Search Results - "GOSS, C"

Phase II studies of nebulised Arikace in CF patients with Pseudomonas aeruginosa infection by Clancy, J P, Dupont, L, Konstan, M W, Billings, J, Fustik, S, Goss, C H, Lymp, J, Minic, P, Quittner, A L, Rubenstein, R C, Young, K R, Saiman, L, Burns, J L, Govan, J R W, Ramsey, B, Gupta, R

“…Arikace is a liposomal amikacin preparation for aerosol delivery with potent Pseudomonas aeruginosa killing and prolonged lung deposition. To examine the…”
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The age, isotopic signature and significance of the youngest Mesozoic granitoids in the Jiaodong Terrane, Shandong Province, North China Craton by Goss, Sarah C., Wilde, Simon A., Wu, Fuyuan, Yang, Jinhui

“…Most Cretaceous granitoids in the Jiaodong Terrane of Shandong Province, North China Craton, were intruded between ~ 130 and 122 Ma. However, four granitoid…”
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Surfactant Phospholipid Kinetics in Ventilated Children after Therapeutic Surfactant Supplementation by Goss, Victoria M, Dushianthan, Ahilanandan, McCorkell, Jenni, Morton, Katy, Goss, Kevin C W, Marsh, Michael J, Pappachan, John V, Postle, Anthony D

“…Acute lung Injury leads to alterations in surfactant lipid composition and metabolism. Although several mechanisms contribute to dysregulated surfactant…”
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Contribution of Noncanonical Antigens to Virulence and Adaptive Immunity in Human Infection with Enterotoxigenic E. coli by Kuhlmann, F M, Laine, R O, Afrin, S, Nakajima, R, Akhtar, M, Vickers, T, Parker, K, Nizam, N N, Grigura, V, Goss, C W, Felgner, P L, Rasko, D A, Qadri, F, Fleckenstein, J M

“…Enterotoxigenic (ETEC) contributes significantly to the substantial burden of infectious diarrhea among children living in low- and middle-income countries. In…”
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C-reactive protein (CRP) as a biomarker of pulmonary exacerbation presentation and treatment response by VanDevanter, DR, Heltshe, SL, Skalland, M, West, NE, Sanders, DB, Goss, CH, Flume, PA

“…•C-reactive protein (CRP) is a biomarker of systemic inflammation of interest in CF.•We studied CRP as a biomarker of response to pulmonary exacerbation (PEx)…”
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Surfactant replacement therapy for respiratory distress syndrome in preterm infants: United Kingdom national consensus by Banerjee, Sujoy, Fernandez, Ramon, Fox, Grenville F., Goss, Kevin C. W., Mactier, Helen, Reynolds, Peter, Sweet, David G., Roehr, Charles C.

“…Our aim was to develop consensus recommendations from United Kingdom (UK) neonatal specialists on the use of surfactant for the management of respiratory…”
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Association of site of treatment with clinical outcomes following intravenous antimicrobial treatment of a pulmonary exacerbation by Sanders, D.B., Khan, U., Heltshe, S.L., Skalland, M., West, N.E., VanDevanter, D.R., Goss, C.H., Flume, P.A.

“…•The impact of home vs hospital care is an important clinical question in the treatment of pulmonary exacerbations (PEx).•We assessed treatment responses for…”
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Assessing the profile and utility of diplomates in occupational medicine by Johnson, F, Madan, I, Pattani, S, De Bono, A, Boorman, S, Goss, C, Parsons, V

“…The utility of the occupational medicine diploma in the UK is yet to be explored. The NHS 'Growing Occupational Health (OH) and Wellbeing' programme provides…”
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Association between Stenotrophomonas maltophilia and lung function in cystic fibrosis by Goss, C H, Mayer-Hamblett, N, Aitken, M L, Rubenfeld, G D, Ramsey, B W

“…Background:Stenotrophomonas maltophilia (SM) is a Gram-negative non-fermenting bacteria cultured from the sputum of patients with cystic fibrosis (CF). To…”
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Comparison of three solid phase extraction sorbents for the isolation of THM precursors from manitoban surface waters by Goss, C.D., Wiens, R., Gorczyca, B., Gough, K.M.

