Search Results - "GORUR, Aysegul"

Association of Mu-Opioid Receptor(MOR) Expression and Opioids Requirement With Survival in Patients With Stage I-III Pancreatic Ductal Adenocarcinoma by Zhang, Hao, Qu, Mengdi, Gorur, Aysegul, Sun, Zhirong, Cata, Juan P, Chen, Wankun, Miao, Changhong

“…The use of opioids in patients with metastatic pancreatic ductal adenocarcinoma (PDAC) is associated with shorter survival and not dependent on the expression…”
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ncRNA therapy with miRNA-22-3p suppresses the growth of triple-negative breast cancer by Gorur, Aysegul, Bayraktar, Recep, Ivan, Cristina, Mokhlis, Hamada Ahmed, Bayraktar, Emine, Kahraman, Nermin, Karakas, Didem, Karamil, Selda, Kabil, Nashwa N., Kanlikilicer, Pinar, Aslan, Burcu, Tamer, Lulufer, Wang, Zhihui, Cristini, Vittorio, Lopez-Berestein, Gabriel, Calin, George, Ozpolat, Bulent

“…Deregulation of noncoding RNAs, including microRNAs (miRs), is implicated in the pathogenesis of many human cancers, including breast cancer. Through extensive…”
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Comparison of microRNA profiles between benign and malignant salivary gland tumors in tissue, blood and saliva samples: a prospective, case-control study by Cinpolat, Ovgu, Unal, Zeynep Nil, Ismi, Onur, Gorur, Aysegul, Unal, Murat

“…Salivary gland tumors (SGTs) are rare head and neck malignancies consisting of a spectrum of tumors with different biological behaviors. In this study we aimed…”
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Determination of plasma microRNA for early detection of gastric cancer by Gorur, Aysegul, Balci Fidanci, Senay, Dogruer Unal, Nil, Ayaz, Lokman, Akbayir, Serin, Yildirim Yaroglu, Hatice, Dirlik, Musa, Serin, Mehmet Sami, Tamer, Lulufer

“…Gastric cancer is the fourth most prevalent malignancy worldwide and remains the second most common cause of cancer-related death globally. Understanding the…”
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Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats by Sari, A. Nihal, Kacan, Meltem, Unsal, Demet, Sahan Firat, Seyhan, Kemal Buharalioglu, C., Vezir, Ozden, Korkmaz, Belma, Cuez, Tuba, Canacankatan, Necmiye, Sucu, Nehir, Ayaz, Lokman, Tamer Gumus, Lulufer, Gorur, Aysegul, Tunctan, Bahar

“…The small G protein RhoA and its downstream effector Rho-kinase play an important role in various physiopathological processes including ischemia/reperfusion…”
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Fadu head and neck squamous cell carcinoma induces hyperexcitability of primary sensory neurons in an in vitro coculture model by Uhelski, Megan L., Gorur, Aysegul, Shi, Ted, Corrales, German, Du, Kim N., Li, Yan, Amit, Moran, Tatsui, Claudio E., Rhines, Laurence D., Dougherty, Patrick M., Cata, Juan P.

“…Currently, cancer pain is viewed as a process orchestrated by the release of pronociceptive molecules and the invasion of neural structures, referred to as…”
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A rat model to investigate quality of recovery after abdominal surgery by Cata, Juan P, Patiño, Miguel, Lacagnina, Michael J, Li, Jiahe, Gorur, Aysegul, Agudelo-Jimenez, Ruben, Wei, Bo, Hagberg, Carin A, Dougherty, Patrick M, Shureiqi, Imad, Yang, Peiying, Grace, Peter M

“…Major advances in therapies to optimize recovery after surgery have been limited by the lack of an animal model that can mimic major domains of postoperative…”
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BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia by Ozturk, Perihan, Kurutas, Ergul, Ataseven, Arzu, Dokur, Neslihan, Gumusalan, Yakup, Gorur, Ayşegul, Tamer, Lulufer, Inaloz, Serhat

“…Male pattern androgenetic alopecia is characterized by progressive hair loss from the scalp. It is known that imbalances of some trace elements play a role in…”
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Nociception and Pain: New Roles for Exosomes by Cata, Juan P., Uhelski, Megan L., Gorur, Aysegul, Dougherty, Patrick M.

“…The interchange of information from one cell to another relies on the release of hundreds of different molecules including small peptides, amino acids,…”
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Abstract 5027: The mu-opioid receptor antagonist methylnaltrexone can decrease tumorigenesis in head and neck squamous cell carcinoma by Gorur, Aysegul, Patino, Miguel, Shi, Ted, Takahashi, Hideaki, Myers, Jeffrey N., Cata, Juan P.

