Search Results - "GRAHAM, Anne G"

Pyrazole Urea-Based Inhibitors of p38 MAP Kinase:  From Lead Compound to Clinical Candidate by Regan, John, Breitfelder, Steffen, Cirillo, Pier, Gilmore, Thomas, Graham, Anne G, Hickey, Eugene, Klaus, Bernhard, Madwed, Jeffrey, Moriak, Monica, Moss, Neil, Pargellis, Chris, Pav, Sue, Proto, Alfred, Swinamer, Alan, Tong, Liang, Torcellini, Carol

“…We report on a series of N-pyrazole, N‘-aryl ureas and their mode of binding to p38 mitogen activated protein kinase. Importantly, a key binding domain that is…”
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Toning Down Abraham: Arthur Golding’s 1577 Translation, A Tragedie of Abraham’s Sacrifice by Graham, Anne G.

“…Arthur Golding was a prolific Elizabethan translator, most famous for his rendering of Ovid’s Metamorphoses. In 1577, he translated Théodore de Bèze’s 1550…”
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Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site by Pargellis, Christopher, Tong, Liang, Churchill, Laurie, Cirillo, Pier F, Gilmore, Thomas, Graham, Anne G, Grob, Peter M, Hickey, Eugene R, Moss, Neil, Pav, Susan, Regan, John

“…The p38 MAP kinase plays a crucial role in regulating the production of proinflammatory cytokines, such as tumor necrosis factor and interleukin-1. Blocking…”
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Effect of Structural Modification of Enol−Carboxamide-Type Nonsteroidal Antiinflammatory Drugs on COX-2/COX-1 Selectivity by Lazer, Edward S, Miao, Clara K, Cywin, Charles L, Sorcek, Ronald, Wong, Hin-Chor, Meng, Zhaoxing, Potocki, Ian, Hoermann, MaryAnn, Snow, Roger J, Tschantz, Matt A, Kelly, Terence A, McNeil, Daniel W, Coutts, Simon J, Churchill, Laurie, Graham, Anne G, David, Eva, Grob, Peter M, Engel, Wolfhard, Meier, Hans, Trummlitz, Günter

“…Meloxicam (5), an NSAID in the enol−carboxamide class, was developed on the basis of its antiinflammatory activity and relative safety in animal models. In…”
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Structure−Activity Relationships of the p38α MAP Kinase Inhibitor 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796) by Regan, John, Capolino, Alison, Cirillo, Pier F, Gilmore, Thomas, Graham, Anne G, Hickey, Eugene, Kroe, Rachel R, Madwed, Jeffrey, Moriak, Monica, Nelson, Richard, Pargellis, Christopher A, Swinamer, Alan, Torcellini, Carol, Tsang, Michele, Moss, Neil

“…We report on the structure−activity relationships (SAR) of 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naphthalen-1-yl]urea (BIRB…”
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Translating Dramatic Texts in Sixteenth-Century England and France: Introduction / Traduire le texte dramatique au seizième siècle en Angleterre et en France : Introduction by GRAHAM, ANNE G., JUHÁSZ-ORMSBY, ÁGNES

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Théodore de Bèze et Antoine de Saint-Michel d’Avully, Réponse au gentilhomme savoisien ne se nommant pas, précédée de la Lettre d’un gentilhomme savoisien (1598). Édité par Alain Dufour by Graham, Anne G

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Translating Dramatic Texts in Sixteenth-Century England and France: Introduction by Graham, Anne G., Juhász-Ormsby, Ágnes

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Réponse au gentilhomme savoisien ne se nommant pas, précédée de la Lettre d'un gentilhomme savoisien (1598) by Théodore de Bèze and Antoine de Saint-Michel d'Avully (review) by Graham, Anne G

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Benzoxazolamines and Benzothiazolamines: Potent, Enantioselective Inhibitors of Leukotriene Biosynthesis with a Novel Mechanism of Action by Lazer, Edward S, Miao, Clara K, Wong, Hin-Chor, Sorcek, Ronald, Spero, Denice M, Gilman, Alex, Pal, Kollol, Behnke, Mark, Graham, Anne G

