Search Results - "GOON, Peter K. C"

HPV infection, anal intra-epithelial neoplasia (AIN) and anal cancer: current issues by Stanley, Margaret A, Winder, David M, Sterling, Jane C, Goon, Peter K C

“…Human papillomavirus (HPV) is well known as the major etiological agent for ano-genital cancer. In contrast to cervical cancer, anal cancer is uncommon, but is…”
Get full text

Spread of HTLV-I between Lymphocytes by Virus-Induced Polarization of the Cytoskeleton by Igakura, Tadahiko, Stinchcombe, Jane C., Peter K. C. Goon, Taylor, Graham P., Weber, Jonathan N., Griffiths, Gillian M., Tanaka, Yuetsu, Osame, Mitsuhiro, Charles R. M. Bangham

“…Cell contact is required for efficient transmission of human T cell leukemia virustype 1 (HTLV-I) between cells and between individuals, because naturally…”
Get full text

Analyses of human papillomavirus genotypes and viral loads in anogenital warts by Ball, Siolian L.R., Winder, David M., Vaughan, Katie, Hanna, Nashat, Levy, Jonathan, Sterling, Jane C., Stanley, Margaret A., Goon, Peter K.C.

“…Condylomata acuminata (genital warts) are the most common sexually transmitted viral diseases. These lesions are caused by infection with mucosal human…”
Get full text

De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma: A systematic review and meta-analysis of current clinical trials by Masterson, Liam, Moualed, Daniel, Liu, Zi Wei, Howard, James E.F, Dwivedi, Raghav C, Tysome, James R, Benson, Richard, Sterling, Jane C, Sudhoff, Holger, Jani, Piyush, Goon, Peter K.C

“…Abstract Iatrogenic complications associated with current treatment protocols for oropharyngeal squamous cell carcinoma are noted to cause high rates of acute…”
Get full text

Detection of specific HPV subtypes responsible for the pathogenesis of condylomata acuminata by Hawkins, Matthew G, Winder, David M, Ball, Siolian L R, Vaughan, Katie, Sonnex, Christopher, Stanley, Margaret A, Sterling, Jane C, Goon, Peter K C

“…BACKGROUND: The low-risk human papillomavirus types 6 and 11 are responsible for approximately 90% of anogenital wart cases, with approximately 190,000 new and…”
Get full text

HPV & head and neck cancer: a descriptive update by Goon, Peter K C, Stanley, Margaret A, Ebmeyer, Jörg, Steinsträsser, Lars, Upile, Tahwinder, Jerjes, Waseem, Bernal-Sprekelsen, Manuel, Görner, Martin, Sudhoff, Holger H

“…The incidence of head and neck squamous cell carcinoma (HNSCC) has been gradually increasing over the last three decades. Recent data have now attributed a…”
Get full text

High prevalence of HPV in non-cervical sites of women with abnormal cervical cytology by Crawford, Robin, Grignon, Anne-Laure, Kitson, Sarah, Winder, David M, Ball, Siolian L R, Vaughan, Katie, Stanley, Margaret A, Sterling, Jane C, Goon, Peter K C

“…Human papillomaviruses (HPV) are causally associated with ano-genital and a subset of head and neck cancers. Rising incidence of HPV+ anal cancers and head and…”
Get full text

Sensitive HPV detection in oropharyngeal cancers by Winder, David M, Ball, Siolian L R, Vaughan, Katie, Hanna, Nashat, Woo, Yin Ling, Fränzer, Jürgen-Theodor, Sterling, Jane C, Stanley, Margaret A, Sudhoff, Holger, Goon, Peter K C

“…Human papillomaviruses (HPV) are the aetiological agents of certain benign and malignant tumours of skin and mucosae; the most important of which is cervical…”
Get full text

Virus-Induced Cancers of the Skin and Mucosa: Are We Dealing with “Smoking Guns” or “Smoke and Mirrors” in the Operating Theatre? by Goon, Peter K. C., Goon, Patrick K. Y., Tan, Eunice K. H., Crawford, Robin A. F., Levell, Nick J., Sudhoff, Holger

“…Introduction Human papillomavirus (HPV) alone is thought to cause ~610,000 cases of cancer per year, and is the dominant aetiological agent for ano-genital…”
Get full text

The Role of CTLs in Persistent Viral Infection: Cytolytic Gene Expression in CD8+ Lymphocytes Distinguishes between Individuals with a High or Low Proviral Load of Human T Cell Lymphotropic Virus Type 1 by Vine, Alison M, Heaps, Adrian G, Kaftantzi, Lambrini, Mosley, Angelina, Asquith, Becca, Witkover, Aviva, Thompson, Gillian, Saito, Mineki, Goon, Peter K. C, Carr, Laura, Martinez-Murillo, Francisco, Taylor, Graham P, Bangham, Charles R. M

“…The proviral load in human T cell lymphotropic virus type 1 (HTLV-1) infection is typically constant in each infected host, but varies by >1000-fold between…”
Get full text

