Search Results - "GRAJKOWSKA, Wieslawa A"

Neuropathological characteristics of the brain in two patients with SLC19A3 mutations related to the biotin-thiamine-responsive basal ganglia disease by Pronicki, Maciej, Piekutowska-Abramczuk, Dorota, Jurkiewicz, Elżbieta, Rokicki, Dariusz, Ciara, Elżbieta, Trubicka, Joanna, Iwanicka-Pronicka, Katarzyna, Pajdowska, Magdalena, Migdał, Marek, Grajkowska, Wieslawa A

“…Biotin-thiamine-responsive basal ganglia disease is a severe form of a rare neurogenetic disorder caused by pathogenic molecular variants in the thiamine…”
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Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis by Thompson, Eric M, MD, Hielscher, Thomas, MSc, Bouffet, Eric, Prof, Remke, Marc, MD, Luu, Betty, BSc, Gururangan, Sridharan, Prof, McLendon, Roger E, Prof, Bigner, Darell D, Prof, Lipp, Eric S, MD, Perreault, Sebastien, MD, Cho, Yoon-Jae, MD, Grant, Gerald, MD, Kim, Seung-Ki, Prof, Lee, Ji Yeoun, MD, Rao, Amulya A Nageswara, MD, Li, Kay Ka Wai, MD, Ng, Ho-Keung, Prof, Yao, Yu, MD, Kumabe, Toshihiro, MD, Tominaga, Teiji, Prof, Grajkowska, Wieslawa A, Prof, Perek-Polnik, Marta, Prof, Low, David C Y, MBBCh, Seow, Wan Tew, MBBS, Chang, Kenneth T E, MBBCh, Mora, Jaume, Prof, Pollack, Ian F, Prof, Hamilton, Ronald L, MD, Leary, Sarah, MD, Moore, Andrew S, PhD, Ingram, Wendy J, PhD, Hallahan, Andrew R, MBBS, Jouvet, Anne, MD, Fèvre-Montange, Michelle, PhD, Vasiljevic, Alexandre, MD, Faure-Conter, Cecile, MD, Shofuda, Tomoko, PhD, Hashimoto, Naoya, MD, Jabado, Nada, MD, Weil, Alexander G, MD, Gayden, Tenzin, PhD, Wataya, Takafumi, MD, Shalaby, Tarek, MD, Grotzer, Michael, Prof, Zitterbart, Karel, PhD, Sterba, Jaroslav, Prof, Kren, Leos, MD, Hortobágyi, Tibor, Prof, Klekner, Almos, PhD, László, Bognár, Prof, Pócza, Tímea, MSc, Hauser, Peter, MD, Schüller, Ulrich, MD, Jung, Shin, Prof, Jang, Woo-Youl, MD, French, Pim J, Prof, Kros, Johan M, Prof, van Veelen, Marie-Lise C, MD, Massimi, Luca, MD, Leonard, Jeffrey R, Prof, Rubin, Joshua B, MD, Vibhakar, Rajeev, MD, Chambless, Lola B, MD, Cooper, Michael K, MD, Thompson, Reid C, Prof, Carvalho, Alice, MD, Nunes, Sofia, MD, Pimentel, José, MD, Fan, Xing, MD, Lyden, David, Prof, Garzia, Livia, PhD, Shih, David J H, PhD, Kijima, Noriyuki, MD, Schneider, Christian, MD, Adamski, Jennifer, PhD, Northcott, Paul A, PhD, Kool, Marcel, PhD, Jones, David T W, PhD, Chan, Jennifer A, MD, Nikolic, Ana, MD, Garre, Maria Luisa, MD, Van Meir, Erwin G, Prof, Osuka, Satoru, MD, Olson, Jeffrey J, Prof, Jahangiri, Arman, BSc, Castro, Brandyn A, BSc, Gupta, Nalin, MD, Moxon-Emre, Iska, MSc, Mabbott, Donald J, PhD, Lassaletta, Alvaro, MD, Hawkins, Cynthia E, Prof, Tabori, Uri, MD, Drake, James, Prof, Kulkarni, Abhaya, Prof, Dirks, Peter, Prof, Rutka, James T, Prof, Pfister, Stefan M, Prof, Packer, Roger J, Prof, Ramaswamy, Vijay, MD, Taylor, Michael D, Dr Prof

