Search Results - "GORI, Zina"

The Role of Autophagy in Aging by BERGAMINI, ETTORE, CAVALLINI, GABRIELLA, DONATI, ALESSIO, GORI, ZINA

“…:  Aging denotes a postmaturational deterioration of cells and organisms with the passage of time, an increased vulnerability to challenges and prevalence of…”
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The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction by Bergamini, Ettore, Cavallini, Gabriella, Donati, Alessio, Gori, Zina

“…Aging denotes a postmaturational deterioration of cells and organisms with the passage of time, an increased vulnerability to challenges and prevalence of…”
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Low level dietary restriction retards age-related dolichol accumulation by Cavallini, Gabriella, Donati, Alessio, Gori, Zina, Parentini, Ilaria, Bergamini, Ettore

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Ageing-related changes in the in vivo function of rat liver macroautophagy and proteolysis by Del Roso, Alessandra, Vittorini, Simona, Cavallini, Gabriella, Donati, Alessio, Gori, Zina, Masini, Matilde, Pollera, Maria, Bergamini, Ettore

“…Autophagy is a universal, highly regulated mechanism responsible for the degradation of long-lived proteins, cytomembranes and organelles during fasting and…”
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3-Hydroxy-3-methylglutaryl coenzyme A reductase deregulation and age-related hypercholesterolemia: A new role for ROS by Pallottini, Valentina, Martini, Chiara, Pascolini, Andrea, Cavallini, Gabriella, Gori, Zina, Bergamini, Ettore, Incerpi, Sandra, Trentalance, Anna

“…The microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCoAR) is the rate-limiting enzyme in cholesterol synthesis and is highly regulated by…”
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Mechanisms underlying the impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in aged rat liver by Pallottini, Valentina, Montanari, Laura, Cavallini, Gabriella, Bergamini, Ettore, Gori, Zina, Trentalance, Anna

“…As the main risk factor for cardiovascular disease, hypercholesterolemia is one of the most studied age-related metabolic alterations. In the liver,…”
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Age-related changes in the regulation of autophagic proteolysis in rat isolated hepatocytes by Donati, A, Cavallini, G, Paradiso, C, Vittorini, S, Pollera, M, Gori, Z, Bergamini, E

“…During intervals between meals, autophagy is a major source of nutrients and may remove damaged organelles and membranes. Age-related changes in the regulation…”
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Anti-aging effects of anti-lipolytic drugs by Donati, Alessio, Cavallini, Gabriella, Carresi, Cristiano, Gori, Zina, Parentini, Ilaria, Bergamini, Ettore

“…Genetic disruption of insulin and insulin-like signaling pathways may extend lifespan. Hyperinsulinemia and insulin resistance may accelerate aging. The…”
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Accumulation of Dolichol in Older Tissues Satisfies the Proposed Criteria To Be Qualified a Biomarker of Aging by Parentini, Ilaria, Cavallini, Gabriella, Donati, Alessio, Gori, Zina, Bergamini, Ettore

“…Criteria for defining biomarkers have been suggested. Accumulation of dolichol in tissues of older animals meets the following criteria: (a) levels of dolichol…”
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The Age-Related Accumulation of Protein Carbonyl in Rat Liver Correlates With the Age-Related Decline in Liver Proteolytic Activities by Vittorini, Simona, Paradiso, Cristina, Donati, Alessio, Cavallini, Gabriella, Masini, Matilde, Gori, Zina, Pollera, Maria, Bergamini, Ettore

“…Increases of protein carbonyl in animal tissues have been associated with the aging process. So far, the accumulation of oxidized proteins, highly susceptible…”
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Insulin, food restriction and the extension of lifespan: the mechanism of longevity by Bergamini, Ettore, Cavallini, Gabriella, Donati, Alessio, Gori, Zina

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Streptozotocin-induced functioning islet cell tumor in the rat: high frequency of induction and biological properties of the tumor cells by Masiello, P, Wollheim, C B, Gori, Z, Blondel, B, Bergamini, E

“…After a long latency, hormone-producing islet cell tumors are induced with high frequency by a single administration of streptozotocin and nicotinamide in the…”
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The age-related accumulation of dolichol in rat liver may correlate with expectation of life by DOLFI, Chiara, BERGAMINI, Ettore, CARRESI, Cristiano, CAVALLINI, Gabriella, DONATI, Alessio, MACCHERONI, Marco, PARENTINI, Ilaria, MARINO, Maria, GORI, Zina

“…In order to test the hypothesis that the ageing-related alteration in membrane lipids might reflect the biological age of rodents, the levels of liver dolichol…”
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Effect of increasing age on tissue dolichol levels in ad libitum fed and food-restricted rats by CAVALLINI, Gabriella, DOLFI, Chiara, DONATI, Alessio, MACCHERONI, Marco, PARENTINI, Ilaria, GORI, Zina, BERGAMINI, Ettore

“…In order to test the hypothesis that the ageing-related alteration in membrane lipids might reflect the biological age of rodents, we studied the effects of…”
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The effect of carbon tetrachloride and ultraviolet radiation on dolichol levels in liver cells isolated from 3- and 24-month-old male Sprague-Dawley rats by PARENTINI, Ilaria, BERGAMINI, Ettore, CECCHI, Lauretta, CAVALLINI, Gabriella, DONATI, Alessio, MACCHERONI, Marco, TAMBURINI, Ilaria, GORI, Zina

“…Dolichol (D) is a long-chain polyprenoid broadly distributed in the cell membranes, possibly endowed with a free-radical scavenging activity, whose…”
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Dolichol levels in younger and older rat hearts heterotopically transplanted in younger recipients by Cavallini, Gabriella, Parentini, Ilaria, Di Stefano, Rossella, Maccheroni, Marco, Masini, Matilde, Pollera, Maria, Gori, Zina, Masca, Franco, Bergamini, Ettore

“…Dolichol (D) levels increase dramatically in older tissue. An understanding of the exchangeability of D between tissues may be essential in order to understand…”
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Dolichol: a solar filter with uv-absorbing properties which can be photoenhanced by SGARBOSSA, Antonella, LENCI, Francesco, BERGAMINI, Ettore, BIZZARRI, Ranieri, CERBAI, Benedetta, SIGNORI, Francesca, GORI, Zina, MACCHERONI, Marco

“…Dolichol, the polyisoprenoid lipid found in all eukaryotic cells and suggested to represent a biomarker of aging, is inserted into cell membranes, also in…”
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The fate of dolichol in rat cells and tissues by CAVALLINI, Gabriella, BERGAMINI, Ettore, DI STEFANO, Rossella, DONATI, Alessio, MACCHERONI, Marco, MASINI, Matilde, MOSCA, Franco, PARENTINI, Ilaria, POLLERA, Maria, GORI, Zina

“…Dolichol (D) levels increase dramatically in older tissue. A better understanding of the fate of cell D and exchange between tissues could be essential for…”
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Towards an understanding of the anti-aging mechanism of caloric restriction by Cavallini, Gabriella, Donati, Alessio, Gori, Zina, Bergamini, Ettore

“…Accumulation of oxidatively altered cell components may play a role in the age-related cell deterioration and associated diseases. Caloric restriction is the…”
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Systemic Lymphoid Atrophy in Coxsackievirus B3-Infected Mice: Effects of Virus and Immunopotentiating Agents by Matteucci, Donatella, Toniolo, Antonio, Conaldi, Pier G., Basolo, Fulvio, Gori, Zina, Bendinelli, Mauro

“…Adult mice infected with coxsackievirus B3 (CB3) showed a generalized lymphoid involution. This effect was produced by most of the isolates and clones of CB3…”
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