Search Results - "GRAHAM, GERRY J."
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1
Homing and mobilization in the stem cell niche
Published in Trends in Cell Biology (01-06-1999)“…All mature blood cells are derived from the haemopoietic stem cell (HSC). In common with all other haemopoietic cells, stem cells are mobile, and it is this…”
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Book Review Journal Article -
2
IL‐33 induces skin inflammation with mast cell and neutrophil activation
Published in European journal of immunology (01-08-2011)“…Psoriasis is a common chronic autoimmune condition of the skin characterized by hyperplasia of epidermal keratinocytes associated with pro‐inflammatory…”
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Journal Article -
3
IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Rα in T cells
Published in Blood (22-04-2010)“…Interleukin-7 (IL-7) is an essential cytokine for T-cell development and homeostasis. It is well established that IL-7 promotes the transcriptional…”
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Journal Article -
4
Liver X receptor agonism promotes articular inflammation in murine collagen‐induced arthritis
Published in Arthritis and rheumatism (01-09-2009)“…Objective Liver X receptors (LXRs) have previously been implicated in the regulation of inflammation and have, in general, been ascribed an antiinflammatory…”
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Journal Article -
5
Total Deletion of in Vivo Telomere Elongation Capacity: An Ambitious but Possibly Ultimate Cure for All Age-Related Human Cancers
Published in Annals of the New York Academy of Sciences (01-06-2004)“…: Despite enormous effort, progress in reducing mortality from cancer remains modest. Can a true cancer “cure” ever be developed, given the vast versatility…”
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Journal Article -
6
Gene Expression Profiling in Quiescent Stem Cells from Normal and Chronic Myeloid Leukaemia Patients
Published in Blood (16-11-2004)“…Earlier studies have shown that Ph+ quiescent cells exist in chronic myeloid leukaemia (CML) (Blood (1999)94:2056) and we have previously shown that these…”
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Journal Article -
7
IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Ralpha in T cells
Published in Blood (22-04-2010)“…Interleukin-7 (IL-7) is an essential cytokine for T-cell development and homeostasis. It is well established that IL-7 promotes the transcriptional…”
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Journal Article -
8
Use of 5-fluorouracil to analyze the effect of macrophage inflammatory protein-1α on long-term reconstituting stem cells in vivo
Published in Blood (15-03-1993)“…A macrophage-derived inhibitor of early hematopoietic progenitors (colony-forming unit-spleen, CFU-A) called stem cell inhibitor was found to be identical to…”
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Journal Article