“…Summary Background Patients with incomplete surgical resection of medulloblastoma are controversially regarded as having a marker of high-risk disease, which…”
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Intertumoral Heterogeneity within Medulloblastoma Subgroups by Cavalli, Florence M.G., Remke, Marc, Rampasek, Ladislav, Peacock, John, Shih, David J.H., Luu, Betty, Garzia, Livia, Torchia, Jonathon, Nor, Carolina, Morrissy, A. Sorana, Agnihotri, Sameer, Thompson, Yuan Yao, Kuzan-Fischer, Claudia M., Farooq, Hamza, Isaev, Keren, Daniels, Craig, Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Lee, Ji Yeoun, Grajkowska, Wieslawa A., Perek-Polnik, Marta, Vasiljevic, Alexandre, Faure-Conter, Cecile, Jouvet, Anne, Giannini, Caterina, Nageswara Rao, Amulya A., Li, Kay Ka Wai, Ng, Ho-Keung, Eberhart, Charles G., Pollack, Ian F., Hamilton, Ronald L., Gillespie, G. Yancey, Olson, James M., Leary, Sarah, Weiss, William A., Lach, Boleslaw, Chambless, Lola B., Thompson, Reid C., Cooper, Michael K., Vibhakar, Rajeev, Hauser, Peter, van Veelen, Marie-Lise C., Kros, Johan M., French, Pim J., Ra, Young Shin, Kumabe, Toshihiro, López-Aguilar, Enrique, Zitterbart, Karel, Sterba, Jaroslav, Finocchiaro, Gaetano, Massimino, Maura, Van Meir, Erwin G., Osuka, Satoru, Shofuda, Tomoko, Klekner, Almos, Zollo, Massimo, Leonard, Jeffrey R., Rubin, Joshua B., Jabado, Nada, Albrecht, Steffen, Mora, Jaume, Van Meter, Timothy E., Jung, Shin, Moore, Andrew S., Hallahan, Andrew R., Chan, Jennifer A., Tirapelli, Daniela P.C., Carlotti, Carlos G., Fouladi, Maryam, Pimentel, José, Faria, Claudia C., Saad, Ali G., Massimi, Luca, Liau, Linda M., Wheeler, Helen, Nakamura, Hideo, Elbabaa, Samer K., Perezpeña-Diazconti, Mario, Chico Ponce de León, Fernando, Robinson, Shenandoah, Zapotocky, Michal, Lassaletta, Alvaro, Huang, Annie, Hawkins, Cynthia E., Tabori, Uri, Bouffet, Eric, Bartels, Ute, Dirks, Peter B., Rutka, James T., Bader, Gary D., Reimand, Jüri, Goldenberg, Anna, Ramaswamy, Vijay, Taylor, Michael D.

“…While molecular subgrouping has revolutionized medulloblastoma classification, the extent of heterogeneity within subgroups is unknown. Similarity network…”
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Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma by Suzuki, Hiromichi, Kumar, Sachin A., Shuai, Shimin, Diaz-Navarro, Ander, Gutierrez-Fernandez, Ana, De Antonellis, Pasqualino, Cavalli, Florence M. G., Juraschka, Kyle, Farooq, Hamza, Shibahara, Ichiyo, Vladoiu, Maria C., Zhang, Jiao, Abeysundara, Namal, Przelicki, David, Skowron, Patryk, Gauer, Nicole, Luu, Betty, Daniels, Craig, Wu, Xiaochong, Forget, Antoine, Momin, Ali, Wang, Jun, Dong, Weifan, Kim, Seung-Ki, Grajkowska, Wieslawa A., Jouvet, Anne, Fèvre-Montange, Michelle, Garrè, Maria Luisa, Nageswara Rao, Amulya A., Giannini, Caterina, Kros, Johan M, French, Pim J., Jabado, Nada, Ng, Ho-Keung, Poon, Wai Sang, Eberhart, Charles G., Pollack, Ian F., Olson, James M., Weiss, William A., Kumabe, Toshihiro, López-Aguilar, Enrique, Lach, Boleslaw, Massimino, Maura, Van Meir, Erwin G., Rubin, Joshua B., Vibhakar, Rajeev, Chambless, Lola B., Kijima, Noriyuki, Klekner, Almos, Bognár, László, Chan, Jennifer A., Faria, Claudia, Ragoussis, Jiannis, Pfister, Stefan M., Goldenberg, Anna, Wechsler-Reya, Robert J., Bailey, Swneke D., Garzia, Livia, Morrissy, A Sorana, Marra, Marco A., Huang, Xi, Malkin, David, Ayrault, Olivier, Ramaswamy, Vijay, Puente, Xose S., Calarco, John A., Stein, Lincoln, Taylor, Michael D.

“…© The Author(s), under exclusive licence to Springer Nature Limited 2019 In cancer, recurrent somatic single-nucleotide variants-which are rare in most…”
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Failure of human rhombic lip differentiation underlies medulloblastoma formation by Hendrikse, Liam D., Haldipur, Parthiv, Saulnier, Olivier, Millman, Jake, Erickson, Anders W., Gordon, Victor, Coudière-Morrison, Ludivine, Shokouhian, Mohammad, Suárez, Raúl A., Ly, Michelle, Borlase, Stephanie, Scott, David S., Farooq, Hamza, Sirbu, Olga, Nambu, Shohei, Funakoshi, Yusuke, Diaz-Mejia, J. Javier, Golser, Joseph, Bach, Kathleen, Phuong-Bao, Tram, Skowron, Patryk, Wang, Evan Y., Kumar, Sachin A., Balin, Polina, Visvanathan, Abhirami, Lee, John J. Y., Ayoub, Ramy, Mungall, Karen L., Wang, Yu C., Kim, Seung-Ki, Bourdeaut, Franck, Doz, François, Masliah-Planchon, Julien, Grajkowska, Wieslawa A., Loukides, James, Dirks, Peter, Fèvre-Montange, Michelle, French, Pim J., Kros, Johan M., Zitterbart, Karel, Bailey, Swneke D., Eberhart, Charles G., Rao, Amulya A. N., Giannini, Caterina, Olson, James M., Phillips, Joanna J., Ra, Young S., de Torres, Carmen, Mora, Jaume, Li, Kay K. W., Poon, Wai S., Pollack, Ian F., López-Aguilar, Enrique, Gillespie, G. Yancey, Shofuda, Tomoko, Vibhakar, Rajeev, Thompson, Reid C., Rubin, Joshua B., Jung, Shin, Lach, Boleslaw, Iolascon, Achille, Ferrucci, Veronica, Zollo, Massimo, Cinalli, Giuseppe, Robinson, Shenandoah, Stearns, Duncan S., Van Meir, Erwin G., Porrati, Paola, Massimino, Maura, Carlotti, Carlos G., Faria, Claudia C., Chan, Jennifer A., Aldinger, Kimberly A., Razavi, Ferechte, McLendon, Roger E., Thompson, Eric M., Ansari, Marc, Garre, Maria L., Chico, Fernando, Eguía, Pilar, Morrissy, A. Sorana, Wu, Xiaochong, Daniels, Craig, Rich, Jeremy N., Jones, Steven J. M., Marra, Marco A., Reimand, Jüri, Sorensen, Poul H., Wechsler-Reya, Robert J., Kleinman, Claudia L., Jabado, Nada, Malkin, David, Ayrault, Olivier, Golden, Jeffrey A., Ellison, David W., Doble, Brad, Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E., Suzuki, Hiromichi, Millen, Kathleen J.

