paper highlights the developmental period as a plastic phase, which allows the organism to adapt to changes in the environment to maintain or…”
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Evidence on the Human Health Effects of Low-Level Methylmercury Exposure by Karagas, Margaret R., Choi, Anna L., Oken, Emily, Horvat, Milena, Schoeny, Rita, Kamai, Elizabeth, Cowell, Whitney, Grandjean, Philippe, Korrick, Susan

“…Background: Methylmercury (MeHg) is a known neurotoxicant. Emerging evidence indicates it may have adverse effects on the neurologic and other body systems at…”
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Application of benchmark analysis for mixed contaminant exposures: Mutual adjustment of perfluoroalkylate substances associated with immunotoxicity by Budtz-Jørgensen, Esben, Grandjean, Philippe

“…Developmental exposure to perfluorinated alkylate substances (PFASs) is associated with deficient IgG antibody responses to childhood vaccines. As this…”
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Serum Vaccine Antibody Concentrations in Children Exposed to Perfluorinated Compounds by Grandjean, Philippe, Andersen, Elisabeth Wreford, Budtz-Jørgensen, Esben, Nielsen, Flemming, Mølbak, Kåre, Weihe, Pal, Heilmann, Carsten

“…CONTEXT Perfluorinated compounds (PFCs) have emerged as important food contaminants. They cause immune suppression in a rodent model at serum concentrations…”
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Safety of Safety Evaluation of Pesticides: developmental neurotoxicity of chlorpyrifos and chlorpyrifos-methyl by Mie, Axel, Rudén, Christina, Grandjean, Philippe

“…Authorization of pesticides for market release requires toxicity testing on animals, typically performed by test laboratories on contract with the pesticide…”
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Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS) by Ehrlich, Veronika, Bil, Wieneke, Vandebriel, Rob, Granum, Berit, Luijten, Mirjam, Lindeman, Birgitte, Grandjean, Philippe, Kaiser, Andreas-Marius, Hauzenberger, Ingrid, Hartmann, Christina, Gundacker, Claudia, Uhl, Maria

“…Per- and polyfluoroalkyl substances (PFAS) are of public health concern, because of their ubiquitous and extremely persistent occurrence, and depending on…”
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