“…Head and neck cancer (HNC) is the sixth leading cause of cancer in the world, and the third most common neoplasia in developing countries [1]. Patients with…”
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Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats by Temiz-Resitoglu, Meryem, Kucukkavruk, Sefika Pinar, Guden, Demet Sinem, Cecen, Pelin, Sari, Ayse Nihal, Tunctan, Bahar, Gorur, Aysegul, Tamer-Gumus, Lulufer, Buharalioglu, Cuneyt Kemal, Malik, Kafait U., Sahan-Firat, Seyhan

“…Mammalian target of rapamycin (mTOR), a serine/threonine kinase plays an important role in various pathophysiological processes including cancer, metabolic…”
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Investigation of possible effects of microRNAs involved in regulation of lipid metabolism in the pathogenesis of atherosclerosis by Gorur, Aysegul, Celik, Ahmet, Yildirim, Didem Derici, Gundes, Ahmet, Tamer, Lulufer

“…Due to being stable in the circulatory system plasma miRNAs have been detected in various diseases including coronary artery disease (CAD) which is the major…”
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Role of Micro-RNA for Pain After Surgery: Narrative Review of Animal and Human Studies by Cata, Juan P., Gorur, Aysegul, Yuan, Xiaoyi, Berg, Nathaniel K., Sood, Anil K., Eltzschig, Holger K.

“…One of the most prevalent symptoms after major surgery is pain. When postoperative pain treatment is unsatisfactory, it can lead to poor surgical recovery,…”
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Mu-opioid receptor activation promotes in vitro and in vivo tumor growth in head and neck squamous cell carcinoma by Gorur, Aysegul, Patiño, Miguel, Takahashi, Hideaki, Corrales, German, Pickering, Curtis R., Gleber-Netto, Frederico O., Myers, Jeffrey N., Cata, Juan P.

“…In vitro and in vivo studies suggest that the mu-opioid receptor (MOR) is involved in tumorigenesis, and metastasis in cancer. In humans, the use of MOR…”
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Low doses of methylnaltrexone inhibits head and neck squamous cell carcinoma growth in vitro and in vivo by acting on the mu‐opioid receptor by Gorur, Aysegul, Patiño, Miguel, Shi, Ted, Corrales, German, Takahashi, Hideaki, Rangel, Roberto, Gleber‐Netto, Frederico O., Pickering, Curtis, Myers, Jeffrey N., Cata, Juan P.

“…The Mu‐opioid receptor (MOR) has been implicated in tumorigenesis and metastasis. Methylnaltrexone (MNTX), an antagonist of MOR, has shown to inhibit tumor…”
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Expression level of miRNAS in patients with gestational diabetes by Balci, Senay, Gorur, Aysegul, Derici Yıldırım, Didem, Cayan, Filiz, Tamer, Lulufer

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The role of opioids in cancer progression by Ramirez, Maria F., Gorur, Aysegul, Cata, Juan P.

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Persistent and Chronic Postoperative Opioid Use in a Cohort of Patients with Oral Tongue Squamous Cell Carcinoma by Cata, Juan P, Patino, Miguel, Gorur, Aysegul, Du, Kim N, Uhelski, Megan L, Myers, Jeffrey, Lai, Stephen, Rubin, M Laura, Dougherty, Patrick M, Owusu-Agyemang, Pascal

“…Abstract Background Recently, the concept of persistent postsurgical opioid use has been described for patients undergoing cancer surgery. Our hypothesis was…”
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The µ‐Opioid Receptor in Cancer and Its Role in Perineural Invasion: A Short Review and New Evidence by Cata, Juan P., Uhelski, Megan L., Gorur, Aysegul, Bhoir, Siddhant, Ilsin, Nisa, Dougherty, Patrick M.

“…Cancer is a significant public health problem worldwide. While there has been a steady decrease in the cancer death rate over the last two decades, the number…”
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Antioxidant and Neuroprotective Effects of L-arginine Administration After Traumatic Brain Injury and Hemorrhagic Shock in Rats by Berikol, Goksu Bozdereli, Berikol, Gurkan, Ayrik, Cuneyt, Kose, Ataman, Babus, Seyran Bozkurt, Gumus, Lulufer Tamer, Arpaci, Rabia Bozdogan, Dag, Ahmet, Ayan, Erhan, Gorur, Aysegul

“…To investigate the effect of fluid resuscitation and L-arginine administration on oxidant status markers, blood gases, lactate and apoptosis in the brain…”
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