“…Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain…”
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Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis by Ramaswamy, Vijay, Hielscher, Thomas, Mack, Stephen C, Lassaletta, Alvaro, Lin, Tong, Pajtler, Kristian W, Jones, David T W, Luu, Betty, Cavalli, Florence M G, Aldape, Kenneth, Remke, Marc, Mynarek, Martin, Rutkowski, Stefan, Gururangan, Sridharan, McLendon, Roger E, Lipp, Eric S, Dunham, Christopher, Hukin, Juliette, Eisenstat, David D, Fulton, Dorcas, van Landeghem, Frank K H, Santi, Mariarita, van Veelen, Marie-Lise C, Van Meir, Erwin G, Osuka, Satoru, Fan, Xing, Muraszko, Karin M, Tirapelli, Daniela P C, Oba-Shinjo, Sueli M, Marie, Suely K N, Carlotti, Carlos G, Lee, Ji Yeoun, Rao, Amulya A Nageswara, Giannini, Caterina, Faria, Claudia C, Nunes, Sofia, Mora, Jaume, Hamilton, Ronald L, Hauser, Peter, Jabado, Nada, Petrecca, Kevin, Jung, Shin, Massimi, Luca, Zollo, Massimo, Cinalli, Giuseppe, Bognár, László, Klekner, Almos, Hortobágyi, Tibor, Leary, Sarah, Ermoian, Ralph P, Olson, James M, Leonard, Jeffrey R, Gardner, Corrine, Grajkowska, Wieslawa A, Chambless, Lola B, Cain, Jason, Eberhart, Charles G, Ahsan, Sama, Massimino, Maura, Giangaspero, Felice, Buttarelli, Francesca R, Packer, Roger J, Emery, Lyndsey, Yong, William H, Soto, Horacio, Liau, Linda M, Everson, Richard, Grossbach, Andrew, Shalaby, Tarek, Grotzer, Michael, Karajannis, Matthias A, Zagzag, David, Wheeler, Helen, von Hoff, Katja, Alonso, Marta M, Tuñon, Teresa, Schüller, Ulrich, Zitterbart, Karel, Sterba, Jaroslav, Chan, Jennifer A, Guzman, Miguel, Elbabaa, Samer K, Colman, Howard, Dhall, Girish, Fisher, Paul G, Fouladi, Maryam, Gajjar, Amar, Goldman, Stewart, Hwang, Eugene, Kool, Marcel, Ladha, Harshad, Vera-Bolanos, Elizabeth, Wani, Khalida, Lieberman, Frank, Mikkelsen, Tom, Omuro, Antonio M, Pollack, Ian F, Prados, Michael, Robins, H Ian, Soffietti, Riccardo

