Search Results - "GOUKOS, Dimitris"
-
1
Carbapenemase-Producing Klebsiella pneumoniae Bloodstream Infections: Lowering Mortality by Antibiotic Combination Schemes and the Role of Carbapenems
Published in Antimicrobial agents and chemotherapy (01-04-2014)“…Carbapenemase-producing Klebsiella pneumoniae strains (CP-Kps) are currently among the most important nosocomial pathogens. An observational study was…”
Get full text
Journal Article -
2
Ex Vivo Evaluation of Glutamine Treatment in Sepsis and Trauma in a Human Peripheral Blood Mononuclear Cells Model
Published in Nutrients (01-01-2023)“…We aimed to assess the lipopolysaccharide (LPS), or heat shock (HS) induction, and glutamine-modulating effects on heat shock protein-90α (HSP90α) and…”
Get full text
Journal Article -
3
Glutamine suppresses Hsp72 not Hsp90α and is not inducing Th1, Th2, or Th17 cytokine responses in human septic PBMCs
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-10-2014)“…Abstract Objective l -Alanyl-glutamine (L-Ala-Gln) is a pharmaco-nutrient commonly used in nutrition regimens due to its immunomodulatory effects. In…”
Get full text
Journal Article -
4
Immunoparalysis: Clinical and immunological associations in SIRS and severe sepsis patients
Published in Cytokine (Philadelphia, Pa.) (01-04-2017)“…This study was designed to identify changes in the monocytic membrane marker HLA-DR and heat shock proteins (HSPs) in relation to T-regulatory cells (T-regs)…”
Get full text
Journal Article -
5
Crohn's disease-associated mucosal factors regulate the expression of TNF-like cytokine 1A and its receptors in primary subepithelial intestinal myofibroblasts and intestinal epithelial cells
Published in Translational research : the journal of laboratory and clinical medicine (01-02-2017)“…Intestinal subepithelial myofibroblasts (SEMFs) exert a profibrotic role in Crohn's disease (CD). Tumor necrosis factor-like cytokine 1A (TL1A) and its…”
Get full text
Journal Article -
6
High serum lipopolysaccharide binding protein is associated with increased mortality in patients with decompensated cirrhosis
Published in Liver international (01-04-2017)“…Background & Aims Lipopolysaccharide‐binding‐protein (LBP) is an acute‐phase‐protein produced by hepatocytes. Changes in LBP are associated with the dynamics…”
Get full text
Journal Article -
7
Increased glucocorticoid receptor expression in sepsis is related to heat shock proteins, cytokines, and cortisol and is associated with increased mortality
Published in Intensive care medicine experimental (01-12-2017)“…Background The purposes of this study are to examine if the human glucocorticoid receptor (hGR) isoform-α mRNA and hGR protein expressions are deficient in the…”
Get full text
Journal Article -
8
Comparative study of candidate housekeeping genes for quantification of target gene messenger RNA expression by real-time PCR in patients with inflammatory bowel disease
Published in Inflammatory bowel diseases (01-12-2013)“…Mucosal expression of immunological mediators is modified in inflammatory bowel disease (IBD). Quantification of target gene messenger RNA (mRNA) transcripts…”
Get full text
Journal Article -
9
Response to Lipopolysaccharide binding protein predicts decompensated cirrhosis mortality? It is too early
Published in Liver international (01-07-2017)Get full text
Journal Article -
10
Glutamine suppresses Hsp72 not Hsp90[alpha] and is not inducing Th1, Th2, or Th17 cytokine responses in human septic PBMCs
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-10-2014)“…Objective l-Alanyl-glutamine (L-Ala-Gln) is a pharmaco-nutrient commonly used in nutrition regimens due to its immunomodulatory effects. In critically ill…”
Get full text
Journal Article -
11
Glutamine May Repress the Weak LPS and Enhance the Strong Heat Shock Induction of Monocyte and Lymphocyte HSP72 Proteins but May Not Modulate the HSP72 mRNA in Patients with Sepsis or Trauma
Published in BioMed research international (01-01-2015)“…Objective. We assessed the lipopolysaccharide (LPS) or heat shock (HS) induction of heat shock protein-72 (HSP72) in peripheral blood mononuclear cells (PBMCs)…”
Get full text
Journal Article -
12
Predictors of tissue healing in ulcerative colitis patients treated with anti-TNF
Published in Digestive and liver disease (01-01-2017)“…Abstract Aim To identify factors predicting mucosal healing in ulcerative colitis patients treated with anti-TNFα agents with or without azathioprine. Methods…”
Get full text
Journal Article -
13
Systemic levels of human β-defensin 1 are elevated in patients with cirrhosis
Published in Annals of gastroenterology (01-01-2016)“…Bacterial translocation (BT) commonly occurs in cirrhosis. Reliable biomarkers for BT are currently lacking. Human beta defensin-1 (hBD-1) is a member of the…”
Get full text
Journal Article -
14
Genetic basis of aminoglycoside resistance following changes in aminoglycoside prescription patterns
Published in Journal of chemotherapy (Florence) (01-08-2013)“…Aminoglycosides (AG) offer an important therapeutic option for the treatment of infections caused by multiresistant Enterobacteriaceae. We observed a change in…”
Get full text
Journal Article