“…Three prepackaged solid phase extraction (SPE) cartridges: two modified styrene divinylbenzene, Bond Elut ENV and Bond Elut PPL (Varian), and one…”
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Changes in symptom scores as a potential clinical endpoint for studies of cystic fibrosis pulmonary exacerbation treatment by VanDevanter, DR, Heltshe, SL, Sanders, DB, West, NE, Skalland, M, Flume, PA, Goss, CH

“…•The STOP-OB study collected respiratory symptom changes with exacerbation treatment.•Symptoms were collected by Chronic Respiratory Infection Symptom Score…”
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Building global development strategies for cf therapeutics during a transitional cftr modulator era by Mayer-Hamblett, N., van Koningsbruggen-Rietschel, S., Nichols, D.P., VanDevanter, D.R., Davies, J.C., Lee, T., Durmowicz, A.G., Ratjen, F., Konstan, M.W., Pearson, K., Bell, S.C., Clancy, J.P., Taylor-Cousar, J.L., De Boeck, K., Donaldson, S.H., Downey, D.G., Flume, P.A., Drevinek, P., Goss, C.H., Fajac, I., Magaret, A.S., Quon, B.S., Singleton, S.M., VanDalfsen, J.M., Retsch-Bogart, G.Z.

“…•Advancement of the CF therapeutics pipeline remains an important goal.•Availability of CFTR modulators impacts future CF clinical development.•Global…”
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Antipseudomonal treatment decisions during CF exacerbation management by VanDevanter, D.R., West, N.E., Sanders, D.B., Skalland, M., Goss, C.H., Flume, P.A., Heltshe, S.L.

“…•Exacerbation treatment outcomes for STOP2 subjects with P. aeruginosa were studied.•Outcomes were compared across number of antipseudomonal classes used.•Lung…”
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A longitudinal study of naloxone opioid overdose awareness and reversal training for first-year medical students: specific elements require reinforcement by Sandhu, Reena K, Heller, Michael V, Buckanavage, Jack, Haslund-Gourley, Benjamin, Leckron, Joshua, Kupersmith, Brady, Goss, Nathaniel C, Samson, Kyle, Gadegbeku, Annette B

“…Abstract Background The opioid epidemic is a progressively worsening public health crisis that continues to impact healthcare system strategies such as…”
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Long-term treatment with oral N-acetylcysteine: Affects lung function but not sputum inflammation in cystic fibrosis subjects. A phase II randomized placebo-controlled trial by Conrad, C, Lymp, J, Thompson, V, Dunn, C, Davies, Z, Chatfield, B, Nichols, D, Clancy, J, Vender, R, Egan, M.E, Quittell, L, Michelson, P, Antony, V, Spahr, J, Rubenstein, R.C, Moss, R.B, Herzenberg, L.A, Goss, C.H, Tirouvanziam, R

“…Abstract Purpose To evaluate the effects of oral N-acetylcysteine (NAC), which replenishes systemic glutathione, on decreasing inflammation and improving lung…”
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Postnatal adaptations of phosphatidylcholine metabolism in extremely preterm infants: implications for choline and PUFA metabolism by Goss, Kevin CW, Goss, Victoria M, Townsend, J Paul, Koster, Grielof, Clark, Howard W, Postle, Anthony D

“…Lipid metabolism in pregnancy delivers PUFAs from maternal liver to the developing fetus. The transition at birth to diets less enriched in PUFA is especially…”
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Duration of Antibiotic Therapy in Non-cystic Fibrosis Bronchiectasis by Somayaji, R., Goss, C. H.

“…Purpose of Review We conducted a review of the current evidence relating to antibiotic duration in the short- and long-term management of non-cystic fibrosis…”
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Rationalizing endpoints for prospective studies of pulmonary exacerbation treatment response in cystic fibrosis by VanDevanter, D.R, Heltshe, S.L, Spahr, J, Beckett, V.V, Daines, C.L, Dasenbrook, E.C, Gibson, R.L, Jain, R, Sanders, D.B, Goss, C.H, Flume, P.A

“…Abstract Background Given the variability in pulmonary exacerbation (PEx) management within and between Cystic Fibrosis (CF) Care Centers, it is possible that…”
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Exacerbations in cystic fibrosis · 1 : Epidemiology and pathogenesis by GOSS, Christopher H, BURNS, Jane L

“…With the improving survival of patients with cystic fibrosis (CF), the clinical spectrum of this complex multisystem disease continues to evolve. One of the…”
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People-centred care: new research needs and methods in doctor–patient communication. Challenges in mental health by Del Piccolo, L., Goss, C.

“…Communication in psychiatry is nowadays called to create bridges between different levels of observation (biological, functional and relational levels) and…”
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