“…Posterior fossa ependymoma comprises two distinct molecular variants termed EPN_PFA and EPN_PFB that have a distinct biology and natural history. The…”
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Subgroup-specific structural variation across 1,000 medulloblastoma genomes by Peacock, John, Zichner, Thomas, Stütz, Adrian M., Reimand, Jüri, Schumacher, Steven E., Ellison, David W., Marshall, Christian R., Lionel, Anath C., Mack, Stephen, Yao, Yuan, Ramaswamy, Vijay, Luu, Betty, Rolider, Adi, Cavalli, Florence M. G., Wang, Xin, Remke, Marc, Wu, Xiaochong, Chiu, Readman Y. B., Chuah, Eric, Corbett, Richard D., Hoad, Gemma R., Jackman, Shaun D., Lo, Allan, Mungall, Karen L., Qian, Jenny Q., Raymond, Anthony G. J., Varhol, Richard J., Birol, Inanc, Moore, Richard A., Mungall, Andrew J., Holt, Robert, Kawauchi, Daisuke, Roussel, Martine F., Jones, David T. W., Fernandez-L, Africa, Kenney, Anna M., Dirks, Peter, Aviv, Tzvi, Grajkowska, Wieslawa A., Perek-Polnik, Marta, Delattre, Olivier, Reynaud, Stéphanie S., Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Scheurlen, Wolfram, Eberhart, Charles G., Fèvre-Montange, Michelle, Jouvet, Anne, Pollack, Ian F., Fan, Xing, Muraszko, Karin M., Yancey Gillespie, G., Di Rocco, Concezio, Massimi, Luca, French, Pim J., Kros, Johan M., Ellenbogen, Richard G., Kren, Leos, Thompson, Reid C., Fontebasso, Adam, Albrecht, Steffen, Lindsey, Janet C., Bailey, Simon, Weiss, William A., Bognár, László, Klekner, Almos, Van Meter, Timothy E., Kumabe, Toshihiro, Tominaga, Teiji, Elbabaa, Samer K., Leonard, Jeffrey R., Liau, Linda M., Van Meir, Erwin G., Fouladi, Maryam, Garami, Miklós, Hauser, Peter, Saad, Ali G., Iolascon, Achille, Jung, Shin, Carlotti, Carlos G., Robinson, Shenandoah, Zollo, Massimo, Chan, Jennifer A., Levy, Michael L., Sorensen, Poul H. B., Meyerson, Matthew, Pomeroy, Scott L., Cho, Yoon-Jae, Bader, Gary D., Tabori, Uri, Hawkins, Cynthia E., Bouffet, Eric, Scherer, Stephen W., Rutka, James T., Malkin, David, Clifford, Steven C., Korbel, Jan O., Marra, Marco A., Taylor, Michael D.

“…Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain…”
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Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma by ZHUKOVA, Nataliya, RAMASWAMY, Vijay, VON BUEREN, André O, JONES, David T. W, NORTHCOTT, Paul A, KOOL, Marcel, STURM, Dominik, PUGH, Trevor J, POMEROY, Scott L, CHO, Yoon-Jae, PIETSCH, Torsten, GESSI, Marco, REMKE, Marc, RUTKOWSKI, Stefan, BOGNAR, Laszlo, KLEKNER, Almos, CHO, Byung-Kyu, KIM, Seung-Ki, WANG, Kyu-Chang, EBERHART, Charles G, FEVRE-MONTANGE, Michelle, FOULADI, Maryam, FRENCH, Pim J, PFAFF, Elke, KROS, Max, GRAJKOWSKA, Wieslawa A, GUPTA, Nalin, WEISS, William A, HAUSER, Peter, JABADO, Nada, JOUVET, Anne, SHIN JUNG, KUMABE, Toshihiro, LACH, Boleslaw, SHIH, David J. H, LEONARD, Jeffrey R, RUBIN, Joshua B, LIAU, Linda M, MASSIMI, Luca, POLLACK, Ian F, YOUNG SHIN RA, VAN MEIR, Erwin G, ZITTERBART, Karel, SCHÜLLER, Ulrich, HILL, Rebecca M, MARTIN, Dianna C, LINDSEY, Janet C, SCHWALBE, Ed C, BAILEY, Simon, ELLISON, David W, HAWKINS, Cynthia, MALKIN, David, CLIFFORD, Steven C, KORSHUNOV, Andrey, PFISTER, Stefan, TAYLOR, Michael D, CASTELO-BRANCO, Pedro, BASKIN, Berivan, RAY, Peter N, BOUFFET, Eric

“…Reports detailing the prognostic impact of TP53 mutations in medulloblastoma offer conflicting conclusions. We resolve this issue through the inclusion of…”
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Cytogenetic Prognostication Within Medulloblastoma Subgroups by SHIH, David J. H, NORTHCOTT, Paul A, GARZIA, Livia, PEACOCK, John, MACK, Stephen C, XIAOCHONG WU, ROLIDER, Adi, MORRISSY, A. Sorana, CAVALLI, Florence M. G, JONES, David T. W, ZITTERBART, Karel, FARIA, Claudia C, REMKE, Marc, SCHÜLLER, Ulrich, KREN, Leos, KUMABE, Toshihiro, TOMINAGA, Teiji, YOUNG SHIN RA, GARAMI, Miklós, HAUSER, Peter, CHAN, Jennifer A, ROBINSON, Shenandoah, BOGNAR, László, KORSHUNOV, Andrey, KLEKNER, Almos, SAAD, Ali G, LIAU, Linda M, ALBRECHT, Steffen, FONTEBASSO, Adam, CINALLI, Giuseppe, DE ANTONELLIS, Pasqualino, ZOLLO, Massimo, COOPER, Michael K, THOMPSON, Reid C, RAMASWAMY, Vijay, BAILEY, Simon, LINDSEY, Janet C, DI ROCCO, Concezio, MASSIMI, Luca, MICHIELS, Erna M. C, SCHERER, Stephen W, PHILLIPS, Joanna J, GUPTA, Nalin, XING FAN, MURASZKO, Karin M, KOOL, Marcel, VIBHAKAR, Rajeev, EBERHART, Charles G, FOULADI, Maryam, LACH, Boleslaw, SHIN JUNG, WECHSLER-REYA, Robert J, FEVRE-MONTANGE, Michelle, JOUVET, Anne, JABADO, Nada, POLLACK, Ian F, LUU, Betty, YUAN YAO, XIN WANG, DUBUC, Adrian M

