Search Results - "GOUGH, Kevin C"

REVIEW: The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology by Rees, Helen C, Maddison, Ben C, Middleditch, David J, Patmore, James R.M, Gough, Kevin C, Crispo, Erika

“…Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations,…”
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Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of the great crested newt (Triturus cristatus) by Harper, Lynsey R., Lawson Handley, Lori, Hahn, Christoph, Boonham, Neil, Rees, Helen C., Gough, Kevin C., Lewis, Erin, Adams, Ian P., Brotherton, Peter, Phillips, Susanna, Hänfling, Bernd

“…Environmental DNA (eDNA) analysis is a rapid, cost‐effective, non‐invasive biodiversity monitoring tool which utilises DNA left behind in the environment by…”
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Recombinant ovine prion protein can be mutated at position 136 to improve its efficacy as an inhibitor of prion propagation by Kopycka, Katarzyna, Maddison, Ben C., Gough, Kevin C.

“…Prion diseases are progressive neurodegenerative disorders with no effective therapeutics. The central event leading to the pathology in the diseases is the…”
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A Trematode Parasite Derived Growth Factor Binds and Exerts Influences on Host Immune Functions via Host Cytokine Receptor Complexes by Sulaiman, Azad A, Zolnierczyk, Katarzyna, Japa, Ornampai, Owen, Jonathan P, Maddison, Ben C, Emes, Richard D, Hodgkinson, Jane E, Gough, Kevin C, Flynn, Robin J

“…The trematode Fasciola hepatica is responsible for chronic zoonotic infection globally. Despite causing a potent T-helper 2 response, it is believed that…”
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The Chronic Stages of Bovine Fasciola hepatica Are Dominated by CD4 T-Cell Exhaustion by Sachdev, Divya, Gough, Kevin C, Flynn, Robin J

“…infection of ruminants leads to non-resolving chronic infection, as patency develops, there is switching to a TGF-β and IL-10 led response. Here, we explore…”
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The application of eDNA for monitoring of the Great Crested Newt in the UK by Rees, Helen C., Bishop, Keith, Middleditch, David J., Patmore, James R. M., Maddison, Ben C., Gough, Kevin C.

“…Current ecological surveys for great crested newts are time‐consuming and expensive and can only be carried out within a short survey window. Additional survey…”
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Prion transmission: Prion excretion and occurrence in the environment by Gough, Kevin C., Maddison, Ben C.

“…Prion diseases range from being highly infectious, for example scrapie and CWD which show facile transmission between susceptible individuals, to showing…”
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Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents by Marín-Moreno, Alba, Benestad, Sylvie L, Barrio, Tomas, Pirisinu, Laura, Espinosa, Juan Carlos, Tran, Linh, Huor, Alvina, Di Bari, Michele Angelo, Eraña, Hasier, Maddison, Ben C, D'Agostino, Claudia, Fernández-Borges, Natalia, Canoyra, Sara, Jerez-Garrido, Nuria, Castilla, Joaquín, Spiropoulos, John, Bishop, Keith, Gough, Kevin C, Nonno, Romolo, Våge, Jorn, Andréoletti, Olivier, Torres, Juan María

“…The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and confirmed by western blotting and immunohistochemistry in the brain stem…”
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Therapeutic Phage Display-Derived Single-Domain Antibodies for Pandemic Preparedness by Daly, Janet M, Lim, Theam Soon, Gough, Kevin C

“…Driven by necessity, the COVID-19 pandemic caused by SARS-CoV-2 has accelerated the development and implementation of new vaccine platforms and other viral…”
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BSE can propagate in sheep co-infected or pre-infected with scrapie by Chong, Angela, Foster, James D., Goldmann, Wilfred, Gonzalez, Lorenzo, Jeffrey, Martin, O’Connor, Matthew J., Bishop, Keith, Maddison, Ben C., Houston, E. Fiona, Gough, Kevin C., Hunter, Nora

“…To understand the possible role of mixed-prion infections in disease presentation, the current study reports the co-infection of sheep with bovine spongiform…”
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Applications and limitations of measuring environmental DNA as indicators of the presence of aquatic animals by Rees, Helen C., Gough, Kevin C., Middleditch, David J., Patmore, James R. M., Maddison, Ben C.

“…1. In Rees et al. (2014b), we reviewed the current status of environmental DNA (eDNA) to monitor aquatic populations. Our aim was to focus on discussion of…”
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The detection of great crested newts year round via environmental DNA analysis by Rees, Helen C, Baker, Claire A, Gardner, David S, Maddison, Ben C, Gough, Kevin C

“…Analysis of environmental DNA (eDNA) is a method that has been used for the detection of various species within water bodies. The great crested newt (Triturus…”
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Sensitive recovery of recombinant antibody clones after their in silico identification within NGS datasets by Spiliotopoulos, Anastasios, Owen, Jonathan.P., Maddison, Ben.C., Dreveny, Ingrid, Rees, Helen.C., Gough, Kevin.C.

“…Recently the analytical power of the latest high throughput next generation DNA sequencing platforms has been used to analyse phage that have been selected…”
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Environmental Sources of Scrapie Prions by MADDISON, Ben C, BAKER, Claire A, TERRY, Linda A, BELLWORTHY, Susan J, THORNE, Leigh, REES, Helen C, GOUGH, Kevin C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Prions Are Secreted into the Oral Cavity in Sheep with Preclinical Scrapie by Maddison, Ben C., Rees, Helen C., Baker, Claire A., Taema, Maged, Bellworthy, Susan J., Thorne, Leigh, Terry, Linda A., Gough, Kevin C.

“…A major concern in prion disease transmission is the spread of the disease agent by means of secretions and excretions. We analyzed buccal swab samples…”
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Oral Secretion of Infectious Scrapie Prions Occurs in Preclinical Sheep with a Range of PRNP Genotypes by Gough, Kevin C, Baker, Claire A, Rees, Helen C, Terry, Linda A, Spiropoulos, John, Thorne, Leigh, Maddison, Ben C

“…Preclinical sheep with the highly scrapie-susceptible VRQ/VRQ PRNP genotype secrete prions from the oral cavity. In order to further understand the…”
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Detection of prions in the faeces of sheep naturally infected with classical scrapie by Terry, Linda A, Howells, Laurence, Bishop, Keith, Baker, Claire A, Everest, Sally, Thorne, Leigh, Maddison, Ben C, Gough, Kevin C

“…Classical scrapie is a naturally transmitted prion disease of sheep and goats. Contaminated environments may contribute to the spread of disease and evidence…”
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The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology by Rees, Helen C., Maddison, Ben C., Middleditch, David J., Patmore, James R.M., Gough, Kevin C.

“…1. Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations,…”
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Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines by Smith, Claire M, Fry, Stephen C, Gough, Kevin C, Patel, Alexandra J F, Glenn, Sarah, Goldrick, Marie, Roberts, Ian S, Whitelam, Garry C, Andrew, Peter W

“…Bacterial polysaccharides have numerous clinical or industrial uses. Recombinant plants could offer the possibility of producing bacterial polysaccharides on a…”
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Isolation of phage-antibodies against Eimeria species that infect chickens by Angani, Mary T., Owen, Jonathan P., Maddison, Ben C., Gough, Kevin C.

“…Eimeria is one of the most economically important pathogens in poultry production. Diagnosis of infection has the potential to inform treatment and prevention…”
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