Search Results - "GOWEN, L. C"

BRCA1 Required for Transcription-Coupled Repair of Oxidative DNA Damage by Gowen, Lori C., Avrutskaya, Anna V., Latour, Anne M., Koller, Beverly H., Leadon, Steven A.

“…The breast and ovarian cancer susceptibility gene BRCA1 encodes a zinc finger protein of unknown function. Association of the BRCA1 protein with the DNA repair…”
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Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol by BENNETT, L. M, MCALLISTER, K. A, MALPHURS, J, WARD, T, COLLINS, N. K, SEELY, J. C, GOWEN, L. C, KOLLER, B. H, DAVIS, B. J, WISEMAN, R. W

“…Women who inherit mutations in the breast cancer susceptibility genes, BRCA1 and BRCA2, are predisposed to the development of breast and ovarian cancer. We…”
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Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity by Glass, David J, Sleeman, Mark W, Wortley, Katherine E, Lai, Ka-Man V, Gowen, Lori C, Kintner, Jennifer, Kline, William O, Garcia, Karen, Stitt, Trevor N, Yancopoulos, George D, Wiegand, Stanley J

“…Genetic ablation of Inppl1, which encodes SHIP2 (SH2-domain containing inositol 5-phosphatase 2), was previously reported to induce severe insulin sensitivity,…”
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Microsatellite mutation rates in cancer cell lines deficient or proficient in mismatch repair by HANFORD, M. G, RUSHTON, B. C, GOWEN, L. C, FARBER, R. A

“…A selectable system has been used to determine mutation rates within a microsatellite sequence in human cancer cell lines with or without defects in mismatch…”
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Targeted Disruption of the Osteoblast/Osteocyte Factor 45 Gene (OF45) Results in Increased Bone Formation and Bone Mass by Gowen, Lori C., Petersen, Donna N., Mansolf, Amy L., Qi, Hong, Stock, Jeffrey L., Tkalcevic, George T., Simmons, Hollis A., Crawford, David T., Chidsey-Frink, Kristen L., Ke, Hua Zhu, McNeish, John D., Brown, Thomas A.

“…We have previously described osteoblast/osteocyte factor 45 (OF45), a novel bone-specific extracellular matrix protein, and demonstrated that its expression is…”
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BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene by Snouwaert, J N, Gowen, L C, Latour, A M, Mohn, A R, Xiao, A, DiBiase, L, Koller, B H

“…BRCA1 is a nuclear phosphoprotein that has been classified as a tumor suppressor based on the fact that women carrying a mutated copy of the BRCA1 gene are at…”
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Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities by Gowen, Lori C, Johnson, B. Lee, Latour, Anne M, Sulik, Kathleen K, Koller, Beverly H

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Mammary tumor formation in p53- and BRCA1-deficient mice by CRESSMAN, V. L, BACKLUND, D. C, HICKS, E. M, GOWEN, L. C, GODFREY, V, KOLLER, B. H

“…The inheritance of a mutant copy of the BRCA1 gene greatly increases a woman's lifetime risk for ovarian and breast cancer. While a homologous gene has been…”
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Chromosome and interphase analysis of placental mosaicism in intrauterine growth retardation by Krishnamoorthy, A, Gowen, L C, Boll, K E, Knuppel, R A, Sciorra, L J

“…Confined placental mosaicism is found in a higher percentage of cases of unexplained intrauterine growth retardation (IUGR) than in those of normal…”
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VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature by Kamba, Tomomi, Tam, Betty Y Y, Hashizume, Hiroya, Haskell, Amy, Sennino, Barbara, Mancuso, Michael R, Norberg, Scott M, O'Brien, Shaun M, Davis, Rachel B, Gowen, Lori C, Anderson, Keith D, Thurston, Gavin, Joho, Shuji, Springer, Matthew L, Kuo, Calvin J, McDonald, Donald M

“…Unlike during development, blood vessels in the adult are generally thought not to require VEGF for normal function. However, VEGF is a survival factor for…”
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Retraction by Gowen, L C, Avrutskaya, A V, Latour, A M, Koller, B H, Leadon SA

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Erratum: Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity by Sleeman, M W, Wortley, K E, Lai, K-M V, Gowen, L C, Kintner, J, Kline, W O, Garcia, K, Stitt, T N, Yancopoulos, G D, Wiegand, S J, Glass, D J

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BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a Brca1 transgene: Oncogenes in development by SNOUWAERT, J. N, GOWEN, L. C, LATOUR, A. M, MOHN, A. R, XIAO, A, DIBIASE, L, KOLLER, B. H

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Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5 by Macdonald, L.E, Wortley, K.E, Gowen, L.C, Anderson, K.D, Murray, J.D, Poueymirou, W.T, Simmons, M.V, Barber, D, Valenzuela, D.M, Economides, A.N

“…We identified a glycoprotein hormone beta-subunit (OGH, also called GPB5) that, as a heterodimer with the alpha-subunit GPA2, serves as a second ligand for the…”
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Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities by Gowen, L C, Johnson, B L, Latour, A M, Sulik, K K, Koller, B H

“…The breast and ovarian cancer susceptibility gene, BRCA1, has been cloned and shown to encode a zinc-finger protein of unknown function. Mutations in BRCA1…”
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BRCA 1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities by Gowen, L C, Johnson, B L, Latour, A M, Sulik, K K, Koller, B H

“…The breast and ovarian cancer susceptibility gene, BRCA1, has been cloned and shown to encode a zinc-finger protein of unknown function. Mutations in BRCA1…”
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Federal Court Abstention in Diversity of Citizenship Litigation by Gowen, Charles L, Izlar, William H

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