“…Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3, and Group 4. Current medulloblastoma protocols stratify patients based on…”
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Subgroup and subtype-specific outcomes in adult medulloblastoma by Coltin, Hallie, Sundaresan, Lakshmikirupa, Smith, Kyle S., Skowron, Patryk, Massimi, Luca, Eberhart, Charles G., Schreck, Karisa C., Gupta, Nalin, Weiss, William A., Tirapelli, Daniela, Carlotti, Carlos, Li, Kay K. W., Ryzhova, Marina, Golanov, Andrey, Zheludkova, Olga, Absalyamova, Oksana, Okonechnikov, Konstantin, Stichel, Damian, von Deimling, Andreas, Giannini, Caterina, Raskin, Scott, Van Meir, Erwin G., Chan, Jennifer A., Fults, Daniel, Chambless, Lola B., Kim, Seung-Ki, Vasiljevic, Alexandre, Faure-Conter, Cecile, Vibhakar, Rajeev, Jung, Shin, Leary, Sarah, Mora, Jaume, McLendon, Roger E., Pollack, Ian F., Hauser, Peter, Grajkowska, Wieslawa A., Rubin, Joshua B., van Veelen, Marie-Lise C., French, Pim J., Kros, Johan M., Liau, Linda M., Pfister, Stefan M., Kool, Marcel, Kijima, Noriyuki, Taylor, Michael D., Packer, Roger J., Northcott, Paul A., Korshunov, Andrey, Ramaswamy, Vijay

“…Medulloblastoma, a common pediatric malignant central nervous system tumour, represent a small proportion of brain tumours in adults. Previously it has been…”
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The transcriptional landscape of Shh medulloblastoma by Skowron, Patryk, Farooq, Hamza, Cavalli, Florence M. G., Morrissy, A. Sorana, Ly, Michelle, Hendrikse, Liam D., Wang, Evan Y., Djambazian, Haig, Zhu, Helen, Mungall, Karen L., Trinh, Quang M., Zheng, Tina, Dai, Shizhong, Stucklin, Ana S. Guerreiro, Vladoiu, Maria C., Fong, Vernon, Holgado, Borja L., Nor, Carolina, Wu, Xiaochong, Abd-Rabbo, Diala, Bérubé, Pierre, Wang, Yu Chang, Luu, Betty, Suarez, Raul A., Rastan, Avesta, Gillmor, Aaron H., Lee, John J. Y., Zhang, Xiao Yun, Daniels, Craig, Dirks, Peter, Malkin, David, Bouffet, Eric, Tabori, Uri, Loukides, James, Doz, François P., Bourdeaut, Franck, Delattre, Olivier O., Masliah-Planchon, Julien, Ayrault, Olivier, Kim, Seung-Ki, Meyronet, David, Grajkowska, Wieslawa A., Carlotti, Carlos G., de Torres, Carmen, Mora, Jaume, Eberhart, Charles G., Van Meir, Erwin G., Kumabe, Toshihiro, French, Pim J., Kros, Johan M., Jabado, Nada, Lach, Boleslaw, Pollack, Ian F., Hamilton, Ronald L., Rao, Amulya A. Nageswara, Giannini, Caterina, Olson, James M., Bognár, László, Klekner, Almos, Zitterbart, Karel, Phillips, Joanna J., Thompson, Reid C., Cooper, Michael K., Rubin, Joshua B., Liau, Linda M., Garami, Miklós, Hauser, Peter, Li, Kay Ka Wai, Ng, Ho-Keung, Poon, Wai Sang, Yancey Gillespie, G., Chan, Jennifer A., Jung, Shin, McLendon, Roger E., Thompson, Eric M., Zagzag, David, Vibhakar, Rajeev, Ra, Young Shin, Garre, Maria Luisa, Schüller, Ulrich, Shofuda, Tomoko, Faria, Claudia, López-Aguilar, Enrique, Zadeh, Gelareh, Hui, Chi-Chung, Ramaswamy, Vijay, Bailey, Swneke D., Jones, Steven J., Mungall, Andrew J., Moore, Richard A., Calarco, John A., Stein, Lincoln D., Bader, Gary D., Reimand, Jüri, Ragoussis, Jiannis, Weiss, William A., Marra, Marco A., Suzuki, Hiromichi, Taylor, Michael D.

“…© The Author(s) 2021. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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Tu1529 – A Combined Blood and Mr Imaging Risk Score for Monitoring Liver Inflammation in Paediatric Aih by Janowski, Kamil, Dennis, Andrea, Pronicki, Maciej, Grajkowska, Wieslawa A., Wozniak, Malgorzata, Pawliszak, Piotr, Jurkiewicz, Elzbieta, Kelly, Matt, Neubauer, Stefan, Banerjee, Rajarshi, Socha, Piotr

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Mo1478 – Quantitative Mrcp Imaging: Preliminary Observations in a Cohort of Paediatric Patientswith Liver and Biliary Diseases by Janowski, Kamil, Woodward, Gary, Ridgway, Ged, Kelly, Matt, Bachtiar, Velicia, Pronicki, Maciej, Grajkowska, Wieslawa A., Wozniak, Malgorzata, Pawliszak, Piotr, Jurkiewicz, Elzbieta, Banerjee, Rajarshi, Socha, Piotr

