Search Results - "GRANDE, Joseph"
-
1
Congophilic Fibrillary Glomerulonephritis: A Case Series
Published in American journal of kidney diseases (01-09-2018)“…Congo Red positivity with birefringence under polarized light has traditionally permitted classification of organized glomerular deposits as from amyloid or…”
Get full text
Journal Article -
2
Renal Disorders in Pregnancy: Core Curriculum 2019
Published in American journal of kidney diseases (01-01-2019)“…As the incidence of chronic kidney disease increases and women pursue pregnancy at more advanced ages, the management of kidney disease in pregnancy has become…”
Get full text
Journal Article -
3
A practical guide to test blueprinting
Published in Medical teacher (03-08-2019)“…A test blueprint describes the key elements of a test, including the content to be covered, the amount of emphasis allocated to each content area, and other…”
Get full text
Journal Article -
4
KLF11 deficiency enhances chemokine generation and fibrosis in murine unilateral ureteral obstruction
Published in PloS one (12-04-2022)“…Progression of virtually all forms of chronic kidney disease (CKD) is associated with activation of pro-inflammatory and pro-fibrotic signaling pathways…”
Get full text
Journal Article -
5
Advances in the pathophysiology of pre-eclampsia and related podocyte injury
Published in Kidney international (01-08-2014)“…Pre-eclampsia is a pregnancy-specific hypertensive disorder that may lead to serious maternal and fetal complications. It is a multisystem disease that is…”
Get more information
Journal Article -
6
Cell Fusion Connects Oncogenesis with Tumor Evolution
Published in The American journal of pathology (01-07-2015)“…Cell fusion likely drives tumor evolution by undermining chromosomal and DNA stability and/or by generating phenotypic diversity; however, whether a cell…”
Get full text
Journal Article -
7
VEGF Inhibition, Hypertension, and Renal Toxicity
Published in Current oncology reports (01-08-2012)“…The use of anti-angiogenic agents as part of the therapeutic armamentarium for advanced stage solid tumors has become the standard of care in several…”
Get full text
Journal Article -
8
Changes in Glomerular Volume, Sclerosis, and Ischemia at 5 Years after Kidney Transplantation: Incidence and Correlation with Late Graft Failure
Published in Journal of the American Society of Nephrology (01-02-2023)“…Glomerular volume, ischemic glomeruli, and global glomerulosclerosis are not consistently assessed on kidney transplant biopsies. The authors evaluated…”
Get full text
Journal Article -
9
Correlation of Glomerular Size With Donor–Recipient Factors and With Response to Injury
Published in Transplantation (01-11-2021)“…BACKGROUND:Glomerular size in renal allografts is impacted by donor-recipient factors and response to injury. In serial biopsies of patients with…”
Get full text
Journal Article -
10
Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney
Published in Scientific reports (17-09-2018)“…Renal artery stenosis (RAS) caused by narrowing of arteries is characterized by microvascular damage. Macrophages are implicated in repair and injury, but the…”
Get full text
Journal Article -
11
In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes
Published in Journal of the American Society of Nephrology (01-03-2021)“…In patients with secondary (autoimmune) membranous nephropathy, two novel proteins, Exostosin 1 and Exostosin 2 (EXT1/EXT2), are potential disease antigens,…”
Get full text
Journal Article -
12
Relationship between ETS Transcription Factor ETV1 and TGF-β-regulated SMAD Proteins in Prostate Cancer
Published in Scientific reports (03-06-2019)“…The ETS transcription factor ETV1 is frequently overexpressed in aggressive prostate cancer, which is one underlying cause of this disease. Accordingly,…”
Get full text
Journal Article -
13
Adipose Tissue-Derived Mesenchymal Stem Cells Improve Revascularization Outcomes to Restore Renal Function in Swine Atherosclerotic Renal Artery Stenosis
Published in Stem cells (Dayton, Ohio) (01-05-2012)“…Reno‐protective strategies are needed to improve renal outcomes in patients with atherosclerotic renal artery stenosis (ARAS). Adipose tissue‐derived…”
Get full text
Journal Article -
14
Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium
Published in Proceedings of the National Academy of Sciences - PNAS (09-04-2013)“…Inactivating mutations of the SOST (sclerostin) gene are associated with overgrowth and sclerosis of the skeleton. To determine mechanisms by which increased…”
Get full text
Journal Article -
15
Involvement of RNA helicases p68 and p72 in colon cancer
Published in Cancer research (Chicago, Ill.) (15-08-2007)“…The homologous proteins p68 and p72 are members of the DEAD box family of RNA helicases. Here, we show that expression of both of these helicases strongly…”
Get full text
Journal Article -
16
Ccl2 deficiency protects against chronic renal injury in murine renovascular hypertension
Published in Scientific reports (05-06-2018)“…Inflammation plays an important role in the pathogenesis of renal and cardiovascular disease in renovascular hypertension (RVH). Ccl2 is an important mediator…”
Get full text
Journal Article -
17
Urinary Extracellular Vesicles of Podocyte Origin and Renal Injury in Preeclampsia
Published in Journal of the American Society of Nephrology (01-11-2017)“…Renal histologic expression of the podocyte-specific protein, nephrin, but not podocin, is reduced in preeclamptic compared with normotensive pregnancies. We…”
Get full text
Journal Article -
18
Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins
Published in American journal of physiology. Renal physiology (01-05-2018)“…Destabilized heme proteins release heme, and free heme is toxic. Heme is now recognized as an agonist for the Toll-like receptor-4 (TLR4) receptor. This study…”
Get more information
Journal Article -
19
Noninvasive Assessment of Renal Fibrosis with Magnetization Transfer MR Imaging: Validation and Evaluation in Murine Renal Artery Stenosis
Published in Radiology (01-04-2017)“…Purpose To test the utility of magnetization transfer imaging in detecting and monitoring the progression of renal fibrosis in mice with unilateral renal…”
Get full text
Journal Article -
20
Evidence for Antibody-Mediated Injury as a Major Determinant of Late Kidney Allograft Failure
Published in Transplantation (15-07-2010)“…Late graft failure (LGF) is believed to be the consequence of immunologic and nonimmunologic insults leading to progressive deterioration in kidney function…”
Get full text
Journal Article