“…A series of benzoxazolamine and benzothiazolamine analogs that inhibit leukotriene (LT) biosynthesis are described. The initial lead, (S)-N-(benzothiazol-2-…”
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Antiinflammatory 2,6-di-tert-butyl-4-(2-arylethenyl)phenols by Lazer, Edward S, Wong, Hin Chor, Possanza, Genus J, Graham, Anne G, Farina, Peter R

“…A series of 2,6-di-tert-butyl-4-(2-arylethenyl)phenols was prepared and examined for their ability to inhibit cyclooxygenase and 5-lipoxygenase in vitro and…”
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Effect of structure on potency and selectivity in 2,6-disubstituted-4-(2-arylethenyl)phenol lipoxygenase inhibitors by Lazer, Edward S, Wong, Hin Chor, Wegner, Craig D, Graham, Anne G, Farina, Peter R

“…A series of 2,6-disubstituted 4-(2-arylethenyl)phenols with potent human neutrophil 5-lipoxygenase (5-LO) inhibiting activity (IC50S in the 10(-7) M range) and…”
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Quelques figures de monstres tragiques dans la littérature française des XVIe et XVIIe siècles by Graham, Anne G

“…This thesis explores the relationship between the monster and the tragic in 16th and 17th century French literature, in particular through the analysis of the…”
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Le « baiser ensanglanté » ou la dévoration sublime ? Lecture de Moderato Cantabile by Graham, Anne G.

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Quelques figures de monstres tragiques dans la litterature francaise des XVIe et XVIIe siecles by Graham, Anne G

“…This thesis explores the relationship between the monster and the tragic in 16th and 17th century French literature, in particular through the analysis of the…”
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Structure-activity relationships of the p38a MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naphtha len-1-yl]urea (BIRB 796) by REGAN, John, CAPOLINO, Alison, PARGELLIS, Christopher A, SWINAMER, Alan, TORCELLINI, Carol, TSANG, Michele, MOSS, Neil, CIRILLO, Pier F, GILMORE, Thomas, GRAHAM, Anne G, HICKEY, Eugene, KROE, Rachel R, MADWED, Jeffrey, MORIAK, Monica, NELSON, Richard

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Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796) by Regan, John, Capolino, Alison, Cirillo, Pier F, Gilmore, Thomas, Graham, Anne G, Hickey, Eugene, Kroe, Rachel R, Madwed, Jeffrey, Moriak, Monica, Nelson, Richard, Pargellis, Christopher A, Swinamer, Alan, Torcellini, Carol, Tsang, Michele, Moss, Neil

“…We report on the structure-activity relationships (SAR) of 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naphthalen-1-yl]urea (BIRB…”
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Antiinflammatory 2-benzyl-4-sulfonyl-4H-isoquinoline-1,3-diones: Novel inhibitors of COX-2 by LAZER, E. S, SORCEK, R, CYWIN, C. L, THOME, D, POSSANZA, G. J, GRAHAM, A. G, CHURCHILL, L

“…A series of 2-benzyl-4-sulfonyl-4H-isoquinoline-1,3-diones was prepared. Members of this series are potent and selective inhibitors of cyclooxygenase-2 (COX-2)…”
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Antiinflammatory 2-benzyl-4-sulfonyl-4 H-isoquinoline-1,3-diones: Novel inhibitors of COX-2 by Lazer, Edward S., Sorcek, Ronald, Cywin, Charles L., Thome, Diane, Possanza, Genus J., Graham, Anne G., Churchill, Laurie

“…A series of 2-benzyl-4-sulfonyl-4 H-isoquinoline-1,3-diones was prepared. Members of this series are potent and selective inhibitors of cyclooxygenase-2…”
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Didon se sacrifiant d’Étienne Jodelle by Bonnet (book editor), Charlotte, Boutet (book editor), Anne, De Buzon (book editor), Christine, Gauthier (book editor), Élise, Graham (review author), Anne G.

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