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TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma by Remke, Marc, Ramaswamy, Vijay, Peacock, John, Shih, David J. H., Koelsche, Christian, Northcott, Paul A., Hill, Nadia, Cavalli, Florence M. G., Kool, Marcel, Wang, Xin, Mack, Stephen C., Barszczyk, Mark, Morrissy, A. Sorana, Wu, Xiaochong, Agnihotri, Sameer, Luu, Betty, Jones, David T. W., Garzia, Livia, Dubuc, Adrian M., Zhukova, Nataliya, Vanner, Robert, Kros, Johan M., French, Pim J., Van Meir, Erwin G., Vibhakar, Rajeev, Zitterbart, Karel, Chan, Jennifer A., Bognár, László, Klekner, Almos, Lach, Boleslaw, Jung, Shin, Saad, Ali G., Liau, Linda M., Albrecht, Steffen, Zollo, Massimo, Cooper, Michael K., Thompson, Reid C., Delattre, Oliver O., Bourdeaut, Franck, Doz, François F., Garami, Miklós, Hauser, Peter, Carlotti, Carlos G., Van Meter, Timothy E., Massimi, Luca, Fults, Daniel, Pomeroy, Scott L., Kumabe, Toshiro, Ra, Young Shin, Leonard, Jeffrey R., Elbabaa, Samer K., Mora, Jaume, Rubin, Joshua B., Cho, Yoon-Jae, McLendon, Roger E., Bigner, Darell D., Eberhart, Charles G., Fouladi, Maryam, Wechsler-Reya, Robert J., Faria, Claudia C., Croul, Sidney E., Huang, Annie, Bouffet, Eric, Hawkins, Cynthia E., Dirks, Peter B., Weiss, William A., Schüller, Ulrich, Pollack, Ian F., Rutkowski, Stefan, Meyronet, David, Jouvet, Anne, Fèvre-Montange, Michelle, Jabado, Nada, Perek-Polnik, Marta, Grajkowska, Wieslawa A., Kim, Seung-Ki, Rutka, James T., Malkin, David, Tabori, Uri, Pfister, Stefan M., Korshunov, Andrey, von Deimling, Andreas, Taylor, Michael D.

“…Telomerase reverse transcriptase ( TERT ) promoter mutations were recently shown to drive telomerase activity in various cancer types, including…”
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Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation by Hendrikse, Liam D., Haldipur, Parthiv, Saulnier, Olivier, Millman, Jake, Erickson, Anders W., Gordon, Victor, Coudière-Morrison, Ludivine, Shokouhian, Mohammad, Suárez, Raúl A., Ly, Michelle, Borlase, Stephanie, Scott, David S., Farooq, Hamza, Sirbu, Olga, Nambu, Shohei, Funakoshi, Yusuke, Diaz-Mejia, J. Javier, Golser, Joseph, Bach, Kathleen, Phuong-Bao, Tram, Skowron, Patryk, Wang, Evan Y., Kumar, Sachin A., Balin, Polina, Visvanathan, Abhirami, Lee, John J. Y., Ayoub, Ramy, Mungall, Karen L., Wang, Yu C., Kim, Seung-Ki, Bourdeaut, Franck, Doz, François, Masliah-Planchon, Julien, Grajkowska, Wieslawa A., Loukides, James, Dirks, Peter, Fèvre-Montange, Michelle, French, Pim J., Kros, Johan M., Zitterbart, Karel, Bailey, Swneke D., Eberhart, Charles G., Rao, Amulya A. N., Giannini, Caterina, Olson, James M., Phillips, Joanna J., Ra, Young S., de Torres, Carmen, Mora, Jaume, Li, Kay K. W., Poon, Wai S., Pollack, Ian F., López-Aguilar, Enrique, Gillespie, G. Yancey, Shofuda, Tomoko, Vibhakar, Rajeev, Thompson, Reid C., Rubin, Joshua B., Jung, Shin, Lach, Boleslaw, Iolascon, Achille, Ferrucci, Veronica, Zollo, Massimo, Cinalli, Giuseppe, Robinson, Shenandoah, Stearns, Duncan S., Van Meir, Erwin G., Porrati, Paola, Massimino, Maura, Carlotti, Carlos G., Faria, Claudia C., Chan, Jennifer A., Aldinger, Kimberly A., Razavi, Ferechte, McLendon, Roger E., Thompson, Eric M., Ansari, Marc, Garre, Maria L., Chico, Fernando, Eguía, Pilar, Morrissy, A. Sorana, Wu, Xiaochong, Daniels, Craig, Rich, Jeremy N., Jones, Steven J. M., Marra, Marco A., Reimand, Jüri, Sorensen, Poul H., Wechsler-Reya, Robert J., Kleinman, Claudia L., Jabado, Nada, Malkin, David, Ayrault, Olivier, Golden, Jeffrey A., Ellison, David W., Doble, Brad, Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E., Suzuki, Hiromichi, Millen, Kathleen J.