Human T cell lymphotropic virus (HTLV) type-1-specific CD8+T cells: Frequency and immunodominance hierarchy by GOON, Peter K. C, BIANCARDI, Alix, BANGHAM, Charles R. M, FAST, Noam, IGAKURA, Tadahiko, HANON, Emmanuel, MOSLEY, Angelina J, ASQUITH, Becca, GOULD, Keith G, MARSHALL, Sara, TAYLOR, Graham P

“…Human T cell lymphotropic virus type 1 (HTLV-1) causes HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). We used interferon- gamma…”
Get full text

5-Fluorouracil “Chemowraps” in the Treatment of Multiple Actinic Keratoses: A Norwich Experience by Goon, Peter K. C., Clegg, Rachel, Yong, Adrian S. W., Lee, Ava S. W., Lee, Kevin Y. C., Levell, Nick J., Tan, Eunice K. H., Shah, Syed N.

“…Introduction Topical 5-fluorouracil (5-FU) has been used to treat actinic keratosis for decades. It has been an important and effective treatment which the…”
Get full text

High frequencies of Th1-type CD4+ T cells specific to HTLV-1 Env and Tax proteins in patients with HTLV-1–associated myelopathy/tropical spastic paraparesis by Goon, Peter K.C., Hanon, Emmanuel, Igakura, Tadahiko, Tanaka, Yuetsu, Weber, Jonathan N., Taylor, Graham P., Bangham, Charles R.M.

“…CD4+ T cells are critical for inducing and maintaining efficient humoral and cellular immune responses to pathogens. The CD4+ T-cell response in human…”
Get full text

Human T Cell Lymphotropic Virus Type I (HTLV-I)-Specific CD4+ T Cells: Immunodominance Hierarchy and Preferential Infection with HTLV-I by Goon, Peter K. C, Igakura, Tadahiko, Hanon, Emmanuel, Mosley, Angelina J, Barfield, Anna, Barnard, Amanda L, Kaftantzi, Lambrini, Tanaka, Yuetsu, Taylor, Graham P, Weber, Jonathan N, Bangham, Charles R. M

“…CD4(+) T cells predominate in early lesions in the CNS in the inflammatory disease human lymphotropic T cell virus type I (HTLV-I)-associated…”
Get full text

High Circulating Frequencies of Tumor Necrosis Factor Alpha- and Interleukin-2-Secreting Human T-Lymphotropic Virus Type 1 (HTLV-1)-Specific CD4+ T Cells in Patients with HTLV-1-Associated Neurological Disease by Goon, Peter K C, Igakura, Tadahiko, Hanon, Emmanuel, Mosley, Angelina J, Asquith, Becca, Gould, Keith G, Taylor, Graham P, Weber, Jonathan N, Bangham, Charles R M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Activation of interleukin-13 expression in T cells from HTLV-1-infected individuals and in chronically infected cell lines by Chung, Hye-Kyung, Young, Howard A., Goon, Peter K.C., Heidecker, Gisela, Princler, Gerald L., Shimozato, Osamu, Taylor, Graham P., Bangham, Charles R.M., Derse, David

“…Human T-cell leukemia virus type 1 (HTLV-1) infection profoundly alters T-cell gene expression, and the dysregulated synthesis of cytokines could influence the…”
Get full text

Squamous Cell Carcinoma of the Skin has More Than Doubled Over the Last Decade in the UK by Goon, Peter K C, Greenberg, David C, Igali, Laszlo, Levell, Nick J

Get full text

Eccrine Porocarcinoma of the Skin is Rising in Incidence in the East of England by Goon, Peter K C, Gurung, Puran, Levell, Nick J, Subramanian, Priya, Yong, Adrian S W, Lee, Kevin Y C, Igali, Laszlo, Greenberg, David, Shah, Syed N, Tan, Eunice K H

Get full text

Molecular analyses of unselected head and neck cancer cases demonstrates that human papillomavirus transcriptional activity is positively associated with survival and prognosis by Masterson, Liam, Winder, David M, Ball, Siolian L R, Vaughan, Katie, Lehmann, Martin, Scholtz, Lars-Uwe, Sterling, Jane C, Sudhoff, Holger H, Goon, Peter K C

“…Human papillomavirus DNA detection in head and neck squamous cell carcinoma has been linked to improved patient prognosis. The main aims of the study was to…”
Get full text

Inflammatory phenotypes may be more important than age and comorbidities in predicting clinical outcomes in hospitalised patients with COVID-19 by Ngiam, Jinghao Nicholas, Koh, Matthew CY, Liong, Tze Sian, Sim, Meng Ying, Chhabra, Srishti, Goh, Wilson, Chew, Nicholas WS, Sia, Ching-Hui, Goon, Peter KC, Soong, John TY, Tambyah, Paul Anantharajah, Cove, Matthew Edward

“…•Hyperinflammatory phenotypes exist for critically ill patients with COVID-19.•This distinct phenotype is also demonstrated in relatively mild COVID-19…”
Get full text