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Recurrent non-coding U1-snRNA mutations drive cryptic splicing in Shh medulloblastoma by Suzuki, Hiromichi, Kumar, Sachin A, Shuai, Shimin, Diaz-Navarro, Ander, Gutierrez-Fernandez, Ana, De Antonellis, Pasqualino, Cavalli, Florence M G, Juraschka, Kyle, Farooq, Hamza, Shibahara, Ichiyo, Vladoiu, Maria C, Zhang, Jiao, Abeysundara, Namal, Przelicki, David, Skowron, Patryk, Gauer, Nicole, Luu, Betty, Daniels, Craig, Wu, Xiaochong, Forget, Antoine, Momin, Ali, Wang, Jun, Dong, Weifan, Kim, Seung-Ki, Grajkowska, Wieslawa A, Jouvet, Anne, Fèvre-Montange, Michelle, Garrè, Maria Luisa, Rao, Amulya A Nageswara, Giannini, Caterina, Kros, Johan M, French, Pim J, Jabado, Nada, Ng, Ho-Keung, Poon, Wai Sang, Eberhart, Charles G, Pollack, Ian F, Olson, James M, Weiss, William A, Kumabe, Toshihiro, López-Aguilar, Enrique, Lach, Boleslaw, Massimino, Maura, Van Meir, Erwin G, Rubin, Joshua B, Vibhakar, Rajeev, Chambless, Lola B, Kijima, Noriyuki, Klekner, Almos, Bognár, László, Chan, Jennifer A, Faria, Claudia C, Ragoussis, Jiannis, Pfister, Stefan M, Goldenberg, Anna, Wechsler-Reya, Robert J, Bailey, Swneke D, Garzia, Livia, Morrissy, A Sorana, Marra, Marco A, Huang, Xi, Malkin, David, Ayrault, Olivier, Ramaswamy, Vijay, Puente, Xose S, Calarco, John A, Stein, Lincoln, Taylor, Michael D

“…Recurrent somatic single nucleotide variants (SNVs) in cancer are largely confined to protein-coding genes, and are rare in most paediatric cancers . Here we…”
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Recurrent non-coding U1-snRNA mutations drive cryptic splicing in Shh medulloblastoma by Suzuki, Hiromichi, Kumar, Sachin A., Shuai, Shimin, Diaz-Navarro, Ander, Gutierrez-Fernandez, Ana, De Antonellis, Pasqualino, Cavalli, Florence M. G., Juraschka, Kyle, Farooq, Hamza, Shibahara, Ichiyo, Vladoiu, Maria C., Zhang, Jiao, Abeysundara, Namal, Przelicki, David, Skowron, Patryk, Gauer, Nicole, Luu, Betty, Daniels, Craig, Wu, Xiaochong, Forget, Antoine, Momin, Ali, Wang, Jun, Dong, Weifan, Kim, Seung-Ki, Grajkowska, Wieslawa A., Jouvet, Anne, Fèvre-Montange, Michelle, Garrè, Maria Luisa, Nageswara Rao, Amulya A., Giannini, Caterina, Kros, Johan M., French, Pim J., Jabado, Nada, Ng, Ho-Keung, Poon, Wai Sang, Eberhart, Charles G., Pollack, Ian F., Olson, James M., Weiss, William A., Kumabe, Toshihiro, López-Aguilar, Enrique, Lach, Boleslaw, Massimino, Maura, Van Meir, Erwin G., Rubin, Joshua B., Vibhakar, Rajeev, Chambless, Lola B., Kijima, Noriyuki, Klekner, Almos, Bognár, László, Chan, Jennifer A., Faria, Claudia C., Ragoussis, Jiannis, Pfister, Stefan M., Goldenberg, Anna, Wechsler-Reya, Robert J., Bailey, Swneke D., Garzia, Livia, Morrissy, A. Sorana, Marra, Marco A., Huang, Xi, Malkin, David, Ayrault, Olivier, Ramaswamy, Vijay, Puente, Xose S., Calarco, John A., Stein, Lincoln, Taylor, Michael D.

“…Recurrent somatic single nucleotide variants (SNVs) in cancer are largely confined to protein coding genes, and are rare in most pediatric cancers 1 – 3 . We…”
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Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma by Nobre, Liana, Zapotocky, Michal, Khan, Sara, Fukuoka, Kohei, Fonseca, Adriana, McKeown, Tara, Sumerauer, David, Vicha, Ales, Grajkowska, Wieslawa A., Trubicka, Joanna, Li, Kay Ka Wai, Ng, Ho-Keung, Massimi, Luca, Lee, Ji Yeoun, Kim, Seung-Ki, Zelcer, Shayna, Vasiljevic, Alexandre, Faure-Conter, Cécile, Hauser, Peter, Lach, Boleslaw, van Veelen-Vincent, Marie-Lise, French, Pim J., Van Meir, Erwin G., Weiss, William A., Gupta, Nalin, Pollack, Ian F., Hamilton, Ronald L., Nageswara Rao, Amulya A., Giannini, Caterina, Rubin, Joshua B., Moore, Andrew S., Chambless, Lola B., Vibhakar, Rajeev, Ra, Young Shin, Massimino, Maura, McLendon, Roger E., Wheeler, Helen, Zollo, Massimo, Ferruci, Veronica, Kumabe, Toshihiro, Faria, Claudia C., Sterba, Jaroslav, Jung, Shin, López-Aguilar, Enrique, Mora, Jaume, Carlotti, Carlos G., Olson, James M., Leary, Sarah, Cain, Jason, Krskova, Lenka, Zamecnik, Josef, Hawkins, Cynthia E., Tabori, Uri, Huang, Annie, Bartels, Ute, Northcott, Paul A., Taylor, Michael D., Yip, Stephen, Hansford, Jordan R., Bouffet, Eric, Ramaswamy, Vijay

“…Over the past decade, wingless-activated (WNT) medulloblastoma has been identified as a candidate for therapy de-escalation based on excellent survival;…”
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Prognostic Value of Medulloblastoma Extent of Resection After Accounting for Molecular Subgroup: An Integrated Clinical and Molecular Analysis by Thompson, Eric M, Hielscher, Thomas, Bouffet, Eric, Remke, Marc, Luu, Betty, Gururangan, Sridharan, McLendon, Roger E, Bigner, Darell D, Lipp, Eric S, Perreault, Sebastien, Cho, Yoon-Jae, Grant, Gerald, Kim, Seung-Ki, Lee, Seung-Ki Kim Ji Yeoun, Rao, Amulya A Nageswara, Giannini, Caterina, Li, Kay Ka Wai, Ng, Ho-Keung, Yao, Yu, Kumabe, Toshihiro, Tominaga, Teiji, Grajkowska, Wieslawa A, Perek-Polnik, Marta, Low, David CY, Seow, Wan Tew, Chang, Kenneth TE, Mora, Jaume, Pollack, Ian F, Hamilton, Ronald L, Leary, Sarah, Moore, Andrew S., Ingram, Wendy J., Hallahan, Andrew R., Jouvet, Anne, Fèvre-Montange, Michelle, Vasiljevic, Alexandre, Faure-Conter, Cecile, Shofuda, Tomoko, Kagawa, Naoki, Hashimoto, Naoya, Jabado, Nada, Weil, Alexander G, Gayden, Tenzin, Wataya, Takafumi, Shalaby, Tarek, Grotzer, Michael, Zitterbart, Karel, Sterba, Jaroslav, Kren, Leos, Hortobágyi, Tibor, Klekner, Almos, László, Bognár, Pócza, Tímea, Hauser, Peter, Schüller, Ulrich, Jung, Shin, Jang, Woo-Youl, French, Pim J, Kros, Johan M, van Veelen, Marie-Lise C, Massimi, Luca, Leonard, Jeffrey R, Rubin, Joshua B, Vibhakar, Rajeev, Chambless, Lola B, Cooper, Michael K, Thompson, Reid C, Faria, Claudia C, Carvalho, Alice, Nunes, Sofia, Pimentel, José, Fan, Xing, Muraszko, Karin M, López-Aguilar, Enrique, Lyden, David, Garzia, Livia, Shih, David JH, Kijima, Noriyuki, Schneider, Christian, Adamski, Jennifer, Northcott, Paul A, Kool, Marcel, Jones, David TW, Chan, Jennifer A, Nikolic, Ana, Garre, Maria Luisa, Van Meir, Erwin G, Osuka, Satoru, Olson, Jeffrey J, Jahangiri, Arman, Castro, Brandyn A., Gupta, Nalin, Weiss, William A, Moxon-Emre, Iska, Mabbott, Donald J, Lassaletta, Alvaro, Hawkins, Cynthia E, Tabori, Uri, Drake, James, Kulkarni, Abhaya

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WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma by Zhukova, Nataliya, Ramaswamy, Vijay, Remke, Marc, Martin, Dianna C, Castelo-Branco, Pedro, Zhang, Cindy H, Fraser, Michael, Tse, Ken, Poon, Raymond, Shih, David J H, Baskin, Berivan, Ray, Peter N, Bouffet, Eric, Dirks, Peter, von Bueren, Andre O, Pfaff, Elke, Korshunov, Andrey, Jones, David T W, Northcott, Paul A, Kool, Marcel, Pugh, Trevor J, Pomeroy, Scott L, Cho, Yoon-Jae, Pietsch, Torsten, Gessi, Marco, Rutkowski, Stefan, Bognár, Laszlo, Cho, Byung-Kyu, Eberhart, Charles G, Conter, Cecile Faure, Fouladi, Maryam, French, Pim J, Grajkowska, Wieslawa A, Gupta, Nalin, Hauser, Peter, Jabado, Nada, Vasiljevic, Alexandre, Jung, Shin, Kim, Seung-Ki, Klekner, Almos, Kumabe, Toshihiro, Lach, Boleslaw, Leonard, Jeffrey R, Liau, Linda M, Massimi, Luca, Pollack, Ian F, Ra, Young Shin, Rubin, Joshua B, Van Meir, Erwin G, Wang, Kyu-Chang, Weiss, William A, Zitterbart, Karel, Bristow, Robert G, Alman, Benjamin, Hawkins, Cynthia E, Malkin, David, Clifford, Steven C, Pfister, Stefan M, Taylor, Michael D, Tabori, Uri

“…TP53 mutations confer subgroup specific poor survival for children with medulloblastoma. We hypothesized that WNT activation which is associated with improved…”
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